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https://www.readbyqxmd.com/read/27913626/ring-enhancing-spinal-cord-lesions-in-neuromyelitis-optica-spectrum-disorders
#1
Nicholas L Zalewski, Padraig P Morris, Brian G Weinshenker, Claudia F Lucchinetti, Yong Guo, Sean J Pittock, Karl N Krecke, Timothy J Kaufmann, Dean M Wingerchuk, Neeraj Kumar, Eoin P Flanagan
OBJECTIVE: We assessed the frequency and characteristics of ring-enhancing spinal cord lesions in neuromyelitis optica spectrum disorder (NMOSD) myelitis and myelitis of other cause. METHODS: We reviewed spinal cord MRIs for ring-enhancing lesions from 284 aquaporin-4 (AQP4)-IgG seropositive patients at Mayo Clinic from 1996 to 2014. Inclusion criteria were as follows: (1) AQP4-IgG seropositivity, (2) myelitis attack and (3) MRI spinal cord demonstrating ring-enhancement...
December 2, 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27911973/prevalence-of-osteopenia-and-osteoporosis-in-patients-with-noncystic-fibrosis-bronchiectasis
#2
Nathan Diehl, Margaret M Johnson
OBJECTIVE: The objective of our study was to define the prevalence of osteoporosis and osteopenia in patients with noncystic fibrosis bronchiectasis (NCFB). METHODS: We conducted a retrospective chart review of all patients with physician-diagnosed NCFB evaluated at Mayo Clinic Florida between January 1, 2011 and June 3, 2013. RESULTS: A total of 113 patients with physician-diagnosed NCFB and confirmatory findings on computed tomography scan were identified...
December 2016: Southern Medical Journal
https://www.readbyqxmd.com/read/27911567/recommended-reading-from-mayo-clinic-department-of-pulmonary-and-critical-care-medicine-fellows
#3
Natalya Azadeh, Ryan D Clay, Nicholas A Braus, Kannan Ramar
No abstract text is available yet for this article.
December 2, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27910305/comparison-of-polystyrene-scintillator-fiber-array-and-monolithic-polystyrene-for-neutron-imaging-and-radiography
#4
R Simpson, T E Cutler, C R Danly, M A Espy, J H Goglio, J F Hunter, A C Madden, D R Mayo, F E Merrill, R O Nelson, A L Swift, C H Wilde, T G Zocco
The neutron imaging diagnostic at the National Ignition Facility has been operating since 2011 generating neutron images of deuterium-tritium (DT) implosions at peak compression. The current design features a scintillating fiber array, which allows for high imaging resolution to discern small-scale structure within the implosion. In recent years, it has become clear that additional neutron imaging systems need to be constructed in order to provide 3D reconstructions of the DT source and these additional views need to be on a shorter line of sight...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27908443/a-retrospective-validation-study-of-three-models-to-estimate-the-probability-of-malignancy-in-patients-with-small-pulmonary-nodules-from-a-tertiary-oncology-follow-up-centre
#5
A Talwar, N M Rahman, T Kadir, L C Pickup, F Gleeson
AIM: To estimate the probability of malignancy in small pulmonary nodules (PNs) based on clinical and radiological characteristics in a non-screening population that includes patients with a prior history of malignancy using three validated models. MATERIALS AND METHODS: Retrospective data on clinical and radiological characteristics was collected from the medical records of 702 patients (379 men, 323 women; range 19-94 years) with PNs ≤12 mm in diameter at a single centre...
November 28, 2016: Clinical Radiology
https://www.readbyqxmd.com/read/27908409/evaluation-of-sulfur-isotopic-enrichment-of-urine-metabolites-for-the-differentiation-of-healthy-and-prostate-cancer-mice-after-the-administration-of-34-s-labelled-yeast
#6
Oscar Galilea San Blas, Fernando Moreno Sanz, Pilar Herrero Espílez, Rosa María Sainz Menéndez, Juan Carlos Mayo Barallo, Juan Manuel Marchante-Gayón, José Ignacio García Alonso
Sulfur isotopic enrichment of urine metabolites in healthy and prostate cancer mice using (34)S enriched yeast and High Performance Liquid Chromatography coupled to Multicollector Inductively Coupled Plasma Mass Spectrometry (HPLC-MC-ICP-MS) has been evaluated. A 30 weeks experiment (since the eleventh to the fortieth week of life) was carried out collecting the urine of three healthy mice and three transgenic mice with prostate cancer during 24h after a single oral administration of a (34)S enriched yeast slurry...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908204/clinical-implications-of-serial-versus-isolated-biliary-fluorescence-in-situ-hybridization-fish-polysomy-in-primary-sclerosing-cholangitis
#7
Kevin P Quinn, James H Tabibian, Keith D Lindor
BACKGROUND: Cholangiocarcinoma (CCA) is a leading cause of death in patients with primary sclerosing cholangitis (PSC). Biliary polysomy detected by fluorescence in situ hybridization (FISH) helps to identify patients with early CCA, but not all PSC patients with polysomy develop CCA. Here, we examined the features and clinical outcomes of PSC patients with serial versus isolated polysomy. METHODS: All patients with PSC who underwent ≥1 endoscopic retrograde cholangiography (ERC) with FISH testing at Mayo Clinic, Rochester from 2008-2011 were identified...
December 1, 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27907936/early-treatment-for-neonatal-abstinence-syndrome-a-palliative-approach
#8
Jennifer Hudson, Rachel Mayo, Lori Dickes, Liwei Chen, Windsor Westbrook Sherrill, Julie Summey, Bradley Dalton, Kindal Dankovich
Objective To describe medical, safety, and health care utilization outcomes associated with an early treatment model for neonatal opioid withdrawal. Study Design This is a retrospective review of 117 opioid-exposed infants born in a large regional hospital and treated in the level I nursery with methadone initiated within 48 hours of birth. Results For this cohort, mean length of stay was 8.3 days. Hospital safety events were infrequent; there were no medication errors or deaths. Within 30 days of discharge, 14% of infants visited the emergency department; 7% were readmitted...
December 1, 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27906804/prostaglandin-e-major-urinary-metabolite-as-a-biomarker-for-pediatric-ulcerative-colitis-activity
#9
Shin-Ichiro Hagiwara, Isao Okayasu, Mutsunori Fujiwara, Masaaki Matsuura, Hiromitsu Ohnishi, Satoru Ito, Hiroshi Kishimoto, Ryusuke Nambu, Seiichi Kagimoto
OBJECTIVES: Prostaglandin E-major urinary metabolite (PGE-MUM) is a useful biomarker for adult ulcerative colitis (UC) activity. In this study, we evaluated whether PGE-MUM can also be a biomarker of pediatric UC activity and compared its efficacy in predicting UC activity with that of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). METHODS: Twenty-nine pediatric UC patients (8-18 years) and 29 healthy age- and sex-matched subjects were enrolled...
November 30, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27904798/functional-outcomes-after-distal-biceps-brachii-repair-a-case-series
#10
Christine L Redmond, Tim Morris, Charissa Otto, Tanisha Zerella, John G Semmler, Taaibos Human, Joideep Phadnis, Gregory I Bain
OBJECTIVES: To investigate outcomes after surgical repair of distal biceps tendon rupture and the influence of arm dominance on isokinetic flexion and supination results. BACKGROUND/PURPOSE: While relatively uncommon, rupture of the distal biceps tendon can result in significant strength deficits, for which surgical repair is recommended. The purpose of this study was to assess patient reported functional outcomes and muscle performance following surgery. METHODS: A sample of 23 participants (22 males, 1 female), who had previously undergone surgical repair of the distal biceps tendon, were re-examined at a minimum of one year after surgery...
December 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27904716/is-anterior-bridge-plating-for-mid-shaft-humeral-fractures-a-suitable-option-for-patients-predominantly-involved-in-overhead-activities-a-functional-outcome-study-in-athletes-and-manual-laborers
#11
Abhishek S Mahajan, Young Gun Kim, Jae Hwa Kim, Prashanth D'sa, Azhar Lakhani, Hyun Soo Ok
BACKGROUND: To assess the functional and radiological outcomes of minimally invasive anterior bridge plating (ABP) for mid-shaft humerus fractures in patients predominantly involved in overhead activities (athletes and manual laborers). METHODS: Forty-eight patients fulfilling inclusion criteria were treated with ABP at a level-I trauma center using a 4.5-mm dynamic/locking compression plate and followed for a period of 1 year. Functional outcome was assessed using the Constant, Mayo elbow, and Disabilities of the Arm, Shoulder and Hand (DASH) scores...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27904216/scapholunate-ligament-reconstruction-using-the-palmaris-longus-tendon-and-suture-anchor-fixation-in-chronic-scapholunate-instability
#12
Maulik Jagdish Gandhi, Timothy Paul Knight, Peter John Ratcliffe
BACKGROUND: Multiple reconstruction techniques have been described in the management of chronic scapholunate (SL) instability, either based on the capsulodesis or tenodesis principle. It is uncertain which surgical method produces the best patient outcomes. We describe results of a technique using palmaris longus (PL) tendon for surgical reconstruction of the SL ligament and provide functional outcomes scores. MATERIALS AND METHODS: We surgically reconstructed the SL ligament using a PL tendon graft secured with Mitek(®) bone anchors...
November 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27904213/functional-outcome-of-intraarticular-distal-humerus-fracture-fixation-using-triceps-sparing-paratricipital-approach
#13
Vishal Yadav, Pulak Sharma, Ashish Gohiya
BACKGROUND: Displaced intraarticular distal humerus fracture has been conventionally treated operatively with various triceps disrupting approaches. These approaches are associated with several complications, such as triceps weakness, nonunion or delayed union of osteotomy, implant prominence, and delayed mobilization of the elbow. We present the functional outcome of intraarticular distal humerus fracture fixation using a triceps-sparing paratricipital approach which allows early elbow mobilization and preserving triceps strength...
November 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27902167/arthroscopic-limited-intercarpal-fusion-without-bone-graft-in-patients-with-kienb%C3%A3-ck-s-disease
#14
Kadir Ertem, Gökay Görmeli, Mustafa Karakaplan, Okan Aslantürk, Yunus Karakoç
OBJECTIVES: This study aims to present our clinical results obtained in arthroscopic limited intercarpal fusion performed without using bone graft in patients with Kienböck's disease. PATIENTS AND METHODS: The study included 11 patients with Kienböck's disease (6 males, 5 females; mean age 28.9 years; range 14 to 51 years) who were performed arthroscopic lunate excision and scaphocapitate fusion between November 2012 and December 2013. Bain and Begg Arthroscopic Classification was used for the staging of Kienböck's disease...
December 2016: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/27900711/lacertus-fibrosus-augmentation-for-distal-biceps-brachii-rupture-repair-surgical-technique
#15
M Fontana, A Trimarchi, A Colozza
BACKGROUND: Repair of distal biceps tendon ruptures has become widely accepted. Unfortunately, care of retracted-degenerated injuries remains a challenge for orthopedic surgeons. Complication rates appear to increase when surgery is performed in chronic cases compared to those operated acutely. Multiple techniques for chronic reconstruction with the use of grafts have been described. Recently Morrey, from the Mayo Clinic, proposed a direct anatomic repair of retracted distal biceps tendon ruptures in extreme flexion (60°-90°) to avoid grafting...
December 2016: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/27900709/double-locking-precontoured-plating-system-for-malunited-fractures-of-the-distal-end-of-humerus
#16
L Tarallo, R Mugnai, M Rocchi, C Rovesta, F Catani
BACKGROUND: Distal humeral malunions are uncommon injuries, often associated with limited elbow motion, pain, instability, weakness, and sometimes ulnar neuritis. The complex anatomy of the elbow joint makes this condition one of the most complex elbow injuries to treat. MATERIALS AND METHODS: Four patients were treated by the same surgeon between 2011 and 2013 using a double-locking precontoured plating system for malunited intra-articular or extra-articular fractures of the distal end of the humerus...
December 2016: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/27900699/the-anconeus-triceps-lateral-flap-approach-for-total-elbow-arthroplasty-in-rheumatoid-arthritis
#17
A Celli, P Bonucci
BACKGROUND: The posterior approaches to the elbow are considered as to allow an excellent joint exposure for total elbow arthroplasty. One complication that is well recognized is the insufficiency of the extensor mechanism in particular with the patients with poor tendon quality as in the rheumatoid diseases. The purpose of this paper is to present a new triceps-splitting exposure for total elbow arthroplasty used in rheumatoid patients with their preliminary results. METHODS: Fifteen consecutive patients with rheumatoid disease at grades III to V of the Larsen grading scale underwent total elbow replacement using the new triceps-splitting exposure called anconeus-triceps lateral flap and it preserves the integrity of the medial proper triceps tendon...
December 2016: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/27900307/arthroscopic-fixation-of-coronoid-process-fractures-through-coronoid-tunnelling-and-capsular-plication
#18
Paolo Arrigoni, Riccardo D'Ambrosi, Davide Cucchi, Simone Nicoletti, Enrico Guerra
PURPOSE: the purpose of this study is to describe a new arthroscopic technique for reduction and fixation of coronoid process fractures (CPFs) and report clinical and functional results in 4 patients after a 24-month follow-up. METHODS: four patients underwent arthroscopic reduction and fixation of isolated CPFs (acute or non-unions, type I or type II according to the Regan-Morrey classification) performed using a new technique based on coronoid tunnelling and capsular plication...
July 2016: Joints
https://www.readbyqxmd.com/read/27898163/the-puerto-rico-journal-of-public-health-and-tropical-medicine-1925-1950-from-a-health-department-bulletin-to-a-upr-school-of-tropical-medicine-scientific-journal
#19
Raúl Mayo-Santana
This essay presents a history of the scientific journal of the University of Puerto Rico, School of Tropical Medicine (STM) under the auspices of Columbia University: The Puerto Rico Journal of Public Health and Tropical Medicine. This is the third article in a historical series about the STM, and includes supporting information relevant to the forthcoming articles on the school's scientific endeavors. This article is conceived as a history from the perspective of the literature of journal genre in the field of tropical medicine...
December 2016: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/27898034/emerging-non-canonical-functions-and-regulation-by-p53-p53-and-stemness
#20
REVIEW
David J Olivos, Lindsey D Mayo
Since its discovery nearly 40 years ago, p53 has ascended to the forefront of investigated genes and proteins across diverse research disciplines and is recognized most exclusively for its role in cancer as a tumor suppressor. Levine and Oren (2009) reviewed the evolution of p53 detailing the significant discoveries of each decade since its first report in 1979. In this review, we will highlight the emerging non-canonical functions and regulation of p53 in stem cells. We will focus on general themes shared among p53's functions in non-malignant stem cells and cancer stem-like cells (CSCs) and the influence of p53 on the microenvironment and CSC niche...
November 26, 2016: International Journal of Molecular Sciences
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