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Dental Caries

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https://www.readbyqxmd.com/read/28335307/zinc-oxide-nanorods-decorated-graphene-nanoplatelets-a-promising-antimicrobial-agent-against-the-cariogenic-bacterium-streptococcus-mutans
#1
Elena Zanni, Chandrakanth Reddy Chandraiahgari, Giovanni De Bellis, Maria Rita Montereali, Giovanna Armiento, Paolo Ballirano, Antonella Polimeni, Maria Sabrina Sarto, Daniela Uccelletti
Nanomaterials are revolutionizing the field of medicine to improve the quality of life due to the myriad of applications stemming from their unique properties, including the antimicrobial activity against pathogens. In this study, the antimicrobial and antibiofilm properties of a novel nanomaterial composed by zinc oxide nanorods-decorated graphene nanoplatelets (ZNGs) are investigated. ZNGs were produced by hydrothermal method and characterized through field-emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD) techniques...
September 29, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28335264/antimicrobial-properties-of-biofunctionalized-silver-nanoparticles-on-clinical-isolates-of-streptococcus-mutans-and-its-serotypes
#2
Ángel Manuel Martínez-Robles, Juan Pablo Loyola-Rodríguez, Norma Verónica Zavala-Alonso, Rita Elizabeth Martinez-Martinez, Facundo Ruiz, René Homero Lara-Castro, Alejandro Donohué-Cornejo, Simón Yobanny Reyes-López, León Francisco Espinosa-Cristóbal
(1) Background: Streptococcus mutans (S. mutans) is the principal pathogen involved in the formation of dental caries. Other systemic diseases have also been associated with specific S. mutans serotypes (c, e, f, and k). Silver nanoparticles (SNP) have been demonstrated to have good antibacterial effects against S. mutans; therefore, limited studies have evaluated the antimicrobial activity of biofunctionalized SNP on S. mutans serotypes. The purpose of this work was to prepare and characterize coated SNP using two different organic components and to evaluate the antimicrobial activity of SNP in clinical isolates of S...
July 22, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28331230/dentin-sialoprotein-facilitates-dental-mesenchymal-cell-differentiation-and-dentin-formation
#3
Wentong Li, Lei Chen, Zhuo Chen, Lian Wu, Junsheng Feng, Feng Wang, Lisa Shoff, Xin Li, Kevin J Donly, Mary MacDougall, Shuo Chen
Dentin sialoprotein (DSP) is a dentin extracellular matrix protein. It is involved in dental mesenchymal cell lineages and dentin formation through regulation of its target gene expression. DSP mutations cause dentin genetic diseases. However, mechanisms of DSP in controlling dental mesenchymal cell differentiation are unknown. Using DSP as bait, we screened a protein library from mouse odontoblastic cells and found that DSP is a ligand and binds to cell surface receptor, occludin. Further study identified that the C-terminal DSP domain(aa 363-458) interacts with the occludin extracellular loop 2(aa 194-241)...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28327266/milk-sweetened-with-xylitol-a-proof-of-principle-caries-prevention-randomized-clinical-trial
#4
Donald L Chi, Graciela Zegarra, Elsa C Vasquez Huerta, Jorge L Castillo, Peter Milgrom, Marilyn C Roberts, Ailin R Cabrera-Matta, Ana P Merino
PURPOSE: To evaluate the efficacy of xylitol-sweetened milk as a caries-preventive strategy. METHODS: In this nine-month prospective proof-of-principle trial, Peruvian schoolchildren were randomized to one of five different milk groups: (1) eight g of xylitol per 200 mL milk once per day; (2) four g of xylitol per 100 mL milk twice per day; (3) eight g of sorbitol per 200 mL milk once per day; (4) four g of sorbitol per 100 mL milk twice per day; or (5) eight g of sucrose per 200 mL milk once per day...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28327265/association-between-body-mass-index-and-caries-experience-in-brazilian-children-and-adolescents
#5
Raquel Assed Bezerra da Silva, Driely Barreiros, Sara Oliveira, Lea Assed Bezerra da Silva, Paulo Nelson-Filho, Erika Calvano Küchler
PURPOSE: The purpose of this study was to evaluate the association between caries and body mass index (BMI) deviations in Brazilian schoolchildren and adolescents. METHODS: A total of 237 three- to 15-year-old children, all undergoing treatment in a university pediatric dental clinic, was evaluated. Caretakers answered a questionnaire on sociodemographic, ethnicity, oral hygiene, and dietary information. The children's height was measured in centimeters, the weight in kilograms, and BMIs were calculated...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28327264/association-of-candida-species-isolated-from-the-dental-plaque-of-hiv-infected-children-and-prevalence-of-early-carious-lesions
#6
Cristiana Aroeira Rosa Oliveira, Senda Charone, Rosangela Maria de Araújo Soares, Maristela Barbosa Portela, Gloria Fernanda Barbosa de Aráujo Castro
PURPOSE: The purposes of this study were to: (1) quantify and identify Candida species (spp.) in the dental plaque of children infected with the human immunodeficiency virus (HIV) and compare with noninfected children; and (2) determine the association of Candida spp. with the presence of caries. METHODS: Seventy HIV-infected and 55 non-HIV-infected three- to 12-year-old children were examined to determine caries prevalence. After a visual inspection, supragingival plaque was collected from the cervical region using standard dental curettes...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28327260/vitamin-d-and-dental-caries-in-primary-dentition
#7
Ana Lucia Seminario, Elizabet Velan
Traditionally classified as a vitamin, vitamin D represents a group of fat-soluble secosteroids with D2 (ergocalciferol) and D3 (cholecalciferol) being the most relevant of the group. The importance of this prohormone exceeds its known ability to maintain intra- and extracellular calcium and phosphate concentrations, thereby preserving essential metabolic functions such as the promotion of mineralization and maintenance and remodeling of the bone. Current observational research recognizes the potential antiproliferative, prodifferentiative, and immunomodulatory effects of vitamin D and its metabolites in the human body...
September 15, 2016: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28327128/the-investigation-of-helicobacter-pylori-in-the-dental-biofilm-and-saliva-samples-of-children-with-dyspeptic-complaints
#8
Damla Aksit Bıcak, Serap Akyuz, Binnur Kıratlı, Merve Usta, Nafiye Urganci, Burcin Alev, Aysen Yarat, Fikrettin Sahin
BACKGROUND: The oral cavity can be an extra-gastric reservoir for Helicobacter pylori (H.pylori). This can play a role in the pathogenesis of halitosis, glossitis, recurrent aphthous stomatitis, and dental caries. The present study was conducted to detect the presence of H.pylori within the dental biofilm and in saliva samples collected from children suffering from dyspepsia and children without any gastrointestinal complaints. Associations with gastric infection, halitosis, and some oral parameters were also evaluated...
March 21, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28327110/an-assessment-of-the-impacts-of-child-oral-health-in-indonesia-and-associations-with-self-esteem-school-performance-and-perceived-employability
#9
Diah Ayu Maharani, Melissa Adiatman, Anton Rahardjo, Girvan Burnside, Cynthia Pine
BACKGROUND: Previous surveys have indicated that a majority of Indonesian children have poor oral health. However, little detailed information is available on underlying causation and none that examine impacts of oral health on child self-esteem, school performance and perceived employability. The aim of this study was to determine levels of child oral health in primary school children in Indonesia, the prevalence of key causal factors; and, to determine relationships between oral health, self-esteem and school academic performance...
March 21, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28326737/-research-progress-on-a-nanodrug-delivery-system-for-prevention-and-control-of-dental-caries-and-periodontal-diseases
#10
Jiang Yaling, Feng Mingye, Cheng Lei
Dental caries and periodontal diseases are common chronic infectious diseases that cause serious damage to oral health. Bacteria is the primary factor leading to such conditions. As a dental plaque control method, chemotherapeutic agents face serious challenges in dental care because of the specific physiological and anatomical characteristics of the oral cavity. Nanodrug delivery system is a series of new drug delivery systems at nanoscale, and it can target cells, promote sustainedrelease effects, and enhance biodegradation...
February 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28326721/-difficulty-influence-factors-of-dental-caries-clinical-treatment
#11
Zhou Xuedong, Ling Junqi, Liang Jingping, Li Jiyao, Cheng Lei, Yu Qing, Niu Yumei, Guo Bin, Chen Hui
Dental caries is a major disease that threaten human's oral healthy severely with the characteristics of high incidence, low rate of treatment and high rate of retreatment. At present, restorative treatment remains the main method for caries treatment. With the development of the Minimally Invasive Cosmetic Dentistry (MICD), reasonable application of various treatment technologies, maximum preservation of tooth tissues and realizing the maximization of treatment effects become problems that call for immediate solution in dental clinics...
February 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28326712/-strategy-and-practice-of-the-healthy-cosmetic-management-for-patients-with-high-dental-caries-susceptibility
#12
Liu Tao, Cheng Li, Yang Hui, Wang Huning, Fang Hongzhi, Hu Tao
A new clinic conception, healthy cosmetic management (HCM), was innovated introduced into diagnose and treatment of patients with high caries risk. The priority of HCM should be given to aesthetic restoration of teeth, taking consideration of the conserving of tissue and pulp of teeth and the balance between health and aesthetics, which may reach to the goal of the individual clinic treatment. HCM includes five steps: 1) caries risk assessment; 2) detection of initial caries; 3) digital aesthetic design; 4) minimally invasive therapy; 5) behavior management of caries and doctor-patient communication pattern...
October 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28326155/dental-plaque-microbial-profiles-of-children-from-khartoum-sudan-with-congenital-heart-defects
#13
Hiba Mohamed Ali, Ellen Berggreen, Daniel Nguyen, Raouf Wahab Ali, Thomas E Van Dyke, Hatice Hasturk, Manal Mustafa
Few studies have focused on the bacterial species associated with the deterioration of the dental and gingival health of children with congenital heart defects (CHD). The aims of this study were (1) to examine the dental plaque of children with CHD in order to quantify bacterial load and altered bacterial composition compared with children without CHD; and (2) to investigate the correlation between the level of caries and gingivitis and dental biofilm bacteria among those children. In this cross-sectional study, participants were children (3-12 years) recruited in Khartoum State, Sudan...
2017: Journal of Oral Microbiology
https://www.readbyqxmd.com/read/28322358/inhibitory-effects-of-nitrite-on-acid-%C3%A2-production-in-dental-plaque-in-children
#14
Yuji Yamamoto, Jumpei Washio, Koichi Shimizu, Koei Igarashi, Nobuhiro Takahashi
PURPOSE: To assess the inhibitory effects of nitrite on plaque acidogenicity and its relationship with caries experience. MATERIALS AND METHODS: Plaque (2 μl) was collected from 76 children (age 5.8 = 2.6 years, dmft = 2.9 = 3.5, DMTF = 0.6 = 1.4) and mixed with nitrite solution (final concentration = 0.63 mM) or distilled water (control). The initial pH (pH-0) of each sample was measured using a portable pH meter. The samples were incubated for 10 min, then their pH (pH-1) was measured again...
March 20, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28322357/assessment-of-dental-caries-experience-and-periodontal-health-status-among-children-with-haemophilia-in-new-delhi-india-a-case-control-study
#15
Mridula Goswami, Babita Jangra
PURPOSE: To assess the caries experience and periodontal health status among children with haemophilia in New Delhi. MATERIALS AND METHODS: This case control study was conducted in New Delhi over a 14-month period. Data were collected from 110 children, of which 55 children had haemophilia and 55 were healthy. Caries was assessed in terms of decayed, missing and filled teeth, according to WHO criteria, while periodontal health status was assessed regarding plaque present, and recorded by utilising the Silness and Löe plaque index...
March 20, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28322356/efficacy-of-motivational-interviewing-in-conjunction-with-caries-risk-assessment-micra-programmes-in-improving-the-dental-health-status-of-preschool-children-a-randomised-controlled-trial
#16
Saruta Saengtipbovorn
PURPOSE: To assess the efficacy of motivational interviewing in conjuction with a caries risk assessment (MICRA) programme to improve the dental health status of preschool children. MATERIALS AND METHODS: A randomised controlled trial was conducted among 214 parents or caregivers and their children at Health Centre 54, Bangkok, Thailand, from September 2015 to February 2016. The participants were randomised to the intervention and the control groups (107 participants per group)...
March 20, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28322355/restorative-treatment-decisions-in-posterior-teeth-a-systematic-review
#17
Juliana Jobim Jardim, Sandra Henz, Berenice Barbachan E Silva
PURPOSE: To determine the stage of caries in posterior permanent teeth at which dentists decide to intervene invasively. MATERIALS AND METHODS: A search of the literature from January 1980 to November 2015 available in MEDLINEPubMed, EMBASE, and the Cochrane Library was conducted. The main search terms used were decision-making, restorative treatment, dental caries lesion, occlusal surface, and approximal surface. The inclusion criterion was studies including dentists only...
March 20, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28318391/models-of-caries-formation-around-dental-composite-restorations
#18
J L Ferracane
The main reason cited for the replacement of dental composite restorations is the recurrence of caries. Numerous models-both in vitro, with acid gels or bacterial biofilms, and in situ, with dental appliances-have been used to study caries formation around dental composites. The literature shows that many factors may affect caries formation, including marginal gap formation, gap size, the local chemical environment, the durability of the bonded interface, the extent of bacterial penetration, and the presence of mechanical loading...
April 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28318170/-application-of-saliva-in-disease-diagnosis
#19
Cheng Xingqun, Zhou Xuedong, Xu Xin
Saliva is secreted by salivary glands and performs a variety of functions, including mouth cleaning and protection, antibacterial activity, and digestion. With the rapid progress in salivaomics, saliva became recognized as a potential pool of biological markers. Being a non-invasive and safe source, saliva is a potential substitute for blood in diagnosis and prognosis of diseases. This review summarizes the latest advancement in saliva-related studies and presents the potential value of saliva in early diagnosis of oral diseases, such as dental caries, periodontal disease, cancer, diabetes, and other systemic disorders...
December 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28317563/epidemiology-of-oral-and-maxillofacial-infections
#20
REVIEW
Arvind Babu Rajendra Santosh, Orrett E Ogle, Dwight Williams, Edward F Woodbine
Dental caries and periodontal disease are the most common dental infections and are constantly increasing worldwide. Distribution, occurrence of dental caries, gingivitis, periodontitis, odontogenic infections, antibiotic resistance, oral mucosal infections, and microbe-related oral cancer are important to understand the public impact and methods of controlling such disease. Distribution of human papilloma virus and human immunodeficiency virus -related oral cancers in the US population is presented.
April 2017: Dental Clinics of North America
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