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https://www.readbyqxmd.com/read/28805345/laparoscopic-sleeve-gastrectomy-improves-renal-transplant-candidacy-and-post-transplant-outcomes-in-morbidly-obese-patients
#1
Y Kim, A D Jung, V K Dhar, J S Tadros, D P Schauer, E P Smith, D J Hanseman, M C Cuffy, R R Alloway, A R Shields, S A Shah, E S Woodle, T S Diwan
Morbid obesity is a barrier to KT due to inferior outcomes, including higher rates of new-onset diabetes after transplantation (NODAT), delayed graft function (DGF), and graft failure. LSG increases transplant eligibility by reducing body mass index (BMI) in KT candidates, but the effect of surgical weight loss on post-transplant outcomes is unknown. Reviewing single-center medical records, we identified all patients who underwent LSG prior to KT from 2011-2016 (n=20). Post-LSG kidney recipients were compared with similar-BMI recipients who did not undergo LSG, using 2:1 direct matching for patient factors...
August 14, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28799403/combined-4-component-and-relativistic-pseudopotential-study-of-tho-for-the-electron-electric-dipole-moment-search
#2
L V Skripnikov
A precise theoretical study of the electronic structure of heavy atom diatomic molecules is of key importance to interpret the experiments in the search for violation of time-reversal (T) and spatial-parity (P) symmetries of fundamental interactions in terms of the electron electric dipole moment, eEDM, and dimensionless constant, kT,P, characterizing the strength of the T,P-odd pseudoscalar-scalar electron-nucleus neutral current interaction. The ACME collaboration has recently improved limits on these quantities using a beam of ThO molecules in the electronic H(3)Δ1 state [J...
December 7, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28795535/update-on-postdialysis-rebound-by-a-new-technology-in-hemodialysis
#3
Alicia García Testal, David Hervás Marín, Rafael García Maset, Pilar Royo Maicas, Inmaculada Soledad Rico Salvador, Pau Olagüe Díaz, Jose Enrique Fernández Najera, Eduardo Torregrosa De Juan, Caterina Benedito Carrera
After dialysis ends, urea continued movement causes rebound postdialysis, with values at about 20%. New techniques have been incorporated into hemodialysis, but their relationship with rebound has not yet been studied. This study aimed to quantify urea rebound at 30-min postdialysis during sessions using polysulfone filters and high-flow versus online hemodiafiltration, and to define its correlation with body composition measured by bioimpedance by a cross-sectional study with 69 patients (December 2015 to January 2016)...
August 9, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28769539/elevation-of-platelet-and-monocyte-activity-markers-of-atherosclerosis-in-haemodialysis-patients-compared-to-peritoneal-dialysis-patients
#4
Ksenija Stach, Susanne Karb, Ibrahim Akin, Martin Borggrefe, Bernhard Krämer, Thorsten Kälsch, Anna-Isabelle Kälsch
PURPOSE: The predominant cause of mortality in dialysis patients are cardiovascular events. Platelet and monocyte activity markers play an important role in cardiovascular mortality and were assessed and related to dialysis quality criteria in haemodialysis (HD) and peritoneal dialysis (PD) patients. METHODS: For this prospective comparative study, HD patients (n = 41) and PD patients (n = 10) were included. In whole blood samples, surface expression of CD62P and CD40L on platelets, tissue factor binding on monocytes, and platelet-monocyte aggregates were measured by flow cytometry...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28768782/anterior-cruciate-ligament-reconstruction-in-skeletally-immature-patients-a-systematic-review
#5
U G Longo, M Ciuffreda, C Casciaro, N Mannering, V Candela, G Salvatore, V Denaro
AIMS: Different methods of anterior cruciate ligament (ACL) reconstruction have been described for skeletally immature patients before closure of the growth plates. However, the outcome and complications following this treatment remain unclear. The aim of this systematic review was to analyse the outcome and complications of different techniques which may be used for reconstruction of the ACL in these patients. MATERIALS AND METHODS: We performed a systematic review of the literature according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
August 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28768540/in-vivo-and-in-vitro-performance-of-a-china-made-hemodialysis-machine-a-multi-center-prospective-controlled-study
#6
Yong Wang, Xiang-Mei Chen, Guang-Yan Cai, Wen-Ge Li, Ai-Hua Zhang, Li-Rong Hao, Ming Shi, Rong Wang, Hong-Li Jiang, Hui-Min Luo, Dong Zhang, Xue-Feng Sun
OBJECTIVE: To evaluate the in vivo and in vitro performance of a China-made dialysis machine (SWS-4000). METHODS: This was a multi-center prospective controlled study consisting of both long-term in vitro evaluations and cross-over in vivo tests in 132 patients. The China-made SWS-4000 dialysis machine was compared with a German-made dialysis machine (Fresenius 4008) with regard to Kt/V values, URR values, and dialysis-related adverse reactions in patients on maintenance hemodialysis, as well as the ultrafiltration rate, the concentration of electrolytes in the proportioned dialysate, the rate of heparin injection, the flow rate of the blood pump, and the rate of malfunction...
August 2, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28766494/resting-energy-expenditure-a-valuable-predictor-for-kt-vurea-in-peritoneal-dialysis-patients%C3%A2
#7
Tian Xu, Jingyuan Xie, Weiming Wang, Hong Ren, Nan Chen
OBJECTIVE: The objective of this study was to identify an effective method for predicting small-molecule solute removal at the commencement of or before peritoneal dialysis (PD). METHODS: The PD patients with a dialysis delivery of 8 L/d and a residual kidney function (RKF) ≤ 5 mL/min were enrolled in the study. Fat-free lean body mass (FFM) and resting energy expenditure (REE) were measured using bioelectrical impedance (BIA). A receiver operating characteristic (ROC) curve was drawn to determine the threshold value for REE...
September 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28748874/variables-affecting-darbepoetin-resistance-index-in-hemodialysis-patients
#8
Fayez Hejaili, Ehtsham Hafeez, Burhan Bhutto, Lulwa Al Turki, Abdul Kareem Alsuwida, Hammad Raza, Abdulla Al-Sayyari
Erythropoietin resistance index calculation has been used as a tool to evaluate anemia response to erythropoietin therapy. Very little has been reported in its use when using darbepoetin and factors influencing in Arab patients. Darbepoetin resistance index (DRI) was calculated in all our patients using darbepoetin. This was correlated to demographic, clinical, and laboratory parameters. Of the 250 patients, 40.4% were diabetic, 71.1% on hemodialysis, and 28.6% on hemodiafiltration), 23.9% with PermCaths (PC), and 76...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28729382/recommended-clinical-trial-end-points-for-dialysis-catheters
#9
Michael Allon, Deborah J Brouwer-Maier, Kenneth Abreo, Kevin M Baskin, Kay Bregel, Deepa H Chand, Andrea M Easom, Leonard Mermel, Michele H Mokrzycki, Priti R Patel, Prabir Roy-Chaudhury, Surendra Shenoy, Rudolph P Valentini, Haimanot Wasse
Central venous catheters are used frequently in patients on hemodialysis as a bridge to a permanent vascular access. They are prone to frequent complications, including catheter-related bloodstream infection, catheter dysfunction, and central vein obstruction. There is a compelling need to develop new drugs or devices to prevent central venous catheter complications. We convened a multidisciplinary panel of experts to propose standardized definitions of catheter end points to guide the design of future clinical trials seeking approval from the Food and Drug Administration...
July 20, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28725318/detection-of-apolipoprotein-e-gene-polymorphism-and-blood-lipid-level-in-hemodialysis-patients
#10
Yuxin Wang, Ning Wang, Yuanshan Lu, Qing Yu, Lina Zhou, Qinjun Xu
BACKGROUND: The aim was to investigate the clinical characteristics of lipid metabolism and the effect of apolipoprotein E (ApoE) gene polymorphism on lipid metabolism in hemodialysis patients. METHODS: The serum levels of total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDLC), low-density lipoprotein cholesterol (LDLC), ApoA1, ApoB, ApoE and lipoprotein Lp(a) were detected by polymerase chain reaction-restriction fragment length (PCR-RFLP)...
August 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28711061/relation-between-cidnp-formed-upon-geminate-and-bulk-recombination-of-radical-pairs
#11
Denis V Sosnovsky, Olga B Morozova, Alexandra V Yurkovskaya, Konstantin L Ivanov
A theoretical approach to time-resolved Chemically Induced Dynamic Nuclear Polarization (CIDNP) is proposed, which allows one to obtain the general relation between polarization formed upon recombination of geminate spin-correlated radical pairs, the so-called G-pairs, and upon recombination of radical pairs formed by encounters of free radicals in solution, the so-called F-pairs. This relation is described by a universal parameter denoted as γ. In this work, the γ value is computed for the arbitrary spin multiplicity, singlet or triplet, of the precursor of the G-pairs as well as for arbitrary recombination rate constants of radical pairs in singlet and triplet states, kS and kT, respectively...
July 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28711056/communication-theoretical-study-of-hff-cation-to-search-for-the-t-p-odd-interactions
#12
L V Skripnikov
The combined all-electron and two-step approach is applied to calculate the molecular parameters which are required to interpret the ongoing experiment to search for the effects of manifestation of the T,P-odd fundamental interactions in the HfF(+) cation by Loh et al. [Science 342, 1220 (2013)] and Ni et al. [J. Mol. Spectrosc. 300, 12 (2014)]. The effective electric field that is required to interpret the experiment in terms of the electron electric dipole moment is found to be 22.5 GV/cm. In the work of Pospelov and Ritz [Phys...
July 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28700186/-the-treatment-of-aki-in-nephrology-hospitalization-the-sle-hdf-15-litres-in-10-hours
#13
REVIEW
Marcello Napoli, Maria Luisa Lefons, Giovanni Sandri, Efisio Sozzo, Carmela Ambrosino
The AKI in intensive care has been widely treated by international and national guidelines. The treatment of AKI in patients not requiring admission in Intensive Care Unit, but often hospitalized in Nephrology Unit, it is showed of less relevance. For over 5 years we have used for the treatment of AKI of patients admitted in Nephrology Unit an intermittent slow technique, implemented in approximately 600 patients with AKI for a total of about 3000 treatments. In this study we report the clinical results obtained in 100 consecutive patients referred to our Nephrology Unit from 1st January 2014...
June 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28675885/high-performance-membrane-dialyzers-and-mortality-in-hemodialysis-patients-a-2-year-cohort-study-from-the-annual-survey-of-the-japanese-renal-data-registry
#14
Masanori Abe, Takayuki Hamano, Atsushi Wada, Shigeru Nakai, Ikuto Masakane
BACKGROUND: Little information is available regarding the type of dialyzer which results in good prognosis. This study is aimed at investigating the association between 7 types of dialyzers and 2-year mortality. METHODS: We conducted a cohort study using data from a nationwide registry of the Japanese Society for Dialysis Therapy. Subjects were 136,676 patients on maintenance hemodialysis (HD) between 2009 and 2011 who underwent maintenance HD for at least 2 years and were treated with one of the following 7 types of high-performance membrane dialyzers: cellulose triacetate (CTA), ethylene vinyl alcohol (EVAL), polyacrylonitrile (PAN), polyester polymer alloy (PEPA), polyethersulfone (PES), polymethylmethacrylate (PMMA), and polysulfone (PS)...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28656379/physiology-and-pathophysiology-of-the-plasminogen-system-in-the-kidney
#15
REVIEW
Per Svenningsen, Gitte Rye Hinrichs, Rikke Zachar, Rikke Ydegaard, Boye L Jensen
The plasminogen system is important for fibrinolysis in addition to tissue remodeling and inflammation with significance for kidney disease. The system consists of the circulating zymogen plasminogen (Plg) and the tissue- and urokinase-type plasminogen activators, tPA and uPA, expressed in the glomeruli, endothelium and tubular epithelium, respectively, and the inhibitors α2-antiplasmin and plasminogen activator inhibitor-type1, PAI-1. Plasminogen is activated by surface receptors, some with renal expression: urokinase-type plasminogen activator receptor (uPAR), plasminogen receptor KT (Plg-RKT), and tPA, most evident in the endothelium...
June 27, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/28652800/nutritional-status-among-peritoneal-dialysis-patients-after-oral-supplement-with-once-dialyze-formula
#16
Bancha Satirapoj, Pokkrong Limwannata, Chadarat Kleebchaiyaphum, Janjira Prapakorn, Ussanee Yatinan, Samitti Chotsriluecha, Ouppatham Supasyndh
BACKGROUND: Malnutrition is an important problem in patients treated with long-term dialysis, and most dialysis patients have lower dietary energy and protein intake. This study was undertaken to examine whether orally administered Otsuka Nutrition Pharmaceutical (ONCE) dialyze formula (ODF) supplement would improve energy intake without mineral and electrolyte disturbances in patients with continuous ambulatory peritoneal dialysis (CAPD). METHODS: The effects of ODF supplementation on nutrition markers including serum albumin and prealbumin concentrations and inflammatory stress in patients with chronic CAPD were evaluated...
2017: International Journal of Nephrology and Renovascular Disease
https://www.readbyqxmd.com/read/28648652/dialysis-related-parameters-influence-remodeling-in-the-venous-part-of-the-native-arteriovenous-fistula
#17
Tomasz Gołębiowski, Mariusz Kusztal, Krzysztof Letachowicz, Hanna Augustyniak-Bartosik, Maciej Szymczak, Magdalena Krajewska, Wojciech Marcinkowski, Wacław Weyde, Marian Klinger
AIM: The aim of this study was to evaluate the association of hemodynamic parameters related to hemodialysis and antropometric parameters of patients with changes in the venous part of the arteriovenous fistula (AVF) at points of needling. MATERIAL AND METHODS: 242 HD patients (60.3% men), with median age 65 [IQR 56-75] years, on HD treatment for a median of 49 [IQR 20-88] months with functioning fistula were recruited to the study. The history of vascular access, comorbidity, antropometric (BMI, BSA, body composition) and dialysis-related parameters were analyzed...
June 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28586767/quantification-and-dosing-of-renal-replacement-therapy-in-acute-kidney-injury-a-reappraisal
#18
William R Clark, Martine Leblanc, Zaccaria Ricci, Claudio Ronco
BACKGROUND/AIMS: Delivered dialysis therapy is routinely measured in the management of patients with end-stage renal disease; yet, the quantification of renal replacement prescription and delivery in acute kidney injury (AKI) is less established. While continuous renal replacement therapy (CRRT) is widely understood to have greater solute clearance capabilities relative to intermittent therapies, neither urea nor any other solute is specifically employed for CRRT dose assessments in clinical practice at present...
2017: Blood Purification
https://www.readbyqxmd.com/read/28584226/comparison-of-3-times-a-week-4-and-5-hour-in-center-hemodialysis-sessions-with-use-of-continuous-non-invasive-hemodynamic-monitoring
#19
Łukasz Czyżewski, Janusz Wyzgał, Janusz Sierdziński, Emilia Czyżewska, Jacek Smereka, Łukasz Szarpak
BACKGROUND Very aggressive ultrafiltration rate (lasting 3.5-4 h) may result in inadequate hemodialysis (HD). Our aim was to characterize HD-induced cardiovascular adaptation and its links to fluid removal during 4- vs. 5-h HD sessions. MATERIAL AND METHODS The study involved 50 HD patients. A Cardioscreen device (Messtechnik, Ilmenau, Germany) was used to perform non-invasive hemodynamic measurements during mid-week HD sessions. Body fluids and nutritional status were assessed with a Body Composition Monitor (Fresenius Medical Care)...
June 6, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28581770/collimated-propagation-of-fast-electron-beams-accelerated-by-high-contrast-laser-pulses-in-highly-resistive-shocked-carbon
#20
X Vaisseau, A Morace, M Touati, M Nakatsutsumi, S D Baton, S Hulin, Ph Nicolaï, R Nuter, D Batani, F N Beg, J Breil, R Fedosejevs, J-L Feugeas, P Forestier-Colleoni, C Fourment, S Fujioka, L Giuffrida, S Kerr, H S McLean, H Sawada, V T Tikhonchuk, J J Santos
Collimated transport of ultrahigh intensity electron current was observed in cold and in laser-shocked vitreous carbon, in agreement with simulation predictions. The fast electron beams were created by coupling high-intensity and high-contrast laser pulses onto copper-coated cones drilled into the carbon samples. The guiding mechanism-observed only for times before the shock breakout at the inner cone tip-is due to self-generated resistive magnetic fields of ∼0.5-1  kT arising from the intense currents of fast electrons in vitreous carbon, by virtue of its specific high resistivity over the range of explored background temperatures...
May 19, 2017: Physical Review Letters
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