keyword
https://read.qxmd.com/read/38531143/characterizing-cognitive-subtypes-in-schizophrenia-using-cortical-curvature
#21
JOURNAL ARTICLE
Irina Papazova, Stephan Wunderlich, Boris Papazov, Ulrike Vogelmann, Daniel Keeser, Temmuz Karali, Peter Falkai, Susanne Rospleszcz, Isabel Maurus, Andrea Schmitt, Alkomiet Hasan, Berend Malchow, Sophia Stöcklein
Cognitive deficits are a core symptom of schizophrenia, but research on their neural underpinnings has been challenged by the heterogeneity in deficits' severity among patients. Here, we address this issue by combining logistic regression and random forest to classify two neuropsychological profiles of patients with high (HighCog) and low (LowCog) cognitive performance in two independent samples. We based our analysis on the cortical features grey matter volume (VOL), cortical thickness (CT), and mean curvature (MC) of N = 57 patients (discovery sample) and validated the classification in an independent sample (N = 52)...
March 21, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38531063/parallel-continuous-monitoring-and-quantification-of-programmed-cell-death-in-plant-tissue
#22
JOURNAL ARTICLE
Alexander Silva Pinto Collins, Hasan Kurt, Cian Duggan, Yasin Cotur, Philip Coatsworth, Atharv Naik, Matti Kaisti, Tolga Bozkurt, Firat Güder
Accurate quantification of hypersensitive response (HR) programmed cell death is imperative for understanding plant defense mechanisms and developing disease-resistant crop varieties. Here, a phenotyping platform for rapid, continuous-time, and quantitative assessment of HR is demonstrated: Parallel Automated Spectroscopy Tool for Electrolyte Leakage (PASTEL). Compared to traditional HR assays, PASTEL significantly improves temporal resolution and has high sensitivity, facilitating detection of microscopic levels of cell death...
March 26, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38530559/accuracy-of-machine-learning-in-the-diagnosis-of-odontogenic-cysts-and-tumors-a-systematic-review-and-meta-analysis
#23
REVIEW
Priyanshu Kumar Shrivastava, Shamimul Hasan, Laraib Abid, Ranjit Injety, Ayush Kumar Shrivastav, Deborah Sybil
BACKGROUND: The recent impact of artificial intelligence in diagnostic services has been enormous. Machine learning tools offer an innovative alternative to diagnose cysts and tumors radiographically that pose certain challenges due to the near similar presentation, anatomical variations, and superimposition. It is crucial that the performance of these models is evaluated for their clinical applicability in diagnosing cysts and tumors. METHODS: A comprehensive literature search was carried out on eminent databases for published studies between January 2015 and December 2022...
March 26, 2024: Oral Radiology
https://read.qxmd.com/read/38530215/fragmentation-of-the-qrs-complex-is-associated-with-right-ventricular-dilatation-and-mortality-in-critically-unwell-coronavirus-disease-2019-patients
#24
JOURNAL ARTICLE
Randeep S Heer, Faye L Selby, Amit J K Mandal, Vadir Baktash, Piotr Szawarski, Sirtaaj Mattoo, Hasan Mohiaddin, Kanchani K Makuloluwa, Hussein Chreif, Fouad R Amin, Constantinos G Missouris
BACKGROUND: QRS fragmentation (fQRS) is a depolarization disorder that can be detected on routine electrocardiography (ECG). Current evidence suggests that fQRS is a prognosticator of adverse cardiovascular events. This study aimed to assess the relationship between fQRS and all-cause mortality in critically unwell coronavirus disease 2019 (COVID-19) patients and to investigate the significance of associated abnormalities on echocardiography. METHODS: A retrospective cohort study of COVID-19 patients in a critical care setting was performed...
March 26, 2024: Anatolian Journal of Cardiology
https://read.qxmd.com/read/38529780/increased-rates-of-hospital-onset-staphylococcus-aureus-bacteraemia-in-national-health-service-acute-trusts-in-england-between-june-2020-and-march-2021-a-national-surveillance-review
#25
JOURNAL ARTICLE
E Mason, O Nsonwu, J Elmes, D Chudasama, C Pearson, L Hasan, R Hope, S M Gerver
A large increase in hospital-onset and intensive-care-unit-onset Staphylococcus aureus bacteraemia rates in English acute trusts was observed between 2020 and 2021, coinciding with reported increases in coronavirus disease (COVID-19) cases and associated hospitalizations. Many of these S. aureus bacteraemia cases were defined as co-/secondary infections to COVID-19. Over the same period, increases in the percentage of ventilator-associated pneumonia-related bacteraemia were also found. The COVID-19 pandemic appears to have contributed to the increase in hospital-onset S...
January 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38529548/exploring-multiple-endocrinological-issues-and-dysautonomia-in-a-rare-case-hypoparathyroidism-in-mirage-syndrome
#26
JOURNAL ARTICLE
Sirmen Kızılcan Çetin, Elif Özsu, Zeynep Şıklar, Hasan Fatih Çakmaklı, Gizem Şenyazar, Zehra Aycan, Serdar Ceylaner, Merih Berberoğlu
MIRAGE syndrome is a rare multisystemic disorder characterized by various manifestations, such as myelodysplasia, susceptibility to infections, growth retardation, adrenal hypoplasia, genital anomalies, and enteropathy. In the literature, there have been rare cases of dysautonomia. We present a 6.5-year-old girl, who was first admitted to our department with short stature. On follow up, she exhibited multiple endocrinological issues, including transient hypothyroidism, primary hypoparathyroidism and dysautonomia, along with multisystem involvement...
March 26, 2024: Journal of Clinical Research in Pediatric Endocrinology
https://read.qxmd.com/read/38529535/metal-to-semiconductor-switching-in-the-agte-monolayer-via-decoration-with-alkali-metal-and-alkaline-earth-metal-atoms-a-first-principles-perspective
#27
JOURNAL ARTICLE
A Bafekry, M M Fadlallah, M Faraji, S Hasan Khan, H R Jappor, Babak Shokri, M Ghergherehchi, Gap Soo Chang
In this work, employing first-principles calculations, we systematically investigate the atomic structure and electronic and optical properties of the AgTe monolayer, as well as the impact of alkali metal (Li, Na, K) and alkaline earth metal (Be, Mg, Ca) atoms decoration. The AgTe monolayer exhibits metallic characteristics. When Li, Na, K, and Mg atoms are decorated on the AgTe monolayer, the decorated AgTe monolayers are dynamically stable. In contrast, with Be and Ca atoms, the decorated structures are found to be dynamically unstable...
March 26, 2024: Physical Chemistry Chemical Physics: PCCP
https://read.qxmd.com/read/38529445/rectal-sedation-with-ketamine-and-midazolam-in-the-management-of-uncooperative-children-during-dental-treatment-a-case-series-and-method-description
#28
JOURNAL ARTICLE
Hasan Alzoubi, Samar Kabbani, Ahmad Taleb, Nada Bshara, Mohamed K Altinawi, Mohammed Bashier Almonakel, Saleh Al Kurdi
Background In pediatric dentistry, sedation aims to eliminate anxiety to facilitate the completion of dental procedures. Sedation in children is a multidimensional field that includes the child, parents/guardians, and the health care team. The rectal route is generally painless, making it suitable for children who are afraid of needles. This route has several advantages over the oral route, including reduced patient cooperation requirements, a faster and more predictable onset, and less physical trauma than the intravenous and intramuscular routes...
February 2024: Curēus
https://read.qxmd.com/read/38529429/hypernatremia-and-its-rate-of-correction-the-evidence-so-far
#29
REVIEW
Sindhu C Pokhriyal, Prachi Joshi, Uma Gupta, Pulok Roy, Sunil Parkash, Kalendra Kunwar, Muthanna Mohammed Hasan Al-Ghuraibawi, Sagar Nagpal, Ruchi Yadav, Kalpana Panigrahi
Hypernatremia or high serum sodium levels can have many different causes, including insufficient free water intake, or excess free water losses. The management of hypernatremia focuses on resolving the underlying cause, replenishing free water deficit, and preventing further losses while closely monitoring serum sodium concentration. This systematic review was carried out using medical databases such as PubMed, PubMed Central, and Google Scholar for relevant medical literature. The identified articles were reviewed, eligibility criteria were applied, and seven research articles were identified...
February 2024: Curēus
https://read.qxmd.com/read/38529118/addressing-bias-in-the-definition-of-sars-cov-2-reinfection-implications-for-underestimation
#30
JOURNAL ARTICLE
Hiam Chemaitelly, Houssein H Ayoub, Patrick Tang, Hadi M Yassine, Asmaa A Al Thani, Mohammad R Hasan, Peter Coyle, Zaina Al-Kanaani, Einas Al-Kuwari, Andrew Jeremijenko, Anvar Hassan Kaleeckal, Ali Nizar Latif, Riyazuddin Mohammad Shaik, Hanan F Abdul-Rahim, Gheyath K Nasrallah, Mohamed Ghaith Al-Kuwari, Adeel A Butt, Hamad Eid Al-Romaihi, Mohamed H Al-Thani, Abdullatif Al-Khal, Roberto Bertollini, Laith J Abu-Raddad
INTRODUCTION: Reinfections are increasingly becoming a feature in the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, accurately defining reinfection poses methodological challenges. Conventionally, reinfection is defined as a positive test occurring at least 90 days after a previous infection diagnosis. Yet, this extended time window may lead to an underestimation of reinfection occurrences. This study investigated the prospect of adopting an alternative, shorter time window for defining reinfection...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38529099/clinical-presentation-and-6-month-outcomes-of-patients-with-peripartum-cardiomyopathy-in-indonesia
#31
JOURNAL ARTICLE
Hawani Sasmaya Prameswari, Triwedya Indra Dewi, Melawati Hasan, Erwan Martanto, Astri Astuti, Aninka Saboe, Charlotte Johanna Cool
BACKGROUND: Due to the rarity of peripartum cardiomyopathy (PPCM) globally, baseline characteristic data for PPCM patients are still scarce. Therefore, this study aims to determine the baseline characteristics and 6-month outcomes of PPCM patients in Indonesia. METHODS: From January 2014 to December 2021, all PPCM patients aged ≥18 years who were admitted to Dr. Hasan Sadikin General Hospital in Bandung, Indonesia, participated in this single-center, prospective cohort study...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38528927/band-gap-engineering-in-lead-free-halide-cubic-perovskites-gagex-3-x-cl-br-and-i-based-on-first-principles-calculations
#32
JOURNAL ARTICLE
Md Amran Sarker, Md Mehedi Hasan, Md Al Momin, Ahmad Irfan, Md Rasidul Islam, Ahmed Sharif
Lead-free inorganic Ge-based perovskites GaGeX3 (X = Cl, Br, and I) are promising candidates for solar cell applications due to their structural, mechanical, electrical, and optical properties. In this work, we performed density functional theory (DFT) calculations using the CASTEP module to investigate these properties in detail. We found that the lattice parameters and cell volumes increase with the size of the halogen atoms, and that all the compounds are stable and ductile. GaGeBr3 has the highest ductility, machinability, and lowest hardness, while GaGeCl3 has the highest anisotropy...
March 20, 2024: RSC Advances
https://read.qxmd.com/read/38528656/altered-placental-immune-cell-composition-and-gene-expression-with-isolated-fetal-spina-bifida
#33
JOURNAL ARTICLE
Marina White, Hasan Abdo, David Grynspan, Tim Van Mieghem, Kristin L Connor
PROBLEM: Fetal spina bifida (SB) is more common in pregnant people with folate deficiency or anomalies of folate metabolism. It is also known that fetuses with SB have a higher risk of low birthweight, a condition that is typically placental-mediated. We therefore hypothesized that fetal SB would associate with altered expression of key placental folate transporters and an increase in Hofbauer cells (HBCs), which are folate-dependent placental macrophages. METHOD OF STUDY: Folate receptor-α (FRα), proton coupled folate receptor (PCFT), and reduced folate carrier (RFC) protein localization and expression (immunohistochemistry) and HBC phenotypes (HBC abundance and folate receptor-β [FRβ] expression; RNA in situ hybridization) were assessed in placentae from fetuses with SB (cases; n = 12) and in term (n = 10) and gestational age (GA) - and maternal body mass index - matched (n = 12) controls without congenital anomalies...
March 2024: American Journal of Reproductive Immunology: AJRI
https://read.qxmd.com/read/38528161/preoperative-fatty-infiltration-of-paraspinal-muscles-assessed-by-mri-is-associated-with-less-improvement-of-leg-pain-2%C3%A2-years-after-surgery-for-lumbar-spinal-stenosis
#34
JOURNAL ARTICLE
Hasan Banitalebi, Erland Hermansen, Christian Hellum, Ansgar Espeland, Kjersti Storheim, Tor Åge Myklebust, Kari Indrekvam, Helena Brisby, Clemens Weber, Masoud Anvar, Jørn Aaen, Anne Negård
PURPOSE: Fatty infiltration (FI) of the paraspinal muscles may associate with pain and surgical complications in patients with lumbar spinal stenosis (LSS). We evaluated the prognostic influence of MRI-assessed paraspinal muscles' FI on pain or disability 2 years after surgery for LSS. METHODS: A muscle fat index (MFI) was calculated (by dividing signal intensity of psoas to multifidus and erector spinae) on preoperative axial T2-weighted MRI of patients with LSS...
March 25, 2024: European Spine Journal
https://read.qxmd.com/read/38526832/impact-of-18f-fdg-pet-ct-and-laparoscopy-in-staging-of-locally-advanced-gastric-cancer-a-cost-analysis-in-the-prospective-multicenter-plastic-study
#35
JOURNAL ARTICLE
Cas de Jongh, Miriam P van der Meulen, Emma C Gertsen, Hylke J F Brenkman, Johanna W van Sandick, Mark I van Berge Henegouwen, Suzanne S Gisbertz, Misha D P Luyer, Grard A P Nieuwenhuijzen, Jan J B van Lanschot, Sjoerd M Lagarde, Bas P L Wijnhoven, Wobbe O de Steur, Henk H Hartgrink, Jan H M B Stoot, Karel W E Hulsewe, Ernst Jan Spillenaar Bilgen, Marc J van Det, Ewout A Kouwenhoven, Freek Daams, Donald L van der Peet, Nicole C T van Grieken, Joos Heisterkamp, Boudewijn van Etten, Jan-Willem van den Berg, Jean-Pierre Pierie, Hasan H Eker, Annemieke Y Thijssen, Eric J T Belt, Peter van Duijvendijk, Eelco Wassenaar, Kevin P Wevers, Lieke Hol, Frank J Wessels, Nadia Haj Mohammad, Geert W J Frederix, Richard van Hillegersberg, Peter D Siersema, Erik Vegt, Jelle P Ruurda
BACKGROUND: Unnecessary D2-gastrectomy and associated costs can be prevented after detecting non-curable gastric cancer, but impact of staging on treatment costs is unclear. This study determined the cost impact of 18 F-fluorodeoxyglucose positron emission tomography/computed tomography (18F FDG-PET/CT) and staging laparoscopy (SL) in gastric cancer staging. MATERIALS AND METHODS: In this cost analysis, four staging strategies were modeled in a decision tree: (1) 18F FDG-PET/CT first, then SL, (2) SL only, (3) 18F FDG-PET/CT only, and (4) neither SL nor 18F FDG-PET/CT...
March 25, 2024: Annals of Surgical Oncology
https://read.qxmd.com/read/38525788/calling-the-question-what-is-mammalian-transgenerational-epigenetic-inheritance
#36
JOURNAL ARTICLE
Hasan Khatib, Jessica Townsend, Melissa A Konkel, Gabi Conidi, Julia A Hasselkus
While transgenerational epigenetic inheritance has been extensively documented in plants, nematodes, and fruit flies, its existence in mammals remains controversial. Several factors have contributed to this debate, including the lack of a clear distinction between intergenerational and transgenerational epigenetic inheritance (TEI), the inconsistency of some studies, the potential confounding effects of in-utero vs. epigenetic factors, and, most importantly, the biological challenge of epigenetic reprogramming...
December 2024: Epigenetics: Official Journal of the DNA Methylation Society
https://read.qxmd.com/read/38525738/epigenetic-features-in-newborns-associated-with-preadolescence-lung-function-and-asthma-acquisition-during-adolescence
#37
JOURNAL ARTICLE
Mohammad Nahian Ferdous Abrar, Yu Jiang, Hongmei Zhang, Liang Li, Hasan Arshad
UNLABELLED: The association between newborn DNA methylation (DNAm) and asthma acquisition (AA) during adolescence has been suggested. Lung function (LF) has been shown to be associated with asthma risk and its severity. However, the role of LF in the associations between DNAm and AA is unclear, and it is also unknown whether the association between DNAm and AA is consistent with that between DNAm and LF. We address this question through assessing newborn epigenetic features of preadolescence LF and of AA during adolescence, along with their biological pathways and processes...
March 22, 2024: Epigenomes
https://read.qxmd.com/read/38525716/anxiety-and-depression-and-associated-risk-factors-among-outpatients-with-systemic-lupus-erythematosus-eastern-province-saudi-arabia
#38
JOURNAL ARTICLE
Manal Ahmed Hasan, Wasayf Salman Almogaliq, Fatimah Habib Alhanabi, Hebah Abbas Aldrazi, Moath Thamer Alkhouzaie, Raed Albukhari, Safi Alqatari, Abdullah A Al-Abdulwahab, Hajer Musaab AlZuhair, Mohammed T Al-Hariri
BACKGROUND: Although mood disorders are prevalent among systemic lupus erythematosus (SLE) patients, they are usually underrecognized. This study aimed to estimate the prevalence of anxiety and depression among Saudi SLE patients. METHODS: This cross-sectional study was conducted among SLE patients from July 2022 to June 2023 in the Eastern Province of Saudi Arabia. A self-reported questionnaire was used to collect the data through validated tools including the Hamilton Anxiety Rating Scale-A and the Beck Depression Inventory score...
March 19, 2024: Clinics and Practice
https://read.qxmd.com/read/38525535/treatment-of-multidrug-resistant-or-rifampicin-resistant-tuberculosis-with-an-all-oral-9-month-regimen-containing-linezolid-or-ethionamide-in-south-africa-a-retrospective-cohort-study
#39
JOURNAL ARTICLE
Hannah Morgan, Norbert Ndjeka, Tasnim Hasan, Medea Gegia, Fuad Mirzayev, Linh Nguyen, Samuel Schumacher, Timothy E Schlub, Kogieleum Naidoo, Greg J Fox
BACKGROUND: In 2019, the South African tuberculosis program replaced ethionamide with linezolid as a part of an all-oral 9-month regimen. We evaluated treatment outcomes for patients assigned to regimens including linezolid in 2019 and ethionamide in 2017. METHOD: This retrospective cohort study included patients treated for multi-drug resistant/rifampicin-resistant tuberculosis throughout South Africa between 1 Jan to 31 Dec 2017 and from 1 Jan to 31 Dec 2019. The cohort treated with a 9-month regimen containing ethionamide for four months, was compared with a cohort treated with a 9-month regimen containing linezolid for two months...
March 25, 2024: Clinical Infectious Diseases
https://read.qxmd.com/read/38525505/investigation-into-a-new-denervation-model-of-the-sciatic-nerve-zones-in-rats-selective-motor-or-sensorial-denervation
#40
JOURNAL ARTICLE
Selman Hakkı Altuntaş, Levent Sarikcioglu, Hasan Rifat Koyuncuoğlu, İbrahim Metin Çiriş, Fuat Uslusoy, Osman Gurdal, Mustafa Asım Aydın
OBJECTIVE: This study aimed to introduce a reliable and useful model of selective sensorial or motor denervations of the sciatic nerve in rats with clinical and laboratory outcomes. METHODS: The surgical technique was determined via detailed cadaveric dissections of rat sciatic nerve roots and cross-sectional histoanatomy. Forty animals were divided into the sham, sensorial denervation (SD), motor denervation (MD), and combined denervation (CD) groups and evaluated clinically via the pinch test and observation...
January 2024: Acta Orthopaedica et Traumatologica Turcica
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