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Depression and work impairement

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https://www.readbyqxmd.com/read/29347935/real-world-experience-of-women-using-extended-cycle-vs-monthly-cycle-combined-oral-contraception-in-the-united-states-the-national-health-and-wellness-survey
#1
Rossella E Nappi, Iñaki Lete, Lulu K Lee, Natalia M Flores, Marie-Christine Micheletti, Boxiong Tang
BACKGROUND: The real-world experience of women receiving extended-cycle combined oral contraception (COC) versus monthly-cycle COC has not been reported. METHODS: Data were from the United States 2013 National Health and Wellness Survey. Eligible women (18-50 years old, premenopausal, without hysterectomy) currently using extended-cycle COC (3 months between periods) were compared with women using monthly-cycle COC. Treatment satisfaction (1 "extremely dissatisfied" to 7 "extremely satisfied"), adherence (8-item Morisky Medication Adherence Scale©), menstrual cycle-related symptoms, health-related quality of life (HRQOL) and health state utilities (Medical Outcomes Short Form Survey-36v2®), depression (9-item Patient Health Questionnaire), sleep difficulties, Work Productivity and Activity Impairment-General Health, and healthcare resource use were assessed using one-way analyses of variance, chi-square tests, and generalized linear models (adjusted for covariates)...
January 18, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29342446/the-impact-of-happy-and-angry-faces-on-working-memory-in-depressed-adolescents
#2
Laura Wante, Sven C Mueller, Sofie Cromheeke, Caroline Braet
Recent cognitive models suggest that the ability to control emotional information in working memory (WM) may be implicated in the etiology and maintenance of depression. However, few studies have examined the effects of processing relevant and irrelevant emotional stimuli on WM performance in depressed adolescents. In the current study, depressed adolescents (n = 27) and healthy adolescents (n = 49) completed two versions of an emotional n-back task: a low WM load (0-back) task and a high WM load (2-back) task...
January 14, 2018: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29332631/treatment-utilization-and-barriers-to-treatment-among-individuals-with-olfactory-reference-syndrome-ors
#3
Jennifer L Greenberg, Noah C Berman, Valerie Braddick, Rachel Schwartz, Suraj S Mothi, Sabine Wilhelm
OBJECTIVE: Olfactory reference syndrome (ORS) is characterized by a preoccupation that one is emitting a foul or offensive odor. Despite the profound psychosocial impact of ORS, many patients do not receive appropriate treatment, and there is no empirical research on treatment-seeking behavior in ORS. This study investigated treatment utilization patterns and barriers to treatment in individuals with ORS. METHOD: 253 subjects completed an online survey between January-March 2010...
February 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29331082/mechanistic-target-of-rapamycin-complex-1-and-2-in-human-temporal-lobe-epilepsy
#4
Delia M Talos, Leah M Jacobs, Sarah Gourmaud, Carlos A Coto, Hongyu Sun, Kuei-Cheng Lim, Timothy H Lucas, Kathryn A Davis, Maria Martinez-Lage, Frances E Jensen
OBJECTIVE: Temporal lobe epilepsy (TLE) is a chronic epilepsy syndrome defined by seizures and progressive neurological disabilities, including cognitive impairments, anxiety and depression. Here, human TLE specimens were investigated focusing on the mechanistic target of rapamycin (mTOR) Complex 1 (mTORC1) and Complex 2 (mTORC2) activities in the brain, as both pathways may represent unique targets for treatment. METHODS: Surgically resected hippocampal and temporal lobe samples from therapy-resistant TLE patients were analyzed by Western blotting to quantify the expression of established mTORC1 and mTORC2 activity markers and upstream or downstream signaling pathways involving the two complexes...
January 13, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29326145/return-to-work-and-participation-in-society-after-out-of-hospital-cardiac-arrest
#5
Gisela Lilja, Niklas Nielsen, John Bro-Jeppesen, Hannah Dunford, Hans Friberg, Caisa Hofgren, Janneke Horn, Angelo Insorsi, Jesper Kjaergaard, Fredrik Nilsson, Paolo Pelosi, Tineke Winters, Matt P Wise, Tobias Cronberg
BACKGROUND: The aim of this study was to describe out-of-hospital cardiac arrest (OHCA) survivors' ability to participate in activities of everyday life and society, including return to work. The specific aim was to evaluate potential effects of cognitive impairment. METHODS AND RESULTS: Two hundred eighty-seven OHCA survivors included in the TTM trial (Target Temperature Management) and 119 matched control patients with ST-segment-elevation myocardial infarction participated in a follow-up 180 days post-event that included assessments of participation, return to work, emotional problems, and cognitive impairment...
January 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29323521/psychological-processes-in-chronic-embitterment-the-potential-contribution-of-rumination
#6
Joanne M Dunn, Tom Sensky
OBJECTIVE: Chronic embitterment has received considerable attention in terms of its presentation and epidemiology, but there has been relatively little focus on its psychology. The present study aimed to test the hypothesis that embitterment is positively correlated with rumination, and that this effect is influenced by positive beliefs about rumination. METHOD: A convenience sample (N = 79) of staff of a health care facility attending its occupational health service completed questionnaires assessing chronic embitterment, work-related rumination (distinguishing affective rumination and problem solving pondering), positive beliefs about rumination, and depression...
January 2018: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29314557/assessment-of-cognitive-functions-in-bipolar-i-disorder-a-1-year-naturalistic-follow-up-study
#7
Rajesh Sagar, Anamika Sahu, Raman Deep Pattanayak, Biswadip Chatterjee
OBJECTIVE: Available findings from cross-sectional studies have demonstrated cognitive impairments in bipolar I disorder (BD-I) during various phases of illness. However, very little is known about the longitudinal course of these cognitive impairments. The purpose of the study was to explore the longitudinal pattern of changes in cognitive functioning of BD-I patients. METHODS: A total of 129 BD-I subjects (manic, depressed and euthymic groups) and 49 healthy controls were recruited using predefined selection criteria...
January 4, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29313171/gender-effect-on-well-being-of-the-oldest-old-a-survey-of-nonagenarians-living-in-tuscany-the-mugello-study
#8
Luca Padua, Patrizio Pasqualetti, Daniele Coraci, Isabella Imbimbo, Alessandro Giordani, Claudia Loreti, Camillo Marra, Raffaello Molino-Lova, Guido Pasquini, Ilaria Simonelli, Federica Vannetti, Claudio Macchi
The population of industrialized nations is progressively aging, with Italy having one of the most elderly populations in the world. Natural aging may be associated with physical and cognitive impairments, often straining public resources. The present study aims to investigate the influence of gender on wellness of the nonagenarians. We evaluated quality of life among nonagenarians living in the Mugello area, an Italian location with a large population of individuals > 90 years, using the Health Survey Scoring SF-12...
January 8, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29303706/fatigue-in-systemic-sclerosis-a-systematic-review
#9
REVIEW
Fabio Basta, Antonella Afeltra, Domenico Paolo Emanuele Margiotta
OBJECTIVES: To systematically review fatigue in systemic sclerosis (SSc) in terms of prevalence, features, correlates, predictors and management. METHODS: We performed a literature search in PubMed (Medline), EBSCO and COCHRANE databases up to June 2017 selecting articles regarding fatigue in SSc. The articles finally selected fulfilled the following eligibility criteria: written in English, referred to fatigue in SSc, reporting original data, including validated questionnaires measuring fatigue...
December 15, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29301544/tai-chi-chuan-in-postsurgical-non-small-cell-lung-cancer-patients-study-protocol-for-a-randomized-controlled-trial
#10
Hong Pan, Yingxia Pei, Bingxue Li, Yi Wang, Jie Liu, Hongsheng Lin
BACKGROUND: Impairment of exercise capacity remains a common adverse effect of non-small cell lung cancer (NSCLC) survivors after surgery. Previous research has suggested that Tai Chi Chuan (TCC) offers an exercise capacity benefit in several types of cancers. This is a randomized trial to investigate the efficacy and safety of TCC in postoperative NSCLC patients over an observation period of 3 months and a 9-month follow-up. METHODS/DESIGN: Using a prospective, one center and randomized design, 120 subjects with histologically confirmed stage I-IIIA NSCLC following complete surgical resection will potentially be eligible for this trial...
January 4, 2018: Trials
https://www.readbyqxmd.com/read/29243873/a-comprehensive-review-of-genetic-and-epigenetic-mechanisms-that-regulate-bdnf-expression-and-function-with-relevance-to-major-depressive-disorder
#11
REVIEW
Benjamin Hing, Leela Sathyaputri, James B Potash
Major depressive disorder (MDD) is a mood disorder that affects behavior and impairs cognition. A gene potentially important to this disorder is the brain derived neurotrophic factor (BDNF) as it is involved in processes controlling neuroplasticity. Various mechanisms exist to regulate BDNF's expression level, subcellular localization, and sorting to appropriate secretory pathways. Alterations to these processes by genetic factors and negative stressors can dysregulate its expression, with possible implications for MDD...
December 15, 2017: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/29234305/functional-components-of-cognitive-impairment-in-multiple-sclerosis-a-cross-sectional-investigation
#12
Jordi A Matias-Guiu, Ana Cortés-Martínez, María Valles-Salgado, Celia Oreja-Guevara, Vanesa Pytel, Paloma Montero, Teresa Moreno-Ramos, Jorge Matias-Guiu
Background: Cognitive impairment is frequent and disabling in multiple sclerosis (MS). Changes in information processing speed constitute the most important cognitive deficit in MS. However, given the clinical and topographical variability of the disease, cognitive impairment may vary greatly and appear in other forms in addition to slower information processing speed. Our aim was to determine the frequency of cognitive impairment, the principal cognitive domains, and components involved in MS and to identify factors associated with presence of cognitive impairment in these patients in a large series of patients...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29228516/refining-prediction-in-treatment-resistant-depression-results-of-machine-learning-analyses-in-the-trd-iii-sample
#13
Alexander Kautzky, Markus Dold, Lucie Bartova, Marie Spies, Thomas Vanicek, Daniel Souery, Stuart Montgomery, Julien Mendlewicz, Joseph Zohar, Chiara Fabbri, Alessandro Serretti, Rupert Lanzenberger, Siegfried Kasper
OBJECTIVE: The study objective was to generate a prediction model for treatment-resistant depression (TRD) using machine learning featuring a large set of 47 clinical and sociodemographic predictors of treatment outcome. METHOD: 552 Patients diagnosed with major depressive disorder (MDD) according to DSM-IV criteria were enrolled between 2011 and 2016. TRD was defined as failure to reach response to antidepressant treatment, characterized by a Montgomery-Asberg Depression Rating Scale (MADRS) score below 22 after at least 2 antidepressant trials of adequate length and dosage were administered...
December 5, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29228293/providing-mental-health-care-for-the-complex-older-veteran-implications-for-social-work-practice
#14
Gayle Clark, Susan Rouse, Heather Spangler, Jennifer Moye
Mental health conditions are underdiagnosed and undertreated in older veterans, as with all older adults. Social workers bring an important perspective to the interdisciplinary team for the care of older veterans with mental health conditions. In this study authors assessed 50 older veterans referred for mental health treatment (mean age = 74.52 years, SD = 6.48) with standardized measures of depression, posttraumatic stress disorder (PTSD), and cognitive impairment. At initial assessment, 24 percent had moderate depression, 30 percent had PTSD, and 62 percent (n = 31) had (mostly mild) cognitive impairment based on cut scores...
December 8, 2017: Health & Social Work
https://www.readbyqxmd.com/read/29228200/ect-has-greater-efficacy-than-fluoxetine-in-alleviating-the-burden-of-illness-for-patients-with-major-depressive-disorder-a-taiwanese-pooled-analysis
#15
Ching-Hua Lin, Chun-Jen Huang, Cheng-Chung Chen
Background: The burden of major depressive disorder (MDD) includes suffering due to symptom severity, functional impairment, and quality of life (QOL) deficits. The aim of this study was to compare the differences between ECT and pharmacotherapy in reducing such burdens. Methods: This was a pooled analysis study including two open-label trials for MDD inpatients receiving either standard bitemporal and modified ECT with a maximum of 12 sessions, or 20 mg/d of fluoxetine for 6 weeks...
December 8, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29224581/executive-function-and-other-cognitive-deficits-are-distal-risk-factors-of-generalized-anxiety-disorder-9-years-later
#16
Nur Hani Zainal, Michelle G Newman
OBJECTIVE: The cognitive model (Hirsch & Mathews, 2012) and attentional control theory (Eysenck & Derakshan, 2011) postulate that compromised executive function (EF) and other cognitive constructs are negatively linked to increased excessive and uncontrollable worry, the core symptom of generalized anxiety disorder (GAD). However, the prospective link between neuropsychological constructs and GAD are not well understood. METHODS: A nationally representative sample of 2605 community-dwelling adults whose average age was 55...
December 11, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29223069/neuropsychological-and-clinical-heterogeneity-of-cognitive-impairment-in-patients-with-multiple-system-atrophy
#17
Lorena Broseghini Barcelos, Flávia Saad, Carla Giacominelli, Roberta Arb Saba, Patrícia Maria de Carvalho Aguiar, Sonia Maria Azevedo Silva, Vanderci Borges, Paulo Henrique Ferreira Bertolucci, Henrique Ballalai Ferraz
OBJECTIVE: We evaluated neuropsychological tests to compare cognitive impairment between two types of multiple system atrophy: predominant parkinsonism (MSA-P) and predominant cerebellar ataxia (MSA-C). PATIENTS AND METHODS: This cross-sectional study included 14 patients diagnosed with MSA: four with MSA-C and ten with MSA-P. Presence of motor symptoms was determined by using the Unified Rating MSA Scale (URMSAS). Non-motor symptoms were evaluated by the Short Form Health Survey (SF-36), Scales for Outcomes in Parkinson's disease Autonomic (SCOPA-AUT), Hospital Anxiety and Depression Scale (HADS), and Beck Depression Inventory (BDI)...
October 31, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29213522/memory-specificity-training-can-improve-working-and-prospective-memory-in-amnestic-mild-cognitive-impairment
#18
Golita Emsaki, Hamid Taher NeshatDoost, Mahgol Tavakoli, Majid Barekatain
Amnestic Mild Cognitive Impairment (MCI) is one of the cognitive profiles of aging. OBJECTIVE: In this study, Memory Specificity Training (MEST) was used as cognitive training in patients with amnestic MCI to understand the effectiveness of the intervention on memory dimensions. METHODS: Twenty patients that met the criteria for amnestic MCI were selected and randomly assigned to experimental (n=10) or control (n=10) groups. The experimental group received five sessions of training on memory specificity while the participants in the control group took part in two general placebo sessions...
July 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29213506/symptoms-of-depression-in-patients-with-mild-cognitive-impairment-in-parkinson-s-disease
#19
Ana Lara Soares Blum Malak, Luiz Felipe Vasconcellos, João Santos Pereira, Denise Vieira Greca, Manuela Cruz, Heloisa Veiga Dias Alves, Mariana Sptiz, Helenice Charchat-Fichman
Objective: To investigate the most frequent depressive symptoms and their association with cognition in Parkinson's disease (PD) patients with mild cognitive impairment (MCI). Methods: 48 patients with PD and 44 controls (CG), aged between 50 and 80 years and with at least 4 years of formal education, all with MCI and none diagnosed with depression, were assessed. Patients and controls were matched for age, education, and Mini-Mental State Examination (MMSE) score...
April 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29212489/health-care-utilization-of-patients-with-chronic-back-pain-before-and-after-rehabilitation
#20
Magdalena Görge, Jeanette Ziehm, Erik Farin
BACKGROUND: Patients with chronic back pain show an increased use of health-care services leading to high direct costs. Multidisciplinary rehabilitation reduces pain intensity, depression, disability and work inability. The study aims to investigate whether health-care utilization in patients with chronic back pain is lower after rehabilitation than before rehabilitation and if, in addition to sociodemographic, medical and psychological characteristics, changes in these characteristics immediately after rehabilitation can predict health-care utilization...
December 6, 2017: BMC Health Services Research
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