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https://www.readbyqxmd.com/read/29668026/nicu-graduates-the-role-of-the-allied-health-team-in-follow-up
#1
Jane L Orton, Joy E Olsen, Katherine Ong, Rochelle Lester, Alicia J Spittle
Infants who graduate from the neonatal intensive care unit, including those infants born preterm and/or with brain injury, are at increased risk of long-term neurodevelopmental impairments. The developmental allied health team, consisting of physical therapy, occupational therapy, and speech pathology, is crucial in early evaluation of gross motor, fine motor, feeding, and language development. Surveillance of neurodevelopment in the first year of life is essential to ensure early detection of specific developmental delays and impairments, and to ensure timely referral for early intervention...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29668024/nutrition-considerations-after-nicu-discharge
#2
Taylor Peters, Cecelia Pompeii-Wolfe
Preterm infants are at high nutrition risk during neonatal intensive care and well after discharge. Nutrition care should be individualized and provided by a multidisciplinary team including a dietitian. Breast milk, the gold standard for feeding, may not meet the increased needs of preterm infants and may require fortification or supplementation. Decisions regarding formula choice and calorie concentration can also be challenging and require individualization based on growth, intake, and individual need. Developmental milestones should be considered during the initation of complementary food...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29668022/follow-up-care-for-high-risk-preterm-infants
#3
Stephannie M B Voller
Preterm infants continue to have complex medical and developmental issues after discharge from the neonatal intensive care unit. Over the past few decades there has been an increase in preterm births and a decrease in preterm mortality. Many infants are referred to follow-up clinics that specialize in neurodevelopmental assessment. Often, a community pediatrician or family practitioner provides both the medical management and observes developmental milestones of the high-risk neonate. Intense medical management, early identification of delay, and referral for developmental services may improve preterm infant outcomes...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29666787/cardiac-output-monitoring-in-preterm-infants
#4
REVIEW
Matthew McGovern, Jan Miletin
Maintaining optimal circulatory status is a key component of preterm neonatal care. Low-cardiac output (CO) in the preterm neonate leads to inadequate perfusion of vital organs and has been linked to a variety of adverse outcomes with heightened acute morbidity and mortality and adverse neurodevelopmental outcomes. Having technology available to monitor CO allows us to detect low-output states and potentially intervene to mitigate the unwanted effects of reduced organ perfusion. There are many technologies available for the monitoring of CO in the preterm neonatal population and while many act as useful adjuncts to aid clinical decision-making no technique is perfect...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29666163/neurodevelopmental-impairment-among-extremely-preterm-infants-in-the-neonatal-research-network
#5
Ira Adams-Chapman, Roy J Heyne, Sara B DeMauro, Andrea F Duncan, Susan R Hintz, Athina Pappas, Betty R Vohr, Scott A McDonald, Abhik Das, Jamie E Newman, Rosemary D Higgins
OBJECTIVES: Evaluate the spectrum of neurodevelopmental outcome in a contemporary cohort of extremely preterm infants. We hypothesize that the rate of severe neurodevelopmental impairment (NDI) decreases over time. METHODS: Retrospective analysis of neurodevelopmental outcome of preterm infants ≤27 weeks' gestational age (GA) from a Neonatal Research Network center that completed neurodevelopmental follow-up assessments between April 1, 2011, and January 1, 2015...
April 17, 2018: Pediatrics
https://www.readbyqxmd.com/read/29666098/a-misplaced-peripherally-inserted-central-catheter-presenting-as-contralateral-pleural-effusion
#6
Jogender Kumar, Sudeep K C, Kanya Mukhopadhyay, Somosri Ray
A preterm neonate born at 27 weeks, with a birth weight of 555 g, was on continuous positive airway pressure (CPAP) for apnoea of prematurity and initially received total parenteral nutrition (TPN) through the umbilical venous catheter. Peripherally inserted central catheter (PICC) was inserted in the left basilica vein on day 8 to continue TPN. The baby developed respiratory distress with persistent hypoxia after TPN was initiated through the PICC line. The baby required mechanical ventilation due to worsening of respiratory distress, and chest X-ray, as well as ultrasound conducted 12 hours, postinfusion of TPN revealed right-sided pleural effusion...
April 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29664051/predictive-value-of-cranial-ultrasound-for-neurodevelopmental-outcomes-of-very-preterm-infants-with-brain-injury
#7
Xue-Hua Zhang, Shi-Jun Qiu, Wen-Juan Chen, Xi-Rong Gao, Ya Li, Jing Cao, Jing-Jing Zhang
Background: Compared with full-term infants, very preterm infants are more vulnerable to injury and long-term disability and are at high risk of death. The predictive value of ultrasound and imaging on the neurodevelopment is one of the hot topics. This study aimed to investigate the relationship between cranial ultrasound (cUS) variables and neurodevelopmental outcomes of very preterm infants. Methods: Totally 129 very preterm infants (gestational age ≤28 weeks) in neonatal intensive care unit of Hunan Children's Hospital between January 2012 and November 2014 were included in this retrospective study...
April 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29664021/a-tlr-akt-foxo3-immune-tolerance-like-pathway-disrupts-the-repair-capacity-of-oligodendrocyte-progenitors
#8
Taasin Srivastava, Parham Diba, Justin M Dean, Fatima Banine, Daniel Shaver, Matthew Hagen, Xi Gong, Weiping Su, Ben Emery, Daniel L Marks, Edward N Harris, Bruce Baggenstoss, Paul H Weigel, Larry S Sherman, Stephen A Back
Cerebral white matter injury (WMI) persistently disrupts myelin regeneration by oligodendrocyte progenitor cells (OPCs). We identified a specific bioactive hyaluronan fragment (bHAf) that downregulates myelin gene expression and chronically blocks OPC maturation and myelination via a tolerance-like mechanism that dysregulates pro-myelination signaling via AKT. Desensitization of AKT occurs via TLR4 but not TLR2 or CD44. OPC differentiation was selectively blocked by bHAf in a maturation-dependent fashion at the late OPC (preOL) stage by a noncanonical TLR4/TRIF pathway that induced persistent activation of the FoxO3 transcription factor downstream of AKT...
April 16, 2018: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29662967/maternal-serum-uric-acid-level-and-maternal-and-neonatal-complications-in-preeclamptic-women-a-cross-sectional-study
#9
Maryam Asgharnia, Fariba Mirblouk, Soudabeh Kazemi, Davood Pourmarzi, Mina Mahdipour Keivani, Seyedeh Fatemeh Dalil Heirati
Background: Preeclampsia is associated with maternal and neonatal complications. It has been indicated that increased uric acid might have a predictive role on preeclampsia. Objective: We aimed to investigate the relationship between the level of uric acid with maternal and neonatal complications in women with preeclampsia. Materials and Methods: In this cross-sectional study, 160 singleton preeclamptic women at more than 28 wk gestational age were included...
September 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29662731/intraventricular-haemorrhage-complicated-by-hydrocephalus-in-an-acutely-encephalopathic-preterm-infant
#10
Kene Maduemem, Sameen Khalid, Maya Hariharan, Aamer Siddique
Intraventricular haemorrhage (IVH) is characterized by bleeding of the immature subependymal germinal matrix in preterm infants, but the pathogenesis is multifactorial. IVH and posthaemorrhagic hydrocephalus (PHH) are common causes of neonatal morbidity and mortality among preterm infants. We describe a preterm male infant who was born clinically stillbirth; became moderately severe encephalopathic. He had bilateral IVH (III right and IV left) with consequent PHH. His incredible outcome following a stormy perinatal period appears intriguing...
February 15, 2018: Curēus
https://www.readbyqxmd.com/read/29662257/17-hydroxiprogesterone-values-in-healthy-preterm-infants
#11
Víctor Clemente Mendoza-Rojas, Luis Alfonso Díaz-Martínez, Gerardo Mantilla-Mora, Gustavo Adolfo Contreras-García, Víctor Manuel Mora-Bautista, Jhon Freddy Martínez-Paredes, Alba Luz Calderón-Rojas, Carlos Augusto Gómez-Tarazona, Katherine Pinzón-Mantilla
Introduction: In preterm newborn, problems with the interpretation of 17-OHP may occur. Objective: Evaluate 17-OHP values in healthy preterm newborns until they reach the corrected gestational age. Methods: Longitudinal study of 36 preterm infants with 17-OHP evaluation using ELISA from heel blood from 3 to 5 days and thereafter every 2 weeks until the corrected gestational age. Values adjusting multiple variables such as gestational age, birth weight and sex, among others were compared...
December 30, 2017: Colombia Médica: CM
https://www.readbyqxmd.com/read/29660833/selenium-deficiency-and-pregnancy-outcome-in-pregnant-women-with-hiv-in-lagos-nigeria
#12
Kehinde S Okunade, Olusola F Olowoselu, Gbemisola E Osanyin, Sarah John-Olabode, Sulaimon A Akanmu, Rose I Anorlu
OBJECTIVE: To investigate the prevalence of maternal selenium deficiency and its effects on pregnancy outcomes in pregnant women with HIV in Lagos, Nigeria. METHODS: The present descriptive cross-sectional study enrolled women aged 15-49 years with HIV who were at 14-26 weeks of a singleton pregnancy and were attending Lagos University Teaching Hospital, Lagos, Nigeria, between August 1, 2016, and April 30, 2017. Participants were selected by consecutive sampling and baseline data were collected through interviews...
April 16, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29660574/the-effectiveness-of-learning-portfolios-in-learning-participation-and-learners-perceptions-of-skills-and-confidence-in-the-mother-of-preterm-infant
#13
Yi-Chuan Cheng, Li-Li Chen, Yu-Shan Chang, Tsai-Chung Li, Ching-Ju Chen, Li-Chi Huang
OBJECTIVE: The purpose of this study was to investigate the effectiveness of preterm infant learning portfolios in enabling mothers to develop infant care knowledge and skills, as well as confidence in their abilities. DESIGN: This study used a quasi-experimental design. SETTING AND PARTICIPANTS: The sample consisted of 52 mothers with preterm infants recruited at a neonatal intermediate unit of a medical centre in central Taiwan. Among those, 26 participants in the control group received regular health education and 26 participants in the experimental group received learning portfolios and regular care...
March 22, 2018: Midwifery
https://www.readbyqxmd.com/read/29660361/maternal-and-fetal-outcome-after-cardiac-surgery-during-pregnancy-a-meta-analysis
#14
REVIEW
Nivedita Jha, Ajay Kumar Jha, Ramesh Chand Chauhan, Neelima Singh Chauhan
BACKGROUND: In the past, cardiac surgery during pregnancy has been associated with high risk of adverse maternal and fetal outcomes. Therefore, this meta-analysis was done to assess the fetomaternal risk after cardiac surgery during pregnancy using cardiopulmonary bypass in more recent studies. METHODS: The Medline, Embase and Cochrane library were searched to find studies from January 1 1990 to July 31 2016 without language restriction. We selected studies that included at least four women to report fetomaternal outcomes after cardiac surgery using cardiopulmonary bypass during pregnancy...
April 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29660299/infection-induced-thrombin-production-a-potential-novel-mechanism-for-preterm-premature-rupture-of-membranes-pprom
#15
Liping Feng, Terrence K Allen, William P Marinello, Amy P Murtha
BACKGROUND: Preterm premature rupture of membranes (PPROM) is a leading contributor to maternal and neonatal morbidity and mortality. Epidemiologic and experimental studies have demonstrated that thrombin causes fetal membrane weakening and subsequently PPROM. Although blood is suspected as the likely source of thrombin in fetal membranes and amniotic fluid of patients with PPROM, this has not been proven. Ureaplasma Parvum (U. parvum) is emerging as a pathogen involved in prematurity, including PPROM, but until now, prothrombin production directly induced by bacteria in fetal membranes has not been described...
April 13, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29658461/-monitoring-of-kidney-injury-in-preterm-infants
#16
Rong Zhang, Wen-Bin Dong
Acute kidney injury (AKI) is a common complication in the neonatal intensive care unit that causes a high mortality of preterm infants and various chronic kidney diseases in adulthood. Preterm infants have immature development of the kidneys at birth. The kidneys continue to develop within a specific time window after birth. However, due to various factors during pregnancy and after birth, preterm infants tend to develop AKI. At present, serum creatinine and urine volume are used for the assessment of kidney injury, and their early sensitivity and specificity have attracted increasing attention...
April 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29658450/-influence-of-acute-pancreatitis-in-pregnancy-on-pregnancy-outcomes-and-neonates
#17
Shu-Juan Fan, Jun-Xi Xiang, Mi Xiao, Fang-Hui Wang, Xiao-Jie Lin, Xi-Hui Zhou, Ting Ai, Li Liu
OBJECTIVE: To study the influence of acute pancreatitis in pregnancy (APIP) on pregnancy outcomes and neonates. METHODS: A retrospective analysis was performed for 33 APIP patients and 31 neonates born alive. RESULTS: Of the 33 APIP patients, 26 (79%) developed APIP in the late pregnancy. Fourteen (45%) patients had hyperlipidemic APIP, 13 (42%) had biliary APIP, and 4 (13%) had other types of APIP. According to the severity, 22 (67%) were mild APIP, 5 (15%) were moderate APIP, and 6 were severe APIP...
April 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29658448/-clinical-features-and-prognosis-of-preterm-infants-with-varying-degrees-of-bronchopulmonary-dysplasia
#18
Wen-Li Li, Fa-Lin Xu, Ming Niu, Meng-Di Liu, Hui-Fang Dong
OBJECTIVE: To study the clinical features and prognosis of preterm infants with varying degrees of bronchopulmonary dysplasia (BPD). METHODS: The clinical data of 144 preterm infants with a gestational age of <32 weeks who were admitted to the neonatal intensive care unit from March 2014 to March 2016 and were diagnosed with BPD were collected. According to the severity of BPD, these preterm infants were divided into mild group with 81 infants and moderate/severe group with 63 infants...
April 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29658447/-treatment-and-prognosis-of-pulmonary-hemorrhage-in-preterm-infants-during-2007-2016
#19
Wei-Wei Pan, Xiao-Mei Tong
OBJECTIVE: To study the treatment and prognosis of pulmonary hemorrhage in preterm infants. METHODS: A total of 106 preterm infants diagnosed with pulmonary hemorrhage, who were hospitalized in the neonatal ward of Peking University Third Hospital between 2007 and 2016, were enrolled. These patients were divided into 2007-2011 group (34 cases) and 2012-2016 group (72 cases) according to the time of hospitalization, divided into conventional-frequency ventilation group (43 cases) and high-frequency oscillatory ventilation (HFOV) group (63 cases) according to the respiratory support method used after the development of pulmonary hemorrhage, and divided into non-operation group (34 cases) and operation group (14 cases) according to whether PDA ligation was performed for the unclosed PDA before pulmonary hemorrhage...
April 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29656690/maternal-blood-endotoxin-activity-in-pregnancies-complicated-by-preterm-premature-rupture-of-membranes
#20
Stefania Ronzoni, Rohan D'Souza, Oksana Shynlova, Stephen Lye, Kellie E Murphy
OBJECTIVE: To compare maternal blood endotoxin activity (EA) in women with preterm premature rupture of membranes (PPROM) with gestational age (GA) matched controls; to evaluate serial EA till birth in pPROM and its correlation with latency to delivery. METHODS: We followed singleton preterm pregnancies from admission with PPROM until birth. Uncomplicated, GA-matched pregnancies served as controls. Demographics, birth and neonatal outcomes were collected. EA (EAA™) was assessed serially in PPROM and at study entry in controls...
April 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
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