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https://www.readbyqxmd.com/read/28097428/goal-formulation-and-tracking-in-child-mental-health-settings-when-is-it-more-likely-and-is-it-associated-with-satisfaction-with-care
#1
Jenna Jacob, Davide De Francesco, Jessica Deighton, Duncan Law, Miranda Wolpert, Julian Edbrooke-Childs
Goal formulation and tracking may support preference-based care. Little is known about the likelihood of goal formulation and tracking and associations with care satisfaction. Logistic and Poisson stepwise regressions were performed on clinical data for N = 3757 children from 32 services in the UK (M age = 11; SDage = 3.75; most common clinician-reported presenting problem was emotional problems = 55.6%). Regarding the likelihood of goal formulation, it was more likely for pre-schoolers, those with learning difficulties or those with both hyperactivity disorder and conduct disorder...
January 18, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28097160/contribution-to-the-molecular-systematics-of-the-genus-capoeta-from-the-south-caspian-sea-basin-using-mitochondrial-cytochrome-b-sequences-teleostei-cyprinidae
#2
Halimeh Zareian, Hamid Reza Esmaeili, Adeleh Heidari, Majid Reza Khoshkholgh, Hamed Mousavi-Sabet
Traditionally, Capoeta populations from the southern Caspian Sea basin have been considered as Capoeta capoeta gracilis. Study on the phylogenetic relationship of Capoeta species using mitochondrial cytochrome b gene sequences show that Capoeta population from the southern Caspian Sea basin is distinct species and receive well support (posterior probability of 100%). Based on the tree topologies obtained from Bayesian and Maximum Likelihood methods, three main groups for the studied Capoeta were detected: Clade I) Capoeta trutta group (the Mesopotamian Capoeta group) including closely related taxa (e...
June 2016: Molecular Biology Research Communications
https://www.readbyqxmd.com/read/28097059/the-complete-chloroplast-genome-sequence-of-an-endemic-monotypic-genus-hagenia-rosaceae-structural-comparative-analysis-gene-content-and-microsatellite-detection
#3
Andrew W Gichira, Zhizhong Li, Josphat K Saina, Zhicheng Long, Guangwan Hu, Robert W Gituru, Qingfeng Wang, Jinming Chen
Hagenia is an endangered monotypic genus endemic to the topical mountains of Africa. The only species, Hagenia abyssinica (Bruce) J.F. Gmel, is an important medicinal plant producing bioactive compounds that have been traditionally used by African communities as a remedy for gastrointestinal ailments in both humans and animals. Complete chloroplast genomes have been applied in resolving phylogenetic relationships within plant families. We employed high-throughput sequencing technologies to determine the complete chloroplast genome sequence of H...
2017: PeerJ
https://www.readbyqxmd.com/read/28096345/the-nbs-lrr-architectures-of-plant-r-proteins-and-metazoan-nlrs-evolved-in-independent-events
#4
Jonathan M Urbach, Frederick M Ausubel
There are intriguing parallels between plants and animals, with respect to the structures of their innate immune receptors, that suggest universal principles of innate immunity. The cytosolic nucleotide binding site-leucine rich repeat (NBS-LRR) resistance proteins of plants (R-proteins) and the so-called NOD-like receptors of animals (NLRs) share a domain architecture that includes a STAND (signal transduction ATPases with numerous domains) family NTPase followed by a series of LRRs, suggesting inheritance from a common ancestor with that architecture...
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28095663/morphology-and-molecular-phylogeny-of-raillietina-spp-cestoda-cyclophyllidea-davaineidae-from-domestic-chickens-in-thailand
#5
Preeyaporn Butboonchoo, Chalobol Wongsawad, Amnat Rojanapaibul, Jong-Yil Chai
Raillietina species are prevalent in domestic chickens (Gallus gallus domesticus) in Phayao province, northern Thailand. Their infection may cause disease and death, which affects the public health and economic situation in chicken farms. The identification of Raillietina has been based on morphology and molecular analysis. In this study, morphological observations using light (LM) and scanning electron microscopies (SEM) coupled with molecular analysis of the internal transcribed spacer 2 (ITS2) region and the nicotinamide adenine dinucleotide dehydrogenase subunit 1 (ND1) gene were employed for precise identification and phylogenetic relationship studies of Raillietina spp...
December 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28095416/meta-gwas-accuracy-and-power-metagap-calculator-shows-that-hiding-heritability-is-partially-due-to-imperfect-genetic-correlations-across-studies
#6
Ronald de Vlaming, Aysu Okbay, Cornelius A Rietveld, Magnus Johannesson, Patrik K E Magnusson, André G Uitterlinden, Frank J A van Rooij, Albert Hofman, Patrick J F Groenen, A Roy Thurik, Philipp D Koellinger
Large-scale genome-wide association results are typically obtained from a fixed-effects meta-analysis of GWAS summary statistics from multiple studies spanning different regions and/or time periods. This approach averages the estimated effects of genetic variants across studies. In case genetic effects are heterogeneous across studies, the statistical power of a GWAS and the predictive accuracy of polygenic scores are attenuated, contributing to the so-called 'missing heritability'. Here, we describe the online Meta-GWAS Accuracy and Power (MetaGAP) calculator (available at www...
January 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28095298/molecular-identification-and-genotyping-of-trypanosoma-cruzi-dna-in-autochthonous-chagas-disease-patients-from-texas-usa
#7
Melissa N Garcia, Hadley Burroughs, Rodion Gorchakov, Sarah M Gunter, Eric Dumonteil, Kristy O Murray, Claudia P Herrera
The parasitic protozoan Trypanosoma cruzi, the causative agent of Chagas disease, is widely distributed throughout the Americas, from the southern United States (US) to northern Argentina, and infects at least 6 million people in endemic areas. Much remains unknown about the dynamics of T. cruzi transmission among mammals and triatomine vectors in sylvatic and peridomestic eco-epidemiological cycles, as well as of the risk of transmission to humans in the US. Identification of T. cruzi DTUs among locally-acquired cases is necessary for enhancing our diagnostic and clinical prognostic capacities, as well as to understand parasite transmission cycles...
January 14, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28095201/multisensory-bayesian-inference-depends-on-synapse-maturation-during-training-theoretical-analysis-and-neural-modeling-implementation
#8
Mauro Ursino, Cristiano Cuppini, Elisa Magosso
Recent theoretical and experimental studies suggest that in multisensory conditions, the brain performs a near-optimal Bayesian estimate of external events, giving more weight to the more reliable stimuli. However, the neural mechanisms responsible for this behavior, and its progressive maturation in a multisensory environment, are still insufficiently understood. The aim of this letter is to analyze this problem with a neural network model of audiovisual integration, based on probabilistic population coding-the idea that a population of neurons can encode probability functions to perform Bayesian inference...
January 17, 2017: Neural Computation
https://www.readbyqxmd.com/read/28095191/maximum-pseudolikelihood-estimation-for-model-based-clustering-of-time-series-data
#9
Hien D Nguyen, Geoffrey J McLachlan, Pierre Orban, Pierre Bellec, Andrew L Janke
Mixture of autoregressions (MoAR) models provide a model-based approach to the clustering of time series data. The maximum likelihood (ML) estimation of MoAR models requires evaluating products of large numbers of densities of normal random variables. In practical scenarios, these products converge to zero as the length of the time series increases, and thus the ML estimation of MoAR models becomes infeasible without the use of numerical tricks. We propose a maximum pseudolikelihood (MPL) estimation approach as an alternative to the use of numerical tricks...
January 17, 2017: Neural Computation
https://www.readbyqxmd.com/read/28094282/evidence-of-neofunctionalization-after-the-duplication-of-the-highly-conserved-polycomb-group-gene-caf1-55-in-the-obscura-group-of-drosophila
#10
Juan M Calvo-Martín, Montserrat Papaceit, Carmen Segarra
Drosophila CAF1-55 protein is a subunit of the Polycomb repressive complex PRC2 and other protein complexes. It is a multifunctional and evolutionarily conserved protein that participates in nucleosome assembly and remodelling, as well as in the epigenetic regulation of a large set of target genes. Here, we describe and analyze the duplication of Caf1-55 in the obscura group of Drosophila. Paralogs exhibited a strong asymmetry in evolutionary rates, which suggests that they have evolved according to a neofunctionalization process...
January 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28094083/unmasking-evolutionary-diversity-among-two-closely-related-south-african-legless-skink-species-acontinae-acontias-using-molecular-data
#11
Theo Busschau, Werner Conradie, Adriaan Jordaan, Savel R Daniels
We examined species boundaries among two phylogenetically closely related and morphologically similar South African fossorial legless skink species, Acontias breviceps and Acontias gracilicauda. Samples of these two species were collected throughout their distribution ranges and sequenced for three DNA loci (two mitochondrial loci, 16S rRNA and cytochrome b (Cyt b), plus the nuclear locus prolactin). Phylogenetic relationships were determined using maximum parsimony, Bayesian inference and maximum likelihood analyses of the combined DNA sequence data set...
December 10, 2016: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/28092637/non-invasive-classification-of-breast-microcalcifications-using-x-ray-coherent-scatter-computed-tomography
#12
Bahaa Ghammraoui, Lucretiu M Popescu
We investigate the use of energy dispersive x-ray coherent scatter computed tomography (ED-CSCT) as a non-invasive diagnostic method to differentiate between type I and type II breast calcifications. This approach is sensitive to the differences of composition and internal crystal structure of different types of microcalcifications. The study is carried out by simulating a CSCT system with a scanning pencil beam, considering a polychromatic x-ray source and an energy-resolving photon counting detector. In a first step, the multidimensional angle and energy distributed CSCT data is reduced to the projection-space distributions of only a few components, corresponding to the expected target composition: adipose, glandular tissue, weddellite (calcium oxalate) for type I calcifications, and hydroxyapatite for type II calcifications...
February 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28092526/estimation-of-basis-line-integrals-in-a-spectral-distortion-modeled-photon-counting-detector-using-low-order-polynomial-approximation-of-x-ray-transmittance
#13
Okkyun Lee, Steffen Kappler, Christoph Polster, Katsuyuki Taguchi
Photon counting detector (PCD)-based computed tomography exploits spectral information from a transmitted x-ray spectrum to estimate basis line-integrals. The recorded spectrum, however, is distorted and deviates from the transmitted spectrum due to spectral response effect (SRE). Therefore, the SRE needs to be compensated for when estimating basis lineintegrals. One approach is to incorporate the SRE model with an incident spectrum into the PCD measurement model and the other approach is to perform a calibration process that inherently includes both the SRE and the incident spectrum...
October 26, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28091959/genetic-variation-in-mitochondrial-genes-of-the-tick-haemaphysalis-flava-collected-from-wild-hedgehogs-in-china
#14
Zhong-Bo Li, Tian-Yin Cheng, Xing-Li Xu, Lu-Lin Song, Guo-Hua Liu
The tick Haemaphysalis flava (Acari: Ixodidae) is an important ectoparasite, which causes direct damage to their hosts and also acts as a vector of various infectious disease agents in China. Despite its significance, the epidemiology, genetics and biology of H. flava has not been studied in detail. In the present study, the genetic variation in three mitochondrial (mt) DNA regions, namely cytochrome c oxidase subunit 1 (cox1) and NADH dehydrogenase subunit 1 and 4 (nad1 and nad4), was examined in H. flava ticks collected from wild hedgehogs in China...
January 16, 2017: Experimental & Applied Acarology
https://www.readbyqxmd.com/read/28089813/parasciadicleithrum-octofasciatum-n-gen-n-sp-monogenoidea-dactylogyridae-parasite-of-rocio-octofasciata-regan-cichlidae-perciformes-from-mexico-characterised-by-morphological-and-molecular-evidence
#15
Carlos A Mendoza-Palmero, Isabel Blasco-Costa, David Hernández-Mena, Gerardo Pérez-Ponce de León
Based on an integrative taxonomic approach, combining morphological characters and partial sequences of the 28S rRNA gene, a new genus and species, Parasciadicleithrum octofasciatum, is proposed to accommodate dactylogyrids infecting the gills of Rocio octofasciata (Cichlidae) from a tributary of the Lacantún River basin, Chiapas State, southern Mexico. Morphologically, the new genus resembles members of Sciadicleithrum (Dactylogyridae) in the presence of membranes on the anterior margins of both ventral and dorsal haptoral bars...
January 13, 2017: Parasitology International
https://www.readbyqxmd.com/read/28088402/historical-relationships-of-three-enigmatic-phasianid-genera-aves-galliformes-inferred-using-phylogenomic-and-mitogenomic-data
#16
Ning Wang, Peter A Hosner, Bin Liang, Edward L Braun, Rebecca T Kimball
The phylogeny of the Phasianidae (pheasants, partridges, and allies) has been studied extensively. However, these studies have largely ignored three enigmatic genera because of scarce DNA source material and limited overlapping phylogenetic data: blood pheasants (Ithaginis), snow partridges (Lerwa), and long-billed partridges (Rhizothera). Thus, phylogenetic positions of these three genera remain uncertain in what is otherwise a well-resolved phylogeny. Previous studies using different data types place Lerwa and Ithaginis in similar positions, but the absence of overlapping data means the relationship between them could not be inferred...
January 11, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28088189/mars-improving-multiple-circular-sequence-alignment-using-refined-sequences
#17
Lorraine A K Ayad, Solon P Pissis
BACKGROUND: A fundamental assumption of all widely-used multiple sequence alignment techniques is that the left- and right-most positions of the input sequences are relevant to the alignment. However, the position where a sequence starts or ends can be totally arbitrary due to a number of reasons: arbitrariness in the linearisation (sequencing) of a circular molecular structure; or inconsistencies introduced into sequence databases due to different linearisation standards. These scenarios are relevant, for instance, in the process of multiple sequence alignment of mitochondrial DNA, viroid, viral or other genomes, which have a circular molecular structure...
January 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28087420/on-the-quirks-of-maximum-parsimony-and-likelihood-on-phylogenetic-networks
#18
Christopher Bryant, Mareike Fischer, Simone Linz, Charles Semple
Maximum parsimony is one of the most frequently-discussed tree reconstruction methods in phylogenetic estimation. However, in recent years it has become more and more apparent that phylogenetic trees are often not sufficient to describe evolution accurately. For instance, processes like hybridization or lateral gene transfer that are commonplace in many groups of organisms and result in mosaic patterns of relationships cannot be represented by a single phylogenetic tree. This is why phylogenetic networks, which can display such events, are becoming of more and more interest in phylogenetic research...
January 10, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28081011/spectrum-reconstruction-method-based-on-the-detector-response-model-calibrated-by-x-ray-fluorescence
#19
Ruizhe Li, Liang Li, Zhiqiang Chen
Accurate estimation of distortion-free spectra is important but difficult in various applications, especially for spectral computed tomography. Two key problems must be solved to reconstruct the incident spectrum. One is the acquisition of the detector energy response. It can be calculated by Monte Carlo simulation, which requires detailed modeling of the detector system and a high computational power. It can also be acquired by establishing a parametric response model and be calibrated using monochromatic x-ray sources, such as synchrotron sources or radioactive isotopes...
February 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28077778/uncertain-tree-discriminating-among-competing-approaches-to-the-phylogenetic-analysis-of-phenotype-data
#20
Mark N Puttick, Joseph E O'Reilly, Alastair R Tanner, James F Fleming, James Clark, Lucy Holloway, Jesus Lozano-Fernandez, Luke A Parry, James E Tarver, Davide Pisani, Philip C J Donoghue
Morphological data provide the only means of classifying the majority of life's history, but the choice between competing phylogenetic methods for the analysis of morphology is unclear. Traditionally, parsimony methods have been favoured but recent studies have shown that these approaches are less accurate than the Bayesian implementation of the Mk model. Here we expand on these findings in several ways: we assess the impact of tree shape and maximum-likelihood estimation using the Mk model, as well as analysing data composed of both binary and multistate characters...
January 11, 2017: Proceedings. Biological Sciences
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