Brandilyn A Peters, David B Hanna, Yi Wang, Kathleen M Weber, Elizabeth Topper, Allison A Appleton, Anjali Sharma, Howard N Hodis, Nanette Santoro, Chantal Guillemette, Patrick Caron, Rob Knight, Robert D Burk, Robert C Kaplan, Qibin Qi
BACKGROUND: The cardio-protective roles of endogenous estrogens may be particularly important in women with HIV, who have reduced estrogen exposure and elevated cardiovascular disease risk. The gut microbiome metabolically interacts with sex hormones, but little is known regarding how such interplay may impact cardiovascular risk. METHODS: Among 197 post-menopausal women in the Women's Interagency HIV Study, we measured 15 sex hormones in serum and assessed the gut microbiome in stool...
August 29, 2023: Journal of Clinical Endocrinology and Metabolism