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https://www.readbyqxmd.com/read/28929694/-methodological-quality-evaluation-of-randomized-controlled-trials-for-traditional-chinese-medicines-for-treatment-of-sub-health
#1
Jun Zhao, Xing Liao, Hui Zhao, Zhi-Geng Li, Nan-Yue Wang, Li-Min Wang
To evaluate the methodological quality of the randomized controlled trials(RCTs) for traditional Chinese medicines for treatment of sub-health, in order to provide a scientific basis for the improvement of clinical trials and systematic review. Such databases as CNKI, CBM, VIP, Wanfang, EMbase, Medline, Clinical Trials, Web of Science and Cochrane Library were searched for RCTS for traditional Chinese medicines for treatment of sub-health between the time of establishment and February 29, 2016. Cochrane Handbook 5...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28918414/a-protocol-of-a-cross-sectional-study-evaluating-an-online-tool-for-early-career-peer-reviewers-assessing-reports-of-randomised-controlled-trials
#2
Anthony Chauvin, David Moher, Doug Altman, David L Schriger, Sabina Alam, Sally Hopewell, Daniel R Shanahan, Alessandro Recchioni, Philippe Ravaud, Isabelle Boutron
INTRODUCTION: Systematic reviews evaluating the impact of interventions to improve the quality of peer review for biomedical publications highlighted that interventions were limited and have little impact. This study aims to compare the accuracy of early career peer reviewers who use an innovative online tool to the usual peer reviewer process in evaluating the completeness of reporting and switched primary outcomes in completed reports. METHODS AND ANALYSIS: This is a cross-sectional study of individual two-arm parallel-group randomised controlled trials (RCTs) published in the BioMed Central series medical journals, BMJ, BMJ Open and Annals of Emergency Medicine and indexed with the publication type 'Randomised Controlled Trial'...
September 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28906414/the-effect-of-lidocaine-jelly-on-a-taper-shaped-cuff-of-an-endotracheal-tube-on-the-postoperative-sore-throat-a-prospective-randomized-study-a-consort-compliant-article
#3
RANDOMIZED CONTROLLED TRIAL
Jiwon Lee, Yong-Cheol Lee, Je-Do Son, Jae-Yoon Lee, Hyun-Chang Kim
BACKGROUND: Postoperative sore throat (POST) following general anesthesia with endotracheal intubation is a common complication. We hypothesized that lidocaine jelly applied to the tapered cuff of the endotracheal tube (ETT) might decrease the incidence of POST most commonly arising from endotracheal intubation. METHODS: A total of 208 patients under general anesthesia were randomly assigned into 1 of 2 groups. In the lidocaine group (n = 104), the distal part of ETTs with tapered-shaped cuff was lubricated with lidocaine jelly...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28902240/randomized-clinical-trials-of-dental-bleaching-compliance-with-the-consort-statement-a-systematic-review
#4
Alessandro Dourado Loguercio, Bianca Medeiros Maran, Taíse Alessandra Hanzen, Alexandra Mara de Paula, Jorge Perdigão, Alessandra Reis
We reviewed the literature to evaluate: a) The compliance of randomized clinical trials (RCTs) on bleaching with the CONSORT; and b) the risk of bias of these studies using the Cochrane Collaboration risk of bias tool (CCRT). We searched the Cochrane Library, PubMed and other electronic databases, to find RCTs focused on bleaching (or whitening). The articles were evaluated in compliance with CONSORT in a scale: 0 = no description, 1 = poor description and 2 = adequate description. Descriptive analyses of the number of studies by journal, follow-up period, country and quality assessments were performed with CCRT for assessing risk of bias in RCTs...
August 28, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28890409/the-strocss-statement-strengthening-the-reporting-of-cohort-studies-in-surgery
#5
Riaz Ahmed Agha, Mimi R Borrelli, Martinique Vella-Baldacchino, Rachel Thavayogan, Dennis P Orgill
INTRODUCTION: The development of reporting guidelines over the past 20 years represents a major advance in scholarly publishing with recent evidence showing positive impacts. Whilst over 350 reporting guidelines exist, there are few that are specific to surgery. Here we describe the development of the STROCSS guideline (Strengthening the Reporting of Cohort Studies in Surgery). METHODS AND ANALYSIS: We published our protocol apriori. Current guidelines for case series (PROCESS), cohort studies (STROBE) and randomised controlled trials (CONSORT) were analysed to compile a list of items which were used as baseline material for developing a suitable checklist for surgical cohort guidelines...
September 7, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28886751/uva-ursi-extract-and-ibuprofen-as-alternative-treatments-of-adult-female-urinary-tract-infection-atafuti-study-protocol-for-a-randomised-controlled-trial
#6
Jeanne Trill, Catherine Simpson, Frances Webley, Mike Radford, Louise Stanton, Tom Maishman, Angeliki Galanopoulou, Andrew Flower, Caroline Eyles, Merlin Willcox, Alastair Hay, Gareth Griffiths, Paul Little, George Lewith, Michael Moore
BACKGROUND: Women with acute uncomplicated urine infection are usually treated with antibiotics. One trial has demonstrated that delayed antibiotic treatment offered without symptom relief results in a modest reduction in antibiotic use. There is some evidence that ibuprofen provides symptom relief and reduces antibiotic use. Uva-ursi, a herbal product, has a traditional use for urinary infection symptom relief. We set out to test: in adult women with suspected UTI who accept the delayed prescription strategy: Do NSAIDs or uva-ursi (a herbal product) provide relief from urinary symptoms and reduce antibiotic use...
September 8, 2017: Trials
https://www.readbyqxmd.com/read/28877716/assessing-the-quality-of-reports-about-randomized-controlled-trials-of-scalp-acupuncture-combined-with-another-treatment-for-stroke
#7
Young-Nim You, Myung-Rae Cho, Jae-Hong Kim, Ju-Hyung Park, Gwang-Cheon Park, Min-Yeong Song, Jin-Bong Choi, Jae-Young Han
BACKGROUND: This study was designed to assess the quality of reporting on randomized controlled trials (RCTs) of scalp acupuncture for the treatment of stroke. METHODS: The following 8 databases were systematically investigated from their inception to December 2015: PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, National Institute of Informatics Scholarly and Academic Information Navigator, National Digital Science Library, Korean Traditional Knowledge Portal, and Korean Studies Information Service System...
September 6, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28875400/empirical-consequences-of-current-recommendations-for-the-design-and-interpretation-of-noninferiority-trials
#8
Scott K Aberegg, Andrew M Hersh, Matthew H Samore
BACKGROUND: Noninferiority trials are increasingly common, though they have less standardized designs and their interpretation is less familiar to clinicians than superiority trials. OBJECTIVE: To empirically evaluate a cohort of noninferiority trials to determine 1) their interpretation as recommended by CONSORT, 2) choice of alpha threshold and its sidedness, and 3) differences between methods of analysis such as intention-to-treat and per-protocol. DESIGN: We searched MEDLINE for parallel-group randomized controlled noninferiority trials published in the five highest-impact general medical journals between 2011 and 2016...
September 5, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28875295/a-prospective-randomized-comparison-among-swl-pcnl-and-rirs-for-lower-calyceal-stones-less-than-2%C3%A2-cm-a-multicenter-experience-a-better-understanding-on-the-treatment-options-for-lower-pole-stones
#9
G Bozzini, P Verze, D Arcaniolo, O Dal Piaz, N M Buffi, G Guazzoni, M Provenzano, B Osmolorskij, F Sanguedolce, E Montanari, N Macchione, K Pummer, V Mirone, M De Sio, G Taverna
PURPOSE: To prospectively evaluate the efficacy and safety of RIRS, SWL and PCNL for lower calyceal stones sized 1-2 cm. MATERIALS AND METHODS: Patients with a single lower calyceal stone with an evidence of a CT diameter between 1 and 2 cm were enrolled in this multicenter, randomized, unblinded, clinical trial study. Patients were randomized into three groups: group A: SWL (194 pts); group B: RIRS (207 pts); group C: PCNL (181 pts). Patients were evaluated with KUB radiography (US for uric acid stones) at day 10 and a CT scan after 3 months...
September 5, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28866634/quality-of-reporting-of-harms-in-randomised-controlled-trials-of-pharmacological-interventions-for-rheumatoid-arthritis-a-systematic-review
#10
Muhammad Abdul Hadi, Gretl A McHugh, Philip G Conaghan
BACKGROUND: The quality of reporting of harms data in randomised controlled trials (RCTs) has been reported to be suboptimal. Rheumatoid arthritis (RA) has seen a massive growth in novel pharmacotherapies in the last decade. OBJECTIVE: The aim of this study was to assess the quality of reporting of harms-related data in RCTs evaluating pharmacological interventions for RA according to the CONSORT (Consolidated Standards of Reporting Trials) statement on harms reporting extension...
September 2, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28861912/diagnosis-checking-of-statistical-analysis-in-rcts-indexed-in-pubmed
#11
Paul H Lee, Andy C Y Tse
BACKGROUND: Statistical analysis is essential for reporting of the results of randomized controlled trials (RCTs), as well as evaluating their effectiveness. However, the validity of a statistical analysis also depends on whether the assumptions of that analysis are valid. OBJECTIVE: To review all RCTs published in journals indexed in PubMed during December 2014 to provide a complete picture of how RCTs handle assumptions of statistical analysis. METHODS: We reviewed all RCTs published in December 2014 that appeared in journals indexed in PubMed using the Cochrane highly sensitive search strategy...
September 1, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28857507/innovation-of-clinical-trials-in-china-commentary-on-the-publication-of-consort-extension-for-chinese-herbal-medicine-formulas-2017-recommendations-explanation-and-elaboration
#12
Taixiang Wu, Zhaoxiang Bian, Hongcai Shang, Youping Li
No abstract text is available yet for this article.
August 2017: Journal of Evidence-based Medicine
https://www.readbyqxmd.com/read/28856064/interventions-for-prevention-of-intimate-partner-violence-against-women-in-humanitarian-settings-a-protocol-for-a-systematic-review
#13
Marjan Delkhosh, Ali Ardalan, Abbas Rahimiforoushani, Abbas Keshtkar, Leila Amiri Farahani, Effat Merghati Khoei
INTRODUCTION: Humanitarian emergencies and the number of people who are adversely affected are increasing. In such emergencies, the vulnerability of women and girls to gender-based violence increases signifi-cantly and they often experience high levels of intimate partner violence (IPV). There are a limited number of interventions to reduce gender-based violence (GBV) and IPV in the contexts of humanitarian emergencies, and there is uncertainty about the effectiveness of these preventive interventions...
July 12, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28851296/design-and-rationale-of-the-procalcitonin-antibiotic-consensus-trial-proact-a-multicenter-randomized-trial-of-procalcitonin-antibiotic-guidance-in-lower-respiratory-tract-infection
#14
David T Huang, Derek C Angus, Chung-Chou H Chang, Yohei Doi, Michael J Fine, John A Kellum, Octavia M Peck-Palmer, Francis Pike, Lisa A Weissfeld, Jonathan Yabes, Donald M Yealy
BACKGROUND: Overuse of antibiotics is a major public health problem, contributing to growing antibiotic resistance. Procalcitonin has been reported to be commonly elevated in bacterial, but not viral infection. Multiple European trials found procalcitonin-guided care reduced antibiotic use in lower respiratory tract infection, with no apparent harm. However, applicability to US practice is limited due to trial design features impractical in the US, between-country differences, and residual safety concerns...
August 29, 2017: BMC Emergency Medicine
https://www.readbyqxmd.com/read/28832394/nocebo-effect-in-meni%C3%A3-re-s-disease-a-meta-analysis-of-placebo-controlled-randomized-controlled-trials
#15
Panagiotis A Dimitriadis, Panagiotis Zis
OBJECTIVE: To estimate the frequency and strength of nocebo effects in trials for Menière disease (MD). DATA SOURCES: A literature search was conducted in PUBMED. The search terms we used were " Menière or Menière's," "treatment," and "placebo." Limitations included article type to be Clinical Trial or Randomized Controlled Trial, text availability to be Full text, Species to be Humans and Language to be English. STUDY SELECTION: We included placebo-controlled pharmaceutical RCTs that referred specifically to MD and recruited at least 10 adults in each arm...
October 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28830854/a-mobile-device-app-to-reduce-medication-errors-and-time-to-drug-delivery-during-pediatric-cardiopulmonary-resuscitation-study-protocol-of-a-multicenter-randomized-controlled-crossover-trial
#16
Johan N Siebert, Frederic Ehrler, Christian Lovis, Christophe Combescure, Kevin Haddad, Alain Gervaix, Sergio Manzano
BACKGROUND: During pediatric cardiopulmonary resuscitation (CPR), vasoactive drug preparation for continuous infusions is complex and time-consuming. The need for individual specific weight-based drug dose calculation and preparation places children at higher risk than adults for medication errors. Following an evidence-based and ergonomic driven approach, we developed a mobile device app called Pediatric Accurate Medication in Emergency Situations (PedAMINES), intended to guide caregivers step-by-step from preparation to delivery of drugs requiring continuous infusion...
August 22, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28797065/a-systematic-review-of-the-pharmacokinetic-and-pharmacodynamic-interactions-of-herbal-medicine-with-warfarin
#17
Songie Choi, Dal-Seok Oh, Ui Min Jerng
OBJECTIVES: The aim of this study was to systematically review data regarding pharmacokinetic (PK)-pharmacodynamic (PD) parameters from randomized controlled trials relating to interactions between herbal medicines and warfarin. METHODS: Three electronic databases were searched to identify relevant trials. Two reviewers independently performed the study selection and data extraction. The risk of bias and reporting quality were also assessed independently by two reviewers using the Cochrane risk of bias tool and the consolidated standards of reporting trials (CONSORT)...
2017: PloS One
https://www.readbyqxmd.com/read/28795023/leptocarpus-disjunctus-prolongs-sleeping-time-and-increases-nonrapid-eye-movement-sleep-with-additional-anxiolytic-capacity
#18
Watchara Damjuti, Thanes Fuangfoo, Chanida Palanuvej, Tingli Li, Nijsiri Ruangrungsi
Leptocarpus disjunctus Mast. (Restionaceae) is an edible plant which has indigenous warnings regarding its side effects which can manifest as dizziness. This study investigated hypnotic and anxiolytic properties using several animal models. Anxiolytic activities were evaluated using locomotor determination by elevated plus-maze test, open-field test, and rotarod performance test. Hypnotic activities were performed using pentobarbital sodium-induced sleeping time test. Sleep architecture and quality were obtained from sleep-wake analysis and nonrapid eye movement (NREM) delta activity using electroencephalography...
July 2017: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/28782701/a-systematic-review-of-end-of-life-care-communication-skills-training-for-generalist-palliative-care-providers-research-quality-and-reporting-guidance
#19
REVIEW
Lisa Jane Brighton, Jonathan Koffman, Amy Hawkins, Christine McDonald, Suzanne O'Brien, Vicky Robinson, Shaheen A Khan, Rob George, Irene J Higginson, Lucy Ellen Selman
CONTEXT: End of life care (EoLC) communication skills training for generalist palliative care providers is recommended in policy guidance globally. Whilst many training programmes now exist, there has been no comprehensive evidence synthesis to inform future training delivery and evaluation. OBJECTIVES: To identify and appraise how EoLC communication skills training interventions for generalist palliative care providers are developed, delivered, evaluated, and reported...
August 3, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28761712/statistical-testing-of-baseline-differences-in-sports-medicine-rcts-a-systematic-evaluation
#20
REVIEW
Ross L Peterson, Matthew Tran, Jonathan Koffel, Steven D Stovitz
BACKGROUND/AIM: The CONSORT (Consolidated Standards of Reporting Trials) statement discourages reporting statistical tests of baseline differences between groups in randomised controlled trials (RCTs). However, this practice is still common in many medical fields. Our aim was to determine the prevalence of this practice in leading sports medicine journals. METHODS: We conducted a comprehensive search in Medline through PubMed to identify RCTs published in the years 2005 and 2015 from 10 high-impact sports medicine journals...
2017: BMJ Open Sport & Exercise Medicine
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