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https://www.readbyqxmd.com/read/29770431/outcome-in-lacunar-stroke-a-cohort-study
#1
V Mantero, C Scaccabarozzi, E Botto, G Giussani, A Aliprandi, A Lunghi, E Ciusani, G Brenna, A Salmaggi
OBJECTIVES: We evaluated a prospective cohort of 150 patients under observation in our centre for lacunar strokes. The purpose of this study was to evaluate the outcome at time of discharge and 6 months after lacunar stroke, as well as the correlation with cardiovascular risk factors and selected biochemical parameters already evaluated on admission. Focus was to identify possible prognostic factors, which might be targeted through appropriate intervention concentrating on reduction in the incidence and impact of early clinical deterioration...
May 16, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29760843/multicenter-study-of-albuterol-use-among-infants-hospitalized-with-bronchiolitis
#2
Anna Condella, Jonathan M Mansbach, Kohei Hasegawa, Peter S Dayan, Ashley F Sullivan, Janice A Espinola, Carlos A Camargo
Introduction: Although bronchiolitis is a common reason for infant hospitalization, significant heterogeneity persists in its management. The American Academy of Pediatrics currently recommends that inhaled albuterol not be used in routine care of children with bronchiolitis. Our objective was to identify factors associated with pre-admission (e.g., emergency department or primary care) use of albuterol among infants hospitalized for bronchiolitis. Methods: We analyzed data from a 17-center observational study of 1,016 infants (age <1 year) hospitalized with bronchiolitis between 2011-2014...
May 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29758586/opioid-intake-prior-to-admission-is-not-increased-in-elderly-patients-with-low-energy-fractures-a-case-control-study-in-a-german-hospital-population
#3
A Schwarzer, M Kaisler, K Kipping, D Seybold, V Rausch, C Maier, J Vollert
BACKGROUND: Recent studies revealed an increased prescription rate of opioids for elderly patients suffering bone fractures. To gain further insight, we conducted face-to-face interviews in the present study to compare the opioid intake between patients with low energy fractures and patients suffering from internal diseases. METHODS: In this case-control study, 992 patients, aged 60 years and older, were enrolled between March 2014 and February 2015. The interview comprised a fall and medication history, comorbidities, mobility and other risk factors for fractures...
May 14, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29756498/construct-validity-and-inter-rater-reliability-of-the-dutch-activity-measure-for-post-acute-care-6-clicks-basic-mobility-form-to-assess-the-mobility-of-hospitalized-patients
#4
Sven Jacobus Gertruda Geelen, Karin Valkenet, Cindy Veenhof
To evaluate the construct validity and the inter-rater reliability of the Dutch Activity Measure for Post-Acute Care "6-clicks" Basic Mobility short form measuring the patient's mobility in Dutch hospital care. First, the "6-clicks" was translated by using a forward-backward translation protocol. Next, 64 patients were assessed by the physiotherapist to determine the validity while being admitted to the Internal Medicine wards of a university medical center. Six hypotheses were tested regarding the construct "mobility" which showed that: Better "6-clicks" scores were related to less restrictive pre-admission living situations (p = 0...
May 12, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29705118/multi-stakeholder-informed-guidelines-for-direct-admission-of-children-to-hospital
#5
JoAnna K Leyenaar, Megan Shevenell, Paul A Rizzo, Vanessa L Hill, Peter K Lindenauer
OBJECTIVES: To develop pediatric direct admission guidelines and prioritize outcomes to evaluate the safety and effectiveness of hospital admission processes. STUDY DESIGN: We conducted deliberative discussions at 1 children's hospital and 2 community hospitals, engaging parents of hospitalized children and inpatient, outpatient, and emergency department physicians and nurses to identify shared and dissenting perspectives regarding direct admission processes and outcomes...
April 25, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29678257/-functional-status-as-an-independent-risk-factor-in-elderly-patients-admitted-to-an-intensive-care-unit
#6
Federico Gordo, Cristina Castro, Inés Torrejón, Sonia Bartolomé, Francisco Coca, Ana Abella
OBJECTIVE: To assess the association of previous functional status in elderly patients admitted to the ICU, estimated by the Barthel and Short Form-Late Life Function and Disability instrument scales, and the relationship with prognosis and functional capacity at hospital discharge. MATERIAL AND METHODS: Observational prospective study of ICU-admitted patients older than 74 years, with a length of stay greater than 48hours. Demographic data, social background, comorbidities, disability questionnaire (Barthel, Short Form-Late Life Function and Disability instrument), main diagnosis and severity (SAPS 3) on ICU admission were recorded...
April 17, 2018: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/29671705/explicit-versus-implicit-evaluation-to-detect-inappropriate-medication-use-in-geriatric-outpatients
#7
Gulistan Bahat, Birkan Ilhan, Ilker Bay, Cihan Kilic, Pinar Kucukdagli, Meryem Merve Oren, Mehmet Akif Karan
AIM: The rates and reasons why clinicians decide not to follow recommendations from explicit-criteria have been studied scarce. We aimed to compare STOPP version 2 representing one of the most commonly used excplicit tool with the implicit comprehensive geriatric assessment mediated clinical evaluation considered as gold standard. METHODS: Two hundred and six (n = 206) outpatients ≥65 years old were included. The study was designed as retrospective, cross-sectional, and randomised...
April 19, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29624189/improving-the-safety-of-opioid-use-for-acute-noncancer-pain-in-hospitalized-adults-a-consensus-statement-from-the-society-of-hospital-medicine
#8
Shoshana J Herzig, Hilary J Mosher, Susan L Calcaterra, Anupam B Jena, Teryl K Nuckols
Hospital-based clinicians frequently treat acute, noncancer pain. Although opioids may be beneficial in this setting, the benefits must be balanced with the risks of adverse events, including inadvertent overdose and prolonged opioid use, physical dependence, or development of opioid use disorder. In an era of epidemic opioid use and related harms, the Society of Hospital Medicine (SHM) convened a working group to develop a consensus statement on opioid use for adults hospitalized with acute, noncancer pain, outside of the palliative, end-of-life, and intensive care settings...
April 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29620476/association-of-pre-admission-statin-therapy-and-the-inflammatory-response-in-st-elevation-myocardial-infarction-patients
#9
Zach Rozenbaum, Dor Ravid, Gilad Margolis, Shafik Khoury, Natalia Kaufman, Gad Keren, Assi Milwidsky, Yacov Shacham
PURPOSE: To demonstrate the possible association of statin therapy with C reactive protein (CRP) serial measurements in ST elevation myocardial infarction (STEMI) patients. MATERIALS AND METHODS: STEMI patients between 2008 and 2016 with available CRP data from admission were divided into two groups according to pre-admission statin therapy. A second CRP measurement was noted following primary coronary intervention (within 24 hours from admission). The difference between the two measurements was designated ΔCRP...
April 5, 2018: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/29606661/relationship-between-dental-students-pre-admission-record-and-performance-on-the-comprehensive-basic-science-examination
#10
Kevin C Lee, Victor Y Lee, Laureen A Zubiaurre, John T Grbic, Sidney B Eisig
The Comprehensive Basic Science Examination (CBSE) is the entrance examination for oral and maxillofacial surgery, but its implementation among dental students is a relatively recent and unintended use. The aim of this study was to examine the relationship between pre-admission data and performance on the CBSE for dental students at the Columbia University College of Dental Medicine (CDM). This study followed a retrospective cohort, examining data for the CDM Classes of 2014-19. Data collected were Dental Admission Test (DAT) and CBSE scores and undergraduate GPAs for 49 CDM students who took the CBSE from September 2013 to July 2016...
April 2018: Journal of Dental Education
https://www.readbyqxmd.com/read/29606659/rethinking-dental-school-admission-criteria-correlation-between-pre-admission-variables-and-first-year-performance-for-six-classes-at-one-dental-school
#11
Kevin C Rowland, Susan Rieken
Admissions committees in dental schools are charged with the responsibility of selecting candidates who will succeed in school and become successful members of the profession. Identifying students who will have academic difficulty is challenging. The aim of this study was to determine the predictive value of pre-admission variables for the first-year performance of six classes at one U.S. dental school. The authors hypothesized that the variables undergraduate grade point average (GPA), undergraduate science GPA (biology, chemistry, and physics), and Dental Admission Test (DAT) scores would predict the level of performance achieved in the first year of dental school, measured by year-end GPA...
April 2018: Journal of Dental Education
https://www.readbyqxmd.com/read/29597211/associations-between-pre-admission-risk-scores-and-two-year-clinical-outcomes-in-ischemic-stroke-or-transient-ischemic-attack-patients-with-non-valvular-atrial-fibrillation
#12
Keisuke Tokunaga, Hiroshi Yamagami, Masatoshi Koga, Kenichi Todo, Kazumi Kimura, Ryo Itabashi, Tadashi Terasaki, Yoshiaki Shiokawa, Kenji Kamiyama, Shunya Takizawa, Satoshi Okuda, Yasushi Okada, Tomoaki Kameda, Yoshinari Nagakane, Yasuhiro Hasegawa, Satoshi Shibuya, Yasuhiro Ito, Hideki Matsuoka, Kazuhiro Takamatsu, Kazutoshi Nishiyama, Kazuomi Kario, Yoshiki Yagita, Takanari Kitazono, Naoto Kinoshita, Junji Takasugi, Takuya Okata, Sohei Yoshimura, Shoichiro Sato, Shoji Arihiro, Kazunori Toyoda
BACKGROUND: We aimed to clarify associations between pre-admission risk scores (CHADS2, CHA2DS2-VASc, and HAS-BLED) and 2-year clinical outcomes in ischemic stroke or transient ischemic attack (TIA) patients with non-valvular atrial fibrillation (NVAF) using a prospective, multicenter, observational registry. METHODS: From 18 Japanese stroke centers, ischemic stroke or TIA patients with NVAF hospitalized within 7 days after onset were enrolled. Outcome measures were defined as death/disability (modified Rankin Scale score ≥3) at 2 years, 2-year mortality, and ischemic or hemorrhagic events within 2 years...
March 29, 2018: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29593979/the-association-between-pre-hospital-antibiotic-therapy-and-subsequent-in-hospital-mortality-in-adults-presenting-with-community-acquired-pneumonia-an-observational-study
#13
Biswajit Chakrabarti, Dan Wootton, Steven Lane, Elizabeth Kanwar, Joseph Somers, Jacyln Proctor, Nancy Prospero, Mark Woodhead
Background: The majority of patients with community acquired-pneumonia (CAP) are treated in primary care and the mortality in this group is very low. However, a small but significant proportion of patients who begin treatment in the community subsequently require admission due to symptomatic deterioration. This study compared patients who received community antibiotics prior to admission to those who had not, and looked for associations with clinical outcomes. Methods: This study analysed the Advancing Quality (AQ) Pneumonia database of patients admitted with CAP to 9 acute hospitals in the northwest of England over a 12-month period...
2018: Pneumonia
https://www.readbyqxmd.com/read/29593357/patterns-of-acute-bilirubin-encephalopathy-in-nigeria-a-multicenter-pre-intervention-study
#14
Udochukwu M Diala, Richard P Wennberg, Isa Abdulkadir, Zubaida L Farouk, Carlos D Coda Zabetta, Efe Omoyibo, Abieyuwa Emokpae, Aleksandr Aravkin, Bose Toma, Stephen Oguche, Tina Slusher
BACKGROUND: Acute bilirubin encephalopathy (ABE) is an important cause of neonatal morbidity in Nigeria, accounting for 5-14% of neonatal deaths. Most newborns with severe ABE have irreversible damage before receiving treatment emphasizing the need for timely pre-admission monitoring and referral. There is limited evidence that educational interventions targeting mothers and health care providers will reduce delayed care. OBJECTIVE: To provide baseline data on the incidence of ABE and associated pre-admission risk factors in five centers of Nigeria in order to evaluate the effect of subsequent educational interventions on outcome...
March 28, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29561942/impact-of-mechanical-ventilation-on-quality-of-life-and-functional-status-after-icu-discharge-a-cross-sectional-study
#15
Patrini Silveira Vesz, Rafael Viegas Cremonese, Regis Goulart Rosa, Juçara Gasparetto Maccari, Cassiano Teixeira
OBJECTIVE: To evaluate the impact of the need for mechanical ventilation (MV) and its duration throughout ICU stay on the quality of life (QoL) and physical functional status (PFS) after the immediate ICU discharge. METHOD: This was a cross-sectional study including all subjects consecutively discharged from the ICU during 1-year period. During the first week after ICU discharge, QoL was assessed through WHOQoL-Bref questionnaire and PFS through the Karnofsky Performance Status and modified-Barthel index, and retrospectively compared with the pre-admission status (variation [Δ] of indexes)...
January 2018: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29527296/management-of-eight-labor-and-delivery-patients-dependent-on-buprenorphine-subutex%C3%A2-a-retrospective-chart-review
#16
Solina Tith, Garinder Bining, Laurent Bollag
Background : Opioid use during pregnancy is a growing concern in the United States. Buprenorphine has been recommended by "The American College of Obstetrics and Gynecology" as an alternative to methadone to decrease risks associated with the use of illicit opioids during pregnancy. The partial μ-opioid agonists' unique pharmacology, including its long half time and high affinity to the μ-opioid receptor, complicates patient management in a highly kinetic, and often urgent field like obstetric anesthesia...
2018: F1000Research
https://www.readbyqxmd.com/read/29520943/pre-admission-treatment-with-beta-blockers-in-hypertensive-patients-with-acute-stroke-and-3-month-outcome-data-from-a-national-stroke-registry
#17
Yoav Eizenberg, Ehud Grossman, David Tanne, Silvia Koton
The impact of beta-blockers (BB) treatment on stroke outcome is unclear. We used data from a prospective national stroke registry to assess the associations between use of BB and poor outcome 3 months after stroke. Using the National Acute Stroke Israeli (NASIS) registry, we identified 1126 patients with ischemic stroke and intracerebral hemorrhage with pre-stroke hypertension treatment, who were followed for 3-months. Functional outcome and mortality at 3-month were compared by use of BB, adjusting for demographics and clinical factors...
March 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29499639/polypharmacy-in-the-oldest-old-%C3%A2-80-years-of-age-patients-in-china-a-cross-sectional-study
#18
Xiaoxing Lai, Hongwei Zhu, Xiaopeng Huo, Zheng Li
BACKGROUND: The oldest old generally have worse health and more comorbidities than the general population of older adults, and they are more likely to be exposed to polypharmacy. Reliable investigation of polypharmacy among the oldest old (≥80 years of age) in China are lacking. So this study aims to describe the polypharmacy status of oldest old patients ≥80 years of age and to assess the factors influencing medication compliance. METHODS: This was a cross-sectional study of 258 oldest old patients ≥ 80 years of age and hospitalized at a tertiary hospital in Beijing between December 1, 2014 and June 30, 2015...
March 2, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29485294/delayed-intracranial-hemorrhage-in-the-patient-with-blunt-trauma-on-anticoagulant-or-antiplatelet-agents-routine-repeat-head-computed-tomography-is-unnecessary
#19
Joshua H Hill, Paul Bonner, M Shay O'Mara, Teresa Wood, Michael Lieber
OBJECTIVE: We postulate that in patients with blunt trauma on anticoagulant or antiplatelet agents, incidence and complication rate of delayed intracranial hemorrhage (DICH) after an initially negative head CT is low and routine repeat head CT is not warranted. DESIGN: A retrospective, observational study performed from 2008 to 2012. PATIENTS: A total of 338 patients with blunt trauma with pre-admission history of any anticoagulant use, who had an initially negative head CT, followed by a repeat CT within 48 hours...
2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29482333/understanding-experiences-of-the-self-harm-of-others-a-qualitative-exploration-of-the-views-of-young-people-with-complex-mental-health-needs
#20
Claire Smith-Gowling, Susan F Knowles, Suzanne Hodge
As adolescent self-harm is a growing public health concern, more research is needed to identify potential risk factors. Studies have highlighted that exposure to the self-harm of others may be a risk factor associated with engagement in self-harm. However, research investigating young people's experiences of the self-harm of others has been limited. This qualitative study aimed to explore young people's experiences of the self-harm of others and interviewed a total of eight young people (five females and three males; aged between 13 and 18 years) resident at one of two adolescent mental health inpatient units in the North of England...
February 1, 2018: Clinical Child Psychology and Psychiatry
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