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https://www.readbyqxmd.com/read/28445855/speed-dependent-effects-of-laterally-wedged-insoles-on-gait-biomechanics-in-healthy-subjects
#1
Felix Kluge, Sebastian Krinner, Matthias Lochmann, Bjoern M Eskofier
Laterally wedged insoles have been shown to be effective for the reduction of the knee adduction moment and other biomechanical variables that are associated with the pathogenesis of knee osteoarthritis. However, inconclusive results such as adverse effects in individual subjects or even no group-wise wedge effects have been presented in different studies and it has been suggested to identify variables that potentially confound the wedge effect. The main objective of this study was the investigation of interaction effects of lateral wedges with walking speed, as different self-selected speeds have mainly been used in previous studies...
April 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28441562/bacterial-division-ftsz-treadmills-to-build-a-beautiful-wall
#2
Kara M Schoenemann, William Margolin
The tubulin-like FtsZ protein polymerizes into a contractile ring structure required for cytokinesis in most bacteria. Two new studies report that FtsZ polymers move around the ring by treadmilling, which guides and regulates the inward growth of the septal wall.
April 24, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28441054/biomechanical-and-histologic-evaluation-of-the-effects-of-underwater-treadmill-exercise-on-horses-with-experimentally-induced-osteoarthritis-of-the-middle-carpal-joint
#3
Melissa R King, Kevin K Haussler, Chris E Kawcak, C Wayne McIlwraith, Raoul F Reiser, David D Frisbie, Natasha M Werpy
OBJECTIVE To evaluate the effects of exercise in an underwater treadmill (UWT) on forelimb biomechanics and articular histologic outcomes in horses with experimentally induced osteoarthritis of the middle carpal joint. ANIMALS 16 horses. PROCEDURES An osteochondral fragment was induced arthroscopically (day 0) in 1 middle carpal joint of each horse. Beginning on day 15, horses were assigned to exercise in a UWT or in the UWT without water (simulating controlled hand walking) at the same speed, frequency, and duration...
May 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28440910/subacute-pyridostigmine-exposure-increases-heart-rate-recovery-and-cardiac-parasympathetic-tone-in-rats
#4
Manushree Bharadwaj, Carey Pope, Michael Davis, Stuart Katz, Christian Cook, Lara Maxwell
Heart rate recovery (HRR) describes the rapid deceleration of heart rate after strenuous exercise and is an indicator of parasympathetic tone. A reduction in parasympathetic tone occurs in patients with congestive heart failure, resulting in prolonged HRR. Acetylcholinesterase inhibitors, such as pyridostigmine, can enhance parasympathetic tone by increasing cholinergic input to the heart. The objective of this study was to develop a rodent model of HRR to test the hypothesis that subacute pyridostigmine administration decreases cholinesterase activity and accelerates HRR in rats...
April 25, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28440411/effects-of-long%C3%A2-term-post%C3%A2-ischemic-treadmill-exercise-on-gliosis-in-the-aged-gerbil-hippocampus-induced-by-transient-cerebral-ischemia
#5
Ji Hyeon Ahn, Myoung Cheol Shin, Joon Ha Park, In Hye Kim, Jeong-Hwi Cho, Tae-Kyeong Lee, Jae-Chul Lee, Bai Hui Chen, Bich Na Shin, Hyun-Jin Tae, Jinseu Park, Soo Young Choi, Yun Lyul Lee, Dae Won Kim, Yang Hee Kim, Moo-Ho Won, Jun Hwi Cho
Therapeutic exercise is an integral component of the rehabilitation of patients who have suffered a stroke. The objective of the present study was to use immunohistochemistry to investigate the effects of post‑ischemic exercise on neuronal damage or death and gliosis in the aged gerbil hippocampus following transient cerebral ischemia. Aged gerbils (male; age, 22‑24 months) underwent ischemia and were subjected to treadmill exercise for 1 or 4 weeks. Neuronal death was detected in the stratum pyramidale of the hippocampal CA1 region and in the polymorphic layer of the dentate gyrus using cresyl violet and Fluoro‑Jade B histofluorescence staining...
April 19, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28439212/effect-of-thyme-extract-supplementation-on-lipid-peroxidation-antioxidant-capacity-pgc-1%C3%AE-content-and-endurance-exercise-performance-in-rats
#6
Mostafa Khani, Pezhman Motamedi, Mohammad Reza Dehkhoda, Saeed Dabagh Nikukheslat, Pouran Karimi
BACKGROUND: Athletes have a large extent of oxidant agent production. In the current study, we aimed to determine the influence of thyme extract on the endurance exercise performance, mitochondrial biogenesis, and antioxidant status in rats. METHODS: Twenty male Wistar rats were randomly divided into two groups receiving either normal drinking water (non-supplemented group, n = 10) or thyme extract, 400 mg/kg, (supplemented group, n = 10). Rats in both groups were subjected to endurance treadmill training (27 m/min, 10% grade, 60 min, and 5 days/week for 8 weeks)...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28438166/adjacent-regenerative-peripheral-nerve-interfaces-produce-phase-antagonist-signals-during-voluntary-walking-in-rats
#7
Daniel Ursu, Andrej Nedic, Melanie Urbanchek, Paul Cederna, R Brent Gillespie
BACKGROUND: Regenerative Peripheral Nerve Interfaces (RPNIs) are neurotized muscle grafts intended to produce electromyographic signals suitable for motorized prosthesis control. Two RPNIs producing independent agonist/antagonist signals are required for each control axis; however, it is unknown whether signals from adjacent RPNIs are independent. The purpose of this work was to determine signaling characteristics from two adjacent RPNIs, the first neurotized by a foot dorsi-flexor nerve and the second neurotized by a foot plantar-flexor nerve in a rodent model...
April 24, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28437756/local-dynamic-stability-and-gait-variability-during-attentional-tasks-in-young-adults
#8
Rina Márcia Magnani, Georgia Cristina Lehnen, Fábio Barbosa Rodrigues, Gustavo Souto de Sá E Souza, Adriano de Oliveira Andrade, Marcus Fraga Vieira
Cell phone use while walking may be a cognitive distraction and reduce visual and motor attention. Thus, the aim of this study was to verify the effects of attentional dual-tasks while using a cell phone in different conditions. Stability, regularity, and linear variability of trunk kinematics, and gait spatiotemporal parameters in young adults were measured. Twenty young subjects of both genders were asked to walk on a treadmill for 4min under the following conditions: (a) looking forward at a fixed target 2...
April 18, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28436878/biofeedback-for-gait-retraining-based-on-real-time-estimation-of-tibiofemoral-joint-contact-forces
#9
Claudio Pizzolato, Monica Reggiani, David J Saxby, Elena Ceseracciu, Luca Modenese, David G Lloyd
Biofeedback assisted rehabilitation and intervention technologies have the potential to modify clinically relevant biomechanics. Gait retraining has been used to reduce the knee adduction moment, a surrogate of medial tibiofemoral joint loading often used in knee osteoarthritis research. In this study we present an electromyogram-driven neuromusculoskeletal model of the lower-limb to estimate, in real-time, the tibiofemoral joint loads. The model included 34 musculotendon units spanning the hip, knee, and ankle joints...
April 18, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28435743/effects-of-overground-locomotor-training-on-the-ventilatory-response-to-volitional-treadmill-walking-in-individuals-with-incomplete-spinal-cord-injury-a-pilot-study
#10
Gino S Panza, Andrew A Guccione, Lisa M Chin, Jared M Gollie, Jeffery E Herrick, John P Collins
INTRODUCTION: Although there has been substantial emphasis on the neuromuscular and cardiovascular adaptations following rehabilitation, pulmonary adaptations in individuals with incomplete SCI (iSCI) in response to locomotor training have been less frequently studied. In healthy individuals, effective transition from rest to work is accomplished by a hyperpneic response, which exhibits an exponential curve with three phases. However, the degree to which our current understanding of exercise hyperpnea can be applied to individuals with iSCI is unknown...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28433868/effects-of-attentional-focus-on-walking-stability-in-elderly
#11
Jonathan L A de Melker Worms, John F Stins, Erwin E H van Wegen, Sabine M P Verschueren, Peter J Beek, Ian D Loram
INTRODUCTION: Balance performance in the elderly is related to psychological factors such as attentional focus. We investigated the effects of internal vs. external focus of attention and fall history on walking stability in healthy older adults. METHOD: Walking stability of twenty-eight healthy older adults was assessed by applying random unilateral decelerations on a split-belt treadmill and analysing the resulting balance recovery movements. The internal focus instruction was: concentrate on the movement of your legs, whereas the external focus instruction was: concentrate on the movement of the treadmill...
April 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28433867/validity-and-repeatability-of-inertial-measurement-units-for-measuring-gait-parameters
#12
Edward P Washabaugh, Tarun Kalyanaraman, Peter G Adamczyk, Edward S Claflin, Chandramouli Krishnan
Inertial measurement units (IMUs) are small wearable sensors that have tremendous potential to be applied to clinical gait analysis. They allow objective evaluation of gait and movement disorders outside the clinic and research laboratory, and permit evaluation on large numbers of steps. However, repeatability and validity data of these systems are sparse for gait metrics. The purpose of this study was to determine the validity and between-day repeatability of spatiotemporal metrics (gait speed, stance percent, swing percent, gait cycle time, stride length, cadence, and step duration) as measured with the APDM Opal IMUs and Mobility Lab system...
April 12, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28431747/effects-of-vibration-training-in-reducing-risk-of-slip-related-falls-among-young-adults-with-obesity
#13
Feng Yang, Jose Munoz, Long-Zhu Han, Fei Yang
This study examined the effects of controlled whole-body vibration training on reducing risk of slip-related falls in people with obesity. Twenty-three young adults with obesity were randomly assigned into either the vibration or placebo group. The vibration and placebo groups respectively received 6-week vibration and placebo training on a side-alternating vibration platform. Before and after the training, the isometric knee extensors strength capacity was measured for the two groups. Both groups were also exposed to a standardized slip induced by a treadmill during gait prior to and following the training...
April 9, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28431220/contribution-of-ankle-foot-orthosis-moment-in-regulating-ankle-and-knee-motions-during-gait-in-individuals-post-stroke
#14
Toshiki Kobayashi, Michael S Orendurff, Madeline L Singer, Fan Gao, K Bo Foreman
BACKGROUND: Ankle-foot orthosis moment resisting plantarflexion has systematic effects on ankle and knee joint motion in individuals post-stroke. However, it is not known how much ankle-foot orthosis moment is generated to regulate their motion. The aim of this study was to quantify the contribution of an articulated ankle-foot orthosis moment to regulate ankle and knee joint motion during gait in individuals post-stroke. METHODS: Gait data were collected from 10 individuals post-stroke using a Bertec split-belt instrumented treadmill and a Vicon 3-dimensional motion analysis system...
April 8, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28430704/functional-effects-of-treadmill-based-gait-training-at-faster-speeds-in-stroke-survivors-a-prospective-single-group-study
#15
Roghayeh Mohammadi, Navid Ershad, Marziyeh Rezayinejad, Elham Fatemi, Chetan P Phadke
To examine the functional effects of walking retraining at faster than self-selected speed (SSS). Ten individuals with chronic stroke participated in a 4-week training over a treadmill at walking speeds 40% faster than SSS, three times per week, 30 min/session. Outcome measures assessed before, after, and 2 months after the end of intervention were the Timed Up and Go, the 6-Minute Walk, the 10-Meter Walk test, the Modified Ashworth Scale, SSS, and fastest comfortable speed. After 4 weeks of training, all outcome measures showed clinically meaningful and statistically significant improvements (P<0...
April 20, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28430546/overall-preference-of-running-shoes-can-be-predicted-by-suitable-perception-factors-using-a-multiple-regression-model
#16
Cheryl Sihui Tay, Thorsten Sterzing, Chen Yen Lim, Rui Ding, Pui Wah Kong
OBJECTIVE: This study examined (a) the strength of four individual footwear perception factors to influence the overall preference of running shoes and (b) whether these perception factors satisfied the nonmulticollinear assumption in a regression model. BACKGROUND: Running footwear must fulfill multiple functional criteria to satisfy its potential users. Footwear perception factors, such as fit and cushioning, are commonly used to guide shoe design and development, but it is unclear whether running-footwear users are able to differentiate one factor from another...
May 2017: Human Factors
https://www.readbyqxmd.com/read/28429698/coronary-microvascular-dysfunction-equivalent-to-left-main-coronary-artery-disease
#17
Cafer Panç, Mehmet Kocaağa, Onur Erdoğan, Remzi Sarıkaya, Sabahattin Umman
Coronary microvascular dysfunction, also known as cardiac syndrome X, is a clinical syndrome presenting with typical angina and evidence of myocardial ischemia in the absence of flow-limiting stenosis on coronary angiography. Of patients undergoing coronary angiography due to suspected myocardial ischemia, 50% are found to have normal or near-normal coronary arteries. Described in this case report is a patient who developed hypotension and ST segment depressions during treadmill exercise test. Left main coronary artery or multivessel disease was suspected...
April 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28429194/photobiomodulation-therapy-associated-with-treadmill-training-in-the-oxidative-stress-in-a-collagen-induced-arthritis-model
#18
Solange Almeida Dos Santos, Marcia Ataize Dos Santos Vieira, Maira Cécilia Brandão Simões, Andrey Jorge Serra, Ernesto Cesar Leal-Junior, Paulo de Tarso Camillo de Carvalho
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by chronic and systemic inflammation, which leads to the destruction of the cartilage and bone and affects tissues in multiple joints. Oxidative stress has been implicated with regards to involvement in various disease conditions, such as diabetes mellitus and neurodegenerative, respiratory, cardiovascular, and RA diseases. In vivo experimental studies using photobiomodulation therapy (PBMT) have shown positive effects in reducing lipid peroxidation and in increasing antioxidant activity...
April 21, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28428145/prior-treadmill-exercise-promotes-resilience-to-vicarious-trauma-in-rats
#19
Camila Kochi, Hesong Liu, Safiyya Zaidi, Fatin Atrooz, Phoebe Dantoin, Samina Salim
BACKGROUND: Post-traumatic stress disorder (PTSD) is a serious psychological condition, which can develop both from physically experiencing and also from witnessing traumatic events. There is evidence that physical exercise can have a positive impact on the symptoms of PTSD. Relevant to this, in our previous pre-clinical work, beneficial effects of treadmill exercise were reported on PTSD-like behaviors in a social defeat paradigm, a rat model of direct physical trauma. However, the role of exercise on vicariously acquired PTSD-like phenotype was not examined...
April 17, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28427422/differences-in-muscle-activity-and-temporal-step-parameters-between-lokomat-guided-walking-and-treadmill-walking-in-post-stroke-hemiparetic-patients-and-healthy-walkers
#20
Klaske van Kammen, Anne M Boonstra, Lucas H V van der Woude, Heleen A Reinders-Messelink, Rob den Otter
BACKGROUND: The Lokomat is a robotic exoskeleton that can be used to train gait function in hemiparetic stroke. To purposefully employ the Lokomat for training, it is important to understand (1) how Lokomat guided walking affects muscle activity following stroke and how these effects differ between patients and healthy walkers, (2) how abnormalities in the muscle activity of patients are modulated through Lokomat guided gait, and (3) how temporal step characteristics of patients were modulated during Lokomat guided walking...
April 20, 2017: Journal of Neuroengineering and Rehabilitation
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