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Biologic mesh

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https://www.readbyqxmd.com/read/28541865/multipoint-suture-fixation-technique-for-abdominal-wall-reconstruction-with-component-separation-and-onlay-biological-mesh-placement
#1
Brad Denney, Jorge I de la Torre
Component separation with mesh reinforcement has become the primary modality for complex abdominal wall reconstruction. However, many fundamental questions remain unanswered, such as whether underlay versus overlay mesh placement is superior, and what is the best means of suture fixation technique for mesh placement? This study presents the senior author's technique for onlay biologic mesh placement with multipoint suture fixation in combination with component separation and its subsequent low recurrence rates...
May 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28532087/the-repairing-of-full-thickness-skin-deficiency-and-its-biological-mechanism-using-decellularized-human-amniotic-membrane-as-the-wound-dressing
#2
Mengsheng Song, Weiqing Wang, Qihua Ye, Shizhong Bu, Zhisen Shen, Yabin Zhu
Human amniotic membrane (HAM) was a biocompatible scaffold with advantages of anti-inflammatory, low antigen, feasibility, tolerance and low cost. In our previous work, HAM was treated to be decellularized using surfactant, lipase and DNAase methods and the efficacy as an implantable biological mesh was verified after decellularization treatment. In this work, we used the previous protocol to decellularize the fresh HAM, and applied it to repair full-thickness skin defects with Sprague-Dawley rats as the test animals...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28526657/risk-adjusted-adverse-outcomes-in-complex-abdominal-wall-hernia-repair-with-biologic-mesh-a-case-series-of-140-patients
#3
Rifat Latifi, David Samson, Ansab Haider, Asad Azim, Hajira Iftikhar, Bellal Joseph, Elizabeth Tilley, Jorge Con, Saranda Gashi, Ayman El-Menyar
INTRODUCTION: Biologic mesh is preferred for repair of complex abdominal wall hernias (CAWHs) in patients at high risk of wound infection. We aimed to identify predictors of adverse outcomes after complex abdominal wall hernia repair (CAWR) using biologic mesh with different placement techniques and under different surgical settings. METHODS: A retrospective case series study was conducted on all patients who underwent CAWR with biologic mesh between 2010 and 2015 at a tertiary medical center...
May 16, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28523363/systematic-review-and-meta-analysis-of-laparoscopic-mesh-versus-suture-repair-of-hiatus-hernia-objective-and-subjective-outcomes
#4
Chao Zhang, Diangang Liu, Fei Li, David I Watson, Xiang Gao, Jan H Koetje, Tao Luo, Chao Yan, Xing Du, Zhonggao Wang
BACKGROUND: Hiatus hernia (HH) contributes to the pathophysiology of gastroesophageal reflux disease (GERD). Mesh-augmentation of surgical repair might be associated with a reduced risk of recurrence and GERD. However, recurrence rates, mesh-associated complications and quality of life (QOL) after mesh versus suture repair are debated. The aim of this meta-analysis was to determine HH recurrence following mesh-augmentation versus suture repair. Secondary aims were to compare complications, mortality, QOL and GERD symptoms following different repair techniques...
May 18, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28518080/rearing-ixodes-scapularis-the-black-legged-tick-feeding-immature-stages-on-mice
#5
Andrew B Nuss, Manoj G Mathew, Monika Gulia-Nuss
Ixodes scapularis, the vector of Lyme disease, is one of the most important disease vectors in the eastern and Midwestern United States. This species is a three host tick that requires a blood meal from a vertebrate host for each development stage, and the adult females require a blood meal for reproduction. Larval ticks attach to their host for 3 - 5 days for feeding and drop off the host when fully engorged. This dependency on several different hosts and the lengthy attachment time for engorgement complicates tick rearing in the laboratory setting...
May 8, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28508281/perineal-hernia-repair-after-abdominoperineal-excision-or-extralevator-abdominoperineal-excision-a-systematic-review-of-the-literature
#6
REVIEW
A Balla, G Batista Rodríguez, N Buonomo, C Martinez, P Hernández, J Bollo, E M Targarona
BACKGROUND: The incidence of perineal hernia after abdominoperineal excision and extralevator abdominoperineal excision ranges from 1 to 26%. In this systematic review, we compared surgical options and postoperative outcomes of perineal hernia repair in this setting from 2012 to 2016 with findings in a review of publications 1944-2011. METHODS: We searched the PubMed database using the keywords "hernia" AND "perineum" identified 392 papers published from 1946 to 2016...
May 15, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28503515/synthetic-versus-biological-mesh-related-erosion-after-laparoscopic-ventral-mesh-rectopexy-a-systematic-review
#7
REVIEW
Andrea Balla, Silvia Quaresima, Sebastian Smolarek, Mostafa Shalaby, Giulia Missori, Pierpaolo Sileri
PURPOSE: This review reports the incidence of mesh-related erosion after ventral mesh rectopexy to determine whether any difference exists in the erosion rate between synthetic and biological mesh. METHODS: A systematic search of the MEDLINE and the Ovid databases was conducted to identify suitable articles published between 2004 and 2015. The search strategy capture terms were laparoscopic ventral mesh rectopexy, laparoscopic anterior rectopexy, robotic ventral rectopexy, and robotic anterior rectopexy...
April 2017: Annals of Coloproctology
https://www.readbyqxmd.com/read/28492357/long-term-effectiveness-of-strattice-in-the-laparoscopic-closure-of-paraesophageal-hernias
#8
Daniel Lomelin, Alicia Smith, Nathan Bills, Amareshewar Chiruvella, Christopher Crawford, Crystal Krause, Robert Bayer, Dmitry Oleynikov
Prosthetic reinforcement reduces the recurrence rate of large paraesophageal hernias (PEH), but the use of synthetic or biosynthetic mesh in the repair remains controversial. PEH repair has reported recurrence rates of 12% to 42%, and primary repair of PEH by suture closure under tension is at high risk of disruption. Synthetic mesh use in large PEH repair has shown to reduce recurrence but can lead to problems including mesh erosion, ulceration, stricture, and dysphagia. The objective of this study was to examine the long-term safety and efficacy of Strattice biologic mesh, a porcine acellular dermal matrix, in crural reinforcement of laparoscopic large PEH repair...
June 2017: Surgical Innovation
https://www.readbyqxmd.com/read/28487815/phospholipid-arrays-on-porous-polymer-coatings-generated-by-micro-contact-spotting
#9
Sylwia Sekula-Neuner, Monica de Freitas, Lea-Marie Tröster, Tobias Jochum, Pavel A Levkin, Michael Hirtz, Harald Fuchs
Nanoporous poly(2-hydroxyethyl methacrylate-co-ethylene dimethacrylate) (HEMA-EDMA) is used as a 3D mesh for spotting lipid arrays. Its porous structure is an ideal matrix for lipid ink to infiltrate, resulting in higher fluorescent signal intensity as compared to similar arrays on strictly 2D substrates like glass. The embedded lipid arrays show high stability against washing steps, while still being accessible for protein and antibody binding. To characterize binding to polymer-embedded lipids we have applied Streptavidin as well as biologically important biotinylated androgen receptor binding onto 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(cap biotinyl) (Biotinyl Cap PE) and anti-DNP IgE recognition of 2,4-dinitrophenyl[1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[6-[(2,4-dinitrophenyl)amino]hexanoyl] (DNP)] antigen...
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/28482606/microarc-oxidation-coating-covered-ti-implants-with-micro-scale-gouges-formed-by-a-multi-step-treatment-for-improving-osseointegration
#10
Yixin Bai, Rui Zhou, Jianyun Cao, Daqing Wei, Qing Du, Baoqiang Li, Yaming Wang, Dechang Jia, Yu Zhou
The sub-microporous microarc oxidation (MAO) coating covered Ti implant with micro-scale gouges has been fabricated via a multi-step MAO process to overcome the compromised bone-implant integration. The as-prepared implant has been further mediated by post-heat treatment to compare the effects of -OH functional group and the nano-scale orange peel-like morphology on osseointegration. The bone regeneration, bone-implant contact interface, and biomechanical push-out force of the modified Ti implant have been discussed thoroughly in this work...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28464362/long-term-follow-up-of-anterior-vaginal-repair-a-comparison-among-colporrhaphy-colporrhaphy-with-reinforcement-by-xenograft-and-mesh
#11
Matteo Balzarro, Emanuele Rubilotta, Antonio B Porcaro, Nicolò Trabacchin, Alessandra Sarti, Maria A Cerruto, Salvatore Siracusano, Walter Artibani
AIMS: To assess the long-term complications and outcomes in patients treated for pelvic organ prolapse (POP) with transvaginal anterior colporrhaphy (AC) alone, transvaginal naterior AC with reinforcement by using porcine Xenograft (AC-P) (Pelvisoft® Biomesh), and transvaginal anterior repair with polypropylene mesh (AC-M). METHODS: This was a retrospective analysis of 109/123 consecutive patients, who underwent cystocele repair: 42 AC, 19 AC-P, and 48 AC-M. Subjective outcomes included validated questionnaires as well as questions that had not been previously validated...
May 2, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28460203/deep-ssi-after-mesh-mediated-groin-hernia-repair-management-and-outcome-in-an-emergency-surgery-department
#12
G Salamone, L Licari, G Augello, S Campanella, N Falco, R Tutino, G Cocorullo, R Gullo, C Raspanti, P De Marco, C Porrello, G Profita, G Gulotta
AIM: Mesh-mediated groin hernia repair is considered the goldstandard procedure. It has low recurrence rate. Rarely a deep Surgical Site Infection (SSI) is seen when a synthetic prosthesis is used. CASE REPORT: We describe a rare case of bilateral deep SSI after mesh-mediated groin hernia repair. Diagnosis was performed through the physical examination and radiological exams. Microbiological samples identified a methicillin-resistant Staphylococcus aureus responsible of the infection...
January 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/28457335/characterization-of-ventral-incisional-hernia-and-repair-using-shear-wave-elastography
#13
Anuj Chaudhry, Joseph S Fernandez-Moure, Peer Shafeeq Shajudeen, Jeffrey L Van Eps, Fernando J Cabrera, Bradley K Weiner, Brian J Dunkin, Ennio Tasciotti, Raffaella Righetti
BACKGROUND: To assess the integrity of hernia repair, imaging modalities such as computed tomography or ultrasound (US) are commonly used. Neither modality has currently the capacity to simultaneously image the mesh and quantify a prosthetic and surrounding tissue stiffness. In this pilot study, we hypothesize that US shear wave elastography (SWE) can be used to identify a polyester mesh and a biologic graft and to assess their stiffness noninvasively in a rat model of bridging hernia repair...
April 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28455098/computing-osmotic-permeabilities-of-aquaporins-aqp4-aqp5-and-glpf-from-near-equilibrium-simulations
#14
Thierry O Wambo, Roberto A Rodriguez, Liao Y Chen
Measuring or computing the single-channel permeability of aquaporins/aquaglyceroporins (AQPs) has long been a challenge. The measured values scatter over an order of magnitude but the corresponding Arrhenius activation energies converge in the current literature. Osmotic flux through an AQP was simulated as water current forced through the channel by kilobar hydraulic pressure or theoretically approximated as single-file diffusion. In this paper, we report large scale simulations of osmotic current under sub M gradient through three AQPs (water channels AQP4 and AQP5 and glycerol-water channel GlpF) using the mature particle mesh Ewald technique (PME) for which the established force fields have been optimized with known accuracy...
April 25, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28451705/demonstration-of-a-box-stitch-technique-for-laparoscopic-uterosacral-ligament-suspension
#15
Allison M Wyman, Lindsey Hahn, Emad Mikhail, Stuart Hart
AIM: We demonstrate a novel box stitch technique of laparoscopic post-hysterectomy uterosacral ligament suspension for apical prolapse in restorative pelvic reconstructive surgery. MATERIAL AND METHODS: We present a case of a 58yo female with symptomatic stage III pelvic organ prolapse with a history of a total abdominal hysterectomy 30 years prior. She strongly desired the usage of no synthetic or biologic mesh for her restorative surgical repair. This video provides a step-by-step guide on how to perform a laparoscopic box stitch as a technique for uterosacral ligament suspension as an apical native tissue option for patients with the need for post hysterectomy apical prolapse...
April 27, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28444543/cost-analysis-of-incisional-hernia-repair-with-synthetic-mesh-and-biological-mesh-an-italian-study
#16
Sabrina Rampado, Andrea Geron, Giovanni Pirozzolo, Angelica Ganss, Elisa Pizzolato, Romeo Bardini
Repair of an incisional hernia (IH) generates costs on several levels and domains of society. The aim of this study was to make a complete cost analysis of incisional hernia repair (IHR) with synthetic and biological mesh and to compare it with financial reimbursement. Patients were grouped into three levels to determine the complexity of their care, and hence, the costs involved. Group 1 included patients without comorbidities, who underwent a "standard" incisional hernia repair (SIHR), with synthetic mesh...
April 25, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28425679/soft-interactions-and-volume-exclusion-by-polymeric-crowders-can-stabilize-or-destabilize-transient-structure-in-disordered-proteins-depending-on-polymer-concentration
#17
Farai I Rusinga, David D Weis
The effects of macromolecular crowding on the transient structure of intrinsically disordered proteins is not well-understood. Crowding by biological molecules inside cells could modulate transient structure and alter IDP function. Volume exclusion theory and observations of structured proteins suggest that IDP transient structure would be stabilized by macromolecular crowding. Amide hydrogen exchange (HX) of IDPs in highly concentrated polymer solutions would provide valuable insights into IDP transient structure under crowded conditions...
April 20, 2017: Proteins
https://www.readbyqxmd.com/read/28419245/support-of-the-aortic-wall-a-histological-study-in-sheep-comparing-a-macroporous-mesh-with-low-porosity-vascular-graft-of-the-same-polyethylene-terephthalate-material
#18
Lucas Van Hoof, Peter Verbrugghe, Erik Verbeken, Tom Treasure, Nele Famaey, Bart Meuris, Paul Herijgers, Filip Rega
OBJECTIVES: Wrapping with various materials was an early treatment for aortic aneurysms. Wrapping with low-porosity vascular grafts has been associated with graft migration and vascular erosion. An alternative is to use a macroporous mesh (MPM) made of the same polymer (polyethylene terephalate). We compared the histological outcome 1 year after wrapping sheep aortas with low-porosity grafts versus MPM fabrics. METHODS: The 2 different fabrics were wrapped around the aorta of 3 sheep...
April 16, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28417997/iterative-expansion-microscopy
#19
Jae-Byum Chang, Fei Chen, Young-Gyu Yoon, Erica E Jung, Hazen Babcock, Jeong Seuk Kang, Shoh Asano, Ho-Jun Suk, Nikita Pak, Paul W Tillberg, Asmamaw T Wassie, Dawen Cai, Edward S Boyden
We recently developed a method called expansion microscopy, in which preserved biological specimens are physically magnified by embedding them in a densely crosslinked polyelectrolyte gel, anchoring key labels or biomolecules to the gel, mechanically homogenizing the specimen, and then swelling the gel-specimen composite by ∼4.5× in linear dimension. Here we describe iterative expansion microscopy (iExM), in which a sample is expanded ∼20×. After preliminary expansion a second swellable polymer mesh is formed in the space newly opened up by the first expansion, and the sample is expanded again...
April 17, 2017: Nature Methods
https://www.readbyqxmd.com/read/28413333/equilibrium-shapes-of-a-heterogeneous-bubble-in-an-electric-field-a-variational-formulation-and-numerical-verifications
#20
Hanxiong Wang, Liping Liu, Dong Liu
The equilibrium shape of a bubble/droplet in an electric field is important for electrowetting over dielectrics (EWOD), electrohydrodynamic (EHD) enhancement for heat transfer and electro-deformation of a single biological cell among others. In this work, we develop a general variational formulation in account of electro-mechanical couplings. In the context of EHD, we identify the free energy functional and the associated energy minimization problem that determines the equilibrium shape of a bubble in an electric field...
March 2017: Proceedings. Mathematical, Physical, and Engineering Sciences
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