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https://www.readbyqxmd.com/read/28229552/h-pylori-as-a-predictor-of-marginal-ulceration-a-nationwide-analysis
#1
Allison R Schulman, Marwan S Abougergi, Christopher C Thompson
OBJECTIVE: Helicobacter pylori has been implicated as a risk factor for development of marginal ulceration following gastric bypass, although studies have been small and yielded conflicting results. This study sought to determine the relationship between H. pylori infection and development of marginal ulceration following bariatric surgery in a nationwide analysis. METHODS: This was a retrospective cohort study using the 2012 Nationwide Inpatient Sample (NIS) database...
March 2017: Obesity
https://www.readbyqxmd.com/read/28225738/pneumatosis-intestinalis-predictive-evaluation-study-a-multicenter-epidemiologic-study-of-the-american-association-for-the-surgery-of-trauma
#2
Paula Ferrada, Rachael Callcut, Graciela Bauza, Karen R O'Bosky, Xian Luo-Owen, Nicky J Mansfield, Kenji Inaba, Jason Pasley, Nikolay Bugaev, Bruno Pereira, Forrest O Moore, Jinfeng Han, Amelia Pasley, Joseph DuBose
BACKGROUND: Our group has previously published a retrospective review defining variables predictive of transmural bowel ischemia in the setting of pneumatosis intestinalis (PI). We hypothesize this prospective study will confirm the findings of the retrospective review, enhancing legitimacy to the predictive factors for pathologic PI previously highlighted. METHODS: Data were collected using the Research Electronic Data Capture. Forward logistic regression was utilized to identify independent predictors for pathologic PI...
March 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28222801/a-new-method-for-treating-fecal-incontinence-by-implanting-stem-cells-derived-from-human-adipose-tissue-preliminary-findings-of-a-randomized-double-blind-clinical-trial
#3
Arash Sarveazad, Graham L Newstead, Rezvan Mirzaei, Mohammad Taghi Joghataei, Mehrdad Bakhtiari, Asrin Babahajian, Bahar Mahjoubi
BACKGROUND: Anal sphincter defects are a major cause of fecal incontinence causing negative effects on daily life, social interactions, and mental health. Because human adipose-derived stromal/stem cells (hADSCs) are easier and safer to access, secrete high levels of growth factor, and have the potential to differentiate into muscle cells, we investigated the ability of hADSCs to improve anal sphincter incontinence. METHODS: The present randomized double-blind clinical trial was performed on patients with sphincter defects...
February 21, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28218495/design-and-evaluation-of-a-variable-stiffness-manual-operating-platform-for-laparoendoscopic-single-site-surgery-less
#4
Jinhua Li, Xuejie Li, Jianchen Wang, Yuan Xing, Shuxin Wang, Xiangyun Ren
BACKGROUND: Most of the existing robotic platforms for LESS have workspace and load capacity weaknesses, because of the limitation of one single incision. We have developed a LESS manual operating platform of which the stiffness of the insertion tube is controllable. METHODS: The system included two dexterous tool manipulators, a stereo-vision module and a variable stiffness insertion tube (VSIT), which was designed using phase-change material (mixed indium, gallium and stannum)...
February 20, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/28210563/neoadjuvant-therapy-for-treatment-of-breast-cancer-the-way-forward-or-simply-a-convenient-option-for-patients
#5
COMMENT
Abhishek Chatterjee, John K Erban
The complexity of managing early stage breast cancer is well known. Optimal treatment is increasingly multidisciplinary and in the modern era informed by sophisticated molecular tools to help select and guide therapy. Major phase III trials have determined that the order of systemic therapy relative to surgery does not influence important endpoints such as event free survival and overall survival (OS), but questions remain as to how best to utilize these most essential services. For example, there is still uncertainty regarding the ideal timing, intensity, and duration of proposed therapy...
February 2017: Gland Surgery
https://www.readbyqxmd.com/read/28207462/what-are-the-contributing-factors-for-postsurgical-relapse-after-two-jaw-surgery-in-patients-with-cleft-lip-and-palate
#6
Yoon-Hee Park, Ji-Hee Seo, Il-Hyung Yang, Jin-Young Choi, Jong-Ho Lee, Myung-Jin Kim, Seung-Hak Baek
The purpose of this study was to investigate the amount and pattern of postsurgical relapse after 2-jaw surgery in cleft lip and palate patients in terms of the sagittal and vertical aspects. The samples consisted of 21 adult patients who had the similar initial skeletodental pattern before surgery and underwent 2-jaw surgery. They were divided into high relapse (n = 11) and low relapse groups (n = 10) (criteria, 30% forward relapse of the B point). After the cephalometric variables of cephalograms taken at 1 month before surgery (T0), immediately after surgery (T1), and at least 1 year after surgery (T2) were measured, the Wilcoxon test, Mann-Whitney U test, and Pearson correlation test were performed for statistical analysis...
February 15, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28205075/hamstring-autograft-versus-patellar-tendon-autograft-for-acl-reconstruction-is-there-a-difference-in-graft-failure-rate-a-meta-analysis-of-47-613-patients
#7
Brian T Samuelsen, Kate E Webster, Nick R Johnson, Timothy E Hewett, Aaron J Krych
BACKGROUND: Bone-patellar tendon-bone (bone-tendon-bone) and four-strand hamstring tendon grafts (hamstring) are the most commonly utilized autografts for primary anterior cruciate ligament (ACL) reconstruction. Existing clinical trials, registry studies, and meta-analyses offer conflicting opinions regarding the most favorable graft choice. QUESTIONS/PURPOSES: Which graft type for ACL reconstruction (bone-tendon-bone or hamstring) has a higher risk of (1) graft rupture and/or (2) graft laxity? METHODS: We performed a meta-analysis of randomized controlled trials (RCTs), prospective cohort studies, and high-quality national registry studies to compare the outcomes of primary ACL reconstruction with bone-tendon-bone autograft or hamstring autograft...
February 15, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28203455/risk-balancing-of-cold-ischemic-time-against-night-shift-surgery-possibly-reduces-rates-of-reoperation-and-perioperative-graft-loss
#8
Nikos Emmanouilidis, Julius Boeckler, Bastian P Ringe, Alexander Kaltenborn, Frank Lehner, Hans Friedrich Koch, Jürgen Klempnauer, Harald Schrem
Background. This retrospective cohort study evaluates the advantages of risk balancing between prolonged cold ischemic time (CIT) and late night surgery. Methods. 1262 deceased donor kidney transplantations were analyzed. Multivariable regression was used to determine odds ratios (ORs) for reoperation, graft loss, delayed graft function (DGF), and discharge on dialysis. CIT was categorized according to a forward stepwise pattern ≤1h/>1h, ≤2h/>2h, ≤3h/>3h,…, ≤nh/>nh. ORs for DGF were plotted against CIT and a nonlinear regression function with best R(2) was identified...
2017: Journal of Transplantation
https://www.readbyqxmd.com/read/28196114/retinopathy-of-prematurity-a-comprehensive-risk-analysis-for-prevention-and-prediction-of-disease
#9
Leah A Owen, Margaux A Morrison, Robert O Hoffman, Bradley A Yoder, Margaret M DeAngelis
BACKGROUND: Retinopathy of prematurity (ROP) is a blinding morbidity of preterm infants. Our current screening criteria have remained unchanged since their inception and lack the ability to identify those at greatest risk. OBJECTIVES: We sought to comprehensively analyze numerous proposed maternal, infant, and environmental ROP risk variables in a robustly phenotyped population using logistic regression to determine the most predictive model for ROP development and severity...
2017: PloS One
https://www.readbyqxmd.com/read/28193299/otolaryngology-outreach-to-komfo-anokye-teaching-hospital-a-medical-and-educational-partnership
#10
B Waller, R Larsen-Reindorf, M Duah, J Opoku-Buabeng, B M Edwards, D Brown, J Moyer, M Prince, G J Basura
BACKGROUND: Medical and educational partnerships between high- and low-resourced countries provide opportunities to have a long-term meaningful impact on medical training and healthcare delivery. METHODS: An otolaryngology partnership between Komfo Anokye Teaching Hospital in Kumasi, Ghana, and the University of Michigan Department of Otolaryngology/Head and Neck Surgery has been undertaken to enhance healthcare delivery at both institutions. RESULTS: A temporal bone dissection laboratory, with the equipment to perform dedicated otological surgery, and academic platforms for clinical and medical education and residency training have been established...
February 14, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28184237/laparoscopic-vs-open-surgery-for-the-treatment-of-iatrogenic-colonoscopic-perforations-a-systematic-review-and-meta-analysis
#11
REVIEW
Aleix Martínez-Pérez, Nicola de'Angelis, Francesco Brunetti, Yann Le Baleur, Carmen Payá-Llorente, Riccardo Memeo, Federica Gaiani, Marco Manfredi, Paschalis Gavriilidis, Giorgio Nervi, Federico Coccolini, Aurelien Amiot, Iradj Sobhani, Fausto Catena, Gian Luigi de'Angelis
AIMS: Iatrogenic colonoscopy perforations (ICP) are a rare but severe complication of diagnostic and therapeutic colonoscopies. The present systematic review and meta-analysis aims to investigate the operative and post-operative outcomes of laparoscopy vs. open surgery performed for the management of ICP. METHODS: A literature search was carried out on Medline, EMBASE, and Scopus databases from January 1990 to June 2016. Clinical studies comparing the outcomes of laparoscopic and open surgical procedures for the treatment for ICP were retrieved and analyzed...
2017: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/28180987/preoperative-high-maximum-standardized-uptake-value-in-association-with-glucose-transporter-1-predicts-poor-prognosis-in-pancreatic-cancer
#12
Akira Chikamoto, Risa Inoue, Yoshiaki Komohara, Kentaro Sakamaki, Daisuke Hashimoto, Shinya Shiraishi, Hiroshi Takamori, Yo-Ichi Yamashita, Naoya Yoshida, Takeharu Yamanaka, Yasuyuki Yamashita, Hideo Baba
BACKGROUND: The diagnosis of malignant diseases worldwide has been determined using (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET). Glucose transporter type 1 (Glut-1) is a key protein associated with the accumulation of FDG in cancer cells. This study evaluated the relationship between Glut-1 expression and FDG accumulation to determine the usefulness of FDG-PET for prediction of long-term outcomes of pancreatic cancer. METHODS: The expression of Glut-1 was immunohistochemically examined in 138 surgically resected pancreatic cancer specimens...
February 8, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28179749/danish-translation-and-linguistic-validation-of-the-body-q-a-description-of-the-process
#13
Lotte Poulsen, Michael Rose, Anne Klassen, Kirsten K Roessler, Jens Ahm Sørensen
BACKGROUND: Patient-reported outcome (PRO) instruments are increasingly being included in research and clinical practice to assess the patient point of view. Bariatric and body contouring surgery has the potential to improve or restore a patient's body image and health-related quality of life (HR-QOL). A new PRO instrument, called the BODY-Q, has recently been developed specifically for this patient group. The aim of the current study was to translate and perform a linguistic validation of the BODY-Q for use in Danish bariatric and body contouring patients...
2017: European Journal of Plastic Surgery
https://www.readbyqxmd.com/read/28178956/translation-and-validation-of-the-12-item-oxford-knee-score-for-use-in-finland
#14
Aleksi Reito, Anni Järvistö, Esa Jämsen, Eerik Skyttä, Ville Remes, Heini Huhtala, Mika Niemeläinen, Antti Eskelinen
BACKGROUND: The focus in the reporting of results after total knee replacement (TKR) has changed from surgeon/radiologist-based scores to patient-reported outcome measures (PROMs). The questionnaires used in subjective outcome are often originally published in English and need to be validated in different languages. The aim of our study was to investigate the feasibility, validity, reliability, and responsiveness of the Finnish language version of the Oxford Knee Score (OKS-S) questionnaire...
February 8, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28141953/interposition-dermal-matrix-xenografts
#15
Julie A Neumann, Miltiadis H Zgonis, Kathleen D Rickert, Kendall E Bradley, Thomas J Kremen, Blake R Boggess, Alison P Toth
BACKGROUND: Management of massive rotator cuff tears in shoulders without glenohumeral arthritis remains problematic for surgeons. Repairs of massive rotator cuff tears have failure rates of 20% to 94% at 1 to 2 years postoperatively as demonstrated with arthrography, ultrasound, and magnetic resonance imaging. Additionally, inconsistent outcomes have been reported with debridement alone of massive rotator cuff tears, and limitations have been seen with other current methods of operative intervention, including arthroplasty and tendon transfers...
January 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28139385/nonoperative-management-versus-reverse-shoulder-arthroplasty-for-treatment-of-3-and-4-part-proximal-humeral-fractures-in-older-adults
#16
Troy A Roberson, Charles M Granade, Quinn Hunt, James T Griscom, Kyle J Adams, Amit M Momaya, Adam Kwapisz, Michael J Kissenberth, Stefan J Tolan, Richard J Hawkins, John M Tokish
BACKGROUND: The treatment of 3- and 4-part proximal humeral fractures in the older adult is controversial. No study has directly compared reverse shoulder arthroplasty (RSA) with nonoperative treatment for these fractures. The purpose of this study was to compare clinical and patient-reported outcomes between RSA and nonoperative treatment groups. METHODS: A retrospective review was performed on all 3- and 4-part proximal humeral fractures treated with either RSA or nonoperative treatment with minimum 1-year follow-up...
January 27, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28133947/serious-gaming-for-orthotopic-liver-transplant-anesthesiology-a-randomized-control-trial
#17
Daniel Katz, Jeron Zerillo, Sang Kim, Bryan Hill, Ryan Wang, Andrew Goldberg, Samuel DeMaria
: Anesthetic management of orthotopic liver transplantation (OLT) is complex. Given the unequal distributions of liver transplant surgeries performed at different centers, anesthesiology providers receive relatively uneven OLT training and exposure. One well-suited modality for OLT training is the "serious game", an interactive application created for the purpose of imparting knowledge or skills, while leveraging the self-motivating elements of video games. We therefore developed a serious game designed to teach best practices for the anesthetic management of a standard OLT and determined if the game would improve resident performance in a simulated OLT...
January 30, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28131695/speed-of-recovery-after-arthroscopic-rotator-cuff-repair
#18
Jennifer Kurowicki, Derek D Berglund, Enesi Momoh, Shanell Disla, Brandon Horn, M Russell Giveans, Jonathan C Levy
BACKGROUND: The purpose of this study was to delineate the time taken to achieve maximum improvement (plateau of recovery) and the degree of recovery observed at various time points (speed of recovery) for pain and function after arthroscopic rotator cuff repair. METHODS: An institutional shoulder surgery registry query identified 627 patients who underwent arthroscopic rotator cuff repair between 2006 and 2015. Measured range of motion, patient satisfaction, and patient-reported outcome measures were analyzed for preoperative, 3-month, 6-month, 1-year, and 2-year intervals...
January 26, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28125675/a-special-tear-pattern-of-anterior-horn-of-the-lateral-meniscus-macerated-tear
#19
Jiapeng Zheng, Wenliang Zhai, Qiang Li, Qianxin Jia, Dasheng Lin
BACKGROUND: We describe a special, interesting phenomenon found in the anterior horn of the lateral meniscus (AHLM): most tear patterns in the AHLM are distinctive, with loose fibers in injured region and circumferential fiber bundles were separated. We name it as macerated tear. The goal of this study was to bring forward a new type of meniscal tear in the AHLM and investigate its clinical value. MATERIALS AND METHODS: AHLM tears underwent arthroscopic surgery from January 2012 to December 2014 were included...
2017: PloS One
https://www.readbyqxmd.com/read/28121030/the-gut-microbiome-and-the-mechanism-of-surgical-infection
#20
REVIEW
J C Alverdy, S K Hyoju, M Weigerinck, J A Gilbert
BACKGROUND: Since the very early days of surgical practice, surgeons have recognized the importance of considering that intestinal microbes might have a profound influence on recovery from surgical diseases such as appendicitis and peritonitis. Although the pathogenesis of surgical diseases such as cholelithiasis, diverticulosis, peptic ulcer disease and cancer have been viewed as disorders of host biology, they are emerging as diseases highly influenced by their surrounding microbiota...
January 2017: British Journal of Surgery
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