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https://www.readbyqxmd.com/read/29793101/-survey-of-wellbeing-of-young-children-swyc-how-does-it-fit-for-screening-developmental-delay-in-brazilian-children-aged-4-to-58-months
#1
R S Moreira, L C Magalhães, C M Siqueira, C R L Alves
OBJECTIVE: To replicate the original normative study of the SWYC's Milestones Questionnaires for children in Brazil. Our goals were to compare the performance of Brazilian and North American children using this screening tool and to verify the reliability and validity of the Brazilian version. STUDY DESIGN AND SETTING: Cross-sectional study with children aged 1-65 months and their guardians, recruited in southern Brazil. Parents were interviewed using the Developmental Milestones questionnaire, which contains 10 questions about cognitive, motor, social, and language abilities...
May 21, 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29792476/a-mixed-methods-investigation-into-the-perspectives-on-mental-health-and-professional-treatment-among-former-system-youth-with-mood-disorders
#2
Michelle R Munson, Sarah Carter Narendorf, Shelly Ben-David, Andrea Cole
Research has shown that how people think about their health (or illnesses) shapes their help-seeking behavior. In this mixed-methods study, we employed a simultaneous concurrent design to explore the perceptions of mental illness among an understudied population: marginalized young adults. Participants were 60 young adults (ages 18-25) who had experienced mood disorders and used multiple public systems of care during their childhoods. Semistructured interviews were conducted to understand participants' illness and treatment experiences during the transition to adulthood...
May 24, 2018: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/29792165/molecular-characterization-and-differential-expression-suggested-diverse-functions-of-p-type-ii-ca-2-atpases-in-triticum-aestivum-l
#3
Mehak Taneja, Santosh Kumar Upadhyay
BACKGROUND: Plant P-type II Ca2+ ATPases are formed by two distinct groups of proteins (ACAs and ECAs) that perform pumping of Ca2+ outside the cytoplasm during homeostasis, and play vital functions during development and stress management. In the present study, we have performed identification and characterisation of P-type II Ca 2+ ATPase gene family in an important crop plant Triticum aestivum. RESULTS: Herein, a total of 33 TaACA and 9 TaECA proteins were identified from the various chromosomes and sub-genomes of Triticum aestivum...
May 23, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29791739/what-implementation-evidence-matters-scaling-up-nurturing-interventions-that-promote-early-childhood-development
#4
Pia R Britto, Manpreet Singh, Tarun Dua, Raghbir Kaur, Aisha K Yousafzai
Research in early childhood development (ECD) has established the need for scaling-up multisectoral interventions for nurturing care to promote ECD, for improved socioeconomic outcomes for sustainable societies. However, key elements and processes for implementation and scale-up of such interventions are not well understood. This special series on implementation research and practice for ECD brings together evidence to inform effectiveness, quality, and scale in nurturing care programs; identifies knowledge gaps; and proposes further directions for research and practice...
May 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29791733/implementation-research-for-early-childhood-development-programming-in-humanitarian-contexts
#5
Katie Maeve Murphy, Hirokazu Yoshikawa, Alice J Wuermli
Young children living in conditions of war, disaster, and displacement are at high risk for developmental difficulties that can follow them throughout their lives. While there is robust evidence supporting the need for early childhood development (ECD) in humanitarian settings, implementation of ECD programming remains sparse, largely due to the lack of evidence of how and why these programs can improve outcomes in humanitarian settings. In order to build the evidence base for ECD in humanitarian settings, we review the current state of implementation research for ECD programming (targeting children 0-8) in humanitarian settings, through a literature review and a series of key informant interviews...
May 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29791647/active-methodologies-for-graduation-in-nursing-focus-on-the-health-care-of-older-adults
#6
Elaine Fernanda Dornelas de Souza, Amanda Gaspar Silva, Ariana Ieda Lima Ferreira da Silva
OBJECTIVE: To describe the experience of the use of simulation as active teaching methodology in the Developmental Psychology discipline and share its impacts on the students' learning process. METHOD: Based on Active Methodologies, the students in Nursing of Universidade do Oeste Paulista - Presidente Prudente-SP developed simulated visits to older users of the Family Health Strategies. RESULTS: In accordance with the 2014 National Curriculum Guidelines and the Brazilian Unified Health System, particularities of the needs of older adults at their homes were problematized...
2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29791184/expert-exchange-workgroup-on-children-aged-5-and-younger-with-severe-obesity-a-narrative-review-of-medical-and-genetic-risk-factors
#7
Nazrat Mirza, Thao-Ly Phan, June Tester, Angela Fals, Cristina Fernandez, George Datto, Elizabeth Estrada, Ihuoma Eneli
Severe obesity defined as an age- and gender-specific body mass index ≥120% of the 95th percentile in children younger than 5 years is well recognized as a significant challenge for prevention and treatment. This article provides an overview of the prevalence, classification of obesity severity, patterns of weight gain trajectory, medical and genetic risk factors, and comorbid disorders among young children with an emphasis on severe obesity. Studies suggest rapid weight gain trajectory in infancy, maternal smoking, maternal gestational diabetes, and genetic conditions are associated with an increased risk for severe obesity in early childhood...
May 23, 2018: Childhood Obesity
https://www.readbyqxmd.com/read/29790773/decisions-on-repositioning-of-intruded-permanent-incisors-a-review-and-case-presentation
#8
E Hurley, C Stewart, C Gallagher, M Kinirons
Traumatic intrusion is a luxation type of injury where the tooth is displaced along the axis of the tooth, into the alveolus. This injury is regarded as serious because of the tissue damage that it causes. The traumatic movement is associated with severe damage to the periodontal ligament, pulpal tissue, root and alveolar socket. Despite its severity, the rare occurrence of this injury in permanent teeth has resulted in limited studies of immature and mature permanent incisors. The purpose of this paper is to review this luxation injury of permanent immature incisors, and to describe its diagnosis, treatment and management...
June 2018: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29789029/pediatric-brain-development-in-down-syndrome-a-field-in-its-infancy
#9
Taralee Hamner, Manisha D Udhnani, Karol Z Osipowicz, Nancy Raitano Lee
OBJECTIVES: As surprisingly little is known about the developing brain studied in vivo in youth with Down syndrome (DS), the current review summarizes the small DS pediatric structural neuroimaging literature and begins to contextualize existing research within a developmental framework. METHODS: A systematic review of the literature was completed, effect sizes from published studies were reviewed, and results are presented with respect to the DS cognitive behavioral phenotype and typical brain development...
May 23, 2018: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29788537/ten-years-of-medical-education-registrars-value-added
#10
Victoria Brazil, Lorna Davin
OBJECTIVE: There is a paucity of any long-term follow up of trainees' career pathways or organisational outcomes from medical education registrar posts in emergency medicine training. We report on the experience of a selected group of medical education trainees during and subsequent to their post and reflect on the value added to emergency medical education at three institutions. METHODS: We conducted an online survey study, examining quantitative outcomes and qualitative reflections, of emergency physicians who had previously undertaken a medical education registrar post...
May 22, 2018: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29788530/need-for-long-term-care-in-children-is-increasingly-caused-by-disorders-of-psychological-development-changes-in-the-care-causing-diagnoses-according-to-german-social-code-sgb-xi-between-2009-2014
#11
Julia Christiane Beck-Ripp, Holger Dressel
AIM OF THE STUDY: There is an ongoing discussion on the increasing number of children with mental and developmental disorders, with some even needing long-term care according to the German Social Code XI. This study was performed to identify the main diagnoses justifying such care in children and to analyse their prevalence over time. METHODS: The diagnoses justifying long-term care were evaluated using care assessments of Bavarian children and adolescents between 2009 to 2014 by the medical service of statutory health insurance...
May 22, 2018: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29788241/microsurgical-treatment-of-distal-anterior-cerebral-artery-aneurysms-3-dimensional-operative-video
#12
Vijay Agarwal, Daniel L Barrow
Selecting appropriate patient position for surgery must take into consideration a variety of factors. For an interhemispheric approach to distal anterior cerebral artery (DACA) aneurysms, the patient may be positioned with the head either horizontal or vertical with respect to the floor. We preferentially place the patient in the supine position with the shoulder elevated and the head turned parallel to the floor with the side of the approach down and the vertex tilted 45° up. In this way, gravity is utilized to allow the right frontal lobe to fall away from the falx, eliminating the need for retraction...
May 18, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29787900/associations-between-prenatal-and-childhood-pbde-exposure-and-early-adolescent-visual-verbal-and-working-memory
#13
Whitney J Cowell, Amy Margolis, Virginia A Rauh, Andreas Sjödin, Richard Jones, Ya Wang, Wanda Garcia, Frederica Perera, Shuang Wang, Julie B Herbstman
BACKGROUND: Prenatal and childhood exposure to polybrominated diphenyl ether (PBDE) flame retardants has been inversely associated with cognitive performance, however, few studies have measured PBDE concentrations in samples collected during both prenatal and postnatal periods. METHODS: We examined prenatal (cord) and childhood (ages 2, 3, 5, 7 and 9 years) plasma PBDE concentrations in relation to memory outcomes assessed between the ages of 9 and 14 years...
May 19, 2018: Environment International
https://www.readbyqxmd.com/read/29787722/programmed-dna-elimination-keeping-germline-genes-in-their-place
#14
Jeramiah J Smith
Each of our cells contains a full set of instructions needed to make an entire human: the genome. But a few special species buck this trend. A new study now identifies the first germline-specific gene in zebra finch, one of a small number of vertebrates that are known to undergo developmentally programmed DNA elimination.
May 21, 2018: Current Biology: CB
https://www.readbyqxmd.com/read/29786552/intestinal-organoids-for-modelling-intestinal-development-and-disease
#15
REVIEW
Kathryn L Fair, Jennifer Colquhoun, Nicholas R F Hannan
Gastrointestinal diseases are becoming increasingly prevalent in developed countries. Immortalized cells and animal models have delivered important but limited insight into the mechanisms that initiate and propagate these diseases. Human-specific models of intestinal development and disease are desperately needed that can recapitulate structure and function of the gut in vitro Advances in pluripotent stem cells and primary tissue culture techniques have made it possible to culture intestinal epithelial cells in three dimensions that self-assemble to form 'intestinal organoids'...
July 5, 2018: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/29784756/clinical-features-of-children-with-autism-who-passed-18-month-screening
#16
Roald A Øien, Synnve Schjølberg, Fred R Volkmar, Frederick Shic, Domenic V Cicchetti, Anders Nordahl-Hansen, Nina Stenberg, Mady Hornig, Alexandra Havdahl, Anne-Siri Øyen, Pamela Ventola, Ezra S Susser, Martin R Eisemann, Katarzyna Chawarska
OBJECTIVES: We compared sex-stratified developmental and temperamental profiles at 18 months in children screening negative for autism spectrum disorder (ASD) on the Modified Checklist for Autism in Toddlers (M-CHAT) but later receiving diagnoses of ASD (false-negative group) versus those without later ASD diagnoses (true-negative group). METHODS: We included 68 197 screen-negative cases from the Norwegian Mother and Child Cohort Study (49.1% girls). Children were screened by using the 6 critical items of the M-CHAT at 18 months...
May 21, 2018: Pediatrics
https://www.readbyqxmd.com/read/29783043/developmental-changes-in-the-perception-of-visuotactile-simultaneity
#17
Yi-Chuan Chen, Terri L Lewis, David I Shore, Charles Spence, Daphne Maurer
A simultaneity judgment (SJ) task was used to measure the developmental trajectory of visuotactile simultaneity perception in children (aged 7, 9, 11, and 13 years) and adults. Participants were presented with a visual flash in the center of a computer monitor and a tap on their right index finger (located 20° below the flash) with 13 possible stimulus onset asynchronies (SOAs). Participants reported whether the flash and tap were presented at the same time. Compared with the adult group, children aged 7 and 9 years made more simultaneous responses when the tap led by more than 300 ms and when the flash led by more than 200 ms, whereas they made fewer simultaneous responses at the 0 ms SOA...
May 18, 2018: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29782230/minimizing-restraint-and-seclusion-in-schools-a-response-to-beaudoin-and-moore
#18
Virginia L Walker, Sarah E Pinkelman
Increasing efforts have been made in the field of special education to identify positive, evidence-based practices (EBPs) to meet the needs of students who engage in problem behavior, with a major goal being to eliminate or limit the use of reactive measures such as restraint and seclusion ( Snell & Walker, 2014 ). Various stakeholders, including families and self-advocates, have voiced concerns about the dangers of restraint and seclusion and the lack of protection afforded to students who engage in severe problem behavior...
June 2018: Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/29782008/de-novo-generation-of-somatic-stem-cells-by-yap-taz
#19
Tito Panciera, Luca Azzolin, Daniele Di Biagio, Antonio Totaro, Michelangelo Cordenonsi, Stefano Piccolo
Here we present protocols to isolate primary differentiated cells and turn them into stem/progenitor cells (SCs) of the same lineage by transient expression of the transcription factor YAP. With this method, luminal differentiated (LD) cells of the mouse mammary gland are converted into cells that exhibit molecular and functional properties of mammary SCs. YAP also turns fully differentiated pancreatic exocrine cells into pancreatic duct-like progenitors. Similarly, to endogenous, natural SCs, YAP-induced stem-like cells ("ySCs") can be eventually expanded as organoid cultures long term in vitro, without further need of ectopic YAP/TAZ, as ySCs are endowed with a heritable self-renewing SC-like state...
May 7, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29781700/adapting-and-translating-the-mullen-scales-of-early-learning-for-the-south-african-context
#20
Juan Bornman, MaryAnn Romski, Kerstin Tonsing, Rose Sevcik, Robyn White, Andrea Barton-Hulsey, Refilwe Morwane
BACKGROUND:  South African speech-language therapists have identified the need for culturally valid and sensitive assessment tools that can accommodate multiple languages and cover a reasonable age range. The Mullen Scales of Early Learning (MSEL) extend from birth to 68 months, contain five separate subscales including receptive language, expressive language, gross motor, fine motor and visual reception scale, are straightforward to administer and have been successfully used in other African countries, such as Uganda...
March 8, 2018: South African Journal of Communication Disorders. die Suid-Afrikaanse Tydskrif Vir Kommunikasieafwykings
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