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Biologic mesh

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https://www.readbyqxmd.com/read/28318504/-economic-evaluation-of-medical-devices-not-included-in-the-french-list-of-products-and-services-qualifying-for-reimbursement-example-of-biologic-meshes
#1
A Sainfort, I Denis-Hallouard, G Aulagner, O Nuiry, X Armoiry
OBJECTIVES: To present a method aimed to evaluate the economic impact associated with the use of medical devices (DM) not reimbursed in addition to diagnosis related groups (DRGs) tariffs using the example of biological meshes for parietal reinforcement. METHODS: In this multicenter retrospective cohort study, we included all patients who received a biological mesh between January 2010-April 2014 (University hospitals of Saint-Étienne, France) or between January 2010-March 2015 (Lyon University hospitals, France)...
March 16, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28299927/supramolecular-hydrogels-based-on-dna-self-assembly
#2
Yu Shao, Haoyang Jia, Tianyang Cao, Dongsheng Liu
Extracellular matrix (ECM) provides essential supports three dimensionally to the cells in living organs, including mechanical support and signal, nutrition, oxygen, and waste transportation. Thus, using hydrogels to mimic its function has attracted much attention in recent years, especially in tissue engineering, cell biology, and drug screening. However, a hydrogel system that can merit all parameters of the natural ECM is still a challenge. In the past decade, deoxyribonucleic acid (DNA) has arisen as an outstanding building material for the hydrogels, as it has unique properties compared to most synthetic or natural polymers, such as sequence designability, precise recognition, structural rigidity, and minimal toxicity...
March 16, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28299156/fifty-shades-of-african-lightness-a-bio-psychosocial-review-of-the-global-phenomenon-of-skin-lightening-practices
#3
REVIEW
Meagan Jacobs, Susan Levine, Kate Abney, Lester Davids
Skin-lightening is an aesthetic practice of global concern. By adopting a biopsycho-social approach, we consider the interplay between the biological, psychological and social factors that underpin the circulation and consumption of skin lighteners in South Africa. This paper reflects on biological aspects of skin lightening, interpersonal relationships, individual beliefs and expectations about the maintenance of health and well being that informs cosmetic practices. The paper seeks to examine claims made by historians (Thomas) and political philosophers and activists (Biko) that colonialism and apartheid in South Africa historically reinforced the use of skin lightening products in the country...
December 31, 2016: Journal of Public Health in Africa
https://www.readbyqxmd.com/read/28293522/a-case-report-of-the-first-nonburn-related-military-trauma-victim-treated-with-spray-skin-regenerative-therapy-in-combination-with-a-dermal-regenerate-template
#4
Ian L Valerio, Daniel A Hammer, Juan L Rendon, Kerry P Latham, Mark E Fleming
Massive soft tissue and skin loss secondary to war-related traumas are among the most frequently encountered challenges in the care of wounded warriors. This case report outlines the first military nonburn-related trauma patient treated by a combination of regenerative modalities. Our case employs spray skin technology to an established dermal regenerate matrix. Our patient, a 29-year-old active duty male, suffered a combat blast trauma in 2010 while deployed. The patient's treatment course was complicated by a severe necrotizing fasciitis infection requiring over 100 surgical procedures for disease control and reconstruction...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28282003/complex-ventral-hernia-repair-with-acellular-dermal-matrices-clinical-and-quality-of-life-outcomes
#5
John Scott Roth, Amanda Zachem, Margaret A Plymale, Daniel L Davenport
Acellular dermal matrices (ADMs) are used in conjunction with complex hernia repair, but their efficacy is often debated. This study assesses clinical and quality of life (QOL) outcomes in multiply comorbid patients undergoing complex ventral hernia repair using ADMs. After obtaining institutional review board approval, a prospective study was conducted evaluating patients undergoing complex ventral incisional hernia repair with abdominal wall reconstruction (AWR) using either human (Flex HD) or porcine ADM (Strattice)...
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28280694/effectiveness-and-versatility-of-biological-prosthesis-in-transplanted-patients
#6
Giovanni Vennarecci, Gianluca Mascianà, Edoardo De Werra, Giovanni Battista Levi Sandri, Daniele Ferraro, Mirco Burocchi, Giovanni Tortorelli, Nicola Guglielmo, Giuseppe Maria Ettorre
AIM: To emphasize the effectiveness and versatility of prosthesis, and good tolerance by patients with incisional hernia (IH). METHODS: From December 2001 to February 2016, 270 liver transplantations were performed at San Camillo Hospital. IH occurred in 78 patients (28.8%). IH usually appeared early within the first year post-orthotopic liver transplantation. In the first era, fascial defect was repaired by primary closure for defects smaller than 2.5 cm or with synthetic mesh for greater defects...
February 24, 2017: World Journal of Transplantation
https://www.readbyqxmd.com/read/28277472/transvaginal-repair-of-complex-rectovaginal-fistulas-using-the-porcine-urinary-bladder-matrix-as-an-augmenting-graft
#7
Hemikaa Devakumar, Neeraja Chandrasekaran, Alexandriah Alas, Laura Martin, G Willy Davila, Eric Hurtado
BACKGROUND: After the US Food and Drug Administration issued a safety warning concerning vaginal mesh implants in 2008, their use in correction of pelvic floor defects have decreased in the United States (http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm479732.htm). However, we are still treating patients who have had complications associated with their use, rectovaginal fistulas (RVFs) being one of them. Rectovaginal fistulas are considered complex if greater than 2.5 cm, recurrent, associated with inflammatory bowel disease, or if they are proximal in location...
March 9, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28275427/resection-and-reconstruction-following-recurrent-malignant-phyllodes-case-report-and-review-of-literature
#8
Aashish Rajesh, Mohammed Farooq
INTRODUCTION: Phyllodes tumors are uncommon biphasic fibroepithelial neoplasms of the breast of varying malignant potential occurring in middle aged women. They exhibit diverse biological behavior. Margin free excision is the mainstay of treatment. CASE PRESENTATION: A 27 year-old lady was referred with a painless ulceroproliferative right breast lesion which had rapidly progressed over six months. Three years back, she had been diagnosed with a borderline phyllodes tumor and underwent a wide local excision followed by a right mastectomy for recurrence...
April 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28269609/knife-edge-scanning-microscopy-for-in-silico-study-of-cerebral-blood-flow-from-biological-imaging-data-to-flow-simulations
#9
Michael R Nowak, Alexander Lozovskiy, Dimitri Dobroskok, Yoonsuck Choe
Knife-edge scanning microscopy provides the capability to image whole-brain cerebral microvasculature of small organisms, such as mice, at sub-micron resolution, providing a feasible foundation for the reconstruction of circulatory pathways from the systemic to cellular scale. In this paper, we illustrate the feasibility of using this data to model cerebral blood flow using numerical simulations. Starting with a small vascular element in microcirculation of interest, we present its segmentation from the imaging-data volume, construction of its triangular surface mesh, assembly of its tetrahedral volumetric mesh from the surface, and then conclude with Stokes flow simulation of plasma through the microvascular vessel...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28265733/major-complex-abdominal-wall-repair-in-contaminated-fields-with-use-of-a-non-cross-linked-biologic-mesh-a-dual-institutional-experience
#10
J J Atema, E J Furnée, Y Maeda, J Warusavitarne, P J Tanis, W A Bemelman, C J Vaizey, M A Boermeester
BACKGROUND: Data on the use of biologic mesh in abdominal wall repair in complex cases remain sparse. Aim of this study was to evaluate a non-cross-linked porcine acellular dermal matrix for repair of complex contaminated abdominal wall defects. METHODS: Retrospective observational cohort study of consecutive patients undergoing abdominal wall repair with use of Strattice™ Reconstructive Tissue Matrix (LifeCell Corporation, Oxford, UK) between January 2011 and February 2015 at two National Intestinal Failure Units...
March 6, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28263160/-reconstructive-breast-surgery-using-implant-and-mesh
#11
Lene Nyhøj Heidemann, Gudjon Leifur Gunnarsson, Camilla Bille, Jens Ahm Sørensen, Jørn Bo Thomsen
The demand for reconstructive surgery after therapeutic and prophylactic mastectomy is increasing. The hammock technique for breast reconstruction was introduced in 2001 and provides support for the implant using either biologically derived or synthetic mesh. The material is formed as a hammock in the lower pole of the reconstructed breast, and due to its supportive capabilities it has been found to shorten the time needed for reconstruction, decrease the risk of capsular contracture and leave a superior aesthetic result...
March 6, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28260890/preparation-of-a-nano-and-micro-fibrous-decellularized-scaffold-seeded-with-autologous-mesenchymal-stem-cells-for-inguinal-hernia-repair
#12
Yinlong Zhang, Yuanyuan Zhou, Xu Zhou, Bin Zhao, Jie Chai, Hongyi Liu, Yifei Zheng, Jinling Wang, Yaozong Wang, Yilin Zhao
Prosthetic meshes used for hernioplasty are usually complicated with chronic pain due to avascular fibrotic scar or mesh shrinkage. In this study, we developed a tissue-engineered mesh (TEM) by seeding autologous bone marrow-derived mesenchymal stem cells onto nanosized fibers decellularized aorta (DA). DA was achieved by decellularizing the aorta sample sequentially with physical, mechanical, biological enzymatic digestion, and chemical detergent processes. The tertiary structure of DA was constituted with micro-, submicro-, and nanosized fibers, and the original strength of fresh aorta was retained...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28250803/medical-subject-heading-mesh-annotations-illuminate-maize-genetics-and-evolution
#13
Timothy M Beissinger, Gota Morota
BACKGROUND: High-density marker panels and/or whole-genome sequencing, coupled with advanced phenotyping pipelines and sophisticated statistical methods, have dramatically increased our ability to generate lists of candidate genes or regions that are putatively associated with phenotypes or processes of interest. However, the speed with which we can validate genes, or even make reasonable biological interpretations about the principles underlying them, has not kept pace. A promising approach that runs parallel to explicitly validating individual genes is analyzing a set of genes together and assessing the biological similarities among them...
2017: Plant Methods
https://www.readbyqxmd.com/read/28249103/a-hybrid-computational-model-to-explore-the-topological-characteristics-of-epithelial-tissues
#14
Ismael González-Valverde, José Manuel García Aznar
Epithelial tissues show a particular topology where cells resemble a polygon-like shape, but some biological processes can alter this tissue topology. During cell proliferation, mitotic cell dilation deforms the tissue and modifies the tissue topology. Additionally, cells are reorganized in the epithelial layer and these rearrangements also alter the polygon distribution. We present here a computer-based hybrid framework focused on the simulation of epithelial layer dynamics that combines discrete and continuum numerical models...
March 1, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28247120/bifurcation-analysis-of-reaction-diffusion-systems-on-arbitrary-surfaces
#15
Daljit Singh J Dhillon, Michel C Milinkovitch, Matthias Zwicker
In this paper, we present computational techniques to investigate the effect of surface geometry on biological pattern formation. In particular, we study two-component, nonlinear reaction-diffusion (RD) systems on arbitrary surfaces. We build on standard techniques for linear and nonlinear analysis of RD systems and extend them to operate on large-scale meshes for arbitrary surfaces. In particular, we use spectral techniques for a linear stability analysis to characterise and directly compose patterns emerging from homogeneities...
February 28, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28245360/patterning-three-dimensional-hydrogel-microenvironments-using-hyperbranched-polyglycerols-for-independent-control-of-mesh-size-and-stiffness
#16
Sara Pedron, Amanda M Pritchard, Gretchen A Vincil, Brenda Andrade, Steven C Zimmerman, Brendan A C Harley
The extracellular matrix is an environment rich with structural, mechanical, and molecular signals that can impact cell biology. Traditional approaches in hydrogel biomaterial design often rely on modifying the concentration of cross-linking groups to adjust mechanical properties. However, this strategy provides limited capacity to control additional important parameters in 3D cell culture such as microstructure and molecular diffusivity. Here we describe the use of multifunctional hyperbranched polyglycerols (HPGs) to manipulate the mechanical properties of polyethylene glycol (PEG) hydrogels while not altering biomolecule diffusion...
March 9, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28239943/unprecedented-complication-of-biologic-mesh-use-in-ventral-rectopexy
#17
Sean Leow, Frank Voyvodic, Elizabeth Murphy, Dayan de Fontgalland
No abstract text is available yet for this article.
February 27, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28239346/parallel-steps-large-scale-stochastic-spatial-reaction-diffusion-simulation-with-high-performance-computers
#18
Weiliang Chen, Erik De Schutter
Stochastic, spatial reaction-diffusion simulations have been widely used in systems biology and computational neuroscience. However, the increasing scale and complexity of models and morphologies have exceeded the capacity of any serial implementation. This led to the development of parallel solutions that benefit from the boost in performance of modern supercomputers. In this paper, we describe an MPI-based, parallel operator-splitting implementation for stochastic spatial reaction-diffusion simulations with irregular tetrahedral meshes...
2017: Frontiers in Neuroinformatics
https://www.readbyqxmd.com/read/28238041/electrospinning-of-bioactive-wound-healing-nets
#19
Heinz C Schröder, Emad Tolba, Bärbel Diehl-Seifert, Xiaohong Wang, Werner E G Müller
The availability of appropriate dressings for treatment of wounds, in particular chronic wounds, is a task that still awaits better solutions than provided by currently applied materials. The method of electrospinning enables the fabrication of novel materials for wound dressings due to the high surface area and porosity of the electrospun meshes and the possibility to include bioactive ingredients. Recent results show that the incorporation of biologically active inorganic polyphosphate microparticles and microspheres and synergistically acting retinoids into electrospun polymer fibers yields biocompatible and antibacterial mats for potential dressings with improved wound-healing properties...
2017: Progress in Molecular and Subcellular Biology
https://www.readbyqxmd.com/read/28228932/a-clinically-relevant-in-vivo-model-for-the-assessment-of-scaffold-efficacy-in-abdominal-wall-reconstruction
#20
Jeffrey Cy Chan, Krishna Burugapalli, Yi-Shiang Huang, John L Kelly, Abhay Pandit
An animal model that allows for assessment of the degree of stretching or contraction of the implant area and the in vivo degradation properties of biological meshes is required to evaluate their performance in vivo. Adult New Zealand rabbits underwent full thickness subtotal unilateral rectus abdominis muscle excision and were reconstructed with the non-biodegradable Peri-Guard(®), Prolene(®) or biodegradable Surgisis(®) meshes. Following 8 weeks of recovery, the anterior abdominal wall tissue samples were collected for measurement of the implant dimensions...
January 2017: Journal of Tissue Engineering
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