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Dehydration and breastfeeding

Nilofer Salim Mujawar, Archana Nirmal Jaiswal
AIMS AND OBJECTIVES: Evaluation of neonatal hypernatremia and hypernatremic dehydration in neonates receiving exclusive breastfeeding. INTRODUCTION: Neonatal hypernatremia is a serious condition in the newborn period. We present infants with hypernatremic dehydration due to breast milk (BM) hypernatremia. Hypernatremic dehydration in breast-fed newborns is usually secondary to insufficient lactation. We present the neonatal hypernatremia and hypernatremic dehydration encountered between January and December, 2012, its causes and treatment...
January 2017: Indian Journal of Critical Care Medicine
Suzanne Boer, Sevim Unal, Jacobus P van Wouwe, Paula van Dommelen
BACKGROUND: Neonatal hypernatremic dehydration is prevented by daily neonatal weight monitoring. We aim to provide evidence-based support of this universally promoted weighing policy and to establish the most crucial days of weighing. METHODS: Weight measurements of 2,359 healthy newborns and of 271 newborns with clinical hypernatremic dehydration were used within the first seven days of life to simulate various weighting policies to prevent hypernatremic dehydration; its sensitivity, specificity and positive predictive value (PPV) of these policies were calculated...
2016: PloS One
Despina D Briana, Maria Boutsikou, Theodora Boutsikou, Antonios Marmarinos, Dimitrios Gourgiotis, Ariadne Malamitsi-Puchner
OBJECTIVE: To determine maternal colostrum/serum concentrations of the bioactive substances irisin, adropin and copeptin and investigate their association with several perinatal parameters and pathologic conditions during pregnancy. METHODS: In a cohort of 81 mothers with full-term deliveries, colostrum/serum concentrations of irisin, adropin and copeptin were prospectively evaluated by ELISA on Day 3-4 postpartum. RESULTS: Copeptin and adropin were detectable in human colostrum at higher, while irisin at lower concentrations than in maternal serum (p < 0...
March 2017: Journal of Maternal-fetal & Neonatal Medicine
Sushmita Das, Ganesh Chandra Sahoo, Pradeep Das, Utpal Kant Singh, Anil Kumar Jaiswal, Prachi Singh, Ranjeet Kumar, Rishikesh Kumar
OBJECTIVES: To evaluate the contribution of breastfeeding to Rotavirus (RV)-induced antigenemia and/or RNAemia and disease severity in Indian children (<2 yrs age). METHODS: Paired stool and serum samples were collected from (a) hospitalized infants with diarrhea (n = 145) and (b) healthy control infants without diarrhea (n = 28). Stool RV-antigen was screened in both groups by commercial rapid-test and enzyme immunoassay. The disease severity was scored and real-time-PCR was used for viral-load estimation...
2016: PloS One
Dwi Prasetyo, Iesje Martiza Sabaroedin, Yudith Setiati Ermaya, Yati Soenarto
Background. Rotavirus is the leading cause of severe acute diarrhea in children. Infants who are exclusively breastfed develop fewer infections and have less severe illnesses. This study aimed to determine association between severe dehydration in rotavirus diarrhea and exclusive breastfeeding. Methods. This is a cross-sectional study in infants ≤ 6 months old with acute diarrhea in Dr. Hasan Sadikin Hospital, Bandung, Indonesia. Results. From 134 infants ≤ 6 months old with acute diarrhea enrolled from April 2009 to December 2012, there were 88 (65...
2015: Journal of Tropical Medicine
Pedro Marques, Kavinga Gunawardana, Ashley Grossman
UNLABELLED: Gestational diabetes insipidus (DI) is a rare complication of pregnancy, usually developing in the third trimester and remitting spontaneously 4-6 weeks post-partum. It is mainly caused by excessive vasopressinase activity, an enzyme expressed by placental trophoblasts which metabolises arginine vasopressin (AVP). Its diagnosis is challenging, and the treatment requires desmopressin. A 38-year-old Chinese woman was referred in the 37th week of her first single-gestation due to polyuria, nocturia and polydipsia...
2015: Endocrinology, Diabetes & Metabolism Case Reports
Maja Verena Nielsen, Solomon Amemasor, Alex Agyekum, Wibke Loag, Florian Marks, Nimako Sarpong, Denise Dekker, Yaw Adu-Sarkodie, Jürgen May
Differentiation of infectious causes in severely ill children is essential but challenging in sub- Saharan Africa. The aim of the study was to determine clinical indicators that are able to identify bacterial co-infections in P. falciparum infected children in rural Ghana. In total, 1,915 severely ill children below the age of 15 years were recruited at Agogo Presbyterian Hospital in Ghana between May 2007 and February 2011. In 771 (40%) of the children malaria parasites were detected. This group was analyzed for indicators of bacterial co-infections using bivariate and multivariate regression analyses with 24 socio-economic variables, 16 terms describing medical history and anthropometrical information and 68 variables describing clinical symptoms...
2015: PloS One
Yuri Fc Dos Santos, Jailson de B Correia, Ana R Falbo
BACKGROUND: The World Health Organization stresses the need for training families in the adequate management of acute diarrhoea to reduce child mortality and morbidity. This study analysed caregiver knowledge about diarrhoea prevention and management in north-east Brazil. METHODS: Cross-sectional study of 213 children aged under 5 years treated at a public emergency department in Pernambuco, Brazil. Caregiver knowledge was assessed with a questionnaire. RESULTS: Caregivers believed that breastfeeding until age 6 months, not using tap water for food preparation, vaccination against rotavirus and other diseases help prevent diarrhoea...
April 2015: Tropical Doctor
Asher Rosinger
OBJECTIVES: The purpose of this study was to compare hydration status between lactating and non-lactating women in the hot-humid Amazon. METHODS: Fifty-four women (15-81 years) from two villages at different distances to the market provided urine samples, anthropometric measurements, and health recalls. Urine samples were analyzed for urine specific gravity (USG). Bivariate and multiple linear and logistic regressions tested differences in USG and dehydration (USG > 1...
July 2015: American Journal of Human Biology: the Official Journal of the Human Biology Council
Fabian Bock, Katrin Borucki, Peter Vorwerk, Ronald Biemann, Berend Isermann
BACKGROUND: Anemia is a common presentation in children but the differential diagnosis of iron deficiency and β-thalassemia remains a diagnostic challenge. Red blood cell indices have been shown to perform weakly in such scenarios. One potential cause is breastfeeding, but the evidence for unusually prolonged exclusive breastfeeding as a cause of iron deficiency anemia in older (>2 years) toddlers is sparse and the association of breastfeeding with iron deficiency in this age group of older toddlers is not unequivocally established...
2014: BMC Research Notes
Maria Pia De Carolis, Carmen Cocca, Elisabetta Valente, Serafina Lacerenza, Serena Antonia Rubortone, Antonio Alberto Zuppa, Costantino Romagnoli
BACKGROUND: Early discharge of mother/neonate dyad has become a common practice, and its effects are measured by readmission rates. We evaluated the safety of early discharge followed by an individualized Follow-up programme and the efficacy in promoting breastfeeding initiation and duration. METHODS: During a nine-month period early discharge followed by an early targeted Follow-up was carried out in term neonates in the absence of weight loss <10% or hyperbilirubinaemia at risk of treatment...
2014: Italian Journal of Pediatrics
Chizoma M Ndikom, Bukola Fawole, Roslyn E Ilesanmi
BACKGROUND: Breastfeeding is known to be the biological norm. Despite this, many women wean their babies because of perceived insufficient breast milk production. Mothers are sometimes advised to increase their fluid intake in the hope that this could improve breast milk production. The effect of extra fluid on human breast milk production is not well established, however. OBJECTIVES: To assess the effect of extra fluid for breastfeeding mothers on milk production/supply and infant growth...
2014: Cochrane Database of Systematic Reviews
Paula van Dommelen, Suzanne Boer, Sevim Unal, Jacobus P van Wouwe
BACKGROUND: Most breast-fed newborns get the milk they need. However, very rarely milk intake is insufficient mostly as a result of poor breastfeeding techniques. Dramatic weight loss and hypernatremic dehydration may occur. Our aim was to construct charts for weight loss. METHODS: A case-control study was performed. Charts with standard deviation score (SDS) lines for weight loss in the first month were constructed for 2,359 healthy breast-fed term newborns and 271 cases with breastfeeding-associated hypernatremic dehydration with serum sodium level > 149 mEq/L...
June 2014: Birth
Hendra Salim, I Putu Gede Karyana, I Gusti Ngurah Sanjaya-Putra, Soetjiningsih Budiarsa, Yati Soenarto
BACKGROUND: Diarrhea is a major public health concern throughout the world because the prevalence of morbidity of diarrhea has not changed significantly in the past decade. It remains the third leading cause of death among children less than 5 years of age. Recent surveillance studies have shown that rotavirus is a significant cause of pediatric hospitalization and death due to diarrhea. Indonesia has limited data on risk factors, disease burden, and deaths in children due to rotavirus diarrhea...
2014: BMC Gastroenterology
Simona Ciccarelli, Ilaria Stolfi, Giuseppe Caramia
Acute gastroenteritis, characterized by the onset of diarrhea with or without vomiting, continues to be a major cause of morbidity and mortality in children in mostly resource-constrained nations. Although generally a mild and self-limiting disease, gastroenteritis is one of the most common causes of hospitalization and is associated with a substantial disease burden. Worldwide, up to 40% of children aged less than 5 years with diarrhea are hospitalized with rotavirus. Also, some microorganisms have been found predominantly in resource-constrained nations, including Shigella spp, Vibrio cholerae, and the protozoan infections...
October 29, 2013: Infection and Drug Resistance
Wen-Chieh Yang, Lu-Lu Zhao, Yu-Cheng Li, Chi-Hua Chen, Yu-Jun Chang, Yun-Ching Fu, Han-Ping Wu
BACKGROUND: Severe dehydration is generally believed to be a cause of significant hyperbilirubinemia in newborn babies. This study aimed to analyze the weight loss of healthy term newborn infants at 24, 48 and 72 hours after birth to predict significant hyperbilirubinemia at 72 hours. METHODS: From January 2007 to December 2008, we conducted this retrospective chart review by measuring total bilirubin (transcutaneous and serum) in 343 healthy, term newborns with a birth body weight of more than 2500 g...
2013: BMC Pediatrics
Christa L Fischer Walker, Olivier Fontaine, Robert E Black
Diarrhea morbidity and mortality remain important child health problems in low- and middle-income countries. The treatment of diarrhea and accurate measurement of treatment coverage are critical if child mortality is going to continue to decline. In this review, we examine diarrhea treatment coverage indicators collected in two large-scale community-based household surveys--the Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS). Current surveys do not distinguish between children with mild diarrhea episodes and those at risk for dehydration...
2013: PLoS Medicine
Caitlin A Cooper, Lydia C Garas Klobas, Elizabeth A Maga, James D Murray
Childhood diarrhea is a significant problem in many developing countries and E. coli is a main causative agent of diarrhea in young children. Lysozyme is an antimicrobial protein highly expressed in human milk, but not ruminant milk, and is thought to help protect breastfeeding children against diarrheal diseases. We hypothesized that consumption of milk from transgenic goats which produce human lysozyme (hLZ-milk) in their milk would accelerate recovery from bacterial-induced diarrhea. Young pigs were used as a model for children and infected with enterotoxigenic E...
2013: PloS One
I Bentama, I Soussi, Z Ghanimi, S Riane, H Tligui, A Mdaghri Alaoui, A Thimou Izgua
The goal of work is to establish a clinical descriptive analysis of the epidemic of nosocomial rotavirus occurred in the Neonatal Unit of the Hospital's Child Rabat for a winter period. We systematically collected all the patients of the service right from the first case of rotavirus nosocomial infection. Patients with a stay of less than 48 hours of hospitalization were excluded. We have established operating sheets for all positive cases, with the term, birth weight, postnatal age and weight during the sampling, clinical symptoms, treatment, and the evolution...
November 2012: Revue Médicale de Bruxelles
Christopher S Yilgwan, S N Okolo
BACKGROUND: Diarrhea is widely recognized as a major cause of childhood morbidity and mortality in many developing countries, particularly in sub-Saharan Africa. According to World Health Organization (WHO) report in the African region, diarrheal diseases are still leading causes of mortality and morbidity in children under five years of age. This same report indicates that each child in the said region has five episodes of diarrhea per year and that 800,000 die each year from diarrhea and dehydration...
October 2012: Annals of African Medicine
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