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https://www.readbyqxmd.com/read/29665492/sex-and-orientation-identity-matter-in-the-substance-use-behaviors-of-sexual-minority-adolescents-in-the-united-states
#1
Theodore L Caputi
BACKGROUND: Health sciences researchers are beginning to understand the differing experiences and health risks among sexual minority subgroups (i.e., those who describe themselves as homosexual/gay/lesbian, bisexual, or unsure/questioning). Such research can promote the allocation of resources to high-risk groups and the development of interventions tailored to their needs. The present study extends this line of research to substance use among adolescents. METHODS: The lifetime and/or past 30-day alcohol, tobacco, cigarette, e-cigarette, marijuana, prescription drug, and illicit drug use of sexual minority and heterosexual adolescents was analyzed using data from the 2015 National Youth Risk Behavior Survey...
March 7, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29660697/relapse-to-smoking-following-release-from-smoke-free-correctional-facilities-in-queensland-australia
#2
Cheneal Puljević, Dominique de Andrade, Ross Coomber, Stuart A Kinner
BACKGROUND: Smoke-free prison policies are increasingly common, but few studies have investigated relapse to smoking after release from prison. This study investigated return to tobacco smoking and correlates of smoking at reduced levels after release among adults recently released from smoke-free prisons in Queensland, Australia. METHODS: A cross-sectional survey of 114 people at parole offices within two months of release from prison was used. The survey measured health, social, and criminological factors related to tobacco smoking...
April 11, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29659506/in-vitro-inhibitory-effects-of-synthetic-cannabinoid-eam-2201-on-cytochrome-p450-and-udp-glucuronosyltransferase-enzyme-activities-in-human-liver-microsomes
#3
Tae Yeon Kong, Soon-Sang Kwon, Jae Chul Cheong, Hee Seung Kim, Jin Young Kim, Hye Suk Lee
EAM-2201, a synthetic cannabinoid, is a potent agonist of the cannabinoid receptors that is widely abused as an illicit recreational drug in combination with other drugs. To evaluate the potential of EAM-2201 as a perpetrator of drug–drug interactions, the inhibitory effects of EAM-2201 on major drug-metabolizing enzymes, cytochrome P450s (CYPs) and uridine 5′-diphospho-glucuronosyltransferases (UGTs) were evaluated in pooled human liver microsomes using liquid chromatography–tandem mass spectrometry (LC-MS/MS)...
April 16, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29656911/healthcare-empowerment-and-hiv-viral-control-mediating-roles-of-adherence-and-retention-in-care
#4
Tracey E Wilson, Emma Sophia Kay, Bulent Turan, Mallory O Johnson, Mirjam-Colette Kempf, Janet M Turan, Mardge H Cohen, Adaora A Adimora, Margaret Pereyra, Elizabeth T Golub, Lakshmi Goparaju, Lynn Murchison, Gina M Wingood, Lisa R Metsch
INTRODUCTION: This study assessed longitudinal relationships between patient healthcare empowerment, engagement in care, and viral control in the Women's Interagency HIV Study, a prospective cohort study of U.S. women living with HIV. METHODS: From April 2014 to March 2016, four consecutive 6-month visits were analyzed among 973 women to assess the impact of Time 1 healthcare empowerment variables (Tolerance for Uncertainty and the state of Informed Collaboration Committed Engagement) on Time 2 reports of ≥95% HIV medication adherence and not missing an HIV primary care appointment since last visit; and on HIV RNA viral control across Times 3 and 4, controlling for illicit drug use, heavy drinking, depression symptoms, age, and income...
April 12, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29652872/medical-management-of-transgender-children-and-adolescents
#5
María Fernanda Castilla-Peón
Transgender or gender nonconforming (GN) persons identify themselves with a gender which is different from that correspondent to their birth sex. The demand for health services by families with transgender children or adolescents tends to increase. The prevalence of GN in children is unknown; however, it has been estimated to be > 1% in adolescents. Transgender persons are at increased risk of depression, suicide, illicit drug abuse, human immunodeficiency virus infection, and non-accidental injury. The most accepted model for the care of transgender persons assumes that these adverse outcomes are the consequence of social margination rather than the GI condition itself...
2018: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/29652552/do-classes-of-polysubstance-use-in-adolescence-differentiate-growth-in-substances-used-in-the-transition-to-young-adulthood
#6
Gabriel J Merrin, Bonnie Leadbeater
BACKGROUND: Past studies have differentiated classes of polysubstance use in adolescence, however, the associations of adolescent polysubstance use classes with longitudinal substance use trajectories from adolescence to young adulthood have not been studied. OBJECTIVE: The current study examined substance use classes during adolescence and longitudinal trajectories of each substance used across the transition to young adulthood. METHOD: Data were collected biennially from 662 youth and followed 10 years across six measurement assessments...
April 13, 2018: Substance Use & Misuse
https://www.readbyqxmd.com/read/29651922/prior-exposure-to-intimate-partner-violence-associated-with-less-hiv-testing-among-young-women
#7
Yukiko Washio, Elizabeth Novack Wright, Annet Davis-Vogel, Jesse Chittams, Claire Anagnostopulos, Linda M Kilby, Anne M Teitelman
Low-income minority women are disproportionately represented among those living with HIV in the United States. They are also at risk for the SAVA (substance abuse, violence, and HIV/AIDS) syndemic issues. Women who have recently given birth are at high risk for substance use and intimate partner violence (IPV), and HIV testing is not routinely administered during the postpartum visit. We explored the relationship between substance use, IPV, and HIV testing among low-income young adult women attending Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), a federally supported nutrition program...
April 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29651200/return-to-illicit-drug-use-post-incarceration-among-formerly-incarcerated-black-americans
#8
Tawandra L Rowell-Cunsolo, Betsy Szeto, Charlotte McDonald, Nabila El-Bassel
Aims: The number of drug dependent individuals incarcerated in the U.S. is exceptionally high, and reportedly 60 percent of incarcerated Black Americans have a substance abuse disorder. The purpose of this study was to identify factors associated with return to illicit drug use post-incarceration. Methods: A cross-sectional study was conducted with 121 formerly incarcerated Black Americans in New York City to examine predictors of return to illicit drug use. Kaplan-Meier curves were generated on the outcome of time-to-drug use for various predictors and compared using the log-rank test...
2018: Drugs: Education, Prevention, and Policy
https://www.readbyqxmd.com/read/29649771/systematic-forensic-toxicological-analysis-by-liquid-chromatography-quadrupole-time-of-flight-mass-spectrometry-in-serum-and-comparison-to-gas-chromatography-mass-spectrometry
#9
Marcel Grapp, Christoph Kaufmann, Frank Streit, Lutz Binder
Comprehensive screening procedures for psychoactive agents in body fluids are an essential task in clinical and forensic toxicology. With the continuous emergence and adaption of new psychoactive substances (NPS) keeping a screening method up to date is challenging. To meet these demands, hyphenated high-resolution mass spectrometry has gained interest as extensive and expandable screening approach. Here we present a comprehensive method for systematic toxicological analysis of serum by liquid chromatography-quadrupole-time-of-flight mass spectrometry (LC-QTOF-MS) with data independent acquisition...
April 3, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29630030/hiv-serostatus-and-having-access-to-a-physician-for-regular-hepatitis-c-virus-care-among-people-who-inject-drugs
#10
Tara Beaulieu, Kanna Hayashi, Michael J Milloy, Ekaterina Nosova, Kora DeBeck, Julio Montaner, Thomas Kerr, Lianping Ti
BACKGROUND: People who inject drugs (PWIDs) and who are living with HIV and hepatitis C virus (HCV) infection are vulnerable to a range of health-related harms, including liver cirrhosis, hepatocellular carcinoma, and death. There is limited evidence describing how HIV serostatus shapes access to a physician for regular HCV care among PWID. SETTING: Data were collected through the Vancouver Injection Drug Users Study (VIDUS), the AIDS Care Cohort to evaluate Exposure to Survival Services (ACCESS), and the At-Risk Youth Study (ARYS), 3 prospective cohorts involving people who use illicit drugs in Vancouver, Canada, between 2005 and 2015...
May 1, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29630016/opioid-detoxification-during-pregnancy-a-systematic-review
#11
Mishka Terplan, Hollis J Laird, Dennis J Hand, Tricia E Wright, Ashish Premkumar, Caitlin E Martin, Marjorie C Meyer, Hendrée E Jones, Elizabeth E Krans
OBJECTIVE: To systematically review maternal and neonatal outcomes associated with opioid detoxification during pregnancy. DATA SOURCES: PubMed, PsycINFO, EMBASE, Cochrane, and ClinicalTrials.gov databases were searched from January 1, 1966, to September 1, 2016. METHODS OF STUDY SELECTION: English-language studies that reported outcomes associated with opioid detoxification among pregnant women with opioid use disorder were included. Nonoriginal research articles (case reports, editorials, reviews) and studies that failed to report outcomes for detoxification participants were excluded...
April 6, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29628175/syndemics-a-theory-in-search-of-data-or-data-in-search-of-a-theory
#12
Alexander C Tsai
The concept of a syndemic was proposed more than two decades ago to explain how large-scale social forces might give rise to co-occurring epidemics that synergistically interact to undermine health in vulnerable populations. This conceptual instrument has the potential to help policymakers and program implementers in their endeavors to improve population health. Accordingly, it has become an increasingly popular heuristic for advocacy, most notably in the field of HIV treatment and prevention. However, most empirical studies purporting to validate the theory of syndemics actually do no such thing...
March 30, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29627821/global-scientific-production-on-illicit-drug-addiction-a-two-decade-analysis
#13
Malahat Khalili, Afarin Rahimi-Movaghar, Behrang Shadloo, Ramin Mojtabai, Karl Mann, Masoumeh Amin-Esmaeili
AIMS: Addiction science has made great progress in the past decades. We conducted a scientometric study in order to quantify the number of publications and the growth rate globally, regionally, and at country levels. METHODS: In October 2015, we searched the Scopus database using the general keywords of addiction or drug-use disorders combined with specific terms regarding 4 groups of illicit drugs - cannabis, opioids, cocaine, and other stimulants or hallucinogens...
April 6, 2018: European Addiction Research
https://www.readbyqxmd.com/read/29627778/bilateral-pneumothorax-surgical-emphysema-and-pneumomediastinum-in-a-young-male-patient-following-mdma-intake
#14
Nonyelum Evangeline Obiechina, Ahrane Jayakumar, Yusra Khan, James Bass
MDMA (3,4-methylenedioxymethamphetamine) or 'Ecstasy' is an illicit drug frequently used by young people at parties and 'raves'. It is readily available in spite of the fact that it is illegal.1 It is perceived by a lot of young people as being 'harmless', but there have been a few high-profile deaths associated with its use.2 Known side effects of MDMA include hyperthermia, rhabdomyolysis, coagulopathy and cardiac arrhythmias.3 Rarer side effects include surgical emphysema and pneumomediastinum, which have been better described with cocaine abuse...
April 7, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29627711/simple-dna-extraction-of-urine-samples-effects-of-storage-temperature-and-storage-time
#15
Huey Hian Ng, Hwee Chen Ang, See Ying Hoe, Mae-Lynn Lim, Hua Eng Tai, Richard Choon Hock Soh, Christopher Kiu-Choong Syn
Urine samples are commonly analysed in cases with suspected illicit drug consumption. In events of alleged sample mishandling, urine sample source identification may be necessary. A simple DNA extraction procedure suitable for STR typing of urine samples was established on the Promega Maxwell® 16 paramagnetic silica bead platform. A small sample volume of 1.7mL was used. Samples were stored at room temperature, 4°C and -20°C for 100days to investigate the influence of storage temperature and time on extracted DNA quantity and success rate of STR typing...
March 29, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29626777/the-source-and-diversion-of-pharmaceutical-drugs-for-non-medical-use-a-systematic-review-and-meta-analysis
#16
REVIEW
Shann Hulme, David Bright, Suzanne Nielsen
BACKGROUND: The non-medical use (NMU) of pharmaceutical drugs is an increasing public health concern. This systematic review consolidates current knowledge about how pharmaceutical drugs are obtained for NMU and the processes and people involved in diversion. METHODS: Peer-reviewed and grey literature databases were searched for empirical studies published between 1996 and 2017 that examined the source or diversion of pharmaceutical opioids, sedatives or stimulants for NMU in countries with reported misuse problems...
March 27, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29626744/opioids-in-oral-fluid-of-spanish-drivers
#17
Francisco Herrera-Gómez, Mercedes García-Mingo, Mónica Colás, Juan Carlos González-Luque, F Javier Álvarez
BACKGROUND: Driving under the influence of certain drugs is not allowed, and roadside drug testing is being considered an important tool for deterring driving under the influence of them. This study aimed to assess the presence and concentration of opioids, as well as their combined use with other drugs (laboratory confirmation after the on-road screening) in Spanish drivers between 2011 and 2016. METHODS: In Spain, mandatory roadside breath alcohol and oral fluid drug testing (screening) are carried out by the Traffic Police using Dräger Alcotest® 6810 device, and Dräger DrugTest® 5000, DrugWipe® , or Alere™ DDS® 2 Mobile Test System...
March 29, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29625621/expanding-harm-reduction-to-include-fentanyl-urine-testing-results-from-a-pilot-in-rural-british-columbia
#18
Silvina C Mema, Chloe Sage, Serge Popoff, Jessica Bridgeman, Deanne Taylor, Trevor Corneil
BACKGROUND: Harm reduction has been at the forefront of the response to the opioid overdose public health emergency in British Columbia (BC). The unprecedented number of opioid overdose deaths in the province calls for an expansion of harm reduction services. The purpose of this study was to determine the acceptability of a fentanyl urine drug test among people who use drugs (PWUD) and explore whether testing introduced any changes in participants' attitudes and behaviors towards their drug use...
April 6, 2018: Harm Reduction Journal
https://www.readbyqxmd.com/read/29625609/lay-responder-naloxone-access-and-good-samaritan-law-compliance-postcard-survey-results-from-20-indiana-counties
#19
Dennis P Watson, Bradley Ray, Lisa Robison, Philip Huynh, Emily Sightes, La Shea Walker, Krista Brucker, Joan Duwve
BACKGROUND: To reduce fatal drug overdoses, two approaches many states have followed is to pass laws expanding naloxone access and Good Samaritan protections for lay persons with high likelihood to respond to an opioid overdose. Most prior research has examined attitudes and knowledge among lay responders in large metropolitan areas who actively use illicit substances. The present study addresses current gaps in knowledge related to this issue through an analysis of data collected from a broader group of lay responders who received naloxone kits from 20 local health departments across Indiana...
April 6, 2018: Harm Reduction Journal
https://www.readbyqxmd.com/read/29623562/decline-in-buprenorphine-naloxone-prescriptions-in-a-state-medicaid-population-following-formulary-conversion-from-suboxone-to-bunavail
#20
Richard Soper, Sireesh Appajosyula, Christina Deximo
INTRODUCTION: A large, statewide, fee-for-service Medicaid plan recently (October 2015) executed a complete switch from sublingual buprenorphine-naloxone [(SLBN), Suboxone® ] to buccal buprenorphine-naloxone [(BBN), Bunavail® ] on its preferred drug formulary. This complete formulary switch provided an opportunity to assess dynamic changes in prescribing patterns, patient/physician acceptance, and indices of potential misuse/diversion. METHODS: For the period January 1, 2015 through December 31, 2016, two datasets were analyzed: prescriptions and associated costs for buprenorphine-naloxone (BN) products and urine toxicology test results for patients in the Medicaid plan...
April 6, 2018: Advances in Therapy
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