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Daniëla K van Santen, Jannie J van der Helm, Karen Lindenburg, Maarten Schim van der Loeff, Maria Prins
BACKGROUND: HIV-positive people who use drugs (PWUD) start antiretroviral therapy (ART) later than other risk groups, and among HCV-positive PWUD, HCV treatment uptake is low. Nowadays, HCV direct-acting antivirals (DAAs) are available and reimbursed in the Netherlands (since 2014). The Amsterdam Cohort Studies (ACS), initiated in 1985, provides us the opportunity to describe temporal trends in ART and HCV-treatment uptake among PWUD through 2015. METHODS: We analyzed data from PWUD participating in the ACS between 1985 and 2015...
September 2017: International Journal on Drug Policy
François Blanquart, Chris Wymant, Marion Cornelissen, Astrid Gall, Margreet Bakker, Daniela Bezemer, Matthew Hall, Mariska Hillebregt, Swee Hoe Ong, Jan Albert, Norbert Bannert, Jacques Fellay, Katrien Fransen, Annabelle J Gourlay, M Kate Grabowski, Barbara Gunsenheimer-Bartmeyer, Huldrych F Günthard, Pia Kivelä, Roger Kouyos, Oliver Laeyendecker, Kirsi Liitsola, Laurence Meyer, Kholoud Porter, Matti Ristola, Ard van Sighem, Guido Vanham, Ben Berkhout, Paul Kellam, Peter Reiss, Christophe Fraser
HIV-1 set-point viral load-the approximately stable value of viraemia in the first years of chronic infection-is a strong predictor of clinical outcome and is highly variable across infected individuals. To better understand HIV-1 pathogenesis and the evolution of the viral population, we must quantify the heritability of set-point viral load, which is the fraction of variation in this phenotype attributable to viral genetic variation. However, current estimates of heritability vary widely, from 6% to 59%. Here we used a dataset of 2,028 seroconverters infected between 1985 and 2013 from 5 European countries (Belgium, Switzerland, France, the Netherlands and the United Kingdom) and estimated the heritability of set-point viral load at 31% (CI 15%-43%)...
June 2017: PLoS Biology
Daniela Mariosa, Niklas Hammar, Håkan Malmström, Caroline Ingre, Ingmar Jungner, Weimin Ye, Fang Fang, Göran Walldius
OBJECTIVE: To assess the associations of blood biomarkers of carbohydrate, lipid, and apolipoprotein metabolisms with the future risk of amyotrophic lateral sclerosis (ALS). METHODS: In the Apolipoprotein-related MOrtality RISk study, we enrolled 636,132 men and women during 1985-1996 in Stockholm, Sweden, with measurements of serum glucose, total cholesterol, triglycerides, apolipoprotein B (apoB), and apolipoprotein A-I (apoA-I). Serum low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) were either directly measured or calculated from total cholesterol, triglycerides, and apoA-I...
May 2017: Annals of Neurology
Melecia Wright, Daniela Sotres-Alvarez, Michelle A Mendez, Linda Adair
No study has analysed how protein intake from early childhood to young adulthood relate to adult BMI in a single cohort. To estimate the association of protein intake at 2, 11, 15, 19 and 22 years with age- and sex-standardised BMI at 22 years (early adulthood), we used linear regression models with dietary and anthropometric data from a Filipino birth cohort (1985-2005, n 2586). We used latent growth curve analysis to identify trajectories of protein intake relative to age-specific recommended daily allowance (intake in g/kg body weight) from 2 to 22 years, then related trajectory membership to early adulthood BMI using linear regression models...
March 2017: British Journal of Nutrition
Radu Mircea Neagoe, Serban Bancu, Mircea Muresan, Daniela Sala
Starting with a case report, we made a detailed review of the literature, with the purpose of identifying and analyzing the type of iatrogenic vascular lesion following knee arthroscopy and the method of vascular repair. A PubMed literature search was undertaken to locate all reported cases of major vascular iatrogenic injuries during arthroscopic knee procedures. We identified 39 papers which report a total of 62 cases of major iatrogenic popliteal lesions after knee arthroscopy, between 1985 and 2014. The type of arthroscopic intervention performed, the type of iatrogenic vascular lesion encountered, the time passed until its discovery and treatment, the method of vascular reconstruction, and the postoperative course are presented...
July 2015: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
Ard van Sighem, Fumiyo Nakagawa, Daniela De Angelis, Chantal Quinten, Daniela Bezemer, Eline Op de Coul, Matthias Egger, Frank de Wolf, Christophe Fraser, Andrew Phillips
BACKGROUND: Estimates of the size of the undiagnosed HIV-infected population are important to understand the HIV epidemic and to plan interventions, including "test-and-treat" strategies. METHODS: We developed a multi-state back-calculation model to estimate HIV incidence, time between infection and diagnosis, and the undiagnosed population by CD4 count strata, using surveillance data on new HIV and AIDS diagnoses. The HIV incidence curve was modelled using cubic splines...
September 2015: Epidemiology
Federica Grosso, Lorenza Randi, Alessandro Croce, Dario Mirabelli, Roberta Libener, Corrado Magnani, Donata Bellis, Mario Allegrina, Marinella Bertolotti, Daniela Degiovanni, Caterina Rinaudo
PURPOSE: This exploratory study aimed to evaluate the presence of asbestos fibers in the biliary tract of patients living in an asbestos-polluted area using scanning electron microscopy. METHODS: Thin gallbladder sections were obtained from five patients who were operated on for gallbladder stones and the bile fluid of one of the patients was analyzed using variable-pressure scanning electron microscopy coupled with energy-dispersive spectroscopy. All patients were from Casale Monferrato, Italy, a well-known asbestos-polluted city, where the Eternit factory had operated since the beginning of the century until 1985...
July 2015: European Journal of Gastroenterology & Hepatology
Ludwig Kraus, Mimmi Eriksson Tinghög, Annette Lindell, Alexander Pabst, Daniela Piontek, Robin Room
AIMS: In Sweden, alcohol abstention has increased over the last 20 years and consumption has recently decreased after a peak in 2004. To understand the dynamics of these trends the present study aims at estimating age, period and cohort (APC) effects on trends in alcohol use prevalence as well as overall and beverage-specific volume of drinking over the last three decades. METHODS: APC analysis of seven cross-sectional surveys from 1979 to 2011 was conducted using cross-classified random effects models (CCREMs) by gender...
May 2015: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
Daniela K Pilarska, Renate Radek, Wei-Fong Huang, Danail I Takov, Andreas Linde, Leellen F Solter
The historic genus Pleistophora (Plistophora) is a highly polyphyletic clade with invertebrate Microsporidia reassigned to several new genera since the 1980s. Two genera, Endoreticulatus and Cystosporogenes, clearly separate into distinct but closely related clades based on small subunit ribosomal RNA analysis but are included in different families that are each polyphyletic. A microsporidium with morphology resembling the Endoreticulatus/Cystosporogenes clade was isolated from the grasshopper Poecilimon thoracicus from a site in Northwest Bulgaria...
January 2015: Journal of Invertebrate Pathology
Daniëla K van Santen, Jannie J van der Helm, Bart P X Grady, Anneke S de Vos, Mirjam E E Kretzschmar, Ineke G Stolte, Maria Prins
OBJECTIVES: We aimed to identify temporal trends in all-cause and cause-specific mortality rates among people who use drugs (PWUD) compared with the general Dutch population and to determine whether mortality trends differed by hepatitis C virus (HCV)/HIV (co) infection status. DESIGN: Longitudinal cohort study. METHODS: Using data from the Amsterdam Cohort Studies among 1254 PWUD (1985-2012), all-cause and cause-specific standardized mortality ratios (SMRs) were calculated; SMRs were stratified by serological group (HCV/HIV-uninfected, HCV-monoinfected, and HCV/HIV-coinfected) and calendar period...
November 13, 2014: AIDS
Francesco Ursini, Alessandro Grembiale, Saverio Naty, Rosa Daniela Grembiale
The objective of this cross-sectional study is to investigate the relationship between inflammatory markers (C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white blood cell (WBC) count, and complement C3) and insulin resistance (estimated with the surrogate measure homeostasis model assessment of insulin resistance (HOMA-IR)) in Psoriatic arthritis (PsA) patients. Sixty-seven patients with PsA and 138 age- and sex-matched controls were recruited from the Rheumatology Outpatient Clinic of the University of Catanzaro, Catanzaro (Italy)...
December 2014: Clinical Rheumatology
Maria Gnigler, Elisabeth Ralser, Daniela Karall, Gernot Reiter, Ursula Kiechl-Kohlendorfer
AIM: Early sudden unexpected death in infancy (ESUDI) is a rare cause of death occurring in newborns during the first hours of life. Our aim was to find additional data for the identification of risk factors and establishment of prevention strategies. METHODS: We describe three cases of ESUDI and give an overview of the literature. RESULTS: ESUDI was observed in term babies with normal birth weight after good postnatal adaptation within the first four hours of life...
May 2013: Acta Paediatrica
Vittorio Lingiardi, Antonello Colli, Daniela Gentile, Annalisa Tanzilli
This study investigates the relationship between the Depth of elaboration, the therapeutic alliance, and dimensions of the psychotherapy process--the therapist interventions, the patient contributions, and patient/therapist patterns of interaction. Sixty psychotherapy sessions that were audio-taped and transcribed were rated by external judges by using a battery of instruments that included the Psychotherapy Process Q-Set (Jones, 1985, 2000), the Working Alliance Inventory-Observer (Horvath, 1981, 1982; Horvath & Greenberg, 1989), and the Depth Scale of Session Evaluation Questionnaire (Stiles & Snow, 1984a)...
December 2011: Psychotherapy
Simona Menegozzo, Pietro Comba, Daniela Ferrante, Marco De Santis, Giuseppe Gorini, Francesco Izzo, Corrado Magnani, Roberta Pirastu, Andrea Simonetti, Sara Tùnesi, Massimo Menegozzo
The objective of this paper is to investigate mortality among 1247 male asbestos-cement workers employed in an asbestos-cement plant located in Naples. The cohort included 1247 men hired between 1950 and 1986. The follow-up began on January 1st 1965. The vital status and causes of death were ascertained up to December 31 2005. Cause-specific mortality rates of the Campania Region population were used as reference. Relative risks were estimated using Standardized Mortality Ratios (SMRs), and the confidence intervals were calculated at a 95% level (95% CI)...
2011: Annali Dell'Istituto Superiore di Sanità
Johnny C Hong, Henrik Petrowsky, Fady M Kaldas, Douglas G Farmer, Francisco A Durazo, Richard S Finn, Sammy Saab, Steven-Huy Han, Percy Lee, Daniela Markovic, Charles Lassman, Jonathan R Hiatt, Ronald W Busuttil
BACKGROUND: Current criteria for orthotopic liver transplantation (OLT) for cholangiocarcinoma (CCA) remain restricted to early stage and small hilar tumors, excluding patients with locally advanced intrahepatic and hilar CCA for potential cure. The present study was undertaken to define a prognostic scoring system for risk stratification of patients with intrahepatic and hilar CCA who might benefit from OLT and to allow expansion of current OLT criteria. STUDY DESIGN: We conducted a retrospective review of 40 patients who underwent OLT for locally advanced intrahepatic and hilar CCA at our center between February 1985 and June 2010...
April 2011: Journal of the American College of Surgeons
Carlos Ferreira Dos Santos, Vivien Thiemy Sakai, Maria Aparecida de Andrade Moreira Machado, Daniela Nicole Schippers, Andrew Seth Greene
Various molecular biology techniques have become available in the last few years. One of the most revolutionary of these techniques regarding nucleic acid analysis is the polymerase chain reaction (PCR), which was first described in 1985. This method relies on the exponential amplification of specific DNA fragments, resulting in millions of copies that can serve as templates for different kinds of analyses. PCR can be preceded by a reverse transcription (RT) reaction in order to produce cDNA from RNA (RT-PCR)...
March 2004: Journal of Applied Oral Science: Revista FOB
Lidia Rosi Medeiros, Célia Scapin Duarte, Daniela Dornelles Rosa, Maria Isabel Edelweiss, Marcia Edelweiss, Fábio Rosa Silva, Erik Paul Winnnikow, Patrícia Duarte Simões Pires, Maria Inês Rosa
Dynamic contrast-enhanced breast magnetic resonance (MR) is a promising emerging technique for evaluating breast lesions. A quantitative systematic review was performed to estimate the accuracy of breast MR in the diagnosis of high-risk breast lesions and breast cancer. A comprehensive search of the Cochrane Library, MEDLINE, CANCERLIT, LILACS, and EMBASE databases was performed from January 1985 to August 2010. The medical subjects heading (MeSH) and text words for the terms "breast neoplasm", "breast lesions", "breast cancer" and "magnetic resonance" were combined with the MeSH term diagnosis ("sensitivity and specificity")...
April 2011: Breast Cancer Research and Treatment
Mauro Signorelli, Robert Fruscio, Tiziana Dell'Anna, Alessandro Buda, Daniela Giuliani, Lorenzo Ceppi, Rodolfo Milani
BACKGROUND: The role of lymphadenectomy in low-grade endometrial stromal sarcoma (ESS) is controversial. The risk of nodal metastases ranges from 0% to 44%, but data are inconclusive. The objective of this study and of the literature review was to investigate the incidence of nodal involvement in macroscopically early-stage tumors. METHODS: All consecutive patients with histologically proven uterine low-grade ESS who underwent surgery in our institution were considered eligible for the analysis...
November 2010: International Journal of Gynecological Cancer
Stephanie E Combs, Daniela Schulz-Ertner, Jürgen Debus, Andreas von Deimling, Christian Hartmann
PURPOSE: To evaluate the correlation between the 1993 and 2000/2007 World Health Organization (WHO) classification with the outcome in patients with high-grade meningiomas. PATIENTS AND METHODS: Between 1985 and 2004, 73 patients diagnosed with atypical or anaplastic meningiomas were treated with radiotherapy. Sections from the paraffin-embedded tumor material from 66 patients (90%) from 13 different pathology departments were re-evaluated according to the first revised WHO classification from 1993 and the revised classifications from 2000/2007...
December 1, 2011: International Journal of Radiation Oncology, Biology, Physics
Carlos Almeida, Ester Coutinho, Daniela Moreira, Ernestina Santos, José Aguiar
BACKGROUND AND OBJECTIVE: Myasthenia gravis is an autoimmune neuromuscular disease, usually affecting women in the second and third decades. The course is unpredictable during pregnancy and puerperium. Myasthenia gravis can cause major interference in labour and partum and exacerbations of the disease frequently occur. The aim of this series of cases is to analyse retrospectively the anaesthetic management of myasthenia gravis patients and complications during the peripartum period. MATERIALS AND METHODS: Retrospective, single centre study from clinical files of female myasthenia gravis patients who delivered between 1985 and 2007 at Hospital de Santo António, Porto, Portugal...
November 2010: European Journal of Anaesthesiology
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