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https://www.readbyqxmd.com/read/28822267/a-similar-pro-anti-inflammatory-cytokine-balance-is-present-in-the-airways-of-competitive-athletes-and-non-exercising-asthmatics
#1
Marcin Kurowski, Janusz Jurczyk, Agnieszka Olszewska-Ziąber, Marzanna Jarzębska, Hubert Krysztofiak, Marek L Kowalski
PURPOSE: Intensive exercise modifies airway inflammation and infection susceptibility. We aimed to determine the effect of exercise on pro- and anti-inflammatory cytokine (TNF-α, IL-1ra, IL-10) and innate immunity protein (HSPA1, sCD14) levels in exhaled breath condensate (EBC) and nasal secretions of competitive athletes, non-exercising asthmatics and healthy controls (HC). MATERIAL AND METHODS: The study group consisted of 15 competitive athletes (five speed skaters and ten swimmers) aged 15-25...
August 16, 2017: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28820651/starting-and-stopping-kinetics-of-a-rear-mounted-power-assist-for-manual-wheelchairs
#2
Stephanie Wong, Ben Mortenson, Bonita Sawatzky
A rear mounted, powered, drive wheel has been developed to assist with mobility for manual wheelchairs in indoor and outdoor modes. To start the wheel, users must initiate handrim propulsion with sufficient force to trigger the motor. To stop the indoor mode, users must apply a braking force through the handrims exceeding the device's deceleration threshold. The objectives of this study were to compare 1) the minimum force required to start a wheelchair with and without the wheel, and 2) the distances and forces needed to stop a wheelchair at different treadmill speeds (3...
August 18, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28819811/circulating-extracellular-vesicles-in-the-aging-process-impact-of-aerobic-exercise
#3
Karine Bertoldi, Laura Reck Cechinel, Bruna Schallenberger, Giana Blume Corssac, Samuel Davies, Irene Clemes Külkamp Guerreiro, Adriane Belló-Klein, Alex Sander R Araujo, Ionara Rodrigues Siqueira
Our aim was to investigate transitory and delayed exercise effects on serum extracellular vesicles (EVs) in aging process. Male Wistar rats of 3-, 21-, and 26-month old were allocated into exercised and sedentary groups. The exercise protocol consisted in a daily moderate treadmill exercise (20 min daily during 2 weeks). Trunk blood was collected 1 and 18 h after the last exercise session, and circulating EVs were obtained. CD63 levels and acetylcholinesterase (AChE) activity were used as markers of exosome, a subtype of EVs...
August 17, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28819266/amalaki-rasayana-a-traditional-indian-drug-enhances-cardiac-mitochondrial-and-contractile-functions-and-improves-cardiac-function-in-rats-with-hypertrophy
#4
Vikas Kumar, Kumar A Aneesh, K Kshemada, Kumar G S Ajith, Raj S S Binil, Neha Deora, G Sanjay, A Jaleel, T S Muraleedharan, E M Anandan, R S Mony, M S Valiathan, Kumar T R Santhosh, C C Kartha
We evaluated the cardioprotective effect of Amalaki Rasayana (AR), a rejuvenating Ayurvedic drug prepared from Phyllanthus emblica fruits in the reversal of remodeling changes in pressure overload left ventricular cardiac hypertrophy (LVH) and age-associated cardiac dysfunction in male Wistar rats. Six groups (aging groups) of 3 months old animals were given either AR or ghee and honey (GH) orally; seventh group was untreated. Ascending aorta was constricted using titanium clips in 3 months old rats (N = 24; AC groups) and after 6 months, AR or GH was given for further 12 months to two groups; one group was untreated...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819005/blood-pressure-and-leg-deoxygenation-are-exaggerated-during-treadmill-walking-in-patients-with-peripheral-artery-disease
#5
Amanda J Miller, J Carter Luck, Danielle Jin-Kwang Kim, Urs A Leuenberger, David N Proctor, Lawrence I Sinoway, Matthew D Muller
The purpose of this study was to investigate blood pressure (BP) and leg skeletal muscle oxygen saturation (SmO2) during treadmill walking in patients with peripheral artery disease (PAD) and healthy subjects. Eight PAD patients (66 ± 3 years, 1 female) and eight healthy subjects (65 ± 2 years, 1 female) walked on a treadmill at 2 miles/hour. The incline increased by 2% every 2 minutes from 0% to 15% or until maximal discomfort. BP was measured every 2 min with an auscultatory cuff. Heart rate (HR) was recorded continuously with an electrocardiogram...
August 17, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28818819/quantifying-human-movement-using-the-movn-smartphone-app-validation-and-field-study
#6
Ralph Maddison, Luke Gemming, Javier Monedero, Linda Bolger, Sarahjane Belton, Johann Issartel, Samantha Marsh, Artur Direito, Madeleine Solenhill, Jinfeng Zhao, Daniel John Exeter, Harshvardhan Vathsangam, Jonathan Charles Rawstorn
BACKGROUND: The use of embedded smartphone sensors offers opportunities to measure physical activity (PA) and human movement. Big data-which includes billions of digital traces-offers scientists a new lens to examine PA in fine-grained detail and allows us to track people's geocoded movement patterns to determine their interaction with the environment. OBJECTIVE: The objective of this study was to examine the validity of the Movn smartphone app (Moving Analytics) for collecting PA and human movement data...
August 17, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28818578/can-exercise-training-counteract-doxorubicin-induced-oxidative-damage-of-testis-proteome
#7
José Magalhães, António Ascensão, Ana I Padrão, Inês M Aleixo, Estela Santos-Alves, Sílvia Rocha-Rodrigues, André Ferreira, Luis Korrodi-Gregório, Rui Vitorino, Rita Ferreira, Margarida Fardilha
The use of the chemotherapeutic drug doxorubicin (DOX) is limited by its toxicity in several organs such as testes. So, we analyzed the effect of endurance treadmill exercise training (EX) performed before sub-chronic DOX treatment on sperm count and motility, testes markers of oxidative damage and apoptosis. Tissue profiling of proteins more susceptible to oxidation was made to identify the molecular pathways regulated by oxidative modifications, as nitration and carbonylation. Twenty-four adult male rats were divided into four groups (n=6/group): sedentary saline (SED+SAL), sedentary sub-chronically injected with DOX (2mg-kg-1 per week, during 7 weeks; SED+DOX), 12 weeks trained saline (EX+SAL) and trained treated with DOX (EX+DOX)...
August 14, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28818411/long-term-supplementation-with-egcg-and-beta-alanine-decreases-mortality-but-does-not-affect-cognitive-or-muscle-function-in-aged-mice
#8
Brandt D Pence, Tushar K Bhattacharya, Pul Park, Jennifer L Rytych, Jacob M Allen, Yi Sun, Robert H McCusker, Keith W Kelley, Rodney W Johnson, Justin S Rhodes, Jeffrey A Woods
We have previously shown that 6weeks of a diet containing epigallocatechin gallate (EGCG) and beta-alanine (B-ALA) was not effective in improving either cognitive or muscle function in aged (18month) mice (Gibbons et al. Behav Brain Res 2014). However, diet reduced oxidative stress in the brain, and previous studies using longer-term interventions have documented beneficial effects in cognitive, but not muscle, function. Therefore, we investigated the effect of 6months of feeding on measures of cognitive and muscle function in mice...
August 14, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28818143/locomotion-strategy-and-magnitude-of-ground-reaction-forces-during-treadmill-training-on-iss
#9
Elena Fomina, Alexandra Savinkina
INTRODUCTION: Creation of the cosmonaut in-flight physical training process is currently based on the leading role of support afferents in the development of hypogravity changes in the motor system. We assume that the strength of support afferents is related to the magnitude of the ground reaction forces (GRF). For this purpose it was necessary to compare the GRF magnitude on the Russian BD-2 treadmill for different locomotion types (walking and running), modes (active and passive), and subjects...
September 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28818107/patellofemoral-kinematics-in-dogs-with-cranial-cruciate-ligament-insufficiency-an-in-vivo-fluoroscopic-analysis-during-walking
#10
Stanley E Kim, Geoffrey J Zann, Selena Tinga, Erica J Moore, Antonio Pozzi, Scott A Banks
BACKGROUND: Complete rupture of the cranial cruciate ligament (CrCL) in dogs causes profound disturbance to stifle joint biomechanics. The objective of this study was to characterize the effects of cranial cruciate ligament (CrCL) insufficiency on patellofemoral (PF) kinematics in dogs during walking. Ten client-owned dogs (20-40 kg) with natural unilateral complete CrCL rupture were included. Dogs underwent computed tomographic scans to create digital bone-models of the patella and femur...
August 17, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28817828/fall-prone-older-people-s-attitudes-towards-the-use-of-virtual-reality-technology-for-fall-prevention
#11
Kim Dockx, Lisa Alcock, Esther Bekkers, Pieter Ginis, Miriam Reelick, Elisa Pelosin, Giovanna Lagravinese, Jeffrey M Hausdorff, Anat Mirelman, Lynn Rochester, Alice Nieuwboer
BACKGROUND: Virtual reality (VR) technology is a relatively new rehabilitation tool that can deliver a combination of cognitive and motor training for fall prevention. The attitudes of older people to such training are currently unclear. OBJECTIVE: This study aimed to investigate: (1) the attitudes of fall-prone older people towards fall prevention exercise with and without VR; (2) attitudinal changes after intervention with and without VR; and (3) user satisfaction following fall prevention exercise with and without VR...
August 18, 2017: Gerontology
https://www.readbyqxmd.com/read/28815562/treadmill-training-and-body-weight-support-for-walking-after-stroke
#12
REVIEW
Jan Mehrholz, Simone Thomas, Bernhard Elsner
BACKGROUND: Treadmill training, with or without body weight support using a harness, is used in rehabilitation and might help to improve walking after stroke. This is an update of the Cochrane review first published in 2003 and updated in 2005 and 2014. OBJECTIVES: To determine if treadmill training and body weight support, individually or in combination, improve walking ability, quality of life, activities of daily living, dependency or death, and institutionalisation or death, compared with other physiotherapy gait-training interventions after stroke...
August 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28814168/deterioration-of-heart-rate-recovery-index-in-patients-after-carotid-artery-stenting
#13
Emrah Aytac, Murat Gonen, Orhan Dogdu, Mehmet Balin
Objective Although carotid artery stenting (CAS) is an effective treatment for severe carotid stenosis, it has been associated with alterations in autonomic functions long term after the procedure. Patients with CAS have been reported to have autonomic nervous system (ANS) dysfunction. This study aimed to evaluate heart rate recovery (HRR) indices and exercise test parameters after CAS. Methods Patients (10 male, 11 female) suitable for CAS, without a history of hypertension, diabetes mellitus, severe coronary artery or valvular heart disease, were enrolled in our study...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28814056/design-of-a-lightweight-tethered-torque-controlled-knee-exoskeleton
#14
Kirby Ann Witte, Andreas M Fatschel, Steven H Collins
Lower-limb exoskeletons show promise for improving gait rehabilitation for those with chronic gait abnormalities due to injury, stroke or other illness. We designed and built a tethered knee exoskeleton with a strong lightweight frame and comfortable, four-point contact with the leg. The device is structurally compliant in select directions, instrumented to measure joint angle and applied torque, and is lightweight (0.76 kg). The exoskeleton is actuated by two off-board motors. Closed loop torque control is achieved using classical proportional feedback control with damping injection in conjunction with iterative learning...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28814046/adaptive-control-of-an-actuated-ankle-foot-orthosis
#15
Victor Arnez-Paniagua, Hala Rifai, Yacine Amirat, Samer Mohammed
This paper deals with the control of an active ankle foot orthosis (AAFO) to assist the gait of paretic patients. The AAFO system is driven by both, the residual human torque delivered by the muscles spanning the ankle joint and the AAFO's actuator's torque. A projection-based model reference adaptive control is proposed to assist dorsiflexion and plantar-flexion of the ankle joint during daily living walking activities. Unlike most classical model-based controllers, the proposed one does not require any prior estimation of the system's (foot-AAFO) parameters...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813869/effects-of-assistance-timing-on-metabolic-cost-assistance-power-and-gait-parameters-for-a-hip-type-exoskeleton
#16
Jusuk Lee, Keehong Seo, Bokman Lim, Junwon Jang, Kyungrock Kim, Hyundo Choi
There are many important factors in developing an exoskeleton for assisting human locomotion. For example, the weight should be sufficiently light, the assist torque should be high enough to assist joint motion, and the assistance timing should be just right. Understanding how these design parameters affect overall performance of a complex human-machine system is critical for the development of these types of systems. The present study introduces an assistance timing controller that regulates assistance timing such that peak joint velocity and peak assistance power are offset by a reference value for our hip-type exoskeleton...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813868/relationship-between-assistive-torque-and-knee-biomechanics-during-exoskeleton-walking-in-individuals-with-crouch-gait
#17
Zachary F Lerner, Diane L Damiano, Thomas C Bulea
Crouch or "flexed knee" gait is a pathological gait pattern affecting many individuals with cerebral palsy. One proposed method to alleviate crouch is to provide robotic assistance to knee extension during walking. The purpose of this study was to evaluate how the magnitude of knee extensor torque affects knee kinematics, kinetics, and muscle activity. Motion capture, ground reaction force and electromyography data were collected while four participants with crouch gait from cerebral palsy walked with assistance from a novel robotic exoskeleton on an instrumented treadmill...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813867/therapeutic-effects-of-anti-gravity-treadmill-alterg-training-on-reflex-hyper-excitability-corticospinal-tract-activities-and-muscle-stiffness-in-children-with-cerebral-palsy
#18
Sh Parvin, A Taghiloo, A Irani, M Mehdi Mirbagheri
We aimed to study therapeutic effects of antigravity treadmill (AlterG) training on reflex hyper-excitability, muscle stiffness, and corticospinal tract (CST) function in children with spastic hemiplegic cerebral palsy (CP). Three children received AlterG training 3 days per week for 8 weeks as experimental group. Each session lasted 45 minutes. One child as control group received typical occupational therapy for the same amount of time. We evaluated hyper-excitability of lower limb muscles by H-reflex response...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813849/effects-of-partial-body-weight-support-and-functional-electrical-stimulation-on-gait-characteristics-during-treadmill-locomotion-pros-and-cons-of-saddle-seat-type-body-weight-support
#19
Natsumi Kataoka, Hiroaki Hirai, Taya Hamilton, Fumiaki Yoshikawa, Akira Kuroiwa, Yuma Nagakawa, Eichi Watanabe, Yudai Ninomaru, Yuri Saeki, Mitsunori Uemura, Fumio Miyazaki, Hiroshi Nakata, Tomoki Nishi, Hiroaki Naritomi, Hermano Igo Krebs
Robotic therapy for rehabilitation of the lower extremity is currently in its early stage of development. Aiming at exploring an efficacious intervention for gait rehabilitation, we investigate the characteristics of an end-effector gait-training device that combines saddle-seat-type body-weight-supported treadmill training with functional electrical stimulation (FES). This is a task-oriented approach to restoring voluntary control of locomotion in patients with neuromuscular diseases. We evaluate the differences between walking with saddle-seat-type support and with harness-type support, in terms of personal preference, the preferred walking speed, profiles of kinematics and ground reaction force, and the effectiveness of FES...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813842/using-wearable-physiological-sensors-to-predict-energy-expenditure
#20
Kimberly A Ingraham, Daniel P Ferris, C David Remy
Lower-limb assistive robotic devices are often evaluated by measuring a reduction in the user's energy cost. Using indirect calorimetry to estimate energy cost is poorly suited for real-time estimation and long-term collection. The goal of this study was to use data from wearable sensors to predict energy cost with better temporal resolution and less variability than breath measurements. We collected physiological data (heart rate, electrodermal activity, skin temperature) and mechanical data (EMG, accelerometry) from three healthy subjects walking on a treadmill at various speeds on level ground, inclined, and backwards...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
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