Hui Wang, Suhui Zuo, Jiaoyun Zheng, Zhi Peng, Xueping Yao, Jie Wang, Horst Christian Weber, Xiaoqun Qin, Yang Xiang, Chi Liu, Ming Ji, Huijun Liu, Lang Pan, Xiangping Qu
Both bombesin receptor-activated protein (BRAP) and its mouse homolog have been found to be expressed in bronchial epithelia but with unclear functions. Using electron microscopy combined with histological assays, we found that BRAP homolog deficiency in mice led to abnormal tracheal cilia. Rab-3A-interacting protein (Rabin8), a protein that might play a role in cilia development, was screened by yeast two-hybrid and further verified to have interaction with human BRAP by co-immunoprecipitation and pull down assays...
September 16, 2023: FEBS Letters