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https://www.readbyqxmd.com/read/28215008/the-greater-snow-goose-anser-caerulescens-atlanticus-managing-an-overabundant-population
#1
Josée Lefebvre, Gilles Gauthier, Jean-François Giroux, Austin Reed, Eric T Reed, Luc Bélanger
Between the early 1900s and the 1990s, the greater snow goose Anser caerulescens atlanticus population grew from 3000 individuals to more than 700 000. Because of concerns about Arctic degradation of natural habitats through overgrazing, a working group recommended the stabilization of the population. Declared overabundant in 1998, special management actions were then implemented in Canada and the United States. Meanwhile, a cost-benefit socioeconomic analysis was performed to set a target population size. Discussions aiming towards attaining a common vision were undertaken with stakeholders at multiple levels...
March 2017: Ambio
https://www.readbyqxmd.com/read/28214720/treatment-efficiency-and-economic-feasibility-of-biological-oxidation-membrane-filtration-and-separation-processes-and-advanced-oxidation-for-the-purification-and-valorization-of-olive-mill-wastewater
#2
L Ioannou-Ttofa, I Michael-Kordatou, S C Fattas, A Eusebio, B Ribeiro, M Rusan, A R B Amer, S Zuraiqi, M Waismand, C Linder, Z Wiesman, J Gilron, D Fatta-Kassinos
Olive mill wastewater (OMW) is a major waste stream resulting from numerous operations that occur during the production stages of olive oil. The resulting effluent contains various organic and inorganic contaminants and its environmental impact can be notable. The present work aims at investigating the efficiency of (i) jet-loop reactor with ultrafiltration (UF) membrane system (Jacto.MBR), (ii) solar photo-Fenton oxidation after coagulation/flocculation pre-treatment and (iii) integrated membrane filtration processes (i...
February 12, 2017: Water Research
https://www.readbyqxmd.com/read/28214230/synthesis-and-cytotoxic-activities-of-goniothalamins-and-derivatives
#3
Anja Weber, Katja Döhl, Julia Sachs, Anja C M Nordschild, Dennis Schröder, Andrea Kulik, Thomas Fischer, Lutz Schmitt, Nicole Teusch, Jörg Pietruszka
Substituted goniothalamins containing cyclopropane-groups were efficiently prepared in high yields and good selectivity. Antiproliferative activity was measured on three human cancer cell lines (A549, MCF-7, HBL-100), to show which of the structural elements of goniothalamins is mandatory for cytotoxicity. We found that the configuration of the stereogenic centre of the δ-lactone plays an important role for cytotoxicity. In our studies only (R)-configured goniothalamins showed antiproliferative activity, whereby (R)-configuration accords to natural goniothalamin (R)-1...
February 6, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28214051/effects-of-a-straw-phonation-protocol-on-acoustic-measures-of-an-satb-chorus-singing-two-contrasting-renaissance-works
#4
Jeremy N Manternach, Chad Clark, James F Daugherty
BACKGROUND: Researchers have found that semi-occluded vocal tract (SOVT) exercises may increase vocal economy by reducing phonation threshold pressure and effort while increasing or maintaining consistent acoustic output. This research has focused solely on individual singers. Much singing instruction, however, takes place in choral settings. Choral singers may use different resonance strategies or unconsciously adjust their singing based on the ability to hear their own sound in relation to others...
February 14, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28214046/productivity-growth-case-mix-and-optimal-size-of-hospitals-a-16-year-study-of-the-norwegian-hospital-sector
#5
Kjartan Sarheim Anthun, Sverre Andreas Campbell Kittelsen, Jon Magnussen
BACKGROUND AND OBJECTIVES: This paper analyses productivity growth in the Norwegian hospital sector over a period of 16 years, 1999-2014. This period was characterized by a large ownership reform with subsequent hospital reorganizations and mergers. We describe how technological change, technical productivity, scale efficiency and the estimated optimal size of hospitals have evolved during this period. MATERIAL AND METHODS: Hospital admissions were grouped into diagnosis-related groups using a fixed-grouper logic...
January 30, 2017: Health Policy
https://www.readbyqxmd.com/read/28214036/impact-of-filling-gas-on-subharmonic-emissions-of-phospholipid-ultrasound-contrast-agents
#6
Emma Kanbar, Damien Fouan, Charles A Sennoga, Alexander A Doinikov, Ayache Bouakaz
Subharmonic signals backscattered from gas-filled lipid-shelled microbubbles have generated significant research interest because they can improve the detection and sensitivity of contrast-enhanced ultrasound imaging. However, the emission of subharmonic signals is strongly characterized by a temporal dependence, the origins of which have not been sufficiently elucidated. The features that influence subharmonic emissions need to be identified not only to better develop next-generation microbubble contrast agents, but also to develop more efficient subharmonic imaging (SHI) modes and therapeutic strategies...
February 14, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28213988/-contribution-of-mindfulness-meditation-in-cognitive-behavioral-therapy-for-insomnia
#7
H Vanhuffel, M Rey, I Lambert, D Da Fonseca, F Bat-Pitault
INTRODUCTION: Insomnia is considered to be a serious public health issue affecting approximately 10% of adults. Chronic insomnia may increase the risk of health problem, psychological vulnerability and proneness to accidents. Cognitive behavioral therapy for insomnia (CBT-I) is recommended as the first line of treatment. Even though CBT-I is widely considered as an effective therapy, 20 to 30% of patients do not respond to this treatment. Mindfulness therapy, known to reduce rumination and stress, could be an interesting complement to enhance CBT-I...
February 14, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28213240/sensitive-and-precise-monitoring-of-phosphatidylethanol-in-human-blood-as-a-biomarker-for-alcohol-intake-by-ultrasound-assisted-dispersive-liquid-liquid-microextraction-combined-with-liquid-chromatography-tandem-mass-spectrometry
#8
Siming Wang, Ruiyue Yang, Fusui Ji, Hongxia Li, Jun Dong, Wenxiang Chen
Phosphatidylethanol (PEth) is a special phospholipid that is only formed in the presence of ethanol, and therefore, serves as a promising biomarker for alcohol intake. In this study, a simple, rapid and precise method based on LC-MS/MS combined with ultrasound-assisted dispersive liquid-liquid microextraction was developed and validated for the measurements of PEth (16:0/18:1, 16:0/18:2, 16:0/16:0, and 18:1/18:1) in human blood. The influences of several variables for sample extraction and MS detection were carefully investigated...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213235/preparation-and-characterization-of-a-packed-bead-immobilized-trypsin-reactor-integrated-into-a-pdms-microfluidic-chip-for-rapid-protein-digestion
#9
Adam Kecskemeti, Attila Gaspar
This paper demonstrates the design, efficiency and applicability of a simple, inexpensive and high sample throughput microchip immobilized enzymatic reactor (IMER) for rapid protein digestion. The IMER contains conventional silica particles with covalently immobilized trypsin packed inside of a poly(dimethylsiloxane) (PDMS) microchip channel (10mm×1mm×35µm). The microchip consists of 9 different channels, enabling 9 simultaneous protein digestions. Trypsin was covalently immobilized using carbodiimide activation, the ideal trypsin/silica particle ratio (i...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213111/childhood-maltreatment-is-associated-with-alteration-in-global-network-fiber-tract-architecture-independent-of-history-of-depression-and-anxiety
#10
Kyoko Ohashi, Carl M Anderson, Elizabeth A Bolger, Alaptagin Khan, Cynthia E McGreenery, Martin H Teicher
Childhood maltreatment is a major risk factor for psychopathology. It is also associated with alterations in the network architecture of the brain, which we hypothesized may play a significant role in the development of psychopathology. In this study, we analyzed the global network architecture of physically healthy unmedicated 18-25 year old subjects (n=262) using diffusion tensor imaging (DTI) MRI and tractography. Anatomical networks were constructed from fiber streams interconnecting 90 cortical or subcortical regions for subjects with no-to-low (n=122) versus moderate-to-high (n=140) exposure to maltreatment...
February 14, 2017: NeuroImage
https://www.readbyqxmd.com/read/28212963/clinician-reported-outcome-assessments-of-treatment-benefit-report-of-the-ispor-clinical-outcome-assessment-emerging-good-practices-task-force
#11
John H Powers, Donald L Patrick, Marc K Walton, Patrick Marquis, Stefan Cano, Jeremy Hobart, Maria Isaac, Spiros Vamvakas, Ashley Slagle, Elizabeth Molsen, Laurie B Burke
A clinician-reported outcome (ClinRO) assessment is a type of clinical outcome assessment (COA). ClinRO assessments, like all COAs (patient-reported, observer-reported, or performance outcome assessments), are used to 1) measure patients' health status and 2) define end points that can be interpreted as treatment benefits of medical interventions on how patients feel, function, or survive in clinical trials. Like other COAs, ClinRO assessments can be influenced by human choices, judgment, or motivation. A ClinRO assessment is conducted and reported by a trained health care professional and requires specialized professional training to evaluate the patient's health status...
January 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28212901/the-dissociation-of-the-hsp60-pro-caspase-3-complex-by-bis-pyridyl-oxadiazole-copper-complex-cubipyoxa-leads-to-cell-death-in-nci-h292-cancer-cells
#12
Celeste Caruso Bavisotto, Dragana Nikolic, Antonella Marino Gammazza, Rosario Barone, Filippa Lo Cascio, Emanuele Mocciaro, Giovanni Zummo, Everly Conway de Macario, Alberto Jl Macario, Francesco Cappello, Valentina Giacalone, Andrea Pace, Giampaolo Barone, Antonio Palumbo Piccionello, Claudia Campanella
Cell survival and proliferation are central to carcinogenesis, involving various mechanisms among which those that impede apoptosis are important. In this, the role of the molecular chaperone Hsp60 is unclear since it has been reported that it can be both, pro- or anti-apoptotic. A solution to this riddle is crucial to the development of anti-cancer therapies targeting Hsp60. We addressed this question using a tumor cell line, NCI-H292, and [Cu(3,5-bis(2'-pyridyl)-1,2,4-oxadiazole)2(H2O)2](ClO4)2, CubipyOXA, a copper-containing compound with cytotoxic properties...
February 10, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28212613/porphyromonas-gingivalis-can-invade-periodontal-ligament-stem-cells
#13
Chunling Pan, Junchao Liu, Hongyan Wang, Jia Song, Lisi Tan, Haijiao Zhao
BACKGROUND: Porphyromonas gingivalis is strongly associated with the development, progression, severity and recurrence of periodontitis. Periodontal ligament stem cells (PDLSCs) play an important role in the maintenance of periodontal tissue self-renewal and repair. The purpose of this study was to investigate the ability of P. gingivalis to infect PDLSCs using an in vitro monolayer model. METHODS: We separated and cultured primary PDLSCs using the tissue block with limiting dilution method...
February 17, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28212486/highly-efficient-and-anomalous-charge-transfer-in-van-der-waals-trilayer-semiconductors
#14
Frank Ceballos, Ming-Gang Ju, Samuel D Lane, Xiao Cheng Zeng, Hui Zhao
Two dimensional materials, such as graphene and monolayer transition metal dichalcogenides, allow the fabrication of multilayer structures without lattice matching restriction. A central issue in developing such artificial materials is to understand and control the interlayer electron transfer process, which plays a key role in harvesting their emergent properties. Recent photoluminescence and transient absorption measurements revealed that the electron transfer in hetero-bilayers occurs on ultrafast time scales...
February 17, 2017: Nano Letters
https://www.readbyqxmd.com/read/28212326/electrochemical-oxidation-of-l-selenomethionine-and-se-methylseleno-l-cysteine-at-a-thiol-compound-modified-gold-electrode-its-application-in-a-flow-through-voltammetric-sensor
#15
Lai-Hao Wang, Yu-Han Zhang
A flow-electrolytic cell that consists of a bare gold wire or of different thiol-compound-modified gold electrodes (such as 2,4-thiazolidinedione, 2-mercapto-5-thiazoline, 2-mercaptothiazoline, l-cysteine, thioglycolic acid) was designed to be used in a voltammetric detector to identify l-selenomethionine and Se-methylseleno-l-cysteine using high-performance liquid chromatography. Both l-selenomethionine and Se-methylseleno-l-cysteine are more efficiently electrochemically oxidized on a thiol/gold than on a bare gold electrode...
February 16, 2017: Sensors
https://www.readbyqxmd.com/read/28212252/health-literacy-in-orthopaedic-trauma-patients
#16
Filip Cosic, Lara Kimmel, Elton Edwards
OBJECTIVE: This study aimed to determine the level of health literacy in a postoperative orthopaedic trauma population and to evaluate the efficacy of a simple predischarge discussion strategy, targeted at improving health literacy. DESIGN: A pre-post intervention study was conducted from April 2014 to January 2015. SETTING: Academic Level 1 trauma center. PARTICIPANTS: One hundred ninety consecutive orthopaedic trauma patients with operatively managed lower limb fractures were recruited...
March 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28212035/ultrafast-time-resolved-x-ray-absorption-spectroscopy-of-ferrioxalate-photolysis-with-a-laser-plasma-x-ray-source-and-microcalorimeter-array
#17
Galen C O'Neil, Luis Miaja-Avila, Young Il Joe, Bradley K Alpert, Mahalingam Balasubramanian, Dodderi M Sagar, William Bertrand Doriese, Joseph W Fowler, Wilfred K Fullagar, Ning Chen, Gene C Hilton, Ralph Jimenez, Bruce Ravel, Carl D Reintsema, Dan R Schmidt, Kevin L Silverman, Daniel S Swetz, Jens Uhlig, Joel N Ullom
The detailed pathways of photoactivity on ultrafast timescales are a topic of contemporary interest. Using a tabletop apparatus based upon a laser plasma x-ray source and an array of cryogenic microcalorimeter x-ray detectors, we have measured a transient x-ray absorption spectrum during the ferrioxalate photoreduction reaction. With these high efficiency detectors we observe the Fe K edge move to lower energies, and the amplitude of the extended x-ray absorption fine structure reduce, consistent with a photoreduction mechanism in which electron transfer precedes disassociation...
February 17, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28211968/verse-guided-parallel-rf-excitations-using-dynamic-field-correction
#18
Mustafa Çavuşoğlu, Ronald Mooiweer, Klaas P Pruessmann, Shaihan J Malik
In parallel RF pulse design, peak RF magnitudes and specific absorption rate levels are critical concerns in the hardware and safety limits. The variable rate selective excitation (VERSE) method is an efficient technique to limit the peak RF power by applying a local-only RF and gradient waveform reshaping while retaining the on-resonance profile. The accuracy of the excitation performed by the VERSEd RF and gradient waveforms strictly depends on the performance of the employed hardware. Any deviation from the nominal gradient fields as a result of frequency dependent system imperfections violates the VERSE condition similarly to off-resonance effects, leading to significant excitation errors and the RF pulse not converging to the targeted peak RF power...
February 17, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28211943/a-general-statistical-framework-for-subgroup-identification-and-comparative-treatment-scoring
#19
Shuai Chen, Lu Tian, Tianxi Cai, Menggang Yu
Many statistical methods have recently been developed for identifying subgroups of patients who may benefit from different available treatments. Compared with the traditional outcome-modeling approaches, these methods focus on modeling interactions between the treatments and covariates while by-pass or minimize modeling the main effects of covariates because the subgroup identification only depends on the sign of the interaction. However, these methods are scattered and often narrow in scope. In this article, we propose a general framework, by weighting and A-learning, for subgroup identification in both randomized clinical trials and observational studies...
February 17, 2017: Biometrics
https://www.readbyqxmd.com/read/28211919/high-performance-regular-perovskite-solar-cells-employing-low-cost-poly-ethylenedioxythiophene-as-a-hole-transporting-material
#20
Xiaoqing Jiang, Ze Yu, Yuchen Zhang, Jianbo Lai, Jiajia Li, Gagik G Gurzadyan, Xichuan Yang, Licheng Sun
Herein, we successfully applied a facile in-situ solid-state synthesis of conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) as a HTM, directly on top of the perovskite layer, in conventional mesoscopic perovskite solar cells (PSCs) (n-i-p structure). The fabrication of the PEDOT film only involved a very simple in-situ solid-state polymerisation step from a monomer 2,5-dibromo-3,4-ethylenedioxythiophene (DBEDOT) made from a commercially available and cheap starting material. The ultraviolet photoelectron spectroscopy (UPS) demonstrated that the as-prepared PEDOT film possesses the highest occupied molecular orbital (HOMO) energy level of -5...
February 13, 2017: Scientific Reports
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