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https://www.readbyqxmd.com/read/29684842/shear-force-analysis-by-core-location-in-longissimus-steaks-from-nellore-cattle-using-hyperspectral-images-a-feasibility-study
#1
Juliana Monteiro Balage, José Manuel Amigo, Daniel Silva Antonelo, Madeline Rezende Mazon, Saulo da Luz E Silva
Industry requires non-destructive real-time methods for quality control of meat in order to improve production efficiency and meet consumer expectations. Near Infrared Hyperspectral Images were used for tenderness evaluation of Nellore beef and the construction of tenderness distribution maps. To investigate whether the selection of the region of interest (ROI) in the image at the exact location where the shear force core was collected improves tenderness prediction and classification models, 50 samples from Longissimus muscle were imaged (1000-2500 nm) and shear force were measured (Warner-Bratzler)...
April 12, 2018: Meat Science
https://www.readbyqxmd.com/read/29684658/caught-in-between-system-for-in-flow-inactivation-of-enzymes-as-an-intermediary-step-in-plug-and-play-microfluidic-platforms
#2
Ana C Fernandes, Benjamin Petersen, Lars Møller, Krist V Gernaey, Ulrich Krühne
The need for fast and comprehensive characterization of biocatalysts has pushed the development of new screening platforms based on microfluidics, capable of monitoring several parameters simultaneously, with new configurations of liquid handling, sample treatment and sensing. Modular microfluidics allows the integration of these newly developed approaches in a more flexible way towards increasing applicability of the microfluidic chips to different types of biocatalysts and reactions. A highly relevant operation in such a system is biocatalyst inactivation, which can enable the precise control of reaction time by avoiding the continuation of the reaction in another module or connecting tubes...
April 20, 2018: New Biotechnology
https://www.readbyqxmd.com/read/29684604/effect-of-antiaggregants-on-the-in-vitro-viability-cell-count-and-stability-of-abalone-haliotis-iris-haemocytes
#3
Roffi Grandiosa, Mai-Louise Bouwman, Tim Young, Fabrice Mérien, Andrea C Alfaro
The ability to successfully prepare and preserve haemocyte cells for microscopy and flow cytometry is critical for the investigation of animal immune systems. In this study, we observed the total cell count, in vitro viability and stability of New Zealand black-footed abalone (Haliotis iris) haemocytes with different antiaggregants and handling protocols. Haemocyte stability was evaluated by direct observation of haemocytes under the microscope and calculating the aggregation index. Haemocyte counts and viability were measured via flow cytometry and tested for the effect of different antiaggregants (Alsever's solution at three concentrations, and specialised blood collection tubes containing lithium heparin and K2 EDTA) at different temperatures and storage times...
April 20, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29684177/a-novel-measure-of-ewe-efficiency-for-breeding-and-benchmarking-purposes
#4
N McHugh, T Pabiou, K McDermott, E Wall, D P Berry
Ewe efficiency has traditionally been defined as the ratio of litter weight to ewe weight; given the statistical properties of ratio traits, an alternative strategy is proposed in the present study. The concept of using the deviation in performance of an animal from the population norm has grown in popularity as a measure of animal-level efficiency. The objective of the present study was to define novel measures of efficiency for sheep which considers the combined weight of a litter of lambs relative to the weight of their dam, and vice versa...
April 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29684096/toxic-effects-of-arsenic-trioxide-on-echinococcus-granulosus-protoscoleces-through-ros-production-and-ca2-er-stress-dependent-apoptosis
#5
Jiajie Li, Guangyao Tang, Wenjuan Qin, Rentan Yang, Rongji Ma, Bin Ma, Jianfeng Wei, Hailong Lv, Yufeng Jiang
Cystic echinococcosis is a severe parasitic disease that commonly affects the liver and causes abscesses or rupture into the surrounding tissues, leading to multiple complications, such as shock, severe abdominal pain, and post-treatment abscess recurrence. Currently, there are no efficient measures to prevent these complications. We previously confirmed that arsenic trioxide (As2O3) exhibited in vitro cytotoxicity against Echinococcus granulosus protoscoleces. In the present study, we aimed to explore the mechanism of As2O3-induced E...
April 19, 2018: Acta Biochimica et Biophysica Sinica
https://www.readbyqxmd.com/read/29683925/short-term-8-weeks-high-intensity-interval-training-in-diseased-cohorts
#6
James E M Blackwell, Brett Doleman, Philip J J Herrod, Samuel Ricketts, Bethan E Phillips, Jonathan N Lund, John P Williams
BACKGROUND & AIM: Exercise training regimes can lead to improvements in measures of cardiorespiratory fitness (CRF), improved general health, and reduced morbidity and overall mortality risk. High intensity interval training (HIIT) offers a time-efficient approach to improve CRF in healthy individuals, but the relative benefits of HIIT compared to traditional training methods are unknown in across different disease cohorts. METHODS: This systematic review and meta-analysis compares CRF gains in randomised controlled trials of short-term (<8 weeks) HIIT vs...
April 21, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29683909/acog-committee-opinion-no-734-the-role-of-transvaginal-ultrasonography-in-evaluating-the-endometrium-of-women-with-postmenopausal-bleeding
#7
(no author information available yet)
Cancer of the endometrium is the most common type of gynecologic cancer in the United States. Vaginal bleeding is the presenting sign in more than 90% of postmenopausal women with endometrial carcinoma. Clinical risk factors for endometrial cancer, including but not limited to age, obesity, use of unopposed estrogen, specific medical comorbidities (eg, polycystic ovary syndrome, type 2 diabetes mellitus, atypical glandular cells on screening cervical cytology), and family history of gynecologic malignancy also should be considered when evaluating postmenopausal bleeding...
May 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29683904/acog-committee-opinion-no-734-summary-the-role-of-transvaginal-ultrasonography-in-evaluating-the-endometrium-of-women-with-postmenopausal-bleeding
#8
(no author information available yet)
Cancer of the endometrium is the most common type of gynecologic cancer in the United States. Vaginal bleeding is the presenting sign in more than 90% of postmenopausal women with endometrial carcinoma. Clinical risk factors for endometrial cancer, including but not limited to age, obesity, use of unopposed estrogen, specific medical comorbidities (eg, polycystic ovary syndrome, type 2 diabetes mellitus, atypical glandular cells on screening cervical cytology), and family history of gynecologic malignancy also should be considered when evaluating postmenopausal bleeding...
May 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29683781/laboratory-evaluation-of-a-low-cost-real-time-aerosol-multi-sensor
#9
Robert J Vercellino, Darrah K Sleeth, Rodney G Handy, Kyeong T Min, Scott C Collingwood
Exposure to occupational aerosols are a known hazard in many industry sectors and can be a risk factor for several respiratory diseases. In this study, a laboratory evaluation of low-cost aerosol sensors, the Dylos DC1700 and a modified Dylos known as the Utah Modified Dylos Sensor (UMDS), was performed to assess the sensors' efficiency in sampling respirable and inhalable dust at high concentrations, which are most common in occupational settings. Dust concentrations were measured in a low-speed wind tunnel with 3 UMDSs, collocated with an aerosol spectrometer (Grimm 1...
April 23, 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29683558/simplified-hybrid-algorithms-for-pressure-wire-interrogation-exploiting-advantages-of-a-baseline-and-contrast-pd-pa-ratio-indexes-to-predict-stenosis-significance-insight-from-the-spare-multicenter-prospective-study
#10
E Cerrato, F Tomassini, P Salinas, M Pavani, F Conrotto, M Echavarria-Pinto, F Macaya, G Quadri, F D'Ascenzo, Alicia Quirós, F Varbella, J Escaned
BACKGROUND: Simplification of functional stenosis assessment with pressure guidewires may facilitate adoption of physiology-guided revascularization. An important step in this regard is the avoidance of hyperemic agents, required for fractional flow reserve (FFR) calculation. We evaluate the merits of a hybrid algorithms that combines the translesional pressure ratio (Pd/Pa) obtained at rest, after contrast medium injection (cFFR) and after adenosine administration (FFR). METHODS AND RESULTS: Eighty-six patients with 108 de novo intermediate coronary stenoses were included in this prospective, multicenter study...
April 23, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29683466/anatomy-of-triply-periodic-network-assemblies-characterizing-skeletal-and-inter-domain-surface-geometry-of-block-copolymer-gyroids
#11
Ishan Prasad, Hiroshi Jinnai, Rong-Ming Ho, Edwin L Thomas, Gregory M Grason
Triply-periodic networks (TPNs), like the well-known gyroid and diamond network phases, abound in soft matter assemblies, from block copolymers (BCPs), lyotropic liquid crystals and surfactants to functional architectures in biology. While TPNs are, in reality, volume-filling patterns of spatially-varying molecular composition, physical and structural models most often reduce their structure to lower-dimensional geometric objects: the 2D interfaces between chemical domains; and the 1D skeletons that thread through inter-connected, tubular domains...
April 23, 2018: Soft Matter
https://www.readbyqxmd.com/read/29683460/quantification-of-site-specific-protein-lysine-acetylation-and-succinylation-stoichiometry-using-data-independent-acquisition-mass-spectrometry
#12
Lei Wei, Jesse G Meyer, Birgit Schilling
Post-translational modification (PTM) of protein lysine residues by NƐ-acylation induces structural changes that can dynamically regulate protein functions, for example, by changing enzymatic activity or by mediating interactions. Precise quantification of site-specific protein acylation occupancy, or stoichiometry, is essential for understanding the functional consequences of both global low-level stoichiometry and individual high-level acylation stoichiometry of specific lysine residues. Other groups have reported measurement of lysine acetylation stoichiometry by comparing the ratio of peptide precursor isotopes from endogenous, natural abundance acylation and exogenous, heavy isotope-labeled acylation introduced after quantitative chemical acetylation of proteins using stable isotope-labeled acetic anhydride...
April 4, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29683371/hippocampal-related-memory-network-in-multiple-sclerosis-a-structural-connectivity-analysis
#13
Sara Llufriu, Maria A Rocca, Elisabetta Pagani, Gianna C Riccitelli, Elisabeth Solana, Bruno Colombo, Mariaemma Rodegher, Andrea Falini, Giancarlo Comi, Massimo Filippi
BACKGROUND: We used graph theoretical analysis to quantify structural connectivity of the hippocampal-related episodic memory network and its association with memory performance in multiple sclerosis (MS) patients. METHODS: Brain diffusion and T1-weighted sequences were obtained from 71 MS patients and 50 healthy controls (HCs). A total of 30 gray matter regions (selected a priori) were used as seeds to perform probabilistic tractography and create connectivity matrices...
April 1, 2018: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29683002/short-term-evaluation-of-hepatic-toxicity-of-titanium-dioxide-nanofiber-tdnf
#14
Leah K Bartel, Daniel A Hunter, Kayla B Anderson, W Yau, Ji Wu, Worlanyo E Gato
Various in vitro and in vivo studies have shown titanium dioxide nanoparticles (TDNPs) increase the production of reactive oxygen species and change the expression of genes and proteins involved in the inflammatory response and cell division. Although, the cytotoxicity of TDNPs has been shown to be largely dependent on the characteristics of the particles including shape and surface area. This present study investigates the effects of titanium dioxide nanofibers (TDNFs) with a diameter of 300-800 nm, on the histopathology of liver tissue, changes in feed efficiency and liver weights, changes in hepatic gene expression, and serum biochemical parameters in male Sprague-Dawley rats...
April 23, 2018: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29682876/soybean-lecithin-mediated-nanoporous-plga-microspheres-with-highly-entrapped-and-controlled-released-bmp-2-as-a-stem-cell-platform
#15
Daixu Wei, Ruirui Qiao, Jinwei Dao, Jing Su, Chengmin Jiang, Xichang Wang, Mingyuan Gao, Jian Zhong
Injectable polymer microsphere-based stem cell delivery systems have a severe problem that they do not offer a desirable environment for stem cell adhesion, proliferation, and differentiation because it is difficult to entrap a large number of hydrophilic functional protein molecules into the core of hydrophobic polymer microspheres. In this work, soybean lecithin (SL) is applied to entrap hydrophilic bone morphogenic protein-2 (BMP-2) into nanoporous poly(lactide-co-glycolide) (PLGA)-based microspheres by a two-step method: SL/BMP-2 complexes preparation and PLGA/SL/BMP-2 microsphere preparation...
April 22, 2018: Small
https://www.readbyqxmd.com/read/29682841/efficient-charge-transport-in-disordered-conjugated-polymer-microstructures
#16
REVIEW
Rodrigo Noriega
A new class of conjugated polymers with high charge mobilities exhibits the apparently conflicting morphological features of increased order at the molecular scale while lacking long-range order and crystallinity. To exploit their unique properties, mechanistic insights for charge transport events taking place from the molecular to the device scale must be uncovered. Thus, a central contributor to the continued progress in conjugated optoelectronic materials will be the development of advanced characterization tools, particularly those targeted to measuring the charge-transfer processes in heterogeneous, anisotropic, and hierarchically structured materials...
April 22, 2018: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/29682619/path-of-least-resistance-how-computerised-provider-order-entry-can-lead-to-and-reduce-wasteful-practices
#17
Joseph Choi, Cori Rebecca Atlin
Background: Computerised provider order entry (CPOE) is rapidly becoming the mainstay in clinical care and has the potential to improve provider efficiency and accuracy. However, this hinges on careful planning and implementation. Poorly planned CPOE order sets can lead to undetected errors and waste. In our emergency department (ED), lactate dehydrogenase (LDH) was bundled into various blood work panels but had little clinical value. Objectives: This quality improvement initiative aimed to reduce unnecessary LDH testing in the ED...
2018: BMJ Open Quality
https://www.readbyqxmd.com/read/29682533/bilateral-hip-arthroplasty-when-is-it-safe-to-operate-the-second-hip-a-systematic-review
#18
REVIEW
Meilyn Muskus, Jorge Rojas, Camilo Gutiérrez, Juan Guio, Guillermo Bonilla, Adolfo Llinás
Introduction: Patients with degenerative hip disease frequently present with bilateral involvement that requires surgical management. The main goal when treating these patients is to achieve the maximum efficiency without increasing risk of perioperative complications; therefore, the decision regarding the best moment to operate the second hip becomes relevant. Although studies have addressed this topic, whether a simultaneous or staged surgery should be performed remains controversial...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29682416/effects-of-fertilizations-on-soil-bacteria-and-fungi-communities-in-a-degraded-arid-steppe-revealed-by-high-through-put-sequencing
#19
Luhua Yao, Dangjun Wang, Lin Kang, Dengke Wang, Yong Zhang, Xiangyang Hou, Yanjun Guo
Background: Fertilization as one of the measures in restoring degraded soil qualities has been introduced on arid steppes in recent decades. However, the fertilization use efficiency on arid steppes varies greatly between steppe types and years, enhancing uncertainties and risks in introducing fertilizations on such natural system to restore degraded steppes. Methods: The experiment was a completely randomized design with five fertilization treatments, 0 (Control), 60 kg P ha-1 (P), 100 kg N ha-1 (N), 100 kg N ha-1 plus 60 kg P ha-1 (NP), and 4,000 kg sheep manure ha-1 (M, equaling 16...
2018: PeerJ
https://www.readbyqxmd.com/read/29681997/simultaneous-segmentation-of-leukocyte-and-erythrocyte-in-microscopic-images-using-a-marker-controlled-watershed-algorithm
#20
Huisi Miao, Changyan Xiao
The density or quantity of leukocytes and erythrocytes in a unit volume of blood, which can be automatically measured through a computer-based microscopic image analysis system, is frequently considered an indicator of diseases. The segmentation of blood cells, as a basis of quantitative statistics, plays an important role in the system. However, many conventional methods must firstly distinguish blood cells into two types (i.e., leukocyte and erythrocyte) and segment them in independent procedures. In this paper, we present a marker-controlled watershed algorithm for simultaneously extracting the two types of blood cells to simplify operations and reduce computing time...
2018: Computational and Mathematical Methods in Medicine
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