keyword
MENU ▼
Read by QxMD icon Read
search

"Glycated albumin"

keyword
https://www.readbyqxmd.com/read/29279271/challenges-in-diagnosing-and-monitoring-diabetes-in-patients-with-chronic-liver-diseases
#1
REVIEW
Telma E Silva, Marcelo F Ronsoni, Leonardo L Schiavon
The prevalence and mortality of diabetes mellitus and liver disease have risen in recent years. The liver plays an important role in glucose homeostasis, and various chronic liver diseases have a negative effect on glucose metabolism with the consequent emergence of diabetes. Some aspects related to chronic liver disease can affect diagnostic tools and the monitoring of diabetes and other glucose metabolism disorders, and clinicians must be aware of these limitations in their daily practice. In cirrhotic patients, fasting glucose may be normal in up until 23% of diabetes cases, and glycated hemoglobin provides falsely low results, especially in advanced cirrhosis...
December 20, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29275415/comparison-of-glycemic-markers-in-chronic-hemodialysis-using-continuous-glucose-monitoring
#2
Maria Divani, Panagiotis I Georgianos, Triantafyllos Didangelos, Fotios Iliadis, Areti Makedou, Apostolos Hatzitolios, Vassilios Liakopoulos, Dimitrios M Grekas
BACKGROUND: Glycated hemoglobin A1c (HbA1c) among diabetic hemodialysis patients continues to be the standard of care, although its limitations are well recognized. This study evaluated glycated albumin (GA) and glycated serum protein (GSP) as alternatives to HbA1c in detecting glycemic control among diabetic hemodialysis patients using continuous-glucose-monitoring (CGM)-derived glucose as reference standard. METHODS: A CGM system (iPRO) was applied for 7 days in 37 diabetic hemodialysis patients to determine glycemic control...
December 22, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/29275401/glycemic-control-assessment-in-the-dialysis-patient-is-glycated-albumin-the-answer
#3
Mark E Molitch
No abstract text is available yet for this article.
December 22, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/29238514/diagnostic-value-of-glycemic-markers-hba1c-1-5-anhydroglucitol-and-glycated-albumin-in-evaluating-gestational-diabetes-mellitus
#4
Baris Saglam, Sezer Uysal, Sadik Sozdinler, Omer Erbil Dogan, Banu Onvural
Background: The oral glucose tolerance test (OGTT) is the current established method performed worldwide to diagnose gestational diabetes mellitus (GDM). The purpose of this study was to assess the utility of the use of long- and short-term markers of glycemic status. Methods: The study group was composed of 80 pregnant women, 40 with GDM and 40 with normal glucose tolerance. GDM was diagnosed with the American Diabetes Association criteria. Glycemic markers were measured in the OGTT blood samples of women at 24-28 weeks of gestation...
December 2017: Therapeutic Advances in Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29225250/importance-of-the-average-glucose-level-and-estimated-glycated-hemoglobin-in-a-diabetic-patient-with-hereditary-hemolytic-anemia-and-liver-cirrhosis
#5
Rieko Nakatani, Takashi Murata, Takeshi Usui, Koki Moriyoshi, Toshiki Komeda, Yuichi Masuda, Maiko Kakita-Kobayashi, Tetsuya Tagami, Shinsaku Imashuku, Shigeo Kono, Kazunori Yamada, Akira Shimatsu
Glycated hemoglobin (HbA1c) is a widely used marker of glycemic control but can be affected by hemolytic anemia. Glycated albumin (GA) is also affected in patients with liver cirrhosis. We herein report the assessment of glycemic control in a 41-year-old man with dehydrated hereditary stomatocytosis and a PIEZO1 gene mutation complicated by diabetes mellitus and liver cirrhosis due to hemochromatosis. The estimated HbA1c calculated from the average glucose level obtained by continuous glucose monitoring or by self-monitoring of blood glucose was useful for evaluating the glycemic control in this patient, as HbA1c and GA were unreliable due to the coexisting conditions...
December 8, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29170429/genome-wide-meta-analysis-in-japanese-populations-identifies-novel-variants-at-the-tmc6-tmc8-and-six3-six2-loci-associated-with-hba1c
#6
Tsuyoshi Hachiya, Shohei Komaki, Yutaka Hasegawa, Hideki Ohmomo, Kozo Tanno, Atsushi Hozawa, Gen Tamiya, Masayuki Yamamoto, Kuniaki Ogasawara, Motoyuki Nakamura, Jiro Hitomi, Yasushi Ishigaki, Makoto Sasaki, Atsushi Shimizu
Glycated haemoglobin (HbA1c) is widely used as a biomarker for the diagnosis of diabetes, for population-level screening, and for monitoring the glycaemic status during medical treatment. Although the heritability of HbA1c has been estimated at ~55-75%, a much smaller proportion of phenotypic variance is explained by the HbA1c-associated variants identified so far. To search for novel loci influencing the HbA1c levels, we conducted a genome-wide meta-analysis of 2 non-diabetic Japanese populations (n = 7,704 subjects in total)...
November 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29147074/increased-levels-of-srage-in-diabetic-ckd-g5d-patients-a-potential-protective-mechanism-against-age-related-upregulation-of-fibroblast-growth-factor-23-and-inflammation
#7
Elena Dozio, Valentina Corradi, Elena Vianello, Elisa Scalzotto, Massimo de Cal, Massimiliano Marco Corsi Romanelli, Claudio Ronco
Advanced glycation end products (AGEs) may induce cardiac remodeling in kidney disease by promoting fibroblast growth factor 23 (FGF-23) expression. Since AGEs are increased in diabetes mellitus (DM), our first aim was to evaluate the existence of any potential association between AGEs, FGF-23, inflammation, and increased cardiovascular risk in DM patients on dialysis (CKD-G5D). Secondarily, we explored the potential role of the soluble receptor for AGEs (sRAGE) as a marker of heart failure. Levels of glycated albumin (GA), sRAGE, c-terminal FGF-23 (cFGF-23), brain natriuretic peptide (BNP), and inflammatory mediators were compared between DM and non-DM CKD-G5D patients...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/29142432/inhibition-of-glycation-induced-cytotoxicity-protein-glycation-and-activity-of-proteolytic-enzymes-by-extract-from-perovskia-atriplicifolia-roots
#8
Mehran Miroliaei, Akram Aminjafari, Sylwester Ślusarczyk, Izabela Nawrot-Hadzik, Mehdi Rahimmalek, Adam Matkowski
Background: Protein glycation and glycotoxicity belong to the main oxidative-stress related complications in diabetes. Perovskia species are used in Asian folk medicine as antidiabetic herbs. Objective: The aim of this study was to verify the ability of the methanolic extract from Perovskia atriplicifolia Benth. roots to diminish glycation of albumin and to prevent cell damage in vitro. Furthermore, we tested the extract for in vitro antioxidant activity and inhibition of elastase and collagenase...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29133805/xanthine-oxidoreductase-activity-is-associated-with-serum-uric-acid-and-glycemic-control-in-hemodialysis-patients
#9
Ayumi Nakatani, Shinya Nakatani, Eiji Ishimura, Takayo Murase, Takashi Nakamura, Mari Sakura, Yu Tateishi, Akihiro Tsuda, Masafumi Kurajoh, Katsuhito Mori, Masanori Emoto, Masaaki Inaba
Xanthine oxidoreductase activity (XOR-a) plays an important role as a pivotal source of reactive oxygen species. In the present study, we investigated factors associated with plasma XOR-a in 163 hemodialysis patients (age 67.3 ± 10.9 years; 89 males and 74 females), using a newly established, highly-sensitive assay based on [(13)C2,(15)N2] xanthine and liquid chromatography/triple quadrupole mass spectrometry. Plasma glucose and serum uric acid levels correlated significantly and positively with plasma XOR-a...
November 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29106815/high-dose-glucocorticoids-treatment-does-not-induce-severe-hyperglycemia-in-young-patients-with-autoimmune-diseases-by-cgms
#10
Ying Zhou, Yan Zhao, Tao Yuan, Nan Jiang, Yingyue Dong, Yunjiao Yang, Li Wang, Jiuliang Zhao, Le Min, Weigang Zhao
INTRODUCTION: High-dose glucocorticoids (HDG) are used in the treatment of autoimmune diseases. Glucocorticoids-induced hyperglycemia (GIH) is often described in elderly patients. In young patients with autoimmune diseases, however, the risk for GIH has not been well characterized. METHODS: Twenty-four inpatients (median age 32 years (interquatile range 25-42)) with exacerbations of autoimmune diseases, receiving 1-2mg/kg/day prednisone or equivalent methylprednisone, were recruited...
November 6, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29104592/comparative-agreement-analysis-of-differences-in-1-5-anhydroglucitol-glycated-albumin-and-glycated-hemoglobin-a1c-levels-between-fasting-and-postprandial-states-in-steamed-bread-meal-test
#11
Hang Su, Yufei Wang, Xiaojing Ma, Xingxing He, Lingwen Ying, Junling Tang, Lu Dong, Yuqian Bao, Jian Zhou, Weiping Jia
Background: Our previous study indicated that serum 1,5-anhydroglucitol (1,5-AG) levels slightly increased after a glucose load; therefore, this study was conducted to explore short-term changes in 1,5-AG levels after a steamed bread meal test (SBMT) and compare the agreement of 1,5-AG, glycated albumin (GA), and glycated hemoglobin A1c (HbA1c) levels between fasting and postprandial states after an SBMT. Methods: 104 participants were recruited and underwent a 100 g SBMT...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29061312/an-additional-measurement-of-glycated-albumin-can-help-prevent-missed-diagnosis-of-diabetes-in-chinese-population
#12
Xingxing He, Lingwen Ying, Xiaojing Ma, Yun Shen, Hang Su, Jiahui Peng, Yufei Wang, Yuqian Bao, Jian Zhou, Weiping Jia
BACKGROUND: In subjects who present a first fasting plasma glucose (FPG1) ≥7.0mmol/l without classic symptoms of diabetes, diagnosis of diabetes will likely be missed without an additional oral glucose tolerance test (OGTT) in the Chinese population. Recent studies have shown that glycated albumin (GA) has advantages in reflecting postprandial hyperglycemia. Therefore, the present study evaluated whether additional measurement of GA could reduce the rate of missed diagnosis of diabetes...
October 20, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29057494/a-decrease-in-serum-1-5-anhydroglucitol-levels-is-associated-with-the-presence-of-a-first-degree-family-history-of-diabetes-in-a-chinese-population-with-normal-glucose-tolerance
#13
X Hu, X He, X Ma, H Su, L Ying, J Peng, Y Wang, Y Bao, J Zhou, W Jia
AIM: This study aimed to investigate alterations in HbA1c , glycated albumin (GA) and 1,5-anhydroglucitol (1,5-AG) in Chinese first-degree relatives of individuals with diabetes (FDR) in pursuit of an index for early screening of glucose metabolism disturbance. METHODS: A total of 467 participants (age range: 20-78 years) with normal weight and normal glucose tolerance, as determined by a 75-g oral glucose tolerance test, were enrolled. HbA1c was measured using high-pressure liquid chromatography...
October 23, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29055090/performance-of-nontraditional-hyperglycemia-biomarkers-by-chronic-kidney-disease-status-in-older-adults-with-diabetes-results-from-the-atherosclerosis-risk-in-communities-study
#14
Molly Jung, Bethany Warren, Morgan Grams, Yuenting Diana Kwong, Tariq Shafi, Josef Coresh, Casey M Rebholz, Elizabeth Selvin
BACKGROUND: In persons with chronic kidney disease (CKD), hemoglobin A1c (HbA1c) may be a problematic measure of glycemic control. Glycated albumin and fructosamine have been proposed as better markers of hyperglycemia in CKD. We investigated associations of HbA1c, glycated albumin, and fructosamine with fasting glucose by CKD categories. METHODS: Cross-sectional analysis of 1,665 Atherosclerosis Risk in Communities Study participants with diagnosed diabetes aged 65 years or older...
October 20, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/29052590/reversing-the-tide-diagnosis-and-prevention-of-t2dm-in-populations-of-african-descent
#15
REVIEW
Jean N Utumatwishima, Stephanie T Chung, Amy R Bentley, Margaret Udahogora, Anne E Sumner
Populations of African descent are at the forefront of the worldwide epidemic of type 2 diabetes mellitus (T2DM). The burden of T2DM is amplified by diagnosis after preventable complications of the disease have occurred. Earlier detection would result in a reduction in undiagnosed T2DM, more accurate statistics, more informed resource allocation and better health. An underappreciated factor contributing to undiagnosed T2DM in populations of African descent is that screening tests for hyperglycaemia, specifically, fasting plasma glucose and HbA1c, perform sub-optimally in these populations...
January 2018: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/29051218/stress-hyperglycemia-and-prognosis-of-minor-ischemic-stroke-and-transient-ischemic-attack-the-chance-study-clopidogrel-in-high-risk-patients-with-acute-nondisabling-cerebrovascular-events
#16
RANDOMIZED CONTROLLED TRIAL
Yuesong Pan, Xueli Cai, Jing Jing, Xia Meng, Hao Li, Yongjun Wang, Xingquan Zhao, Liping Liu, David Wang, S Claiborne Johnston, Tiemin Wei, Yilong Wang
BACKGROUND AND PURPOSE: We aimed to determine the association between stress hyperglycemia and risk of new stroke in patients with a minor ischemic stroke or transient ischemic attack. METHODS: A subgroup of 3026 consecutive patients from 73 prespecified sites of the CHANCE trial (Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events) were analyzed. Stress hyperglycemia was measured by glucose/glycated albumin (GA) ratio. Glucose/GA ratio was calculated by fasting plasma glucose divided by GA and categorized into 4 even groups according to the quartiles...
November 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29044634/rituximab-for-the-treatment-of-type-b-insulin-resistance-syndrome-a-case-report-and-review-of-the-literature
#17
Ken Iseri, Masayuki Iyoda, Yasuto Shikida, Takako Inokuchi, Tomoki Morikawa, Noriko Hara, Tsutomu Hirano, Takanori Shibata
BACKGROUND: Type B insulin resistance syndrome is a rare disease characterized by refractory transient hyperglycaemia and severe insulin resistance associated with circulating anti-insulin receptor antibodies. A standardized treatment regimen for type B insulin resistance syndrome has yet to be established. CASE REPORT: We report the case of a 64-year-old man undergoing haemodialysis for antineutrophil cytoplasmic antibody-associated vasculitis and diabetic nephropathy, who developed rapid onset of hyperglycaemia (glycated albumin 52...
October 16, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29031829/gain-of-function-variants-in-nlrp1-protect-against-the-development-of-diabetic-kidney-disease-nlrp1-inflammasome-role-in-metabolic-stress-sensing
#18
Jaine L S Soares, Fernanda Pereira Fernandes, Thiago Andrade Patente, Maria B Monteiro, Maria C Parisi, Daniel Giannella-Neto, Maria L Corrêa-Giannella, Alessandra Pontillo
Although inflammasome plays a well-known role in animal models of renal injury, limited studies in humans are available, and its participation in diabetic kidney disease (DKD) remains unknown. Aim of this study was to elucidate the contribution of inflammasome genetics in the development of DKD in type-1 diabetes (T1D). The association of functional variants in inflammasome genes with DKD was assessed by multivariate analysis in a retrospective and in a prospective cohort. NLRP1 rs2670660 and rs11651270 polymorphisms were significantly associated with a decrease risk to develop DKD (padj<0...
October 12, 2017: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/29022053/glycated-albumin-ga-and-inflammation-role-of-ga-as-a-potential-marker-of-inflammation
#19
REVIEW
H Vernon Roohk, Asad R Zaidi, Dimple Patel
AIMS: Abnormal levels of glycated albumin (GA) are associated with the onset of both diabetes and inflammation. Although inflammation has long been associated with diabetes, this article aims to explore the underlying mechanisms of this relationship as it pertains to the role of GA. METHODS: We have reviewed 52 research articles since the year 2000. Common search terms used were "(inflammatory mediator) and GA" or "inflammation and GA". The findings have been organized according to diabetic complications with respect to the interactions of GA and inflammatory mediators...
January 2018: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/29018354/n-acetylcysteine-counteracts-adipose-tissue-macrophage-infiltration-and-insulin-resistance-elicited-by-advanced-glycated-albumin-in-healthy-rats
#20
Karolline S da Silva, Paula R Pinto, Nelly T Fabre, Diego J Gomes, Karina Thieme, Ligia S Okuda, Rodrigo T Iborra, Vanessa G Freitas, Maria H M Shimizu, Walcy R Teodoro, Suely K N Marie, Tom Woods, Margaret A Brimble, Russell Pickford, Kerry-Anne Rye, Maristela Okamoto, Sergio Catanozi, Maria L Correa-Giannela, Ubiratan F Machado, Marisa Passarelli
Background: Advanced glycation endproducts elicit inflammation. However, their role in adipocyte macrophage infiltration and in the development of insulin resistance, especially in the absence of the deleterious biochemical pathways that coexist in diabetes mellitus, remains unknown. We investigated the effect of chronic administration of advanced glycated albumin (AGE-albumin) in healthy rats, associated or not with N-acetylcysteine (NAC) treatment, on insulin sensitivity, adipose tissue transcriptome and macrophage infiltration and polarization...
2017: Frontiers in Physiology
keyword
keyword
53174
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"