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https://www.readbyqxmd.com/read/28918183/survival-after-surgery-for-oral-cancer-a-30-year-experience
#1
T K Ong, C Murphy, A B Smith, A N Kanatas, D A Mitchell
Oral squamous cell carcinoma is the most common intraoral malignancy, for which we advocate radical primary resection with adjuvant treatment where indicated. The main aims of this paper are to identify the overall survival of a consecutive series of patients and to relate survival to clinical and pathological factors. Kaplan-Meier curves were produced for site, sex, TNM status, and use of postoperative radiotherapy. The data were analysed using IBM SPSS Statistics for Windows and probabilities of less than 0...
September 13, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28916803/tea-with-winnicott-by-brett-kahr-with-illustrations-by-alison-bechdel-karnac-books-london-england-2016-288pp
#2
Merle Molofsky
No abstract text is available yet for this article.
December 2016: American Journal of Psychoanalysis
https://www.readbyqxmd.com/read/28916688/new-badger-culls-for-england-announced-by-defra
#3
(no author information available yet)
No abstract text is available yet for this article.
September 16, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28916604/coronary-perforation-complicating-percutaneous-coronary-intervention-in-patients-with-a-history-of-coronary-artery-bypass-surgery-an-analysis-of-309-perforation-cases-from-the-british-cardiovascular-intervention-society-database
#4
Tim Kinnaird, Richard Anderson, Nick Ossei-Gerning, James Cockburn, Alex Sirker, Peter Ludman, Mark de Belder, Thomas W Johnson, Samuel Copt, Azfar Zaman, Mamas A Mamas
BACKGROUND: The evidence base for coronary perforation (CP) occurring during percutaneous coronary intervention in patients with a history of coronary artery bypass surgery (PCI-CABG) is limited and the long-term effects unclear. Using a national PCI database, the incidence, predictors, and outcomes of CP during PCI-CABG were defined. METHODS AND RESULTS: Data were analyzed on all PCI-CABG procedures performed in England and Wales between 2005 and 2013. Multivariate logistic regressions and propensity scores were used to identify predictors of CP and its association with outcomes...
September 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28915829/how-often-do-mosquitoes-bite-humans-in-southern-england-a-standardised-summer-trial-at-four-sites-reveals-spatial-temporal-and-site-related-variation-in-biting-rates
#5
Victor A Brugman, Marion E England, Joanne Stoner, Laura Tugwell, Lara E Harrup, Anthony J Wilson, Jolyon M Medlock, James G Logan, Anthony R Fooks, Peter P C Mertens, Nicholas Johnson, Simon Carpenter
BACKGROUND: This field-based study examined the abundance and species complement of mosquitoes (Diptera: Culicidae) attracted to humans at four sites in the United Kingdom (UK). The study used a systematic approach to directly measure feeding by mosquitoes on humans at multiple sites and using multiple volunteers. Quantifying how frequently humans are bitten in the field by mosquitoes is a fundamental parameter in assessing arthropod-borne virus transmission. METHODS: Human landing catches were conducted using a standardised protocol by multiple volunteers at four rural sites between July and August 2013...
September 15, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28914440/olaratumab-in-combination-with-doxorubicin-for-the-treatment-of-advanced-soft-tissue-sarcoma-an-evidence-review-group-perspective-of-a-national-institute-for-health-and-care-excellence-single-technology-appraisal
#6
REVIEW
Irina A Tikhonova, Tracey Jones-Hughes, James Dunham, Fiona C Warren, Sophie Robinson, Peter Stephens, Martin Hoyle
The manufacturer of olaratumab (Lartruvo(®)), Eli Lilly & Company Limited, submitted evidence for the clinical and cost effectiveness of this drug, in combination with doxorubicin, for untreated advanced soft tissue sarcoma (STS) not amenable to surgery or radiotherapy, as part of the National Institute for Health and Care Excellence (NICE) Single Technology Appraisal process. The Peninsula Technology Assessment Group, commissioned to act as the Evidence Review Group (ERG), critically reviewed the company's submission...
September 15, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28914219/-euthanasia-and-advanced-dementia
#7
B Keizer
Somewhere around 1975 there was a shift in our perception of suffering that is soon followed by death: it seemed a good idea to skip this unhappy stage of life. A complicated national debate arose, and continues to this day, about whether a life may be prematurely terminated in cases of insoluble misery. Legislation came into effect 2002, after 30 years of deliberation, and the rest of the world looked on in horror. England, in particular, liked to point out that the Dutch were on a very slippery slope.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28914122/improving-health-in-prisons-from-evidence-to-policy-to-implementation-experiences-from-the-uk
#8
Jane Leaman, Anna Amelia Richards, Lynn Emslie, Eamonn Joseph O'Moore
Purpose The purpose of this paper is to understand the components of a high-quality prison healthcare system and the impact, ten-years on, of the transfer of accountability in England, from a justice ministry to a health ministry. Design/methodology/approach A rapid the evidence review was undertaken, which included a review of 82 papers and qualitative interviews with key informants. The concepts and themes identified were summarised and analysed through a framework analysis, designed to improve population outcomes and address health inequalities...
September 11, 2017: International Journal of Prisoner Health
https://www.readbyqxmd.com/read/28912647/accelerometery-and-heart-rate-responses-of-professional-fast-medium-bowlers-in-one-day-and-multi-day-cricket
#9
James A Johnstone, Gerwyn Hughes, Andrew C Mitchell, Paul A Ford, Tim Watson, Rob Duffield, Dan Gordon, Justin D Roberts, Andrew T Garrett
The physical demands of fast-medium bowling are increasingly being recognised, yet comparative exploration of the differing demands between competitive formats (i.e. one-day [OD] versus multi-day [MD] matches) remain minimal. The aim of this study was to describe in-match physiological profiles of professional fast-medium bowlers from England across different versions of competitive matches using a multivariable wearable monitoring device. Seven professional cricket fast-medium bowlers wore the Bioharness(TM) monitoring device during matches, over three seasons (>80 hours in-match)...
September 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28912604/oral-health-promotion-in-the-community-pharmacy-an-evaluation-of-a-pilot-oral-health-promotion-intervention
#10
A Sturrock, H Cussons, C Jones, C Woodcock, L Bird
Introduction Poor oral health is a significant public health concern, costing the NHS in England £3.4 billion annually. Community pharmacies are easily accessible, frequently visited by patients and the community pharmacy contractual framework requires pharmacies to provide healthy living advice to patients - therefore offering a little explored avenue for the delivery of oral health interventions.Methodology A pilot oral health promotion intervention was introduced in five pharmacies in deprived areas of County Durham between September and December 2016...
September 15, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28912195/associations-between-participation-in-organised-physical-activity-in-the-school-or-community-outside-school-hours-and-neighbourhood-play-with-child-physical-activity-and-sedentary-time-a-cross-sectional-analysis-of-primary-school-aged-children-from-the-uk
#11
Russell Jago, Corrie Macdonald-Wallis, Emma Solomon-Moore, Janice L Thompson, Debbie A Lawlor, Simon J Sebire
OBJECTIVES: To assess the extent to which participation in organised physical activity in the school or community outside school hours and neighbourhood play was associated with children's physical activity and sedentary time. DESIGN: Cross-sectional study. SETTING: Children were recruited from 47 state-funded primary schools in South West England. PARTICIPANTS: 1223 children aged 8-9 years old. OUTCOME MEASURES: Accelerometer-assessed moderate-to-vigorous-intensity physical activity (MVPA) and sedentary time...
September 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/28912170/liver-disease-mortality-varies-widely-across-england
#12
Anne Gulland
No abstract text is available yet for this article.
September 14, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28911359/interferon-gamma-response-to-the-treatment-of-active-pulmonary-and-extra-pulmonary-tuberculosis
#13
L Liang, R Shi, X Liu, X Yuan, S Zheng, G Zhang, W Wang, J Wang, K England, L E Via, Y Cai, L C Goldfeder, L E Dodd, C E Barry, R Y Chen
BACKGROUND: Interferon-gamma (IFN-γ) release assays (IGRAs) are used to diagnose tuberculosis (TB) but not to measure treatment response. OBJECTIVE: To measure IFN-γ response to active anti-tuberculosis treatment. DESIGN: Patients from the Henan Provincial Chest Hospital, Henan, China, with TB symptoms and/or signs were enrolled into this prospective, observational cohort study and followed for 6 months of treatment, with blood and sputum samples collected at 0, 2, 4, 6, 8, 16 and 24 weeks...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28910593/construction-of-a-north-american-cancer-survival-index-to-measure-progress-of-cancer-control-efforts
#14
Christopher J Johnson, Hannah K Weir, Angela Mariotto, Reda Wilson, Diane Nishri
INTRODUCTION: Population-based cancer survival data provide insight into the effectiveness of health care delivery. Comparing survival for all cancer sites combined is challenging, because the primary cancer site and age distribution of patients may differ among areas or change over time. Cancer survival indices (CSIs) are summary measures of survival for cancers of all sites combined and are used in England and Europe to monitor temporal trends and examine geographic differences in survival...
September 14, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28905485/public-expenditure-costs-of-carers-leaving-employment-in-england-2015-2016
#15
Linda Pickard, Derek King, Nicola Brimblecombe, Martin Knapp
In the context of global population ageing, the reconciliation of employment and unpaid caring is becoming an important social issue. The estimation of the public expenditure costs of carers leaving employment is a valuable measure that is of considerable interest to policy makers. In 2012, the Personal Social Services Research Unit estimated that the public expenditure costs of unpaid carers leaving employment in England were approximately £1.3 billion a year, based on the costs of Carer's Allowance and lost tax revenues on forgone incomes...
September 14, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28905378/do-reduced-hospital-mortality-rates-lead-to-increased-utilization-of-inpatient-emergency-care-a-population-based-cohort-study
#16
Mauro Laudicella, Stephen Martin, Paolo Li Donni, Peter C Smith
OBJECTIVES: To measure the impact of the improvement in hospital survival rates on patients' subsequent utilization of unplanned (emergency) admissions. DATA SOURCES/STUDY SETTING: Unplanned admissions occurring in all acute hospitals of the National Health Service in England between 2000 and 2009, including 286,027 hip fractures, 375,880 AMI, 387,761 strokes, and 9,966,246 any cause admissions. STUDY DESIGN: Population-based retrospective cohort study...
September 14, 2017: Health Services Research
https://www.readbyqxmd.com/read/28904806/do-clinicians-receive-adequate-training-to-identify-trafficked-persons-a-scoping-review-of-nhs-foundation-trusts
#17
Charles Dr Thompson, Arun Mahay, David Stuckler, Sarah Steele
OBJECTIVE: We investigate whether physicians in secondary care in the English NHS receive adequate training to recognise and appropriately refer for services those persons suspected to be victims of human trafficking. DESIGN: Freedom of Information requests were sent to the 105 England's NHS Trusts delivering acute care in England. SETTING: NHS Trusts providing secondary care in England. PARTICIPANTS: English NHS Trusts...
September 2017: JRSM Open
https://www.readbyqxmd.com/read/28904595/a-cross-continental-study-on-children-s-drawings-of-football-players-implications-for-understanding-key-issues-and-controversies-in-human-figure-drawings
#18
Bahman Baluch, Linda J Duffy, Rokhsareh Badami, Elisangela C Ap Pereira
Professionals examine various aspects of girls' and boys' drawings as a way of understanding their intelligence, personality and emotional state. However, the extent to which such measures could be universally generalised or attributed to a specific cultural norm is still a debatable issue. In the present study five key features of children's drawings namely: the size (height) of the drawings, profile or full face, figure in action or static, shaded or non-shaded and the nature of additional details were examined from a cross-cultural perspective, and by providing a topic (football) for which children's drawing of a human figure could provide opportunities for the latter indices to manifest and flourish...
August 2017: Europe's journal of psychology
https://www.readbyqxmd.com/read/28904139/an-edrioasteroid-from-the-silurian-herefordshire-lagerst%C3%A3-tte-of-england-reveals-the-nature-of-the-water-vascular-system-in-an-extinct-echinoderm
#19
Derek E G Briggs, Derek J Siveter, David J Siveter, Mark D Sutton, Imran A Rahman
Echinoderms are unique in having a water vascular system with tube feet, which perform a variety of functions in living forms. Here, we report the first example of preserved tube feet in an extinct group of echinoderms. The material, from the Silurian Herefordshire Lagerstätte, UK, is assigned to a new genus and species of rhenopyrgid edrioasteroid, Heropyrgus disterminus The tube feet attach to the inner surface of compound interradial plates and form two sets, an upper and a lower, an arrangement never reported previously in an extant or extinct echinoderm...
September 13, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28904128/integration-of-kinase-and-calcium-signaling-at-the-level-of-chromatin-underlies-inducible-gene-activation-in-t-cells
#20
Ruth Brignall, Pierre Cauchy, Sarah L Bevington, Bethany Gorman, Angela O Pisco, James Bagnall, Christopher Boddington, William Rowe, Hazel England, Kevin Rich, Lorraine Schmidt, Nigel P Dyer, Mark A Travis, Sascha Ott, Dean A Jackson, Peter N Cockerill, Pawel Paszek
TCR signaling pathways cooperate to activate the inducible transcription factors NF-κB, NFAT, and AP-1. In this study, using the calcium ionophore ionomycin and/or PMA on Jurkat T cells, we show that the gene expression program associated with activation of TCR signaling is closely related to specific chromatin landscapes. We find that calcium and kinase signaling cooperate to induce chromatin remodeling at ∼2100 chromatin regions, which demonstrate enriched binding motifs for inducible factors and correlate with target gene expression...
September 13, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
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