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https://www.readbyqxmd.com/read/28212426/sustainability-of-common-pool-resources
#1
Raja Rajendra Timilsina, Koji Kotani, Yoshio Kamijo
Sustainability has become a key issue in managing natural resources together with growing concerns for capitalism, environmental and resource problems. We hypothesize that the ongoing modernization of competitive societies, which we refer to as "capitalism," affects human nature for utilizing common pool resources, thus compromising sustainability. To test this hypothesis, we design and implement a set of dynamic common pool resource games and experiments in the following two types of Nepalese areas: (i) rural (non-capitalistic) and (ii) urban (capitalistic) areas...
2017: PloS One
https://www.readbyqxmd.com/read/28202469/establishment-and-maintenance-of-sexual-preferences-that-cause-a-reproductive-isolation-between-medaka-strains-in-close-association
#2
Mayuka Ikawa, Emi Ohya, Hiroka Shimada, Makiko Kamijo, Shoji Fukamachi
Animals choose reproductive partners based on their sexual preferences which are established at a certain time point before, during, or after sexual maturation. The preferences are often divergent within a species, which suppresses gene flow between populations and may promote speciation. There are two strains of medaka (Oryzias latipes) that differ by a single transgene and mate assortatively depending on skin color. Here, we demonstrate that symmetrically biased (mutually exclusive) sexual preferences are (1) gradually established during growth depending on skin color and the color of surrounding fish, (2) strong enough to minimize gene flow between the strains at a population level, and (3) inflexibly retained after sexual maturation, even after weeks of daily mating with partners of the other strain...
February 15, 2017: Biology Open
https://www.readbyqxmd.com/read/28197733/relationship-between-exercise-capacity-and-urinary-liver-type-fatty-acid-binding-protein-in-middle-aged-and-older-individuals
#3
Keisei Kosaki, Atsuko Kamijo-Ikemori, Takeshi Sugaya, Koichiro Tanahashi, Hiroshi Kumagai, Yuriko Sawano, Nobuhiko Akazawa, Song-Gyu Ra, Kenjiro Kimura, Yugo Shibagaki, Seiji Maeda
BACKGROUND: The underlying mechanism linking the decline in exercise capacity with renal dysfunction remains unclear. Urinary liver-type fatty acid-binding protein (L-FABP) levels reflect the degree of peritubular capillary blood flow, an important factor for renal dysfunction with aging. The aim of this study was to examine the relationship between exercise capacity and urinary L-FABP levels. METHODS: This was a cross-sectional study of 187 middle-aged and older individuals (aged 50-83 years) without chronic kidney disease (CKD)...
February 14, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/28194979/synthesis-of-alkylated-pyrimidines-via-photoinduced-coupling-using-benzophenone-as-a-mediator
#4
Shin Kamijo, Kaori Kamijo, Toshihiro Murafuji
The synthesis of alkylated pyrimidines was achieved via benzophenone-mediated photoinduced coupling between saturated heterocycles and sulfonylpyrimidines. The pyrimidine ring was selectively introduced at the nonacidic C(sp3)-H bond proximal to heteroatoms including oxygen, nitrogen, and sulfur. This is a coupling reaction mediated solely by photoexcited benzophenone, an organic molecule, without the aid of any metallic catalysts or reagents.
February 14, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28174142/polyarteritis-nodosa-in-a-patient-with-haemophilia-a
#5
Asuka Tsuji, Yukiko Kiniwa, Fuminao Kamijo, Tomomi Miyake, Atsuko Ohashi, Noriko Senoo, Kazuhisa Urushihata, Ryuhei Okuyama
No abstract text is available yet for this article.
February 3, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28163920/risk-factors-for-the-delayed-onset-of-neuropsychologic-sequelae-following-carbon-monoxide-poisoning
#6
Takeshi Kitamoto, Masanobu Tsuda, Masaki Kato, Fukuki Saito, Yoshito Kamijo, Toshihiko Kinoshita
AIM: Carbon monoxide (CO) poisoning often manifests delayed neuropsychological sequelae. The risks and preventive factors for the development of delayed neuropsychological sequelae are controversial at present. The purpose of this retrospective study was to assess the risk factors for this condition. METHOD: We studied 81 patients with CO poisoning admitted to the Critical Care and Emergency Medicine Center at the Kansai Medical University from 2006 to 2012. All patients (64 males and 17 females; average age, 45...
October 2016: Acute Med Surg
https://www.readbyqxmd.com/read/28125711/monitoring-mitochondrial-complex-i-activity-using-novel-pet-probe-18f-bcpp-ef-allows-early-detection-of-radiotherapy-effect-in-murine-squamous-cell-carcinoma
#7
Chieko Murayama, Akira T Kawaguchi, Akemi Kamijo, Katsuko Naito, Masakatsu Kanazawa, Hideo Tsukada
OBJECTIVES: Aerobic glycolysis, the main pathway of energy production in tumors (Warburg effect) allows detection of tumors by positron emission tomography (PET) using 18F-fluoro-2-deoxy-D-glucose (18F-FDG). Since ionizing radiation (IR) is reported to switch aerobic glycolysis to mitochondrial oxidative phosphorylation, radiotherapeutic efficacy was monitored by the activity of mitochondrial complex I (MC-I), using a new PET probe 18F-BCPP-EF, 18F-2-tert-butyl-4-chloro-5-{6-[2-(2-fluoro-ethoxy)-ethoxy] -pyridine-3-ylmethoxy}-2H-pyridazin-3-one, compared with 18F-FDG uptake and the apoptosis index...
2017: PloS One
https://www.readbyqxmd.com/read/28095870/comparison-of-compressive-forces-caused-by-various-cannulated-cancellous-screws-used-in-arthroscopic-ankle-arthrodesis
#8
Satoshi Kamijo, Tsukasa Kumai, Shogo Tanaka, Tsuyoshi Mano, Yasuhito Tanaka
BACKGROUND: When performing arthroscopic ankle arthrodesis for end-stage ankle arthritis, internal fixation is performed using bone screws after appropriate preparation. However, optimal characteristics of bone screws have not been examined in terms of pressure force. Objective comparisons of bone-screw performance may provide information on procedures for arthroscopic ankle arthrodesis. The study objectives were to determine whether it was possible to measure compressive force changes using the newly developed device and to infer all screw characteristics from measurement results when used in actual surgeries...
January 17, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28093227/wnt-%C3%AE-catenin-signaling-activates-nephronectin-expression-in-osteoblasts
#9
Mikiko Ikehata, Atsushi Yamada, Naoko Morimura, Masakatsu Itose, Tetsuo Suzawa, Tatsuo Shirota, Daichi Chikazu, Ryutaro Kamijo
Nephronectin (Npnt), an extracellular matrix protein, is considered to play critical roles as an adhesion molecule in the development and functions of various organs and tissues, such as the kidneys and bone. In the present study, we found that Wnt3a strongly enhanced Npnt mRNA expression in osteoblast-like MC3T3-E1 cells, while it also induced an increase in Npnt gene expression in both time- and dose-dependent manners via the Wnt/β-catenin signaling pathway. These results suggest novel mechanisms for Wnt3a-induced osteoblast proliferation and cell survival via Npnt gene expression...
January 16, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28070636/extracellular-matrix-loss-in-chondrocytes-after-exposure-to-interleukin-1%C3%AE-in-nadph-oxidase-dependent-manner
#10
Sakie Funato, Rika Yasuhara, Kentaro Yoshimura, Yoichi Miyamoto, Kotaro Kaneko, Tetsuo Suzawa, Daichi Chikazu, Kenji Mishima, Kazuyoshi Baba, Ryutaro Kamijo
Osteoarthritis is a degenerative joint disease caused by excessive death of chondrocytes and loss of the extracellular matrix (ECM) in articular cartilage. We previously reported that reactive oxygen species (ROS) generated by the NADPH oxidase (NOX) isoform NOX-2 are involved in chondrocyte death induced by interleukin-1β (IL-1β). In this study, we investigate the role of NOX-2 in the production and degradation of ECM by chondrocytes. Although IL-1β lowered the mRNA expression of type II collagen (Col2a1) and aggrecan (Acan) in mouse chondrocyte-like ATDC5 cells, RNA silencing of Nox2 did not change the mRNA expression of these major components of the ECM of cartilage...
January 9, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28063188/utility-of-urinary-tubular-markers-for-monitoring-chronic-tubulointerstitial-injury-after-ischemia-reperfusion
#11
Daisuke Ichikawa, Atsuko Kamijo-Ikemori, Takeshi Sugaya, Keiichi Ohata, Mikako Hisamichi, Seiko Hoshino, Kenjiro Kimura, Yugo Shibagaki
BACKGROUND: The aim of this study was to elucidate whether urinary tubular markers during the chronic phase of acute kidney injury (AKI) are associated with chronic tubulointerstitial damage. METHODS: Male human L-type fatty acid binding protein (L-FABP) chromosomal transgenic (Tg) mice underwent ischemic reperfusion (I/R) injury via renal pedicle clamping for either 10 min or 20 min. Contralateral nephrectomy was performed at the time of tissue reperfusion...
January 7, 2017: Nephrology
https://www.readbyqxmd.com/read/27978668/aryl-ketone-catalyzed-radical-allylation-of-c-sp-3-h-bonds-under-photoirradiation
#12
Shin Kamijo, Kaori Kamijo, Kiyotaka Maruoka, Toshihiro Murafuji
The catalytic introduction of an allyl group at nonacidic C(sp(3))-H bonds was achieved under photoirradiation, in which 1,2-bis(phenylsulfonyl)-2-propene acts as an allyl source and 5,7,12,14-pentacenetetrone (PT) works as a C-H bond-cleaving catalyst. A variety of substances, including alkanes, carbamates, ethers, sulfides, and alcohols, were chemoselectively allylated in a single step under neutral conditions. The present transformation is catalyzed solely by an organic molecule, PT, and proceeds smoothly even under visible light irradiation (425 nm) in the case of alkanes as a starting substance...
December 16, 2016: Organic Letters
https://www.readbyqxmd.com/read/27873328/liposome-encapsulated-hemoglobin-improves-tumor-oxygenation-as-detected-by-near-infrared-spectroscopy-in-colon-carcinoma-in-mice
#13
Fumio Kawaguchi, Akira T Kawaguchi, Chieko Murayama, Akemi Kamijo, Munetaka Haida
Liposome-encapsulated hemoglobin (LEH) with high (h-LEH, P50 O2  = 10 mm Hg) or low O2 affinity (l-LEH, P50 O2  = 40 mm Hg) may improve O2 delivery to sensitize tumor tissues for radiotherapy. A total of 10 mL/kg of h-LEH, l-LEH, red blood cells (RBCs), or saline was infused in mice transplanted with murine colon carcinoma with near-infrared spectroscopy (NIRS) detectors set at the tumor (right leg) and intact muscle (left leg). NIRS recorded changes in the amount of oxyhemoglobin (oxyHb), deoxyhemoglobin (deoxyHb), and their sum (tHb) with the animals spontaneously breathing room air (10 min), pure O2 (5 min), and then back to room air...
November 22, 2016: Artificial Organs
https://www.readbyqxmd.com/read/27861895/effects-of-postural-change-from-supine-to-head-up-tilt-on-the-skin-sympathetic-nerve-activity-component-synchronised-with-the-cardiac-cycle-in-warmed-men
#14
Yu Ogawa, Yoshi-Ichiro Kamijo, Shigeki Ikegawa, Shizue Masuki, Hiroshi Nose
KEY POINTS: Humans are unique in controlling body temperature in a hot environment by a large amount of skin blood flow; however, the decrease in total peripheral resistance due to systemic cutaneous vasodilatation and the reduction of venous return to the heart due to blood pooling in the cutaneous vein threatens blood pressure maintenance in the upright position, and occasionally causes heat syncope. Against this condition, cutaneous vasodilatation is reportedly suppressed to maintain arterial pressure; however, the nerve activity responsible for this phenomenon has not been identified...
November 8, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27859977/comparison-of-curative-surgery-and-definitive-chemoradiotherapy-as-initial-treatment-for-patients-with-cervical-esophageal-cancer
#15
Katsushi Takebayashi, Yasuhiro Tsubosa, Satoru Matsuda, Keisuke Kawamorita, Masahiro Niihara, Takahiro Tsushima, Tomoya Yokota, Hiroshi Sato, Yusuke Onozawa, Hirofumi Ogawa, Tomoyuki Kamijo, Tetsuro Onitsuka, Masahiro Nakagawa, Hirofumi Yasui
Esophagectomy and definitive chemoradiotherapy are recognized standard initial treatment modalities for cervical esophageal cancer. The goal of this study was to compare the treatment outcomes of curative surgery with those of chemoradiotherapy in patients who had potentially resectable tumor and who were candidates for surgery. We evaluated the data from 49 consecutive patients who were diagnosed with potentially resectable cervical esophageal cancer and who were deemed candidates for surgery. Thirteen patients were included in the surgery group, and 36 patients were included in chemoradiotherapy group...
November 9, 2016: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/27821945/ankle-knee-and-hip-joint-contribution-to-body-support-during-gait
#16
Tsutomu Fukui, Yasuhisa Ueda, Fumiko Kamijo
[Purpose] Support moment was defined as the sum of ankle plantar flexion, knee and hip extension moments. There are some mechanical relationships among the 3 joints. If these relationships were understood, it might be possible to determine which joint should be strengthened to improve gait. The aims of this study were to examine the mutual relationship among kinetic variables of the 3 joints during different phases. [Subjects and Methods] Twenty-five healthy subjects volunteered for this study. They were asked to walk on a platform at a self-selected speed...
October 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/27805563/computed-tomography-for-the-management-of%C3%A2-exit-site-and-tunnel-infections-in-peritoneal-dialysis-patients%C3%A2
#17
Keina Nozaki, Yuka Kamijo, Mineo Nakatsuka, Takeshi Azuma, Tohru Nakagawa, Hideyo Miyazaki, Tetsuya Fujimura, Hiroshi Fukuhara, Haruki Kume, Yoshitaka Ishibashi, Yukio Homma
PURPOSE: To evaluate the effectiveness of computed tomography (CT) for detection of exit-site and tunnel infections with a Tenckhoff catheter. MATERIALS AND METHODS: The study enrolled patients with exit-site or tunnel infections who underwent ultrasonography (US), CT scans, and subsequent catheter removal or partial catheter reimplantation from 2010 to 2014. Control cases on peritoneal dialysis who underwent abdominal CT scans for other reasons were randomly selected...
December 2016: Clinical Nephrology
https://www.readbyqxmd.com/read/27725374/rnai-mediated-knockdown-of-mouse-melanocortin-4-receptor-in-vitro-and-in-vivo-using-an-sirna-expression-construct-based-on-the-mir-187-precursor
#18
Minoru Kato, Yi-Ying Huang, Mina Matsuo, Yoko Takashina, Kazuyo Sasaki, Yasushi Horai, Aya Juni, Shin-Ichi Kamijo, Kaoru Saigo, Kumiko Ui-Tei, Hajime Tei
RNA interference (RNAi) is a powerful tool for the study of gene function in mammalian systems, including transgenic mice. Here, we report a gene knockdown system based on the human mir-187 precursor. We introduced small interfering RNA (siRNA) sequences against the mouse melanocortin-4 receptor (mMc4r) to alter the targeting of miR-187. The siRNA-expressing cassette was placed under the control of the cytomegalovirus (CMV) early enhancer/chicken β-actin promoter. In vitro, the construct efficiently knocked down the gene expression of a co-transfected mMc4r-expression vector in cultured mammalian cells...
January 27, 2017: Experimental Animals
https://www.readbyqxmd.com/read/27714538/comparison-of-salvage-total-pharyngolaryngectomy-and-cervical-esophagectomy-between-hypopharyngeal-cancer-and-cervical-esophageal-cancer
#19
Katsushi Takebayashi, Yasuhiro Tsubosa, Tomoyuki Kamijo, Yoshiyuki Iida, Atsushi Imai, Masato Nagaoka, Takashi Kitani, Masahiro Niihara, Eisuke Booka, Ayako Shimada, Masahiro Nakagawa, Tetsuro Onitsuka
BACKGROUND: Total pharyngolaryngectomy and cervical esophagectomy (TPLCE) after chemoradiotherapy remains a challenge because of the high rate of complications and few available data on outcomes and safety. The purpose of this study was to evaluate the clinical significance of salvage TPLCE and to compare treatment outcomes between hypopharyngeal cancer and cervical esophageal cancer. METHODS: Data from 37 consecutive patients who were diagnosed with potentially resectable hypopharyngeal and cervical esophageal cancer after chemoradiotherapy were retrospectively analyzed...
October 6, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27695394/risk-factors-for-complications-after-pharyngolaryngectomy-with-total-esophagectomy
#20
Eisuke Booka, Yasuhiro Tsubosa, Masahiro Niihara, Wataru Takagi, Katsushi Takebayashi, Ayako Shimada, Takashi Kitani, Masato Nagaoka, Atsushi Imai, Tomoyuki Kamijo, Yoshiyuki Iida, Tetsuro Onitsuka, Masahiro Nakagawa, Hiroya Takeuchi, Yuko Kitagawa
BACKGROUND: Pharyngolaryngectomy with total esophagectomy (PLTE) is an effective surgical treatment for synchronous or metachronous hypopharyngeal or laryngeal cancer and thoracic esophageal cancer, although it is more invasive than esophagectomy and total pharyngolaryngectomy. The aim of this study was to identify risk factors for complications after PLTE. METHODS: From November 2002 to December 2014, a total of 8 patients underwent PLTE at the Shizuoka Cancer Center Hospital, Shizuoka, Japan...
2016: Esophagus: Official Journal of the Japan Esophageal Society
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