Qin Cai, Hong-Jing Zha, Shi-Ying Yuan, Xing Sun, Xin Lin, Xin-Yu Zheng, Ying-Xian Qian, Ru-Feng Xia, Yue-Shan Luo, Zhimian Shi, Jun-Cheng Su, Luo-Sheng Wan
Euphorbia diterpenoids possess inhibitory effects of Kv1.3 ion channel, but most of this research has focused on diterpenoids with jatrophane-related or ingenane-related skeletons. In the present study, nine undescribed ( 1 - 9 ) and 16 known ( 10 - 25 ) diterpenoids, based on jatrophane, lathyrane, ingenane, abietane, and atisane skeletons, were identified from the methanol extract of the aerial parts of Euphorbia fischeriana . The structures were established by analysis of the spectroscopic data as well as by single-crystal X-ray diffraction analysis...
October 5, 2023: Journal of Natural Products