keyword
MENU ▼
Read by QxMD icon Read
search

CVE

keyword
https://www.readbyqxmd.com/read/27911398/evaluation-of-bioenergetic-function-in-cerebral-vascular-endothelial-cells
#1
Stephanie L Rellick, Heng Hu, James W Simpkins, Xuefang Ren
The integrity of the blood-brain-barrier (BBB) is critical to prevent brain injury. Cerebral vascular endothelial (CVE) cells are one of the cell types that comprise the BBB; these cells have a very high-energy demand, which requires optimal mitochondrial function. In the case of disease or injury, the mitochondrial function in these cells can be altered, resulting in disease or the opening of the BBB. In this manuscript, we introduce a method to measure mitochondrial function in CVE cells by using whole, intact cells and a bioanalyzer...
November 19, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27895935/systolic-blood-pressure-values-might-further-risk-stratify-the-adverse-outcomes-of-lvh-in-older-patients-with-chronic-kidney-disease
#2
Carlos R Franco Palacios, Pankaj Goyal, Amanda M Thompson, Brent Deschaine
BACKGROUND: LVH is highly prevalent in patients with CKD and is independently associated with subsequent cardiovascular events. We hypothesized that adding systolic blood pressure values to LVH might differentiate different subgroups of patients at higher risk of cardiovascular events (CVE) and other adverse outcomes. METHODS: Retrospective cohort study of 243 patients older than 60 years with stages 1-5 pre-dialysis CKD. LVH was assessed by electrocardiogram or echocardiogram...
2016: Clinical Hypertension
https://www.readbyqxmd.com/read/27871247/cost-effectiveness-of-workplace-wellness-to-prevent-cardiovascular-events-among-u-s-firefighters
#3
P Daniel Patterson, Kenneth J Smith, David Hostler
BACKGROUND: The leading cause of death among firefighters in the United States (U.S.) is cardiovascular events (CVEs) such as sudden cardiac arrest and myocardial infarction. This study compared the cost-effectiveness of three strategies to prevent CVEs among firefighters. METHODS: We used a cost-effectiveness analysis model with published observational and clinical data, and cost quotes for physiologic monitoring devices to determine the cost-effectiveness of three CVE prevention strategies...
November 21, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27782743/the-labile-iron-pool-in-monocytes-reflects-the-activity-of-the-atherosclerotic-process-in-men-with-chronic-cardiovascular-disease
#4
P Riško, J Pláteník, R Buchal, J Potočková, P J Kraml
The study investigates the relationship between the labile iron pool (LIP) in circulating monocytes and markers of iron metabolism, inflammation, oxidative stress, endothelial dysfunction and arterial elasticity in patients with chronic cardiovascular disease and in healthy volunteers. The patients with a history of CVEs had significantly higher LIP values than did the control group (1.94+/-0.46 microM vs. 1.62+/-0.49 microM, p=0.02). Except for the leukocyte number (WBCs), the groups did not differ in other inflammatory markers (CRPus, CD 163, MPO, MMP-1)...
October 26, 2016: Physiological Research
https://www.readbyqxmd.com/read/27773270/kinetic-improvement-of-olive-leaves-bioactive-compounds-extraction-by-using-power-ultrasound-in-a-wide-temperature-range
#5
Ibtihel Khemakhem, Margarita Hussam Ahmad-Qasem, Enrique Barrajón Catalán, Vicente Micol, Jose Vicente García-Pérez, Mohamed Ali Ayadi, Mohamed Bouaziz
In this study, the effect of temperature and ultrasonic application on extraction kinetics of polyphenols from dried olive leaf was investigated. Conventional (CVE) and ultrasonic-assisted extraction (UAE) were performed at 10, 20, 30, 50 and 70°C using water as solvent. Extracts were characterized by measuring the total phenolic content, the antioxidant capacity and the oleuropein content (HPLC-DAD/MS-MS). Moreover, Naik's model was used to mathematically describe the extraction kinetics. The experimental results showed that phenolic extraction was faster in UAE (ultrasonic-assisted extraction) than in CVE (conventional extraction), being extraction kinetics satisfactorily described using Naik model (include VAR>98%)...
January 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/27754191/sp-05-4-implications-of-the-sprint-trial-asian-perspective
#6
Sadayoshi Ito
SPRINT is one of the landmark studies, demonstrating that extensive blood pressure (BP) control (BP < 120 mmHg) is superior to standard control (BP < 140 mmHg) in preventing cardiovascular event (CVE). Subjects recruited were older than 50 years without diabetes and had increased risk of CVE. Heart failure, death from cardiovascular cause and death from any cause were major endpoints reduced by extensive BP control. In subgroup analysis, whole spectrum of patients were benefitted. Contrary to several previous studies, this study provides strong evidence for the beneficial effect of extensive BP reduction...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27744013/use-of-healthcare-resources-and-costs-associated-to-the-start-of-treatment-with-injectable-drugs-in-patients-with-type-2-diabetes-mellitus
#7
Antoni Sicras-Mainar, Ruth Navarro-Artieda, Raúl Morano, Lucía Ruíz
OBJECTIVES: The main objective was to assess resource use and costs of starting treatment with insulin or injectable GLP-1 receptor analogues (GLP-1 RAs) in a Spanish population of patients with type 2 diabetes mellitus. Treatment adherence and persistence were also determined for both treatment groups. PATIENTS AND METHODS: A retrospective, non-interventional, observational study was conducted. Patients aged ≥20 years who started treatment with insulin or GLP-1 RAs in the 2010-2012 period were recruited...
December 2016: Endocrinología y Nutrición: órgano de la Sociedad Española de Endocrinología y Nutrición
https://www.readbyqxmd.com/read/27725593/the-importance-of-taking-late-cardiovascular-toxicity-induced-by-tki-into-consideration-in-patients-with-cml
#8
Naoto Takahashi
BCR-ABL tyrosine kinase inhibitor (TKI) has dramatically improved the prognosis of CML patients. Now, one of the most important factors with a marked effect on prognosis in CML patients is having a comorbidity. Recently, cardiovascular events (CVE) have been reported in some clinical trials as a late toxicity of TKI, which might be associated with off-target of TKI, ABL/ARG, PDGFR and VEGFR. Because TKI-associated CVE is one of the potentially lethal adverse events associated with TKI administration, hematologists must practice the "ABCDE steps" for CML patients treated with second generation TKI in collaboration with cardiologists...
2016: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/27646783/characterization-and-cholesterol-management-in-patients-with-cardiovascular-events-and-or-type-2-diabetes-in-the-netherlands
#9
Edith Heintjes, Josephina Kuiper, Bianca Lucius, Fernie Penning-van Beest, Lucie Kutikova, Anho Liem, Ron Herings
OBJECTIVE: To describe clinical characteristics and cholesterol management of patients with cardiovascular events (CVEs) and/or type 2 diabetes mellitus (T2DM) with high low-density lipoprotein cholesterol (LDL-C) > 1.8 mmol/L in the Netherlands. RESEARCH DESIGN AND METHODS: From the PHARMO Database Network a cross-sectional cohort was constructed. The descriptive study included patients on lipid modifying therapy (LMT) in 2009, classified as high cardiovascular risk based on a history of T2DM or CVE, with 2010 LDL-C levels above 1...
September 29, 2016: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/27643148/sp-05-4-implications-of-the-sprint-trial-asian-perspective
#10
Sadayoshi Ito
SPRINT is one of the landmark studies, demonstrating that extensive blood pressure (BP) control (BP < 120 mmHg) is superior to standard control (BP < 140 mmHg) in preventing cardiovascular event (CVE). Subjects recruited were older than 50 years without diabetes and had increased risk of CVE. Heart failure, death from cardiovascular cause and death from any cause were major endpoints reduced by extensive BP control. In subgroup analysis, whole spectrum of patients were benefitted. Contrary to several previous studies, this study provides strong evidence for the beneficial effect of extensive BP reduction...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27639744/in-vitro-evaluation-of-implantation-depth-in-valve-in-valve-using-different-transcatheter-heart-valves
#11
Matheus Simonato, Ali N Azadani, John Webb, Jonathon Leipsic, Ran Kornowski, Alec Vahanian, David Wood, Nicolo Piazza, Susheel Kodali, Jian Ye, Brian Whisenant, Diego Gaia, Mina Aziz, Tilak Pasala, Julinda Mehilli, Harindra C Wijeysundera, Didier Tchetche, Neil Moat, Rui Teles, Anna Sonia Petronio, David Hildick-Smith, Uri Landes, Stephan Windecker, Yaron Arbel, Oscar Mendiz, Raj Makkar, Elaine Tseng, Danny Dvir
AIMS: Transcatheter heart valve (THV) implantation in failed bioprosthetic valves (valve-in-valve [ViV]) offers an alternative therapy for high-risk patients. Elevated post-procedural gradients are a significant limitation of aortic ViV. Our objective was to assess the relationship between depth of implantation and haemodynamics. METHODS AND RESULTS: Commercially available THVs used for ViV were included in the analysis (CoreValve Evolut, SAPIEN XT and the Portico valve)...
September 18, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27542792/aortic-atheroma-burden-predicts-acute-cerebrovascular-events-after-transcatheter-aortic-valve-implantation-insights-from-volumetric-multislice-computed-tomography-analysis
#12
Yu Kataoka, Rishi Puri, Anthony D Pisaniello, Muhammad Hammadah, Mohammed Qintar, Kiyoko Uno, Joseph K Montarello, Stephen J Nicholls, Stephen G Worthley
AIMS: Embolisation of atheromatous debris during catheter manipulation is considered to underlie acute cerebrovascular events (CVE) after transcatheter aortic valve implantation (TAVI). However, the relationship between aorta atheroma burden and acute CVE after TAVI has not been established. We investigated the impact of aorta atheroma burden on acute CVE. METHODS AND RESULTS: Preoperative multislice computed tomographic (MSCT) images in 278 patients receiving TAVI were analysed...
August 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27517679/clinical-effects-and-safety-of-direct-acting-insulin-analogs-in-patients-with-type-1-diabetes-a-nation-wide-observational-cohort-study
#13
Vincent Lak, Ann-Marie Svensson, Mervete Miftaraj, Stefan Franzén, Björn Eliasson
INTRODUCTION: Studies comparing direct-acting insulin analogs (DAIs) in terms of effectiveness and long-term safety are scarce. Our aim was to explore these variables in clinical practice among patients with type 1 diabetes, including the elderly and those with renal impairment. METHODS: We linked four national registers in a population-based cohort study. Patients with type 1 diabetes and continuous use of all currently available DAIs (lispro, aspart, or glulisine) in 2005-2013 were monitored for up to 7...
September 2016: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/27515325/predictors-of-early-cerebrovascular-events-in-patients-with-aortic-stenosis-undergoing-transcatheter-aortic-valve%C3%A2-replacement
#14
Vincent Auffret, Ander Regueiro, María Del Trigo, Omar Abdul-Jawad Altisent, Francisco Campelo-Parada, Olivier Chiche, Rishi Puri, Josep Rodés-Cabau
BACKGROUND: Identifying transcatheter aortic valve replacement (TAVR) patients at high risk for cerebrovascular events (CVE) is of major clinical relevance. However, predictors have varied across studies. OBJECTIVES: The purpose of this study was to analyze the predictors of 30-day CVE post-TAVR. METHODS: A systematic review of studies that reported the incidence of CVE post-TAVR while providing raw data for predictors of interest was performed...
August 16, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27508857/-op-8a-05-regular-physical-activity-attenuates-the-association-between-coffee-consumption-and-cardiovascular-events-in-hypertension-the-harvest
#15
L Mos, C Fania, F Saladini, A Mazzer, S Cozzio, A Bortolazzi, G Garavelli, E Casiglia, P Palatini
OBJECTIVE: Coffee consumption has been found to predict the risk of cardiovascular events (CVE) in hypertension. Aim of the present study was to ascertain whether the strength of the coffee-CVE association is modulated by regular physical activity. DESIGN AND METHOD: The analysis was made in 1204 participants from the HARVEST, a prospective cohort study of non-diabetic subjects aged 18-45 years, screened for stage 1 hypertension. Among the participants, 26.2% were abstainers, 62...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508753/-op-5c-06-masked-tachycardia-predicts-adverse-outcome-in-hypertension-the-abp-international-study
#16
P Palatini, P Reboldi, S Pierdomenico, K Eguchi, K Kario, Y Imai, T Ohkubo, L Beilin, L Wing, J Schwartz, E Casiglia, P Verdecchia
OBJECTIVE: Heart rate (HR) is a well known predictor of cardiovascular events (CVE) and mortality but the relative role of resting office HR and ambulatory HR for predicting these outcomes is not well known. Aim of this study was to investigate the association of white-coat tachycardia and masked tachycardia with CVE and all-cause mortality in hypertensive subjects. DESIGN AND METHOD: We performed 24-hour ambulatory blood pressure and HR monitoring in 7602 hypertensive patients (4165 men) aged 52 ± 16 years enrolled in 8 prospective studies in Italy, U...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508745/-op-1b-05-over-24h-central-pulse-pressure-is-superior-to-peripheral-pulse-pressure-for-cardiovascular-events-prediction-results-from-the-bordeaux-hypertensive-cohort
#17
A Cremer, R Boulestreau, P Gosse
OBJECTIVE: Hypertension still remains the main cardiovascular risk factor. Given its high prevalence, identification of patients with the higher risk of facing a cardiovascular event (CVE) is matter of concern. Several tools have been proposed. In particular ambulatory blood pressure (BP) measurement has proven its superiority to office BP but other parameters like arterial stiffness measurement as well as central BP may contribute to a better risk level assessment. To date, there is no data about the potential interest of 24-H non invasive central BP recording for CVE prediction...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27497736/sclerostin-cardiovascular-disease-and-mortality-a-systematic-review-and-meta-analysis
#18
Mehmet Kanbay, Yalcin Solak, Dimitrie Siriopol, Gamze Aslan, Baris Afsar, Dilek Yazici, Adrian Covic
BACKGROUND AND AIM: Chronic kidney disease mineral and bone disorder (CKD-MBD) is associated with increased morbidity and mortality. Several cross-sectional studies investigated the association of serum sclerostin levels with mortality and vascular calcification. We aimed to investigate the effect of sclerostin on cardiovascular events (CVE), all-cause/cardiovascular mortality and vascular calcification in patients with CKD through systematic review and meta-analysis. The primary outcome was the association between sclerostin level and development of fatal and nonfatal CVE and all-cause mortality...
August 6, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27458623/-interleukin-6-inhibition-and-cardiovascular-disease-in-patients-with-rheumatoid-arthritis
#19
REVIEW
T V Popkova, D S Novikova, E L Nasonov
Rheumatoid arthritis (RA) is a' disease conferring high risk for cardiovascular events (CVE). Systemic inflammation underlying RA favors development of CVE. The safety of biological agents, acting on the cardiovascular system has been inadequately investigated. On the one hand, they decrease RA activity and, on the other, may increase the risk of CVE. This review analyzes' the literature data predominantly published in recent years on the effect of an IL-6 receptor inhibitor on the cardiovascular system. Tocilizumab is shown to be a promising agent to reduce cardiovascular risk the findings need to be clinically verified...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27424685/cardiovascular-disease-risk-profiles-comparison-among-dialysis-patients
#20
Islam Sharabas, Nauman Siddiqi
This study was performed to assess the cardiovascular disease (CVD) risk factors in the prevalent peritoneal dialysis (PD) and hemodialysis (HD) patients and their association with cardiovascular events (CVEs) in a Saudi end-stage renal disease cohort. This was a prospective, observational, single-center study. A total of 192 patients were screened of which 157 patients were eligible (HD = 121, PD = 36). All patients underwent assessment of cardiovascular risk factors at the time of enrollment including electrocardiogram and echocardiography, lipid profile, homocysteine, and insulin levels...
July 2016: Saudi Journal of Kidney Diseases and Transplantation
keyword
keyword
53170
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"