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https://www.readbyqxmd.com/read/28222520/interactive-effects-of-dementia-severity-and-comorbidities-on-medicare-expenditures
#1
Carolyn W Zhu, Stephanie Cosentino, Katherine A Ornstein, Yian Gu, Howard Andrews, Yaakov Stern
BACKGROUND: Few studies have examined how dementia and comorbidities may interact to affect healthcare expenditures. OBJECTIVE: To examine whether effects of dementia severity on Medicare expenditures differed for individuals with different levels of comorbidities. METHODS: Data are drawn from the Washington Heights-Inwood Columbia Aging Project (WHICAP). Comprehensive clinical assessments of dementia severity were systematically carried out at ∼18 month intervals...
February 10, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28222514/one-year-evolution-of-behavioral-and%C3%A2-psychological-symptoms-of-dementia-in-patients-initially-hospitalized-in%C3%A2-cognitive-behavioral-units-the-evital-prospective-cohort
#2
Isabelle Rouch, Elodie Pongan, Béatrice Trombert, Florence Fabre, Nicolas Auguste, Claire Sellier, Magalie Freulon, Sophie Jacqueline, Denis Federico, Christelle Mouchoux, Géraldine Martin-Gaujard, Pierre Krolak-Salmon, Bernard Laurent, Jean-Michel Dorey
BACKGROUND: The 2008-2012 French Alzheimer's Plan has provided hospital Cognitive and Behavioral Units (CBU) to improve the management of patients with productive behavioral and psychological symptoms of dementia (BPSD). Little is known concerning the behavioral outcome of these patients after discharge. OBJECTIVE: The present study investigated the long-term evolution of BPSD over one year after CBU discharge. METHODS: The EVITAL cohort included 221 participants admitted to the CBUs of 3 French hospitals...
February 10, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28222490/the-prevalence-of-convergence-insufficiency-in-iran-a-population-based-study
#3
Hassan Hashemi, Payam Nabovati, Mehdi Khabazkhoob, Hadi Ostadimoghaddam, Asgar Doostdar, Ehsan Shiralivand, Abbasali Yekta
PURPOSE: The aim was to determine the prevalence of convergence insufficiency and its relationship with age, gender and refractive error in a population-based study. METHODS: In this cross-sectional study, all residents over one year old in Mashhad city, in the north east of Iran, were sampled through random stratified cluster sampling. After selecting samples and their participation in the study, they all had eye examinations including the measurement of visual acuity, refraction, binocular vision assessment, including cover test, measurement of near point of convergence and fusional vergences and finally, slitlamp biomicroscopy...
February 21, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28222488/explaining-counterfeit-alcohol-purchases-in-russia
#4
Zoya Kotelnikova
BACKGROUND: Alcohol is a common target of counterfeiting in Russia. Counterfeit alcohol is defined here as the manufacture, distribution, unauthorized placement (forgery) of protected commodity trademarks, and infringement of the exclusive rights of the registered trademark holders of alcoholic beverages. It is often argued that the expansion of the counterfeit product market is due to the steady demand of economically disadvantaged people for low-priced goods. The situation becomes more complicated once deceptive and nondeceptive forms of counterfeiting are taken into account...
February 21, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28222391/a-clinically-applicable-non-invasive-method-to-quantitatively-assess-the-visco-hyperelastic-properties-of-human-heel-pad-implications-for-assessing-the-risk-of-mechanical-trauma
#5
Sara Behforootan, Panagiotis E Chatzistergos, Nachiappan Chockalingam, Roozbeh Naemi
INTRODUCTION: Pathological conditions such as diabetic foot and plantar heel pain are associated with changes in the mechanical properties of plantar soft tissue. However, the causes and implications of these changes are not yet fully understood. This is mainly because accurate assessment of the mechanical properties of plantar soft tissue in the clinic remains extremely challenging. PURPOSE: To develop a clinically viable non-invasive method of assessing the mechanical properties of the heel pad...
February 9, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28222217/multi-component-diffusion-characterization-of-radiation-induced-white-matter-damage
#6
Roshan A Karunamuni, Nathan S White, Carrie R McDonald, Michael Connor, Niclas Pettersson, Tyler M Seibert, Joshua Kuperman, Nikdokht Farid, Vitali Moiseenko, Anders M Dale, Jona A Hattangadi-Gluth
PURPOSE: We used multi-b-value diffusion models to characterize microstructural white matter changes after brain radiation into fast and slow components, in order to better understand the pathophysiology of radiation-induced tissue damage. METHODS: Fourteen patients were included in this retrospective analysis with imaging prior to, and at 1, 4-5, and 9-10 months after radiotherapy (RT). Diffusion signal decay within brain white matter was fit to a bi-exponential model to separate changes within the slow and fast components...
February 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/28222155/glm-based-optimization-of-ngs-data-analysis-a-case-study-of-roche-454-ion-torrent-pgm-and-illumina-nextseq-sequencing-data
#7
Sarah Sandmann, Aniek O de Graaf, Bert A van der Reijden, Joop H Jansen, Martin Dugas
BACKGROUND: There are various next-generation sequencing techniques, all of them striving to replace Sanger sequencing as the gold standard. However, false positive calls of single nucleotide variants and especially indels are a widely known problem of basically all sequencing platforms. METHODS: We considered three common next-generation sequencers-Roche 454, Ion Torrent PGM and Illumina NextSeq-and applied standard as well as optimized variant calling pipelines...
2017: PloS One
https://www.readbyqxmd.com/read/28222145/cataract-surgery-causes-biomechanical-alterations-to-the-eye-detectable-by-corvis-st-tonometry
#8
Yoshitake Kato, Shunsuke Nakakura, Ryo Asaoka, Kanae Matsuya, Yuki Fujio, Yoshiaki Kiuchi
PURPOSE: Modern cataract surgery is generally considered to bring about modest and sustained intraocular pressure (IOP) reduction. However, the pathophysiological mechanism for this remains unclear. Moreover, a change in ocular biomechanical properties after surgery can affect the measurement of IOP. The aim of the study is to investigate ocular biomechanics, before and following cataract surgery, using Corvis ST tonometry (CST). PATIENTS AND METHODS: Fifty-nine eyes of 59 patients with cataract were analyzed...
2017: PloS One
https://www.readbyqxmd.com/read/28222101/costs-and-effects-of-a-state-wide-health-promotion-program-in-primary-schools-in-germany-the-baden-w%C3%A3-rttemberg-study-a-cluster-randomized-controlled-trial
#9
Dorothea Kesztyüs, Romy Lauer, Tibor Kesztyüs, Reinhold Kilian, Jürgen M Steinacker
AIM: To evaluate the cost-effectiveness of the state-wide implementation of the health promotion program "Join the Healthy Boat" in primary schools in Germany. METHODS: Cluster-randomized intervention trial with wait-list control group. Anthropometric data of 1733 participating children (7.1 ± 0.6 years) were taken by trained staff before and after a one year intervention period in the academic year 2010/11. Parents provided information about the health status, and the health behaviour of their children and themselves, parental anthropometrics, and socio-economic background variables...
2017: PloS One
https://www.readbyqxmd.com/read/28222047/coherent-control-of-optical-absorption-and-the-energy-transfer-pathway-of-an-infrared-quantum-dot-hybridized-with-a-vo2-nanoparticle
#10
Ali Hatef, Naser Zamani, William Johnston
We systematically investigate the optical response of a semiconductor quantum dot (QD) hybridized with a vanadium dioxide nanoparticle (VO2NP) in the infrared (IR) region. The VO2NP features a semiconductor to metal phase change characteristic below and above a critical temperature that leads to an abrupt change in the particle's optical properties. This feature means that the QD-VO2NP hybrid system can support the coherent coupling of exciton-polaritons and exciton-plasmon polaritons in the semiconductor and metal phases of the VO2NP, respectively...
February 21, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28221998/reduction-of-assessment-time-for-stroke-related-impairments-using-robotic-evaluation
#11
Sayyed Mostafa Mostafavi, Stephen H Scott, Sean P Dukelow, Parvin Mousavi
Robotic technologies can provide objective, reliable tools for assessing a broad range of sensory, motor and cognitive functions. However, as additional tasks are developed on these platforms, the time necessary to assess a patient increases. In this paper, we present a hierarchical task selection strategy for five tasks that form part of the battery of standard tests performed on the KINARM robotic system. The strategy is built using dependencies derived through three types of analyses: i) nonlinear hierarchical ordering theory is applied to determine the ordering of five tasks; ii) the parameters of all tasks are also ranked using non-linear hierarchical ordering theory; and iii) a modeling technique, fast orthogonal search (FOS), is applied to assess the predictive power of each robotic task for estimation of other task parameters...
February 16, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28221962/modeling-the-effect-of-temperature-and-water-activity-on-the-thermal-resistance-of-salmonella-enteritidis-pt-30-in-wheat-flour
#12
Danielle F Smith, Ian M Hildebrandt, Kaitlyn E Casulli, Kirk D Dolan, Bradley P Marks
Salmonella continues to be a problem associated with low-moisture foods, particularly given enhanced thermal resistance at lower water activity (aw). However, there is a scarcity of thermal inactivation models accounting for the effect of aw. The objective of this study was to test multiple secondary models for the effect of product (wheat flour) aw on Salmonella enterica Enteritidis phage type 30 thermal resistance. A full-factorial experimental design included three temperatures (75, 80, and 85°C) and four aw values (~0...
December 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221960/mycotoxin-contamination-in-stored-maize-and-groundnuts-based-on-storage-practices-and-conditions-in-subhumid-tropical-africa-the-case-of-kilosa-district-tanzania
#13
K S Magembe, M W Mwatawala, D P Mamiro
Experiments were conducted to assess the influence of storage practices on mycotoxin incidences in stored maize and groundnuts in Kilosa District, Eastern Central Tanzania. Factorial experiments were used to test the effects of processing, storage conditions, and protectants at 3-month intervals for 12 weeks. Temperature and relative humidity data were recorded by using data loggers. The differences among the treatment means were compared using Tukey's honestly significant difference test at 5% probability level...
December 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221958/using-a-six-sigma-fishbone-analysis-approach-to-evaluate-the-effect-of-extreme-weather-events-on-salmonella-positives-in-young-chicken-slaughter-establishments
#14
John W Linville, Douglas Schumann, Christopher Aston, Stephanie Defibaugh-Chavez, Scott Seebohm, Lucy Touhey
A six sigma fishbone analysis approach was used to develop a machine learning model in SAS, Version 9.4, by using stepwise linear regression. The model evaluated the effect of a wide variety of variables, including slaughter establishment operational measures, normal (30-year average) weather, and extreme weather events on the rate of Salmonella -positive carcasses in young chicken slaughter establishments. Food Safety and Inspection Service (FSIS) verification carcass sampling data, as well as corresponding data from the National Oceanographic and Atmospheric Administration and the Federal Emergency Management Agency, from September 2011 through April 2015, were included in the model...
December 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221892/effects-of-ohmic-heating-including-electric-field-intensity-and-frequency-on-thermal-inactivation-of-bacillus-subtilis-spores
#15
Suguru Murashita, Shuso Kawamura, Shigenobu Koseki
Methods for microbial inactivation are important in the food industry; however, conventional external heating (CH) reduces food quality. Accordingly, the nonthermal effects of ohmic heating (OH) on Bacillus subtilis spores in a sodium chloride aqueous solution at 101°C (i.e., the boiling point), as well as the effects of electric field intensity and frequency during OH, were investigated. Survival kinetics were compared between OH and external CH. The inactivation effect on B. subtilis was greater for all electric field conditions (5, 10, and 20 V/cm) than for CH...
January 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28221887/soil-type-soil-moisture-and-field-slope-influence-the-horizontal-movement-of-salmonella-enterica-and-citrobacter-freundii-from-floodwater-through-soil
#16
Mary Theresa Callahan, Shirley A Micallef, Robert L Buchanan
Pathogens in soil are readily mobilized by infiltrating water to travel downward through the soil. However, limited data are available on the horizontal movement of pathogens across a field. This study used a model system to evaluate the influence of soil type, initial soil moisture content, and field slope on the movement of Salmonella enterica serovar Newport across a horizontal plane of soil under flooding conditions. Three soil types of varying clay content were moistened to 40, 60, or 80% of their maximum water-holding capacities and flooded with water containing 6 log CFU/ml Salmonella Newport and Citrobacter freundii , the latter being evaluated as a potential surrogate for S...
January 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28221882/microbial-performance-of-food-safety-control-and-assurance-activities-in-a-fresh-produce-processing-sector-measured-using-a-microbial-assessment-scheme-and-statistical-modeling
#17
Patrick Murigu Kamau Njage, Chemutai Tonui Sawe, Cecilia Moraa Onyango, I Habib, Edmund Njeru Njagi, Marc Aerts, Geert Molenberghs
Current approaches such as inspections, audits, and end product testing cannot detect the distribution and dynamics of microbial contamination. Despite the implementation of current food safety management systems, foodborne outbreaks linked to fresh produce continue to be reported. A microbial assessment scheme and statistical modeling were used to systematically assess the microbial performance of core control and assurance activities in five Kenyan fresh produce processing and export companies. Generalized linear mixed models and correlated random-effects joint models for multivariate clustered data followed by empirical Bayes estimates enabled the analysis of the probability of contamination across critical sampling locations (CSLs) and factories as a random effect...
January 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28221878/prediction-of-escherichia-coli-o157-h7-salmonella-and-listeria-monocytogenes-growth-in-leafy-greens-without-temperature-control
#18
Abhinav Mishra, Miao Guo, Robert L Buchanan, Donald W Schaffner, Abani K Pradhan
A recent study by the Centers for Disease Control and Prevention reported that between 1998 and 2008, leafy greens outbreaks accounted for 22.3% of foodborne outbreaks in the United States. Several studies on the growth of bacteria at different temperatures have been conducted; however, there is a need for the prediction of bacterial growth when leafy greens are transported without temperature control. Food products, when taken out of refrigeration, undergo a temperature change, with the rate of temperature change being proportional to the difference in the temperature of food and its surroundings...
January 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28221715/hybrid-nanoparticle-pyramids-for-intracellular-dual-micrornas-biosensing-and-bioimaging
#19
Si Li, Liguang Xu, Maozhong Sun, Xiaoling Wu, Liqiang Liu, Hua Kuang, Chuanlai Xu
This study strategically fabricates multifunctional nanopyramids to allow the ultrasensitive quantification of dual microRNAs (miR-203(b) and miR-21) in living cells and their responsive bioimaging in vivo. The nanopyramids, composed of Au-Cu9 S5 nanoparticles (NPs), upconversion NPs (UCNPs), and Ag2 S NPs, emit two luminescent signals simultaneously with excitation at 808 nm, arising from the UCNPs at 541 nm in the visible region and from the Ag2 S NPs at 1227 nm in the second window of near-infrared (NIR-II) region...
February 21, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28221244/hla-amino-acid-polymorphisms-and-kidney-allograft-survival
#20
Malek Kamoun, Keith P McCullough, Martin Maiers, Marcelo A Fernandez Vina, Hongzhe Li, Valerie Teal, Alan B Leichtman, Robert M Merion
BACKGROUND: The association of HLA mismatching with kidney allograft survival has been well established. We examined whether amino acid mismatches at the antigen recognition site of HLA molecules represent independent and incremental risk factors for kidney graft failure (GF) beyond those mismatches assessed at the antigenic (2-digit) specificity. METHODS: Data on 240,024 kidney transplants performed between 1987 and 2009 were obtained from the Scientific Registry of Transplant Recipients...
February 18, 2017: Transplantation
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