keyword
MENU ▼
Read by QxMD icon Read
search

intranasal steroids

keyword
https://www.readbyqxmd.com/read/27890484/25-years-of-advances-in-definition-classification-and-treatment-of-status-epilepticus
#1
Eugen Trinka, Reetta Kälviäinen
PURPOSE: Status epilepticus (SE) requires not only urgent symptomatic treatment with antiepileptic drugs but also rapid identification and treatment of its cause. This narrative review summarizes the most important advances in classification and treatment of SE. METHOD: Data sources included MEDLINE, EMBASE, ClinicalTrials.gov, and back tracking of references in pertinent studies, reviews, and books. RESULTS: SE is now defined as "a condition resulting either from the failure of the mechanisms responsible for seizure termination or from the initiation of mechanisms, which lead to abnormally, prolonged seizures (after time point t1)...
November 14, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27890006/recent-updates-on-the-systemic-and-local-safety-of-intranasal-steroids
#2
Tae Young Jang, Young Hyo Kim
Allergic rhinitis is a global health problem, and its prevalence rate and socioeconomic burden continue to increase. Intranasal steroid (INS) is the first treatment choice in the majority of patients, because of its ability to effectively control allergic symptoms. However, patients and clinicians are concerned about the potential adverse effects of prolonged INS use. In the present study, the systemic bioavailabilities of several commercially available INSs were researched, and then systemic safeties were reviewed with focus on suppression of the hypothalamus-pituitary-adrenal axis and their effects on pediatric growth...
November 23, 2016: Current Drug Metabolism
https://www.readbyqxmd.com/read/27882840/a-comparison-of-health-care-resource-utilization-and-costs-for-patients-with-allergic-rhinitis-on-single-product-or-free-combination-therapy-of-intranasal-steroids-and-intranasal-antihistamines
#3
Brooke Harrow, Ahmad R Sedaghat, Amanda Caldwell-Tarr, Robert Dufour
BACKGROUND: Allergic rhinitis (AR) is a common condition that can be treated with a number of different therapies. Treatments such as intranasal antihistamines (INAs) and intranasal steroids (INSs) are widely used by AR patients. For some allergy sufferers, a combination of therapies, specifically an INA and an INS, is required to address their symptoms. A new treatment, the formulation of azelastine hydrochloride and fluticasone pro-pionate used as a single spray (MP-AzeFlu), has become available for AR patients who need both types of treatment...
December 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27810015/pediatric-obstructive-sleep-apnea
#4
REVIEW
Zarmina Ehsan, Stacey L Ishman
Screening for obstructive sleep apnea (OSA) with in-laboratory polysomnography is recommended for children with sleep disordered breathing. Adenotonsillectomy is the first-line therapy for pediatric OSA, although intranasal steroids and montelukast can be considered for those with mild OSA and continuous positive airway pressure for those with moderate to severe OSA awaiting surgery, poor surgical candidates or persistent OSA. Bony or soft tissue upper airway surgery is reasonable for children failing medical management or those with persistent OSA following adenotonsillectomy...
December 2016: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/27809411/long-term-low-dose-macrolides-for-chronic-rhinosinusitis-in-adults-a-systematic-review-of-the-literature
#5
Andrea Lasso, Pourya Masoudian, Jason G Quinn, Juthaporn Cowan, Varant Labajian, James P Bonaparte, Shaun Kilty
BACKGROUND: Chronic Rhinosinusitis is a very common inflammatory disease that impairs quality of life and is associated with high healthcare spending. Chronic rhinosinusitis treatment commonly involves the use of intranasal corticosteroids, oral antibiotics and surgery. Macrolides have been identified as a potential treatment option for chronic rhinosinusitis due to their immunomodulatory effects; however the evidence supporting their use is still conflicting. OBJECTIVE: The purpose of this systematic review was to evaluate new evidence along with previously reported studies of the use of macrolides in the treatment of chronic rhinosinusitis...
November 3, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27801958/nasal-obstructive-disorders-induce-medical-treatment-failure-in-pediatric-persistent-allergic-rhinitis-the-nodpar-study
#6
Franklin S Mariño-Sánchez, Meritxell Valls-Mateus, Karen Ruiz-Echevarría, Isam Alobid, Paulina Cardenas-Escalante, Rosa Jiménez-Feijoo, Jaime Lozano-Blasco, María T Giner-Muñoz, Jesús Rodríguez-Jorge, Oliver Haag, Ana M Plaza-Martin, Joaquim Mullol
BACKGROUND: Allergic rhinitis (AR) is the most common chronic disease among children. To characterize the disease, a modified classification of severity (m-ARIA) has recently been validated in AR children. When medical treatment fails, surgery for nasal obstructive disorders (NOD) may be a therapeutic option. Our objective was to assess the prevalence of NOD and their influence in medical treatment response among children with persistent AR (PER). METHODS: In a prospective, real-life study, 130 pediatric PER patients (13...
November 1, 2016: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/27747804/intranasal-fluticasone-propionate-observational-cohort-safety-studies-reviewing-evidence-from-databases-on-two-continents
#7
Kourtney J Davis, David Hinds, Stephen P Motsko, Earl Goehring, Judith K Jones
PURPOSE: Our objective was to highlight the importance of database selection in observational research and to determine the incidence of corticosteroid-related events in patients exposed to fluticasone propionate intranasal spray (FPNS) compared with other intranasal steroids (INS). METHODS: After a feasibility study using an electronic medical record database in the UK (1990-2002), a retrospective cohort study was conducted using a large administrative claims database in the USA from 1994 to 2002 comparing the incidence and rate ratios of steroid-related events among intermittent, sub-chronic, and chronic FPNS use and other INS use episodes...
March 2016: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/27714988/intranasal-delivery-of-natesto%C3%A2-testosterone-gel-and-its-effects-on-doping-markers
#8
Geoffrey D Miller, Vinod Nair, M Scott Morrison, Maggie Summers, Stuart E Willick, Daniel Eichner
The laboratory profile of intranasal testosterone gel has not been previously reported from an anti-doping perspective. Because intranasal testosterone gel is newly available as a commercial product, we sought to examine the laboratory parameters following administration of this formulation, with particular attention to anti-doping guidelines. Five healthy and active male subjects were administered testosterone intranasal gel three times daily for four weeks, using a pattern of five consecutive days on, two days off...
November 2016: Drug Testing and Analysis
https://www.readbyqxmd.com/read/27650241/allergy-medications-during-pregnancy
#9
REVIEW
Alexei Gonzalez-Estrada, Stephen A Geraci
Allergic diseases are common in women of childbearing age. Both asthma and atopic conditions may worsen, improve or remain the same during pregnancy. Primary care physicians commonly encounter women receiving multiple medications for pre-existing atopic conditions, who then become pregnant and require medication changes to avoid potential fetal injury or congenital malformations. Each medication should be evaluated; intranasal and inhaled steroids are relatively safe to continue during pregnancy (budesonide is the drug of choice), second-generation antihistamines of choice are cetirizine and loratadine, leukotriene receptor antagonists are safe, sparing use of oral decongestants during the first trimester and omalizumab may be used for both uncontrolled asthma and for antihistamine-resistant urticaria...
September 2016: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/27613466/efficacy-of-the-novel-nasal-steroid-s0597-tested-in-an-environmental-exposure-unit
#10
Anne K Ellis, Lisa M Steacy, Abhijeet Joshi, Shravanti Bhowmik, Atul Raut
BACKGROUND: S0597 is a novel glucocorticosteroid that was formulated as an intranasal spray to treat seasonal allergic rhinitis (SAR). In a previous phase 2 study, doses of 100 to 400 μg twice daily were well tolerated and more effective than placebo for improving nasal symptoms induced by grass pollen. OBJECTIVE: To assess the clinical efficacy and safety of a once-daily S0597 nasal spray for treatment of SAR induced by ragweed pollen in an environmental exposure unit (EEU)...
September 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27610609/amoxicillin-clavulanate-for-patients-with-acute-exacerbation-of-chronic-rhinosinusitis-a-prospective-double-blinded-placebo-controlled-trial
#11
Henrique Augusto Cantareira Sabino, Fabiana Cardoso Pereira Valera, Davi Casale Aragon, Marina Zilio Fantucci, Carolina Carneiro Titoneli, Roberto Martinez, Wilma T Anselmo-Lima, Edwin Tamashiro
BACKGROUND: The management of acute exacerbation of chronic rhinosinusitis (AECRS) is still under debate, especially because there are no adequate studies to support a best-evidence treatment for this condition. Antibiotic use for AECRS has been recommended based on extrapolation of data from acute rhinosinusitis (ARS) or non-placebo-controlled studies. This study aimed to evaluate whether antibiotic therapy modifies the course of AECRS in a randomized, placebo-controlled study. METHODS: Patients with AECRS were randomized in a double-blinded manner (2:1 ratio) to receive either amoxicillin-clavulanate 875 mg/125 mg twice daily (BID) (AMX-CLAV, n = 21) or placebo capsules (n = 11) during 14 days...
September 9, 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27560503/utilization-patterns-of-topical-intranasal-steroid-therapy-for-chronic-rhinosinusitis-a-canadian-population-based-analysis
#12
Luke Rudmik, Yuan Xu, Mingfu Liu, Ceris Bird, Edward Kukec, Hude Quan
Importance: Practice guidelines have provided a strong recommendation for the daily use of topical intranasal steroid therapy for patients with chronic rhinosinusitis (CRS). Deficiencies in utilization of intranasal steroid therapy may represent a gap in quality of care. Objective: To evaluate the utilization patterns of topical intranasal steroid therapy for CRS in the Canadian population. Design, Setting, and Participants: Retrospective review of a Canadian population-based health care administrative database...
November 1, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27500891/current-trends-in-topical-therapies-for-chronic-rhinosinusitis-update-and-literature-review
#13
Rickul Varshney, Jivianne T Lee
INTRODUCTION: Chronic rhinosinusitis (CRS) affects millions of patients worldwide. The disease is multifactorial with influences including anatomic factors, immunological disturbances, and altered sinonasal microbiome. Although oral medications are effective in controlling some symptoms, they are associated with side effects and long-term use is not ideal. Thus, topical therapies have emerged as an alternative delivery method for localized, high-concentration medication with less side effects...
August 8, 2016: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/27466026/role-of-antioxidants-on-the-clinical-outcome-of-patients-with-perennial-allergic-rhinitis
#14
B Chauhan, M Gupta, K Chauhan
BACKGROUND: Antioxidants have a preventive or therapeutic role in oxygen free radical-mediated cell and tissue damage. The study aimed to investigate the therapeutic effects of antioxidants and intranasal steroid fluticasone furoate (FF) on the clinical outcome of patients with perennial allergic rhinitis. METHODS: Subjects with perennial allergic rhinitis (n = 61) were randomly divided into two groups, group A (n = 30) received FF and group B (n = 31) received FF with antioxidants for 6 weeks...
July 26, 2016: Allergy & Rhinology
https://www.readbyqxmd.com/read/27392904/calcitonin-effects-on-shoulder-adhesive-capsulitis
#15
Alireza Rouhani, Mohsen Mardani-Kivi, Mohammadreza Bazavar, Mahmood Barzgar, Ali Tabrizi, Keyvan Hashemi-Motlagh, Khashayar Saheb-Ekhtiari
INTRODUCTION: Adhesive capsulitis (frozen shoulder) is a relatively prevalent disease of shoulder and affects soft tissue of glenohumeral joint. Signs include painful restricted motion and disability of the patient in daily activities. Calcitonin is a thyroid hormone, and its effectiveness has been demonstrated in painful conditions. The presents study aims to evaluate the effect of calcitonin in treating shoulder adhesive capsulitis. METHOD: This double-blinded randomized clinical trial was conducted on 64 patients suffering from shoulder adhesive capsulitis...
August 2016: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/27375045/sex-differences-in-the-effects-of-social-defeat-on-brain-and-behavior-in-the-california-mouse-insights-from-a-monogamous-rodent
#16
Michael Q Steinman, Brian C Trainor
Women are nearly twice as likely as men to be diagnosed with major depressive disorder, yet the use of female animal models in studying the biological basis of depression lags behind that of males. The social defeat model uses social stress to generate depression-like symptoms in order to study the neurobiological mechanisms. In general, social defeat is difficult to apply in female rodents. However, male and female California mice (Peromyscus californicus) are territorial. This allows defeat to be studied in both sexes...
June 30, 2016: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/27373328/the-safety-of-intranasal-steroids-during-pregnancy-a%C3%A2-good-start
#17
EDITORIAL
Jennifer A Namazy, Michael Schatz
No abstract text is available yet for this article.
July 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27365873/hydrocodone-snorting-leading-to-hypersensitivity-pneumonitis
#18
Lakshmi Kant Pathak, Vimala Vijayaraghavan
We present a case of hypersensitivity pneumonitis caused by intranasal abuse of the prescription narcotic hydrocodone. The patient's clinical course was complicated by acute respiratory failure. A chest radiograph showed diffuse bilateral opacities. The patient was treated with noninvasive ventilation, a high dose of intravenous steroids, and bronchodilators, resulting in improvement of symptoms and radiographic appearance.
July 2016: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/27354761/the-effect-of-long-term-use-of-intranasal-steroids-on-intraocular-pressure
#19
Ali Şimşek, Cem Bayraktar, Sedat Doğan, Mehmet Karataş, Yasin Sarıkaya
Long-term use of topical nasal steroids (especially older generation steroids) has been shown to elevate intraocular pressure (IOP), but newer intranasal steroids are thought to have a minimal effect on IOP because of their low bioavailability. This study aimed to investigate alterations in IOP with two commonly used intranasal steroids for a 6-month period of time. One-hundred allergic rhinitis patients, divided equally into two groups, used mometasone furoate and fluticasone furoate intranasal steroids for 6 months...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27328556/clinical-question-nasal-saline-or-intranasal-corticosteroids-to-treat-allergic-rhinitis-in-children
#20
REVIEW
Stefani Madison, Elizabeth Aubrey Brown, Rachel Franklin, Elizabeth A Wickersham, Laine H McCarthy
CLINICAL QUESTION: In pediatric populations, is nasal saline irrigation as effective as intranasal corticosteroids at relieving allergic rhinitis symptoms? ANSWER: No. Intranasal steroids are more effective than nasal saline alone to reduce symptoms of allergic rhinitis (AR) in children. Combination therapy further improves symptom reduction. LEVEL OF EVIDENCE FOR THE ANSWER: B SEARCH TERMS: Allergic Rhinitis, Nasal Saline, Nasal corticosteroids, children younger than age 18...
April 2016: Journal of the Oklahoma State Medical Association
keyword
keyword
53080
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"