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https://www.readbyqxmd.com/read/29239746/stepping-reaction-time-and-gait-adaptability-are-significantly-impaired-in-people-with-parkinson-s-disease-implications-for-fall-risk
#1
Maria Joana D Caetano, Stephen R Lord, Natalie E Allen, Matthew A Brodie, Jooeun Song, Serene S Paul, Colleen G Canning, Jasmine C Menant
BACKGROUND: Decline in the ability to take effective steps and to adapt gait, particularly under challenging conditions, may be important reasons why people with Parkinson's disease (PD) have an increased risk of falling. This study aimed to determine the extent of stepping and gait adaptability impairments in PD individuals as well as their associations with PD symptoms, cognitive function and previous falls. METHODS: Thirty-three older people with PD and 33 controls were assessed in choice stepping reaction time, Stroop stepping and gait adaptability tests; measurements identified as fall risk factors in older adults...
November 22, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29232576/effects-of-oxytocin-on-cortisol-reactivity-and-conflict-resolution-behaviors-among-couples-with-substance-misuse
#2
Julianne C Flanagan, Melanie S Fischer, Paul J Nietert, Sudie E Back, Megan Moran-Santa Maria, Alexandra Snead, Kathleen T Brady
Social stress, particularly in the form of dyadic conflict, is a well-established correlate of substance use disorders (SUD). The neuropeptide oxytocin can enhance prosocial behavior and mitigate addictive behaviors. These effects may be, in part, a result of oxytocin's ability to attenuate hypothalamic-pituitary-adrenal (HPA) axis dysregulation. However, only one study to date has examined the effects of oxytocin on neuroendocrine reactivity or conflict resolution behavior among couples. Participants (N = 33 couples or 66 total participants) were heterosexual couples in which one or both partners endorsed substance misuse...
December 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29224782/mfd-dynamically-regulates-transcription-via-a-release-and-catch-up-mechanism
#3
Tung T Le, Yi Yang, Chuang Tan, Margaret M Suhanovsky, Robert M Fulbright, James T Inman, Ming Li, Jaeyoon Lee, Sarah Perelman, Jeffrey W Roberts, Alexandra M Deaconescu, Michelle D Wang
The bacterial Mfd ATPase is increasingly recognized as a general transcription factor that participates in the resolution of transcription conflicts with other processes/roadblocks. This function stems from Mfd's ability to preferentially act on stalled RNA polymerases (RNAPs). However, the mechanism underlying this preference and the subsequent coordination between Mfd and RNAP have remained elusive. Here, using a novel real-time translocase assay, we unexpectedly discovered that Mfd translocates autonomously on DNA...
November 30, 2017: Cell
https://www.readbyqxmd.com/read/29216200/development-and-application-of-coupled-system-dynamics-and-game-theory-a-dynamic-water-conflict-resolution-method
#4
Mehdi Zomorodian, Sai Hin Lai, Mehran Homayounfar, Shaliza Ibrahim, Gareth Pender
Conflicts over water resources can be highly dynamic and complex due to the various factors which can affect such systems, including economic, engineering, social, hydrologic, environmental and even political, as well as the inherent uncertainty involved in many of these factors. Furthermore, the conflicting behavior, preferences and goals of stakeholders can often make such conflicts even more challenging. While many game models, both cooperative and non-cooperative, have been suggested to deal with problems over utilizing and sharing water resources, most of these are based on a static viewpoint of demand points during optimization procedures...
2017: PloS One
https://www.readbyqxmd.com/read/29212559/the-body-remembers-adolescent-conflict-struggles-predict-adult-interleukin-6-levels
#5
Joseph P Allen, Emily L Loeb, Joseph S Tan, Rachel K Narr, Bert N Uchino
Struggles managing conflict and hostility in adolescent social relationships were examined as long-term predictors of immune-mediated inflammation in adulthood that has been linked to long-term health outcomes. Circulating levels of interleukin-6 (IL-6), a marker of immune system dysfunction when chronically elevated, were assessed at age 28 in a community sample of 127 individuals followed via multiple methods and reporters from ages 13 to 28. Adult serum IL-6 levels were predicted across periods as long as 15 years by adolescents' inability to defuse peer aggression and poor peer-rated conflict resolution skills, and by independently observed romantic partner hostility in late adolescence...
December 7, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29205437/mrna-traffic-control-reviewed-n6-methyladenosine-m6-a-takes-the-driver-s-seat
#6
REVIEW
Abhirami Visvanathan, Kumaravel Somasundaram
Messenger RNA is a flexible tool box that plays a key role in the dynamic regulation of gene expression. RNA modifications variegate the message conveyed by the mRNA. Similar to DNA and histone modifications, mRNA modifications are reversible and play a key role in the regulation of molecular events. Our understanding about the landscape of RNA modifications is still rudimentary in contrast to DNA and histone modifications. The major obstacle has been the lack of sensitive detection methods since they are non-editing events...
December 4, 2017: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
https://www.readbyqxmd.com/read/29199763/domiciliary-intervention-in-psychosis-a-systematic-review
#7
Ona Gomis, Carol Palma, Núria Farriols
BACKGROUND: This theoretical study reviews the main findings and research on home-based treatment for psychosis. The principal purpose was to analyze the various types of home-based service and make recommendations for a service that would meet the needs of both first-episode and resistant patients. We compare the Early Intervention Service, which aims to reduce the range of untreated psychosis (DUP) with other types of home-care and similar interventions that have already been implemented: crisis resolution home teams (CRHTs), Open Dialogue Approach (ODA), social skills training (SST) and foster homes...
November 2017: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/29190783/satellite-imagery-based-monitoring-of-archaeological-site-damage-in-the-syrian-civil-war
#8
Jesse Casana, Elise Jakoby Laugier
Since the start of the Syrian civil war in 2011, the rich archaeological heritage of Syria and northern Iraq has faced severe threats, including looting, combat-related damage, and intentional demolition of monuments. However, the inaccessibility of the conflict zone to archaeologists or cultural heritage specialists has made it difficult to produce accurate damage assessments, impeding efforts to develop mitigation strategies and policies. This paper presents results of a project, undertaken in collaboration with the American Schools of Oriental Research (ASOR) and the US Department of State, to monitor damage to archaeological sites in Syria, northern Iraq, and southern Turkey using recent, high-resolution satellite imagery...
2017: PloS One
https://www.readbyqxmd.com/read/29186618/semi-automatized-segmentation-method-using-image-based-flow-cytometry-to-study-sperm-physiology-the-case-of-capacitation-induced-tyrosine-phosphorylation
#9
Arturo Matamoros-Volante, Ayelen Moreno-Irusta, Paulina Torres-Rodriguez, Laura Giojalas, María G Gervasi, Pablo E Visconti, Claudia L Treviño
STUDY QUESTION: Is image-based flow cytometry a useful tool to study intracellular events in human sperm such as protein tyrosine phosphorylation or signaling processes? SUMMARY ANSWER: Image-based flow cytometry is a powerful tool to study intracellular events in a relevant number of sperm cells, which enables a robust statistical analysis providing spatial resolution in terms of the specific subcellular localization of the labeling. WHAT IS KNOWN ALREADY: Sperm capacitation is required for fertilization...
November 25, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29173128/cognitive-conflict-resolution-during-psychotherapy-its-impact-on-depressive-symptoms-and-psychological-distress
#10
Clara Paz, Adrián Montesano, David Winter, Guillem Feixas
OBJECTIVE: The aim of this study was to assess the resolution of cognitive conflicts (CCs) within a randomized controlled trial testing the differential efficacy of group cognitive behavioral therapy (CBT) plus an individually tailored intervention module focused on CCs vs. group plus individual CBT, and to determine whether CC resolution was related to improvement in symptoms and psychological distress. METHODS: The data come from 104 adults meeting criteria for major depressive disorder and/or dysthymia...
November 26, 2017: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/29169068/effects-of-a-service-earning-experience-on-confidence-and-clinical-skills-in-baccalaureate-nursing-students
#11
Jennifer Saylor, Lindsey Hertsenberg, Malissa McQuillan, Ashley O'Connell, Kimberly Shoe, Christina J Calamaro
BACKGROUND: Camp programs yield positive and lasting benefits for children. Integrating a summer camp into a nurse course with a service learning design fosters learning beyond the classroom and enhances community engagement. OBJECTIVE: The purpose of this study is to describe the nursing students' experience and perceived confidence after completing a service learning nursing course. DESIGN: This is a descriptive, qualitative research study that used reflection and a perceived confidence questionnaire...
November 20, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/29167628/a-comparative-study-of-job-satisfaction-among-nurses-psychologists-psychotherapists-and-social-workers-working-in-quebec-mental-health-teams
#12
Marie-Josée Fleury, Guy Grenier, Jean-Marie Bamvita
Background: This study identified multiple socio-professional and team effectiveness variables, based on the Input-Mediator-Output-Input (IMOI) model, and tested their associations with job satisfaction for three categories of mental health professionals (nurses, psychologists/psychotherapists, and social workers). Methods: Job satisfaction was assessed with the Job Satisfaction Survey. Independent variables were classified into four categories: 1) Socio-professional Characteristics; 2) Team Attributes; 3) Team Processes; and 4) Team Emergent States...
2017: BMC Nursing
https://www.readbyqxmd.com/read/29163132/the-influence-of-negative-emotion-on-cognitive-and-emotional-control-remains-intact-in-aging
#13
Artyom Zinchenko, Christian Obermeier, Philipp Kanske, Erich Schröger, Arno Villringer, Sonja A Kotz
Healthy aging is characterized by a gradual decline in cognitive control and inhibition of interferences, while emotional control is either preserved or facilitated. Emotional control regulates the processing of emotional conflicts such as in irony in speech, and cognitive control resolves conflict between non-affective tendencies. While negative emotion can trigger control processes and speed up resolution of both cognitive and emotional conflicts, we know little about how aging affects the interaction of emotion and control...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29157336/dissociated-components-of-executive-control-in-acute-hypobaric-hypoxia
#14
Endre Takács, István Czigler, Lívia Gabriella Pató, László Balázs
INTRODUCTION: The neurocognitive effects of acute hypobaric hypoxia are still largely unknown. This study was designed to test the hypothesis that executive control, an important component of cognition, is especially vulnerable to hypoxia. METHODS: Subjects participated in a simulated hypobaric chamber flight to 5500 m. Four auditory tasks were presented before, during, and after hypoxia: 1) Voice, and 2) Name variant of the Stroop task (both measuring conflict resolution); 3) go/no-go task (GNG; measuring inhibition); and 4) two-choice reaction time task (CRT; which is a noninhibitory control task)...
December 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29154622/how-does-not-left-become-right-electrophysiological-evidence-for-a-dynamic-conflict-bound-negation-processing-account
#15
Carolin Dudschig, Barbara Kaup
Human thought and language is traditionally considered as abstract, amodal, and symbolic. However, recent theories propose that high-level human cognition is directly linked to basic, modal biological systems such as sensorimotor areas. Despite this influential representational debate very little is known regarding whether the mechanisms involved in sensorimotor control are also shared with higher-level cognitive processes, such as language comprehension. We investigated negation as a universal of human language, addressing two key questions: (a) Does negation result in a conflict-like representation? (b) Does negation trigger executive control adjustments in a similar manner as standard information processing conflicts do (e...
November 20, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/29152871/an-explanatory-model-of-dating-violence-risk-factors-in-spanish-adolescents
#16
Alazne Aizpitarte, Itziar Alonso-Arbiol, Fons J R Van de Vijver
Dating violence is a serious public health issue that needs further understanding in terms of risk factors that may be involved in it. The main goal of this study was to test a mediational model of dating violence risk factors. The sample was composed of 477 secondary and college students from Spain (59% females). A dynamic developmental explanatory model considering aggressiveness, insecure attachment, interparental conflict, and peer dating violence was tested using a multigroup structural equation model...
December 2017: Journal of Research on Adolescence: the Official Journal of the Society for Research on Adolescence
https://www.readbyqxmd.com/read/29146926/correlations-and-forecast-of-death-tolls-in-the-syrian-conflict
#17
Kazuki Fujita, Shigeru Shinomoto, Luis E C Rocha
The Syrian armed conflict has been ongoing since 2011 and has already caused thousands of deaths. The analysis of death tolls helps to understand the dynamics of the conflict and to better allocate resources and aid to the affected areas. In this article, we use information on the daily number of deaths to study temporal and spatial correlations in the data, and exploit this information to forecast events of deaths. We found that the number of violent deaths per day in Syria varies more widely than that in England in which non-violent deaths dominate...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29145645/waddlia-chondrophila-a-chlamydia-related-bacterium-has-a-negative-impact-on-human-spermatozoa
#18
D Baud, N Vulliemoz, A Ammerdorffer, J Gyger, G Greub, V Castella, M Stojanov
STUDY QUESTION: What is the impact of Waddlia chondrophila, an emerging Chlamydia-related bacterium associated with miscarriage, on human spermatozoa? SUMMARY ANSWER: W. chondrophila had a negative impact on human spermatozoa (decrease in viability and mitochondrial membrane potential) and was not entirely removed from infected samples by density gradient centrifugation. WHAT IS KNOWN ALREADY: Bacterial infection or colonization might have a deleterious effect on male fertility...
November 14, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29133246/potentially-inappropriate-liver-transplantation-in-the-era-of-the-sickest-first-policy-a-search-for-the-upper-limits
#19
REVIEW
Michael Linecker, Tanja Krones, Thomas Berg, Claus U Niemann, Randolph H Steadman, Philipp Dutkowski, Pierre-Alain Clavien, Ronald W Busuttil, Robert D Truog, Henrik Petrowsky
Liver transplantation has emerged to a highly efficient treatment for a variaty of acute and chronic liver diseases. Organ shortage, however, is becoming an increasing problem worldwide, limiting the applicability of liver transplantation. In addition, potential recipients are becoming sicker, thereby increasing the risk of loosing the graft during transplantation or in the initial post-operative period after liver transplantation (3 months). This trend is challenging the MELD allocation model where sickest candidates are prioritized and no delisting criteria are given...
November 10, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/29127954/human-dimension-of-health-service-management
#20
Jo M Martins, Godfrey Isouard, Brenda Freshman
This article identifies three relevant and valid constructs that are associated with personal and organisational performance that can be used in the training of current and future health service managers: personal engagement at work, emotional intelligence and conflict resolution. A review was undertaken of the literature in human resources management to identify key concepts that bind and strengthen the management of organisations. A curriculum content analysis was then performed of postgraduate health management courses in Australia to assess the extent of inclusion in these areas...
November 13, 2017: Australian Health Review: a Publication of the Australian Hospital Association
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