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CONSORT

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https://www.readbyqxmd.com/read/28203078/a-survey-of-emedia-delivered-interventions-for-schizophrenia-used-in-randomized-controlled-trials
#1
Farooq Naeem, Tariq Munshi, Shuo Xiang, Megan Yang, Farhad Shokraneh, Yumeen Syed, Muhammad Ayub, Clive E Adams, Saeed Farooq
BACKGROUND: Randomized trials evaluating electronic Media (eMedia) delivery of interventions are increasingly frequent in mental health. Although a number of reviews have reported efficacy of these interventions, none has reviewed the type of eMedia interventions and quality of their description. We therefore decided to conduct a survey of eMedia-delivered interventions for schizophrenia. METHODS: We surveyed all relevant trials reliably identified in the Cochrane Schizophrenia Group's comprehensive register of trials by authors working independently...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28196813/harms-of-outcome-switching-in-reports-of-randomised-trials-consort-perspective
#2
Douglas G Altman, David Moher, Kenneth F Schulz
No abstract text is available yet for this article.
February 14, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28190464/a-chinese-patent-medicine-salvia-miltiorrhiza-depside-salts-for-infusion-combined-with-conventional-treatment-for-patients-with-angina-pectoris-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#3
Yili Zhang, Yanming Xie, Xing Liao, Qiulei Jia, Yan Chai
BACKGROUND: Currently, many trials have been conducted to investigate the beneficial and harmful effects of Salvia miltiorrhiza depside salts for infusion for treating patients with angina pectoris. It is important to systematically and criticallyevaluate the existing literature into providing a pooled effect to examine outcomes of angina pectoris with Salvia miltiorrhiza depside salts for infusion. PURPOSE: A systematic review and meta-analysis were performed to determine the clinical curative effect and safety of Salvia miltiorrhiza depside salts for infusion for angina pectoris and provide clear evidence to inform clinical practice...
February 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28169243/efficacy-of-compound-kushen-injection-plus-radiotherapy-on-nonsmall-cell-lungcancer-a-systematic-review-and-meta-analysis
#4
Shanshan Wang, Xiaobo Lian, Miaomiao Sun, Lei Luo, Lizhong Guo
OBJECTIVE: To evaluate the benefits of compound Kushen injection (CKI) combined with radiotherapy for nonsmall cell lung cancer. MATERIALS AND METHODS: We searched nine electronic databases and six gray literature databases comprehensively until June 2015. Two reviewers independently selected and assessed the included trials according to the inclusion and exclusion criteria. The risk of bias tool from the Cochrane Handbook version 5.1.0, the Review Manager 5.3 software was employed for data analysis...
October 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28168602/preliminary-evidence-on-the-uptake-use-and-benefits-of-the-consort-pro-extension
#5
Rebecca Mercieca-Bebber, Julie Rouette, Melanie Calvert, Madeleine T King, Lori McLeod, Patricia Holch, Michael J Palmer, Michael Brundage
PURPOSE: This study assessed the uptake of the CONsolidated Standards of Reporting Trials (CONSORT)-Patient-Reported Outcomes (PRO) statement; determined if use of CONSORT-PRO was associated with more complete reporting of PRO endpoints in randomised controlled trials (RCTs) and identified the extent to which high-impact journals publishing RCTs with PRO endpoints endorse CONSORT-PRO. METHODS: CONSORT-PRO citations were identified by systematically searching Medline, EMBASE and Google from 2013 (year CONSORT-PRO released) to 17 December 2015...
February 7, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28165322/when-complex-neuronal-structures-may-not-matter
#6
Adriane G Otopalik, Alexander C Sutton, Matthew Ryan Banghart, Eve Marder
Much work has explored animal-to-animal variability and compensation in ion channel expression. Yet, little is known regarding the physiological consequences of morphological variability. We quantify animal-to-animal variability in cable lengths (CV = 0.4) and branching patterns in the Gastric Mill (GM) neuron, an identified neuron type with highly-conserved physiological properties in the crustacean stomatogastric ganglion (STG) of Cancer borealis. We examined passive GM electrotonic structure by measuring the amplitudes and apparent reversal potentials (Erevs) of inhibitory responses evoked with focal glutamate photo-uncaging in the presence of TTX...
February 6, 2017: ELife
https://www.readbyqxmd.com/read/28159507/impact-of-the-consort-statement-endorsement-in-the-completeness-of-reporting-of-randomized-clinical-trials-in-restorative-dentistry
#7
Rafael Sarkis-Onofre, Victório Poletto Neto, Maximiliano Sérgio Cenci, Tatiana Pereira-Cenci, David Moher
OBJECTIVES: The aim of this study was to assess if journal endorsement of the CONSORT Statement is associated with improved completeness of reporting of randomized controlled trials (RCTs) in restorative dentistry. MATERIALS AND METHODS: RCTs in restorative dentistry published in two journals that have (Journal of Dentistry and Clinical Oral Investigations) and have not (Operative Dentistry and Journal of Prosthetic Dentistry) endorsed the CONSORT Statement were selected...
January 31, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28153933/reducing-falls-after-hospital-discharge-a-protocol-for-a-randomised-controlled-trial-evaluating-an-individualised-multimodal-falls-education-programme-for-older-adults
#8
Anne-Marie Hill, Christopher Etherton-Beer, Steven M McPhail, Meg E Morris, Leon Flicker, Ronald Shorr, Max Bulsara, Den-Ching Lee, Jacqueline Francis-Coad, Nicholas Waldron, Amanda Boudville, Terry Haines
INTRODUCTION: Older adults frequently fall after discharge from hospital. Older people may have low self-perceived risk of falls and poor knowledge about falls prevention. The primary aim of the study is to evaluate the effect of providing tailored falls prevention education in addition to usual care on falls rates in older people after discharge from hospital compared to providing a social intervention in addition to usual care. METHODS AND ANALYSES: The 'Back to My Best' study is a multisite, single blind, parallel-group randomised controlled trial with blinded outcome assessment and intention-to-treat analysis, adhering to CONSORT guidelines...
February 2, 2017: BMJ Open
https://www.readbyqxmd.com/read/28148248/effect-of-removable-functional-appliances-on-mandibular-length-in-patients-with-class-ii-with-retrognathism-systematic-review-and-meta-analysis
#9
Adriana Santamaría-Villegas, Rubén Manrique-Hernandez, Emery Alvarez-Varela, Claudia Restrepo-Serna
BACKGROUND: Orthopedic functional devices, are used to improve mandibular length in skeletal class II patients. However, the orthopedic functional device with the best effect to increasing the mandibular length, has not been identified before. Thus, the aim of the present investigation was to evaluate Randomized Controlled Trials (RCT), to determine the best functional appliance improving mandibular length in subjects with retrognathism. METHODS: A systematic review and meta-analysis was performed, including studies published and indexed in databases between 1966 and 2016...
February 1, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28143414/impact-of-oral-hygiene-involving-toothbrushing-versus-chlorhexidine-in-the-prevention-of-ventilator-associated-pneumonia-a-randomized-study
#10
Claudia Fernanda de Lacerda Vidal, Aurora Karla de Lacerda Vidal, José Gildo de Moura Monteiro, Aracele Cavalcanti, Ana Paula Trindade Henriques, Márcia Oliveira, Michele Godoy, Mirella Coutinho, Pollyanna Dutra Sobral, Claudia Ângela Vilela, Bárbara Gomes, Marta Amorim Leandro, Ulisses Montarroyos, Ricardo de Alencar Ximenes, Heloísa Ramos Lacerda
BACKGROUND: Nosocomial pneumonia has correlated to dental plaque and to oropharynx colonization in patients receiving mechanical ventilation. The interruption of this process, by preventing colonization of pathogenic bacteria, represents a potential procedure for the prevention of ventilator-associated pneumonia (VAP). METHODS: The study design was a prospective, randomized trial to verify if oral hygiene through toothbrushing plus chlorhexidine in gel at 0.12% reduces the incidence of ventilatior-associated pneumonia, the duration of mechanical ventilation, the length of hospital stay and the mortality rate in ICUs, when compared to oral hygiene only with chlorhexidine, solution of 0...
January 31, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28138753/-evaluation-of-methodological-quality-in-published-rcts-on-cataract-surgery-pilot-study-on-the-degree-of-adherence-to-consort-statement-requirements-and-their-qualitative-validity
#11
C Baulig, F Krummenauer, S Knippschild
BACKGROUND: The CONSORT statement can be considered as a guideline to ensure transparency in the reporting of randomized clinical trials (RCT), in addition to specific author instructions and requirements of journals. It provides a total of 25 criteria and 12 additional subcriteria on methodological and regulatorical determinants of clinical trials. The availability of the CONSORT recommendations, however, does not necessarily imply adherence to their obligations and correct realisation of the latter from a methodological perspective, so that even in ophthalmology a lack of transparency in trial reporting cannot be excluded...
January 30, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28126299/acute-and-late-adverse-events-associated-with-radical-radiation-therapy-prostate-cancer-treatment-a-systematic-review-of-clinician-and-patient-toxicity-reporting-in-randomized-controlled-trials
#12
REVIEW
Patricia Holch, Ann M Henry, Susan Davidson, Alexandra Gilbert, Jacqueline Routledge, Leanne Shearsmith, Kevin Franks, Emma Ingleson, Abigail Albutt, Galina Velikova
PURPOSE: This review aimed to determine the clinician and patient reported outcome (PRO) instruments currently usedin randomized controlled trials (RCTs) of radical radiation therapy for nonmetastatic prostate cancer to report acute and late adverse events (AEs), review the quality of methodology and PRO reporting, and report the prevalence of acute and late AEs. METHODS AND MATERIALS: The MEDLINE, EMBASE, and Cochrane databases were searched between April and August 2014 according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement...
March 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28122555/reaching-the-unreached-through-trained-and-skilled-birth-attendants-in-ethiopia-a-cluster-randomized-controlled-trial-study-protocol
#13
Taddese Alemu Zerfu, Henok Taddese, Tariku Nigatu, Girma Tenkolu, Joshua P Vogel, Dina Khan-Neelofur, Sibhatu Biadgilign, Amare Deribew
BACKGROUND: Despite improvements since 1990 to 2014, maternal mortality ratio (MMR) remains high in Ethiopia. One of the key drivers of maternal mortality in Ethiopia is the very low coverage of Skilled Birth attendance (SBA) in rural Ethiopia. This cluster randomized trial piloted an innovative approach of deploying trained community reproductive nurses (CORN) to hard to reach/unreachable rural Ethiopia to improve the coverage of SBA. METHODS: We used a three-arm cluster randomized trial to test the effect of deploying CORN in rural communities in South Ethiopia to improve SBA and other maternal health indicators...
January 26, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28122156/hematology-journals-do-not-sufficiently-adhere-to-reporting-guidelines-a-systematic-review
#14
Cole Wayant, Caleb Smith, Matt Sims, Matt Vassar
BACKGROUND: Reporting guidelines and trial/review registration policies have been instituted in order to minimize bias and improve research practices. OBJECTIVE: The objective of this study was to investigate the policies of Hematology journals concerning reporting guideline adoption and trial/review registration. METHODS: We performed a web-based data abstraction from the Instructions for Authors of 67 Hematology journals catalogued in the Expanded Science Citation Index of the 2014 Journal Citation Reports to identify whether each journal required, recommended, or made no mention of the following reporting guidelines: EQUATOR, ICMJE, CONSORT, MOOSE, QUOROM, PRISMA, STARD, STROBE, ARRIVE, and CARE...
January 25, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28116777/pharmacological-treatment-for-antipsychotic-related-constipation
#15
REVIEW
Susanna Every-Palmer, Giles Newton-Howes, Mike J Clarke
BACKGROUND: Antipsychotic-related constipation is a common and serious adverse effect, especially for people taking clozapine. Clozapine has been shown to impede gastrointestinal motility, leading to constipation, and has been reported in up to 60% of patients receiving clozapine. In rare cases, complications can be fatal. Appropriate laxatives should be prescribed to treat constipation in people taking antipsychotics, but there is a lack of guidance on the comparative effectiveness and harms of different agents in this population...
January 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28109653/an-examination-of-outlaw-motorcycle-gangs-and-their-involvement-in-the-illicit-drug-market-and-the-effectiveness-of-anti-association-legislative-responses
#16
Terry Goldsworthy, Laura McGillivray
BACKGROUND: In 2013 the Queensland Government introduced criminal association and mandatory sentencing laws for members of outlaw motorcycle gangs (OMCGs). Forms of "criminal association" or "anti-bikie" laws have been introduced in several Australian jurisdictions, and recent High Court decisions upholding their constitutionality will ensure that they remain part of our justice landscape. Generally, the aims of these laws are to declare a specific organisation as "criminal" and impose various legal orders and offences that thwart the consorting of members and address organised crime, such as unexplained wealth regimes...
January 18, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28109324/reporting-of-critical-care-trial-abstracts-a-comparison-before-and-after-the-announcement-of-consort-guideline-for-abstracts
#17
Akira Kuriyama, Naomi Takahashi, Takeo Nakayama
BACKGROUND: An extension of the Consolidated Standards of Reporting Trials (CONSORT) statement provides a checklist of items to improve the reporting quality of abstracts of randomized controlled trials (RCTs). However, authors of abstracts in some fields have poorly adhered to this guideline. We did an extensive literature survey to examine the quality of reporting trial abstracts in major critical care journals before and after announcement of the CONSORT guideline for abstracts. METHODS: We reviewed abstracts of RCTs published in four major critical care journals with publication dates ranging from 2006 to 2007 (pre-CONSORT) and from 2011 to 2012 (post-CONSORT): Intensive Care Medicine (ICM), Critical Care (CC), American Journal of Respiratory and Critical Care Medicine (AJRCCM), and Critical Care Medicine (CCM)...
January 21, 2017: Trials
https://www.readbyqxmd.com/read/28109321/stepped-wedge-cluster-randomized-controlled-trial-designs-a-review-of-reporting-quality-and-design-features
#18
REVIEW
Michael J Grayling, James M S Wason, Adrian P Mander
BACKGROUND: The stepped wedge (SW) cluster randomized controlled trial (CRCT) design is being used with increasing frequency. However, there is limited published research on the quality of reporting of SW-CRCTs. We address this issue by conducting a literature review. METHODS: Medline, Ovid, Web of Knowledge, the Cochrane Library, PsycINFO, the ISRCTN registry, and ClinicalTrials.gov were searched to identify investigations employing the SW-CRCT design up to February 2015...
January 21, 2017: Trials
https://www.readbyqxmd.com/read/28103420/do-journals-enforce-their-own-instructions-to-authors
#19
Mark A Klebanoff
Compared to reports of observational research, clinical trial manuscripts are standardized. In 2004 the International Committee of Medical Journal Editors (ICMJE) announced that trials beginning enrollment as of July 1, 2005 must be publicly 'registered' before the first participant is enrolled to be considered for publication in a member journal (DeAngelis CD, et al. JAMA 2004;292:1363-1364). Registries must include important parameters including the interventions, the primary outcome and the target sample size...
January 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28098954/use-of-play-therapy-in-nursing-process-a-prospective-randomized-controlled-study
#20
Emel Sezici, Ayse Ferda Ocakci, Hasibe Kadioglu
PURPOSE: Play therapy is a nursing intervention employed in multidisciplinary approaches to develop the social, emotional, and behavioral skills of children. In this study, we aim to determine the effects of play therapy on the social, emotional, and behavioral skills of pre-school children through the nursing process. DESIGN: A single-blind, prospective, randomized controlled study was undertaken. The design, conduct, and reporting of this study adhere to the Consolidated Standards of Reporting Trials (CONSORT) guidelines...
January 18, 2017: Journal of Nursing Scholarship
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