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Dental Caries

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https://www.readbyqxmd.com/read/29774628/efficacy-and-safety-of-brexpiprazole-for-the-treatment-of-acute-schizophrenia-in-japan-a-6-week-randomized-double-blind-placebo-controlled-study
#1
Jun Ishigooka, Shuichi Iwashita, Yoshihiro Tadori
AIMS: This study aimed to evaluate the efficacy, safety, and tolerability of brexpiprazole compared to placebo in Japanese patients with acute schizophrenia. METHODS: We conducted a 6-week, multicenter, double-blind, placebo-controlled, phase 2/3 study in Japan. Patients with acute schizophrenia were randomized (1:1:1:1) to receive brexpiprazole 1, 2, or 4 mg or placebo once a day. The primary endpoint was the change from baseline to week 6 in Positive and Negative Syndrome Scale (PANSS) total scores...
May 18, 2018: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29769814/combined-deficiencies-of-25-hydroxyvitamin-d-and-anemia-in-preschool-children-with-severe-early-childhood-caries-a-case-control-study
#2
Shannon Deane, Robert J Schroth, Atul Sharma, Celia Rodd
Background: Severe early childhood caries (S-ECC) is common and has adverse affects on children's health. Children with S-ECC have been shown to have anemia or vitamin D deficiency. No studies have assessed the presence of combined deficiencies with S-ECC. The purpose of our study was to examine whether those with S-ECC had a higher prevalence of combined anemia and low 25-hydroxyvitamin D (25(OH)D) compared to controls. Covariates associated with elevated parathyroid hormone (PTH), previously noted in S-ECC, were examined...
May 2018: Paediatrics & Child Health
https://www.readbyqxmd.com/read/29769430/oral-lactobacilli-and-salivary-acidic-proline-rich-proteins-aprp-1-2-in-dental-caries
#3
A K Szkaradkiewicz-Karpinska, A Zeidler, O Goslinska-Kuzniarek, K Uram, A Szkaradkiewicz
A previous study shows that levels of acidic salivary proline-rich phosphoproteins-1/2 (APRP-1/2) increase with caries severity. The aim of this study was to examine whether this relationship also depends on the presence of H2 O2 -producing strains of Lactobacillus spp. Adults with severe caries (decayed, missing, and filled teeth (DMFT) > 13.9, n = 28) were compared with similarly aged adults who had minimal caries (DMFT < 5, n = 20). A total of 48 samples of whole unstimulated saliva were collected in the morning and centrifuged...
February 2018: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/29768525/effects-of-a-food-enriched-with-probiotics-on-streptococcus-mutans-and-lactobacillus-spp-salivary-counts-in-preschool-children-a-cluster-randomized-trial
#4
Judy Villavicencio, Lina Maria Villegas, Maria Cristina Arango, Susana Arias, Francia Triana
Probiotics have provided benefits to general health, but they are still insufficient to dental health. This study aimed to evaluate milk supplemented with probiotic bacteria and standard milk, measured by levels of Streptococcus mutans (S. mutans) and Lactobacillus spp., in 3-4-year-old children after 9 months of intervention. The study was a triple-blind, placebo-controlled, randomized trial. The sample was composed of 363 preschoolers attending five child development centers in Cali, Colombia. They were randomized to two groups: children in the intervention group drank 200 mL of milk with Lactobacillus rhamnosus 5x106 and Bifidobacteruim longum 3x106, and children in the control group drank 200 mL of standard milk...
May 14, 2018: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29767840/ethnicity-migration-status-and-dental-caries-experience-among-adults-in-east-london
#5
Elsa K Delgado-Angulo, Wagner Marcenes, Seeromanie Harding, Eduardo Bernabé
OBJECTIVE: To assess the interrelationship between ethnicity, migration status and dental caries experience among adults in East London. METHODS: We analysed data from 1910 adults (16-65 years) representing 9 ethnic groups, who took part in a community-based health survey in East London. Participants completed a supervised questionnaire and were clinically examined by trained dentists. Dental caries was assessed with the number of decayed, missing and filled teeth (DMFT)...
May 16, 2018: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/29766564/personal-oral-hygiene-and-dental-caries-a-systematic-review-of-randomised-controlled-trials
#6
Philippe Pierre Hujoel, Margaux Louise A Hujoel, Georgios A Kotsakis
OBJECTIVE: To conduct a systematic review of randomised trials assessing the association between personal oral hygiene and dental caries in the absence of the confounding effects of fluoride. BACKGROUND: Dental caries continues to affect close to 100% of the global population. There is a century-old conflict on whether dental caries is caused by poor oral hygiene or poorly formed teeth (ie, teeth with dental defects). Resolving this conflict is of significant public health importance as these two hypotheses on dental caries aetiology can lead to different prevention strategies...
May 15, 2018: Gerodontology
https://www.readbyqxmd.com/read/29766414/oral-health-and-oral-health-risk-behaviour-in-children-with-and-without-externalising-behaviour-problems
#7
M Staberg, J G Norén, L Gahnberg, A Ghaderi, C Kadesjö, A Robertson
AIM: This was to study children with early detected externalising behaviour problems compared to matched controls regarding oral health, oral health risk behaviour and the parental evaluation of the child's oral health and dental care. METHODS: Children aged 10-13 years and with externalising behaviour problems, were compared to matched controls. Behavioural characteristics were based on the Strength and Difficulties Questionnaire. The children and their parents completed questionnaires regarding dental fear, tooth brushing, dietary habits and evaluation of oral health and dental care...
May 15, 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29765815/in-vitro-investigation-of-antimicrobial-activities-of-ethnomedicinal-plants-against-dental-caries-pathogens
#8
Mamta Besra, Vipin Kumar
The study aimed to evaluate the antimicrobial activity of medicinal plant extracts against the bacterial pathogens prominent in dental caries. A total of 20 plant species (herbs, shrubs and trees) belonging to 18 genera and 15 families were documented for dental caries. Antimicrobial activity of solvent extracts and essential oil from plants were determined by zone of inhibition on the growth of Streptococcus mutans (MTCC 497) and Lactobacillus acidophilus (MTCC 10307) using the agar well diffusion method. The results of in vitro antimicrobial assay prove that methanol is more successful in the extraction of phytochemicals from plant samples than aqueous solvent, as methanol extracts show higher antimicrobial activity than aqueous extracts against both the test pathogens...
May 2018: 3 Biotech
https://www.readbyqxmd.com/read/29763965/proximal-restoration-increases-the-risk-of-clinical-attachment-loss
#9
Kauê Collares, Flávio F Demarco, Bernardo L Horta, Marcos B Correa
AIM: To estimate the effect of proximal direct restorations in the adjacent periodontal tissues in adults from a birth cohort. MATERIALS AND METHODS: A representative sample (n = 539) of all 5,914 births occurring in Pelotas, Brazil in 1982 was prospectively investigated, being clinical attachment loss (CAL), probing depth (PD) and bleeding on probing (BOP) assessed at 31 yrs-old. For each site, tooth surface was evaluated as sound or restored, being the restoration extension (subgingival or supragingival) and restoration material (composite and amalgam) considered...
May 15, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29763355/risk-factors-of-early-childhood-caries-among-young-children-in-hong-kong-a-cross-sectional-study
#10
Sherry Shiqian Gao, Duangporn Duangthip, Edward Chin Man Lo, Chun Hung Chu
OBJECTIVE: Early childhood caries (ECC) was prevalent in Hong Kong. Children with ECC risk should be identified early for prevention. This study aimed to identify common risk factors of ECC in Hong Kong 3-year-old children. STUDY DESIGN: Sample size calculation showed at least 6,321 of 3-year-old children should be invited in this study. A consent form and a questionnaire enquiring the children's oral health behaviours and social-economic background were distributed to their parents...
May 15, 2018: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29763353/effect-of-probiotic-lactobacillus-reuteri-on-salivary-cariogenic-bacterial-counts-among-groups-of-preschool-children-in-jeddah-saudi-arabia-a-randomized-clinical-trial
#11
Najlaa M Alamoudi, Eman S Almabadi, Eman A El Ashiry, Douaa A El Derwi
OBJECTIVES: To evaluate the effect of probiotic Lactobacilli reuteri lozenges on caries-associated salivary bacterial counts (Mutans streptococci and Lactobacillus), dental plaque accumulation, and salivary buffer capacity in a group of preschool children. STUDY DESIGN: The study group consisted of 178 healthy children (aged 3-6 years). Children were randomly grouped: the experimental group (n = 90) received L. reuteri probiotic lozenges and the control group (n = 88) received placebo lozenges, twice daily, for 28 days...
May 15, 2018: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29763350/fluoride-exposure-in-early-life-as-the-possible-root-cause-of-disease-in-later-life
#12
Tetsuo Nakamoto, H Ralph Rawls
Fluoride, one of the most celebrated ingredients for the prevention of dental caries in the 20th century, has also been controversial for its use in dentifrices and other applications. In the current review, we have concentrated primarily on early-life exposure to fluoride and how it may affect the various organs. The most recent controversial aspects of fluoride are related to toxicity of the developing brain and how it may possibly result in the decrease of intelligence quotient (IQ), autism, and calcification of the pineal gland...
May 15, 2018: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29761342/impact-of-oral-hygiene-and-socio-demographic-factors-on-dental-caries-in-a-suburban-population-in-nigeria
#13
T A Oyedele, A D Fadeju, Y I Adeyemo, C L Nzomiwu, A M Ladeji
AIM: This was to determine dental caries determinants in the study participants. METHODOLOGY: This was a secondary data study extracted from primary data through a school-based study that recruited students from primary and secondary schools in a suburban population in Nigeria. The variables included age, gender, socio-economic status, oral hygiene status, type of parenting, birth rank, family size and presence of dental caries. The diagnosis of dental caries was based on the World Health Oral Health Survey recommendations while oral hygiene was determined using simplified-oral hygiene index (OHI-S)...
May 14, 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29760825/a-current-approach-to-halitosis-and-oral-malodor-a-mini-review
#14
REVIEW
Damla Aksit Bicak
Background: Halitosis, in other words, oral malodor is an important multifactorial health problem affecting the psychological and social life of individuals and is the most common reason for referral to dentists after dental caries and periodontal diseases. Objective: The objective of this review was to present and discuss conventional and recently introduced information about the types, causes, detection and treatment methods of halitosis. Methods: An expanded literature review was conducted which targeted all articles published in peer-reviewed journals relating to the topic of halitosis...
2018: Open Dentistry Journal
https://www.readbyqxmd.com/read/29759350/poor-oral-health-in-patients-with-schizophrenia-a-systematic-review-and-meta-analysis
#15
REVIEW
Mi Yang, Peng Chen, Man-Xi He, Min Lu, Hong-Ming Wang, Jair C Soares, Xiang-Yang Zhang
Increased rates of comorbid physical illness have been commonly reported in patients with schizophrenia. However, there are fewer data on dental disease in these patients. We systematically evaluated existing data on the oral health survey of schizophrenia patients through meta-analysis. Using the available databases, we performed a systematic search to identify the studies examining the oral health in schizophrenia patients from January 1997 to June 2017, based on the inclusion and exclusion criteria. Two investigators extracted the related data independently...
May 11, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29754856/three-dimensional-dental-and-craniofacial-manifestations-in-patients-with-late-diagnosis-of-mucopolysaccharidosis-type-ii-report-of-2-cases
#16
Rafaela de Oliveira Torres, Andréa Vaz Braga Pintor, Fábio Ribeiro Guedes, Lucia Helena Soares Cevidanes, Liana Bastos Freitas-Fernandes, Antônio Carlos de Oliveira Ruellas, Ivete Pomarico Ribeiro de Souza
The objective of this study was to report the clinical evaluation results and 3-dimensional (3-D) dental and craniofacial characteristics observed in 2 male patients with mucopolysaccharidosis type II. The patients were evaluated clinically (soft tissue evaluation, evaluation of occlusion, periodontal and dental examinations) and by using craniofacial computed tomography, with evaluation of 3-D images in ITK-Snap v. 2.2 (Penn Image Computing and Science Laboratory, Philadelphia, PA; http://www.itksnap.org/) and 3-D Slicer (http://www...
April 16, 2018: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29754156/-innovative-application-of-small-molecules-to-influence-pathogenicity-of-dental-plaque
#17
M M Janus, C M C Volgenant, B P Krom
Current preventive measures against infectious oral diseases are mainly focussed on plaque removal and promoting a healthy lifestyle. This in vitro study investigated a third preventive method: maintaining healthy dental plaque with the use of small molecules. As a model of dental plaque, in vitro biofilms were cultivated under conditions that induce pathogenic characteristics. The effect of erythritol and other small molecules on the pathogenic characteristics and bacterial composition of the biofilm was evaluated...
May 2018: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/29754154/-series-caries-prevention-in-historical-perspective-fluoride
#18
H Kalsbeek
Shortly after the Second World War it became known in the Netherlands that fluoride can contribute to the prevention of dental caries. As to how this effect was achieved, opinions differed. Initially, the dominant the view was that fluoride had to be absorbed into the enamel and dentine during tooth formation to make the teeth resistant to caries. Later it was discovered that decalcification of the enamel is inhibited if fluoride is present in the dental plaque. While in the beginning water fluoridation was considered to be the most effective measure to prevent caries, the current position is that tooth brushing with fluoride toothpaste plays the most important role in caries prevention...
May 2018: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/29752831/longitudinal-associations-between-dental-caries-increment-and-risk-factors-in-late-childhood-and-adolescence
#19
Alexandra M Curtis, John VanBuren, Joseph E Cavanaugh, John J Warren, Teresa A Marshall, Steven M Levy
OBJECTIVES: To assess longitudinal associations between permanent tooth caries increment and both modifiable and non-modifiable risk factors, using best subsets model selection. METHODS: The Iowa Fluoride Study has followed a birth cohort with standardized caries exams without radiographs of the permanent dentition conducted at about ages 9, 13, and 17 years. Questionnaires were sent semi-annually to assess fluoride exposures and intakes, select food and beverage intakes, and tooth brushing frequency...
May 12, 2018: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/29752807/oral-health-and-school-performance-in-a-group-of-schoolchildren-from-the-federal-district-brazil
#20
Raquel Francis Almeida, Soraya Coelho Leal, Jordana Guedes Amorim Medonca, Leandro Augusto Hilgert, Ana Paula Dias Ribeiro
OBJECTIVES: To evaluate whether an association exists between school performance, quality of life, dental caries, and dental pain in children between 6 and 8 years of age. METHODS: All 6- to 8-year-old children enrolled in the second year of the six public schools in Paranoá-FD were invited to participate in this cross-sectional study. In total, 374 consented. Dental caries was recorded according to the Caries Assessment Spectrum and Treatment (CAST) index by two trained examiners...
May 12, 2018: Journal of Public Health Dentistry
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