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https://www.readbyqxmd.com/read/28636404/examining-the-association-between-health-literacy-and-medication-adherence-among-older-adults
#1
Tilicia L Mayo-Gamble, Charles Mouton
Health literacy plays a vital role in patients' understanding of their prescribed medication instructions. To inform strategies to assist providers in communicating in a manner that is easily understood by patients, it would be beneficial to determine the relationship between health literacy and the day-to-day aspects of medication adherence. This study identified: 1) differences of health literacy levels in medication adherence; 2) the association between health literacy and medication adherence; and 3) and factors associated with medication adherence score...
June 21, 2017: Health Communication
https://www.readbyqxmd.com/read/28634104/natural-language-processing-for-asthma-ascertainment-in-different-practice-settings
#2
Chung-Il Wi, Sunghwan Sohn, Mir Ali, Elizabeth Krusemark, Euijung Ryu, Hongfang Liu, Young J Juhn
BACKGROUND: We developed and validated NLP-PAC, a natural language processing (NLP) algorithm based on predetermined asthma criteria (PAC) for asthma ascertainment using electronic health records at Mayo Clinic. OBJECTIVE: To adapt NLP-PAC in a different health care setting, Sanford Children Hospital, by assessing its external validity. METHODS: The study was designed as a retrospective cohort study that used a random sample of 2011-2012 Sanford Birth cohort (n = 595)...
June 17, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28632737/supervised-filters-for-eeg-signal-in-naturally-occurring-epilepsy-forecasting
#3
Francisco Javier Muñoz-Almaraz, Francisco Zamora-Martínez, Paloma Botella-Rocamora, Juan Pardo
Nearly 1% of the global population has Epilepsy. Forecasting epileptic seizures with an acceptable confidence level, could improve the disease treatment and thus the lifestyle of the people who suffer it. To do that the electroencephalogram (EEG) signal is usually studied through spectral power band filtering, but this paper proposes an alternative novel method of preprocessing the EEG signal based on supervised filters. Such filters have been employed in a machine learning algorithm, such as the K-Nearest Neighbor (KNN), to improve the prediction of seizures...
2017: PloS One
https://www.readbyqxmd.com/read/28632594/outcome-of-early-and-late-diagnosed-essex-lopresti-injury
#4
Marc Schnetzke, Felix Porschke, Karin Hoppe, Stefan Studier-Fischer, Paul-Alfred Gruetzner, Thorsten Guehring
BACKGROUND: The aim of this study was to investigate the outcomes in a large series of Essex-Lopresti injuries (ELIs) and to compare patients with early and late diagnoses. METHODS: Thirty-one patients with an ELI (average age and standard deviation [SD], 46 ± 10 years) who were followed for a minimum of 2 years were included in the study. Patients were grouped according to whether the ELI had been diagnosed early (on the day of the injury) or late (>4 weeks after the radial head injury)...
June 21, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28632405/reading-performance-improvements-in-patients-with-central-vision-loss-without-age-related-macular-degeneration-after-undergoing-personalized-rehabilitation-training
#5
María B Coco-Martín, Alberto López-Miguel, Rubén Cuadrado, Agustín Mayo-Iscar, Azael J Herrero, José C Pastor, Miguel J Maldonado
PURPOSE: To evaluate the efficacy of a reading rehabilitation program (RRP) in patients with central visual loss (CVL) and assess the impact of the RRP on the quality of life (QoL). METHODS: The RRP included four in-office and 39 in-home training sessions over 6 weeks. Reading speed, duration, and font size were evaluated during each in-office session. The subjective perception of the QoL was assessed before and after the RRP using the short version of a questionnaire (World Health Organization Quality of Life)...
June 20, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28630856/chimeric-genes-in-deletions-and-duplications-associated-with-intellectual-disability
#6
Sonia Mayo, Sandra Monfort, Mónica Roselló, Carmen Orellana, Silvestre Oltra, Alfonso Caro-Llopis, Francisco Martínez
We report on three nonrelated patients with intellectual disability and CNVs that give rise to three new chimeric genes. All the genes forming these fusion transcripts may have an important role in central nervous system development and/or in gene expression regulation, and therefore not only their deletion or duplication but also the resulting chimeric gene may contribute to the phenotype of the patients. Deletions and duplications are usually pathogenic when affecting dose-sensitive genes. Alternatively, a chimeric gene may also be pathogenic by different gain-of-function mechanisms that are not restricted to dose-sensitive genes: the emergence of a new polypeptide that combines functional domains from two different genes, the deregulated expression of any coding sequence by the promoter region of a neighboring gene, and/or a putative dominant-negative effect due to the preservation of functional domains of partially truncated proteins...
2017: International Journal of Genomics
https://www.readbyqxmd.com/read/28629914/mortality-risk-prediction-in-scleroderma-related-interstitial-lung-disease-the-sadl-model
#7
Julie Morisset, Eric Vittinghoff, Brett M Elicker, Xiaowen Hu, Stephanie Le, Jay H Ryu, Kirk D Jones, Anna Haemel, Jeffrey A Golden, Francesco Boin, Brett Ley, Paul J Wolters, Talmadge E King, Harold R Collard, Joyce S Lee
RATIONALE: Interstitial lung disease (ILD) is an important cause of morbidity and mortality in scleroderma (Scl). Risk prediction and prognostication in Scl-ILD patients is challenging because of heterogeneity in the disease course. METHODS: We aimed to develop a clinical mortality risk prediction model for Scl-ILD. Patients with Scl-ILD were identified from two ongoing longitudinal cohorts: 135 patients at the University of California, San Francisco (UCSF, derivation cohort) and 90 patients at the Mayo Clinic (validation cohort)...
June 16, 2017: Chest
https://www.readbyqxmd.com/read/28626399/sigmoid-adenocarcinoma-with-regional-scrotal-metastasis
#8
Brenen P Swofford, Tomislav Dragovich
Colorectal cancer is a common disease, representing the third and second most common cause of cancer death in the United States in women and men, respectively. [Ahnen et al.: Mayo Clin Proc 2014;89: 216-224; Siegel et al.: CA Cancer J Clin 2016;66: 7]. It is estimated that 20% of patients have distant metastatic disease at time of diagnosis [Ahnen et al.: Mayo Clin Proc 2014;89: 216-224; Siegel et al.: CA Cancer J Clin 2016;66: 7]. The most common metastatic sites include regional lymph nodes, liver, lungs, and peritoneum via lymphatic/hematogenous dissemination as well as contiguous and transperitoneal routes [Ahnen et al...
May 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28624977/interaction-of-mammographic-breast-density-with-menopausal-status-and-postmenopausal-hormone-use-in-relation-to-the-risk-of-aggressive-breast-cancer-subtypes
#9
Lusine Yaghjyan, Rulla M Tamimi, Kimberly A Bertrand, Christopher G Scott, Matthew R Jensen, V Shane Pankratz, Kathy Brandt, Daniel Visscher, Aaron Norman, Fergus Couch, John Shepherd, Bo Fan, Yunn-Yi Chen, Lin Ma, Andrew H Beck, Steven R Cummings, Karla Kerlikowske, Celine M Vachon
PURPOSE: We examined the associations of mammographic breast density with breast cancer risk by tumor aggressiveness and by menopausal status and current postmenopausal hormone therapy. METHODS: This study included 2596 invasive breast cancer cases and 4059 controls selected from participants of four nested case-control studies within four established cohorts: the Mayo Mammography Health Study, the Nurses' Health Study, Nurses' Health Study II, and San Francisco Mammography Registry...
June 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28624644/psychiatric-symptom-recognition-without-labeled-data-using-distributional-representations-of-phrases-and-on-line-knowledge
#10
Yaoyun Zhang, Olivia Zhang, Yonghui Wu, Hee-Jin Lee, Jun Xu, Hua Xu, Kirk Roberts
OBJECTIVE: Mental health is becoming an increasingly important topic in healthcare. Psychiatric symptoms, which consist of subjective descriptions of the patient's experience, as well as the nature and severity of mental disorders, are critical to support the phenotypic classification for personalized prevention, diagnosis, and intervention of mental disorders. However, few automated approaches have been proposed to extract psychiatric symptoms from clinical text, mainly due to (a) the lack of annotated corpora, which are time-consuming and costly to build, and (b) the inherent linguistic difficulties that symptoms present as they are not well-defined clinical concepts like diseases...
June 14, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28624118/decreasing-patient-stress-and-physician-medical-workforce-burnout-through-health-care-environments-uncovering-the-serious-leisure-perspective-at-mayo-clinic-s-campus-in-rochester-minnesota
#11
REVIEW
Rodney B Dieser, Christopher R Edginton, Renee Ziemer
Health care environments are places of high stress for both patients and medical professionals. Although organizational efforts of workload and efficiency are often implemented to decrease both patient and physician/medical workforce stress, what is often overlooked is how leisure opportunities and programs located in day-to-day experiences and in physically built environments can increase both patient and medical staff enjoyment and pleasure, thus lowering patient stress and physician/medical staff burnout...
June 9, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28622303/addition-of-cyclophosphamide-and-higher-doses-of-dexamethasone-do-not-improve-outcomes-of-patients-with-al-amyloidosis-treated-with-bortezomib
#12
E Kastritis, M Gavriatopoulou, M Roussou, D Fotiou, D C Ziogas, M Migkou, E Eleutherakis-Papaiakovou, I Panagiotidis, N Kanellias, E Psimenou, E Papadopoulou, C Pamboucas, E Manios, H Gakiopoulou, A Ntalianis, A Tasidou, S Giannouli, E Terpos, M A Dimopoulos
Bortezomib, in combination with dexamethasone (VD) or with the addition of cyclophosphamide (VCD), is highly effective in patients with amyloid light-chain (AL) amyloidosis. Currently, VCD is considered as a primary regimen for patients with AL, but it is not clear whether the addition of cyclophosphamide to VD further and significantly improves efficacy, given the substantial activity of bortezomib itself. We retrospectively compared the outcomes of 101 patients with AL amyloidosis who received VD (n=59) or VCD (n=42) in two consecutive periods...
June 16, 2017: Blood Cancer Journal
https://www.readbyqxmd.com/read/28622181/validation-of-a-mitotic-index-cutoff-as-a-prognostic-marker-in-undifferentiated-uterine-sarcomas
#13
Elin Hardell, Sofia Josefson, Mehran Ghaderi, Tone Skeie-Jensen, Sofia Westbom-Fremer, Elizabeth H Cheek, Debra Bell, Jonas Selling, John K Schoolmeester, Anna Måsbäck, Ben Davidson, Joseph W Carlson
Undifferentiated uterine sarcomas (UUS) are a heterogenous group of high-grade mesenchymal tumors. Although these tumors are highly aggressive, a subset of patients may experience long-term survival. These tumors have previously been divided morphologically into uniform and pleomorphic types. A previous study demonstrated that a mitotic index cutoff of 25 mitoses/10 high-power fields (corresponding to 11.16 mitotic figures/mm) could successfully divide tumors into 2 prognostic groups with significantly different overall survival...
June 15, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28622153/extraskeletal-osteosarcoma-outcomes-and-the-role-of-chemotherapy
#14
Jonas Paludo, Karen Fritchie, Candace L Haddox, Peter S Rose, Carola A S Arndt, Randolph S Marks, Evanthia Galanis, Scott H Okuno, Steven I Robinson
OBJECTIVES: Extraskeletal osteosarcoma (EO) is a malignant neoplasm that produces osteoid, bone, and chondroid material without direct attachment to bone or periosteum. Surgical resection is the mainstay of treatment; the role of chemotherapy is not well defined. Therefore, we evaluated the impact of chemotherapy in the survival of patients with EO. METHODS: All EO patients seen at Mayo Clinic between 1990 and 2014 were assessed. Forty-three patients were included after all archived pathology slides were reviewed to confirm the diagnosis of EO...
June 15, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28617729/demographic-characteristics-and-prescribing-patterns-of-scleral-lens-fitters-the-scope-study
#15
Cherie B Nau, Jennifer Harthan, Ellen Shorter, Joseph Barr, Amy Nau, Nicolette T Chimato, David O Hodge, Muriel M Schornack
OBJECTIVES: This study reports demographic characteristics of scleral lens providers and indications for scleral lens prescription as assessed by a worldwide online survey. METHODS: The Scleral Lenses in Current Ophthalmic Practice: an Evaluation (SCOPE) study group designed the online survey regarding current scleral lens prescription and management practices. The Mayo Clinic Survey Research Center administered the survey, which was open from January 15 to March 31, 2015...
June 14, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28617721/analysis-of-a-physician-led-team-based-care-model-for-the-treatment-of-glaucoma
#16
Nelson S Winkler, Gena M Damento, Sunil S Khanna, David O Hodge, Cheryl L Khanna
PURPOSE: To determine the effect of a protocol for a new physician-led, team-based glaucoma care model implemented in 2008 at Mayo Clinic's campus in Rochester, Minnesota (MCR), to increase conformance with the American Academy of Ophthalmology (AAO) Preferred Practice Pattern guidelines for treatment of primary open-angle glaucoma. METHODS: Records of 591 patients with newly diagnosed glaucoma were assessed retrospectively for the completion of 9 AAO Preferred Practice Pattern recommended metrics including measured corneal thickness, intraocular pressure (IOP), cup to disk ratio, visual acuity, recorded IOP target, gonioscopy, fundus photos, ocular coherence tomography, and visual field in the 3 years before and 3 years after protocol implementation...
June 14, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28617181/a-novel-surgical-approach-for-treating-distal-radial-extraarticular-malunion-oblique-osteotomy-with-buttress-plate-stabilization
#17
Chi-Chuan Wu
PURPOSE: Distal radial extraarticular malunions are not uncommon. However, requirements of surgical correction depend on multiple conditions. Traditionally, surgical techniques include closing or opening wedge osteotomies. Each has unique advantages and disadvantages. An oblique osteotomy was developed to simplify the revision surgery. METHODS: Forty-eight consecutive adult patients with 48 malunions were surgically treated. An oblique osteotomy of 45° vertical to the radial longitudinal axis was performed from medio-distally to latero-proximally...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28616779/-arthrodesis-of-the-distal-interphalangeal-joint-using-the-headless-compression-screw
#18
REVIEW
C K Spies, B Hohendorff, S Löw, L P Müller, J Oppermann, P Hahn, F Unglaub
OBJECTIVE: Arthrodesis of the distal interphalangeal joint of the fingers and interphalangeal joint of the thumb in order to gain reliable stability and function. INDICATIONS: Primary and secondary osteoarthritis, rheumatoid arthritis, defect lesions, septic joint destruction, posttraumatic joint deviation, fatal joint instability, fatal tendon lesions. CONTRAINDICATIONS: Persistent infections (empyema, osteomyelitis, phlegmon), deficient soft tissue mantle, bone/screw mismatch...
June 14, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28616731/renal-nerve-stimulation-for-treatment-of-neurocardiogenic-syncope-a-review-from-perspective-of-commercialization-potential
#19
REVIEW
B O'Brien, H Zafar, F Sharif
A strong evidence of outcomes for vasovagal syncope is not easily identified. It would seem reasonable that the proposed Mayo Clinic technology would be reserved for cases with severe recurrent or refractory syncope. However, recurrence levels are relatively low, and while some predictive methods have been proposed, recurrence is also influenced by the interaction that occurs during screening and examinations, i.e. recurrence diminishes once an initial diagnosis has been made. Finally, a key factor in being able to identify suitable patients relates to understanding the relative significance of the vasodepression and cardioinhibitory components-the therapy is best suited to patients that have a significant level of both components...
June 14, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28616546/late-gadolinium-enhancement-does-occur-in-tako-tsubo-cardiomyopathy-a-quantitative-cardiac-magnetic-resonance-and-speckle-tracking-strain-study
#20
Niranjan Gaikwad, Thomas Butler, Ryan Maxwell, Elizabeth Shaw, Wendy E Strugnell, Jonathan Chan, Gemma A Figtree, Richard E Slaughter, Christian Hamilton-Craig
BACKGROUND: Late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) has been recommended to distinguish Tako-tsubo cardiomyopathy (TTC) from either acute myocardial infarction or myocarditis. METHOD: 44 consecutive patients with confirmed Mayo Clinic criteria for TTC underwent CMR imaging at 1.5 Tesla during the acute phase. 10 patients who had CMRI to exclude scar related ventricular tachycardia, and had negative studies, were used as negative controls...
September 2016: IJC Heart & Vasculature
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