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Biologic mesh

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https://www.readbyqxmd.com/read/29155710/dna-nanotubes-as-a-versatile-tool-to-study-semiflexible-polymers
#1
Jörg Schnauß, Martin Glaser, Jessica S Lorenz, Carsten Schuldt, Christin Möser, Martin Sajfutdinow, Tina Händler, Josef A Käs, David M Smith
Mechanical properties of complex, polymer-based soft matter, such as cells or biopolymer networks, can be understood in neither the classical frame of flexible polymers nor of rigid rods. Underlying filaments remain outstretched due to their non-vanishing backbone stiffness, which is quantified via the persistence length (lp), but they are also subject to strong thermal fluctuations. Their finite bending stiffness leads to unique, non-trivial collective mechanics of bulk networks, enabling the formation of stable scaffolds at low volume fractions while providing large mesh sizes...
October 25, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29155333/ima-identifying-disease-related-genes-using-mesh-terms-and-association-rules
#2
Jeongwoo Kim, Changbae Bang, Hyeonseo Hwang, Doyoung Kim, Chihyun Park, Sanghyun Park
Genes play an important role in several diseases. Hence, in biology, identifying relationships between diseases and genes is important for the analysis of diseases, because mutated or dysregulated genes play an important role in pathogenesis. Here, we propose a method to identify disease-related genes using MeSH terms and association rules. We identified genes by analyzing the MeSH terms and extracted information on gene-gene interactions based on association rules. By integrating the extracted interactions, we constructed gene-gene networks and identified disease-related genes...
November 15, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29147580/molecular-age-related-changes-in-the-anterior-segment-of-the-eye
#3
REVIEW
Luis Fernando Hernandez-Zimbron, Rosario Gulias-Cañizo, María F Golzarri, Blanca Elizabeth Martínez-Báez, Hugo Quiroz-Mercado, Roberto Gonzalez-Salinas
Purpose: To examine the current knowledge about the age-related processes in the anterior segment of the eye at a biological, clinical, and molecular level. Methods: We reviewed the available published literature that addresses the aging process of the anterior segment of the eye and its associated molecular and physiological events. We performed a search on PubMed, CINAHL, and Embase using the MeSH terms "eye," "anterior segment," and "age." We generated searches to account for synonyms of these keywords and MESH headings as follows: (1) "Eye" AND "ageing process" OR "anterior segment ageing" and (2) "Anterior segment" AND "ageing process" OR "anterior segment" AND "molecular changes" AND "age...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29131387/laparoscopic-mesh-repair-of-a-labial-hernia
#4
Philippe Grange, Fevzi Shakir, Ganesh Thiagamoorthy, George Araklitis, Dudley Robinson, Linda Cardozo
AIMS: To present a narrated video designed to demonstrate the steps involved in a laparoscopic mesh repair of a labial hernia. METHODS: This was in a 76-year-old woman who presented with a small bowel hernia in to her left labium majus. In 2014 she had a robotically assisted radical cystectomy for bladder cancer with anterior exenteration. She developed the hernia in February 2015 and initially a vaginal approach was attempted to repair the hernia (with layered non-absorbable sutures to close the fascia over the defect) at her local hospital, although this was unsuccessful...
November 13, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29130596/evaluation-of-a-bioengineered-construct-for-tissue-engineering-applications
#5
Perla Ayala, Erbin Dai, Michael Hawes, Liying Liu, Ovijit Chaudhuri, Carolyn A Haller, David J Mooney, Elliot L Chaikof
Effective biomaterial options for tissue repair and regeneration are limited. Current biologic meshes are derived from different tissue sources and are generally sold as decellularized tissues. This work evaluated two collagen based bioengineered constructs and a commercial product in a model of abdominal full thickness defect repair. To prepare the bioengineered construct, collagen type 1 from porcine skin was isolated using an acid solubilization method. After purification, the collagen was formed into collagen sheets that were physically bonded to form a mechanically robust construct that was subsequently laser micropatterned with pores as a means to promote tissue integration (collagen only construct)...
November 11, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29130235/-a-meta-analysis-on-risk-factors-of-postoperative-perineal-wound-complications-after-abdominoperineal-resection-for-rectal-cancer
#6
Senqi Lu, Xiaofeng Chang, Xiaodong Yang, Decai Yu, Qigen Huang, Feng Wang
OBJECTIVE: To investigate the risk factors of postoperative perineal wound complications after abdominoperineal resection for rectal cancer. METHODS: The databases of Medline, Embase, Web of Science, Ovid, Cochrane Library, CBM, CNKI, VIP and WANFANG were searched for the studies of abdominoperineal resection up to October 2016. The quality of the included studies was assessed by using "Cochrane collaboration's tool for assessing risk of bias" and "the Newcastle-Ottawa Scale"...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29081541/a-continuum-mechanics-based-musculo-mechanical-model-for-esophageal-transport
#7
Wenjun Kou, Boyce E Griffith, John E Pandolfino, Peter J Kahrilas, Neelesh A Patankar
In this work, we extend our previous esophageal transport model using an immersed boundary (IB) method with discrete fiber-based structural model, to one using a continuum mechanics-based model that is approximated based on finite elements (IB-FE). To deal with the leakage of flow when the Lagrangian mesh becomes coarser than the fluid mesh, we employ adaptive interaction quadrature points to deal with Lagrangian-Eulerian interaction equations based on a previous work (Griffith and Luo [1]). In particular, we introduce a new anisotropic adaptive interaction quadrature rule...
October 1, 2017: Journal of Computational Physics
https://www.readbyqxmd.com/read/29080723/no-351-transvaginal-mesh-procedures-for-pelvic-organ-prolapse
#8
Maryse Larouche, Roxana Geoffrion, Jens-Erik Walter
OBJECTIVE: This guideline reviews the evidence related to the risks and benefits of using transvaginal mesh in pelvic organ prolapse repairs in order to update recommendations initially made in 2011. INTENDED USERS: Gynaecologists, residents, urologists, urogynaecologists, and other health care providers who assess, counsel, and care for women with pelvic organ prolapse. TARGET POPULATION: Adult women with symptomatic pelvic organ prolapse considering surgery and those who have previously undergone transvaginal mesh procedures for the treatment of pelvic organ prolapse...
November 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29080660/indications-and-controversies-for-implant-based-breast-reconstruction-utilizing-biological-meshes
#9
REVIEW
Michael R Zenn
The advent of acellular dermal matrices (ADMs) has changed the way implant reconstruction is performed and has opened the door to muscle-sparing techniques that can be performed as an NSM (nipple-sparing mastectomy) with DTI (direct to implant) with excellent cosmesis and less patient morbidity. The article discusses differences in types of ADMs and outlines some current strategies and controversies with ADM use.
January 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29078909/infection-prevention-using-affinity-polymer-coated-synthetic-meshes-in-a-pig-hernia-model
#10
Jeffrey A Blatnik, Thimma R Thatiparti, David M Krpata, Sean T Zuckerman, Michael J Rosen, Horst A von Recum
BACKGROUND: Given concern for hernia mesh infection, surgeons often use biologic mesh which may provide reduced risk of infection but at the cost of decreased repair durability. We evaluated mesh coating to provide sustained release of antibiotics to prevent prosthetic mesh infection and also allow a durable repair. MATERIALS AND METHODS: Cyclodextrin-based polymer was crosslinked onto multifilament polyester mesh and loaded with vancomycin (1.75 mg/cm(2)). Pigs received modified meshes (n = 6) or normal, untreated meshes (n = 4), which were implanted into acute 10 × 5 cm ventral hernia, then directly inoculated with 10(6) colony-forming unit (CFU) of methicillin-resistant Staphylococcus aureus (MRSA)...
November 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/29078657/materials-and-techniques-in-chest-wall-reconstruction-a-review
#11
REVIEW
Stefano Sanna, Jury Brandolini, Alessandro Pardolesi, Desideria Argnani, Marta Mengozzi, Andrea Dell'Amore, Piergiorgio Solli
Extensive chest wall resection and reconstruction are a challenging procedure that requires a multidisciplinary approach, including input from thoracic surgeon, plastic surgeon and oncologist. In particular chest wall neoplastic pathology is associated with high surgical morbidity and can result in full thickness defects hard to reconstruct. The goals of a successful chest wall reconstruction are to restore the chest wall rigidity, preserve pulmonary mechanic and protect the intrathoracic organs minimizing the thoracic deformity...
2017: J Vis Surg
https://www.readbyqxmd.com/read/29075631/commentary-evidence-for-replacement-of-an-infected-synthetic-by-a-biological-mesh-in-abdominal-wall-hernia-repair
#12
COMMENT
Ekaterini Christina Tampaki, Athanasios Tampakis, Konstantinos Kontzoglou, Gregory Kouraklis
No abstract text is available yet for this article.
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29064920/what-s-new-in-acellular-dermal-matrix-and-soft-tissue-support-for-prosthetic-breast-reconstruction
#13
REVIEW
John Y S Kim, Alexei S Mlodinow
Of the nearly 90,000 implant-based breast reconstructions performed in the United States, the majority use internal soft-tissue support. Aesthetically, these constructs may allow for better positioning of prosthesis, improve lower pole expansion, and increase projection. They may have particular utility in direct-to-implant, nipple-sparing mastectomies, and prepectoral reconstructions. In recent years, new permutations of acellular dermal matrices have evolved with diverse shapes, sizes, form-factor innovations, and processing characteristics...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29064502/phase-behaviour-of-disordered-proteins-underlying-low-density-and-high-permeability-of-liquid-organelles
#14
Ming-Tzo Wei, Shana Elbaum-Garfinkle, Alex S Holehouse, Carlos Chih-Hsiung Chen, Marina Feric, Craig B Arnold, Rodney D Priestley, Rohit V Pappu, Clifford P Brangwynne
Many intracellular membraneless organelles form via phase separation of intrinsically disordered proteins (IDPs) or regions (IDRs). These include the Caenorhabditis elegans protein LAF-1, which forms P granule-like droplets in vitro. However, the role of protein disorder in phase separation and the macromolecular organization within droplets remain elusive. Here, we utilize a novel technique, ultrafast-scanning fluorescence correlation spectroscopy, to measure the molecular interactions and full coexistence curves (binodals), which quantify the protein concentration within LAF-1 droplets...
November 2017: Nature Chemistry
https://www.readbyqxmd.com/read/29063566/clinical-research-informatics-contributions-from-2016
#15
C Daniel, R Choquet
Objectives: To summarize key contributions to current research in the field of Clinical Research Informatics (CRI) and to select the best papers published in 2016. Methods: A bibliographic search using a combination of MeSH and free terms on CRI was performed using PubMed, followed by a double-blind review in order to select a list of candidate best papers to be then peer-reviewed by external reviewers. A consensus meeting between the two section editors and the editorial team was organized to finally conclude on the selection of best papers...
August 2017: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/29061321/robotic-parastomal-hernia-repair-with-biologic-mesh
#16
Peter Mekhail, Akbar Ashrafi, Mario Mekhail, David Hatcher, Monish Aron
INTRODUCTION: Parastomal hernia is a common and vexing problem after ileal conduit urinary diversion that can cause pain, bowel symptoms, and problems with the stoma appliance, resulting in leakage, odor, and impairment of quality of life. Historically, these hernias have been managed open surgically, which requires considerable dissection of the abdominal wall for mesh placement, and may also require relocating the stoma to the contralateral side. Further, open parastomal hernia repair can be a morbid procedure with recurrence rates of approximately 30%...
September 7, 2017: Urology
https://www.readbyqxmd.com/read/29060827/a-framework-for-simulating-gastric-electrical-propagation-in-confocal-microscopy-derived-geometries
#17
Berit Krohn, Shameer Sathar, Oliver Rohrle, Jean-Marie Vanderwinden, Gregory O'Grady, Leo K Cheng
Interstitial Cells of Cajal (ICC) initiate and actively propagate electrical events in the gastrointestinal tract known as slow-waves. The slow-waves coordinate the contraction of the gastrointestinal tract necessary for breakdown and mixing of ingested food. Degradation of the ICC numbers has been linked to several gastrointestinal motility disorders. However, limitations in imaging techniques and techniques for the quantification of ICC network structure have hindered our understanding of these disorders...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29059608/use-of-biologic-mesh-at-ostomy-takedown-to-prevent-incisional-hernia-a-case-series
#18
Sepehr Lalezari, Michael L Caparelli, Shyam Allamaneni
INTRODUCTION: Incisional hernias are a relatively common occurrence after ostomy takedown with a incidence of 30-35%. The use of biologic mesh offers a means to bolster the stoma incision site with a lower risk of infection than synthetic mesh. METHODS: This study represents a retrospective chart review of six patients who underwent stoma takedown and had biologic mesh placed in the retrorectus position during repair from March 2015 until March 2016. RESULTS: There has been a zero-rate of hernia occurrence for the six patients who underwent stoma takedown...
October 6, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29043107/the-intervals-method-a-new-approach-to-analyse-finite-element-outputs-using-multivariate-statistics
#19
Jordi Marcé-Nogué, Soledad De Esteban-Trivigno, Thomas A Püschel, Josep Fortuny
BACKGROUND: In this paper, we propose a new method, named the intervals' method, to analyse data from finite element models in a comparative multivariate framework. As a case study, several armadillo mandibles are analysed, showing that the proposed method is useful to distinguish and characterise biomechanical differences related to diet/ecomorphology. METHODS: The intervals' method consists of generating a set of variables, each one defined by an interval of stress values...
2017: PeerJ
https://www.readbyqxmd.com/read/29030837/totally-robotic-combined-roux-en-y-gastric-bypass-and-hiatal-hernia-repair-with-biological-mesh-technical-points
#20
Fabian Reche, Adrian Mancini, Anne-Laure Borel, Jean-Luc Faucheron, Catherine Arvieux
No abstract text is available yet for this article.
October 13, 2017: Obesity Surgery
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