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https://www.readbyqxmd.com/read/29238216/improved-health-related-quality-of-life-participation-and-autonomy-in-patients-with-treatment-resistant-chronic-pain-after-an-intensive-social-cognitive-intervention-with-the-participation-of-support-partners
#1
Peter Joseph Jongen, Rob P Ruimschotel, Y M Museler-Kreijns, Tmc Dragstra, L Duyverman, J Valkenburg-Vissers, J Cornelissen, R Lagrand, Rogier Donders, A Hartog
Despite the availability of various specific treatments, most patients with chronic pain (CP) consider their pain problem as undertreated. Recently, multiple sclerosis (MS) patients who were given an intensive 3-day social cognitive treatment with the participation of support partners experienced lasting improvements in health-related quality of life (HRQoL) and self-efficacy. In this study, a similar intervention was given to treatment-resistant CP patients with stressors, relational problems with support partner, and distress, anxiety or depression...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29231914/determinants-of-late-life-depression-in-residents-of-long-term-care-facility
#2
Urszula Horwath, Katarzyna Szczerbińska
Mental disorders, such as dementia and depression, are beside chronic somatic diseases, the most common problem in residents of longterm care facilities (LTCF). Late-life depression refers to depressive symptoms that arise in adults older than 65 years. According to literature review, older people tend to differ from middle-aged adults in presentation of depression. AIM: Mental disorders, such as dementia and depression, are beside chronic somatic diseases, the most common problem in residents of longterm care facilities (LTCF)...
November 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29218213/two-cases-of-somatic-type-malignancy-as-a-very-late-relapse-of-testicular-cancer-successfully-managed-by-surgical-resection
#3
Satoshi Washino, Tsuzumi Konishi, Kimitoshi Saito, Masashi Ohshima, Yuhki Nakamura, Tomoaki Miyagawa
A late-relapse germ cell tumor might contain malignant non-germ cell tumors, known as 'somatic-type malignancy (SM)'. The development of a secondary SM is rare, and this phenomenon remains poorly understood. Case 1 developed lung metastasis 13 years after chemotherapy followed by retroperitoneal lymph node dissection for stage IIA non-seminoma. The tumor increased in size after chemotherapy. The patient underwent a pneumonectomy. Pathology revealed an adenocarcinoma with immature teratoma. The patient has experienced no relapse for 9 years...
November 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29216870/prevalence-and-severity-of-menopause-symptoms-among-perimenopausal-and-postmenopausal-women-aged-30-49%C3%A2-years-in-gulele-sub-city-of-addis-ababa-ethiopia
#4
Engida Yisma, Natnael Eshetu, Stephanie Ly, Berhanu Dessalegn
BACKGROUND: Menopause is a natural phenomenon occurring as women approach middle-age. It is characterized by declining of ovarian function and onset of the last menstrual period and subsequent 12-month cessation of menstruation. Due to a growing aging population and longer life expectancies, sub-Saharan African women will spend a significant portion of their lives in postmenopause. Menopausal symptom research has been primarily conducted on Caucasian women from high-income countries. Understanding menopause symptom prevalence and perceptions among diverse women in Ethiopia will better inform reproductive health care...
December 8, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29204343/episodic-memory-after-trauma-exposure-medial-temporal-lobe-function-is-positively-related-to-re-experiencing-and-inversely-related-to-negative-affect-symptoms
#5
Jennifer S Stevens, Renuka Reddy, Ye Ji Kim, Sanne J H van Rooij, Timothy D Ely, Stephan Hamann, Kerry J Ressler, Tanja Jovanovic
Hippocampal structure is particularly sensitive to trauma and other stressors. However, previous findings linking hippocampal function with trauma-related psychopathology have been mixed. Heterogeneity in psychological responses to trauma has not been considered with respect to hippocampal function and may contribute to mixed findings. To address these issues, we examined associations between data-driven symptom dimensions and episodic memory formation, a key function of the hippocampus, in a trauma-exposed sample...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29197180/acupuncture-for-neuropathic-pain-in-adults
#6
REVIEW
Zi Yong Ju, Ke Wang, Hua Shun Cui, Yibo Yao, Shi Min Liu, Jia Zhou, Tong Yu Chen, Jun Xia
BACKGROUND: Neuropathic pain may be caused by nerve damage, and is often followed by changes to the central nervous system. Uncertainty remains regarding the effectiveness and safety of acupuncture treatments for neuropathic pain, despite a number of clinical trials being undertaken. OBJECTIVES: To assess the analgesic efficacy and adverse events of acupuncture treatments for chronic neuropathic pain in adults. SEARCH METHODS: We searched CENTRAL, MEDLINE, Embase, four Chinese databases, ClinicalTrials...
December 2, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29172593/internet-based-cognitive-behavioral-therapy-versus-psychoeducation-control-for-illness-anxiety-disorder-and-somatic-symptom-disorder-a-randomized-controlled-trial
#7
Jill M Newby, Jessica Smith, Shivani Uppal, Elizabeth Mason, Alison E J Mahoney, Gavin Andrews
OBJECTIVE: To examine the efficacy of an Internet-delivered cognitive-behavioral therapy (iCBT) program for health anxiety compared to an active psychoeducation control group. METHOD: Individuals (N = 86, mean age: 30 years, 87% female) with a Diagnostic and Statistical Manual of Mental Disorders (5th ed.) diagnosis of illness anxiety disorder or somatic symptom disorder with health anxiety were randomized to either a 6-lesson clinician-guided iCBT program for health anxiety (n = 45) or an active control group who received anxiety psychoeducation, clinical support, and monitoring (control, n = 41) over a 12-week period...
November 27, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29172228/adverse-life-events-increase-risk-for-postpartum-psychiatric-episodes-a-population-based-epidemiologic-study
#8
S Meltzer-Brody, J T Larsen, L Petersen, J Guintivano, A Di Florio, W C Miller, P F Sullivan, T Munk-Olsen
BACKGROUND: Trauma histories may increase risk of perinatal psychiatric episodes. We designed an epidemiological population-based cohort study to explore if adverse childhood experiences (ACE) in girls increases risk of later postpartum psychiatric episodes. METHODS: Using Danish registers, we identified women born in Denmark between January 1980 and December 1998 (129,439 childbirths). Exposure variables were ACE between ages 0 and 15 including: (1) family disruption, (2) parental somatic illness, (3) parental labor market exclusion, (4) parental criminality, (5) parental death, (6) placement in out-of-home care, (7) parental psychopathology excluding substance use, and (8) parental substance use disorder...
November 24, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/29167791/is-delirium-the-cognitive-harbinger-of-frailty-in-older-adults-a-review-about-the-existing-evidence
#9
REVIEW
Giuseppe Bellelli, Rosamaria Moresco, Paola Panina-Bordignon, Beatrice Arosio, Cecilia Gelfi, Alessandro Morandi, Matteo Cesari
Frailty is a clinical syndrome defined by the age-related depletion of the individual's homeostatic reserves, determining an increased susceptibility to stressors and disproportionate exposure to negative health changes. The physiological systems that are involved in the determination of frailty are mutually interrelated, so that when decline starts in a given system, implications may also regard the other systems. Indeed, it has been shown that the number of abnormal systems is more predictive of frailty than those of the abnormalities in any particular system...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29162654/the-impact-of-hereditary-cancer-gene-panels-on-clinical-care-and-lessons-learned
#10
Volkan Okur, Wendy K Chung
Mutations in hereditary cancer syndromes account for a modest fraction of all cancers; however, identifying patients with these germline mutations offers tremendous health benefits to both patients and their family members. There are about 60 genes that confer a high lifetime risk of specific cancers, and this information can be used to tailor prevention, surveillance, and treatment. With advances in next-generation sequencing technologies and the elimination of gene patents for evaluating genetic information, we are now able to analyze multiple genes simultaneously, leading to the widespread clinical use of gene panels for germline cancer testing...
November 2017: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/29162089/patient-perspectives-on-continuity-of-care-adaption-and-preliminary-psychometric-assessment-of-a-norwegian-version-of-the-nijmegen-continuity-questionnaire-ncq-n
#11
Øystein Hetlevik, Merethe Hustoft, Annemarie Uijen, Jörg Aßmus, Sturla Gjesdal
BACKGROUND: Continuity of care is regarded as a core quality element in healthcare. Continuity can be related to one or more specific caregivers but also applies to collaboration within a team or across boundaries of healthcare. Measuring continuity is important to identify problems and evaluate quality improvement of interventions. This study aimed to assess the feasibility and psychometric properties of a Norwegian version of the Nijmegen Continuity Questionnaire (NCQ). METHODS: The NCQ was developed in The Netherlands...
November 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29157298/impressive-response-to-immunotherapy-in-a-metastatic-gastric-cancer-patient-could-somatic-copy-number-alterations-help-patient-selection
#12
Gustavo Dos Santos Fernandes, Daniel da Motta Girardi, Luiza Dib Batista Bugiato Faria, João Paulo Giacomini Bernardes, Renata de Almeida Coudry
BACKGROUND: Metastatic gastric cancer (GC) is an incurable and aggressive disease with a poor prognosis. Immunotherapy is an attractive approach for treating patients with cancer, and studies using immunotherapy have shown promising results in melanoma, kidney and non-small cell lung cancers, among others. CASE PRESENTATION: We present a case of a 50-year-old woman with metastatic GC whose cancer had progressed after first-line chemotherapy and who received pembrolizumab as an experimental treatment...
November 21, 2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/29154604/traditional-and-cyber-victimization-among-adolescents-with-and-without-chronic-pain
#13
Jessica L Fales, Sean Rice, Rachel V Aaron, Tonya M Palermo
OBJECTIVE: Prior research has revealed a link between peer victimization and somatic complaints in healthy youth; however, the peer victimization experiences of youth with clinically significant chronic pain have not been examined. This study aims to determine rates of peer victimization among youth seeking treatment for chronic pain and to compare these rates to a community control group. Relationships between peer victimization, depressive symptoms, and functional disability are also examined...
November 20, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29141732/education-as-an-intervention-toward-recognizing-and-eliminating-incivility
#14
Laura M Schwarz, Nancyruth Leibold
Incivility in nursing is a pervasive and evasive problem that many nurses do not easily recognize or may simply shrug off as "normal." However, incivility produces a hostile work environment and can jeopardize safety. A study was conducted to (a) determine nurses' ability to recognize incivility in nursing after an online educational intervention on incivility, (b) ascertain the effectiveness of online education toward assisting nurses with understanding how to ward off this behavior, and (c) determine the types and effects of incivility participants experienced...
November 1, 2017: Creative Nursing
https://www.readbyqxmd.com/read/29117210/quality-of-life-and-impact-of-pain-in-women-treated-with-aromatase-inhibitors-for-breast-cancer-a-multicenter-cohort-study
#15
MULTICENTER STUDY
Françoise Laroche, Serge Perrot, Terkia Medkour, Paul-Henri Cottu, Jean-Yves Pierga, Jean-Pierre Lotz, Karine Beerblock, Christophe Tournigand, Laure Chauvenet, Didier Bouhassira, Joël Coste
Women with hormone-dependent breast cancer are treated with aromatase inhibitors (AI) to slow disease progression by decreasing estrogen levels. However, AI have adverse effects, including pain, with potentially serious impact on quality of life (QOL) and treatment compliance. We evaluated quality of life during the first year of AI treatment, focusing particularly on the impact of pain. In a multicenter cohort study of 135 women with early-stage breast cancer, free of pain at the initiation of AI treatment, quality of life (by the EORTC QLQ-BR23), somatic and psychic symptoms, psychological characters, temperament and coping strategies were assessed at baseline and at each follow-up visit (1, 3, 6 and 12 months)...
2017: PloS One
https://www.readbyqxmd.com/read/29098971/-the-prognosis-of-medically-unexplained-symptoms
#16
D J C Hanssen, H Knoop, J G M Rosmalen
- The condition where someone has physical symptoms for a number of weeks for which no clear somatic cause can be found, is known as medically unexplained symptoms (MUS).- In this article we give an overview of current insights into the prognosis of MUS.- Extensive somatic testing in patients diagnosed with MUS by a physician, rarely results in a somatic diagnosis.- In approximately half of these patients, MUS disappear spontaneously within one year.- Symptom-related characteristics - such as experiencing multiple physical symptoms simultaneously-, and psychological characteristics - such as unhelpful thoughts - are predictors of an unfavourable prognosis for MUS...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29095126/experiencing-menopause-in-the-uk-the-interrelated-narratives-of-normality-distress-and-transformation
#17
Isabel de Salis, Amanda Owen-Smith, Jenny L Donovan, Debbie A Lawlor
We investigated the experience and perspectives of menopause among 48 UK mothers through qualitative in-depth interviews. Interviews were analyzed thematically then explored using social science theories. Three interdependent narratives emerged: menopause as a normal, biological process, distinct from self and social transitions; menopause as struggle, an "idiom of distress" expressing upset, identity loss, shame, and social upheaval; and menopause as transformative and liberating, arising from biopsychic and relational changes...
November 2, 2017: Journal of Women & Aging
https://www.readbyqxmd.com/read/29089443/detailed-dendritic-excitatory-inhibitory-balance-through-heterosynaptic-spike-timing-dependent-plasticity
#18
Naoki Hiratani, Tomoki Fukai
The balance between excitatory and inhibitory inputs is a key feature of cortical dynamics. Such a balance is arguably preserved in dendritic branches, yet its underlying mechanism and functional roles remain unknown. In this study, we developed computational models of heterosynaptic spike-timing-dependent plasticity (STDP) to show that the excitatory/inhibitory balance in dendritic branches is robustly achieved through heterosynaptic interactions between excitatory and inhibitory synapses. The model reproduces key features of experimental heterosynaptic STDP well, and provides analytical insights...
October 31, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29079542/aapt-diagnostic-criteria-for-chronic-abdominal-pelvic-and-urogenital-pain-irritable-bowel-syndrome
#19
QiQi Zhou, Ursula Wesselmann, Lynn Walker, Linda Lee, Lonnie Zeltzer, G Nicholas Verne
In conjuction with the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) public-private partnership with the US Food and Drug Administration and the American Pain Society (APS), the ACTTION-APS Pain Taxonomy (AAPT) initiative strove to develop the characteristics of a diagnostic system useful for clinical and research purposes across disciplines and types of chronic pain conditions. Following the establishment of these characteristics, a working group of clinicians and clinical and basic scientists with expertise in abdominal, pelvic, and urogenital pain began generating core diagnostic criteria and defining the related extraintestinal somatic pain and other symptoms experienced by patients...
October 24, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29078774/the-kessler-psychological-distress-scale-translation-and-validation-of-an-arabic-version
#20
Scott D Easton, Najwa S Safadi, Yihan Wang, Robert G Hasson
BACKGROUND: The Kessler Psychological Distress Scale has been widely used in assessing psychological distress among general and clinical populations from different cultural backgrounds. To our knowledge, however, researchers have not yet validated any translated versions in Arabic. The purpose of this study was to test the reliability and validity of Arabic translations of the ten item (K10) and six item (K6) versions among public sector employees in the Occupied Palestinian Territories...
October 27, 2017: Health and Quality of Life Outcomes
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