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https://www.readbyqxmd.com/read/28213703/proximal-tibial-bony-and-meniscal-slopes-are-higher-in-acl-injured-subjects-than-controls-a-comparative-mri-study
#1
Ashraf Elmansori, Timothy Lording, Raphaël Dumas, Khalifa Elmajri, Philippe Neyret, Sébastien Lustig
PURPOSE: Increased tibial slope is reported as a risk factor of non-contact anterior cruciate ligament (ACL) injury, but the effect of the soft tissues on slope remains unclear. The primary aims of this study were to compare the tibial bony and soft tissue slopes between patients with and without ACL injury, and to investigate the relationship between the meniscal slopes (MS) and the tibial bony slope. Our hypothesis was that the menisci would correct the inclination of the bony tibial slope towards the horizontal...
February 17, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28210945/mr-imaging-evaluation-of-the-postoperative-meniscus
#2
REVIEW
A Russo, R Capasso, C Varelli, A Laporta, M Carbone, G D'Agosto, S Giovine, M Zappia, A Reginelli
MR imaging has been widely evaluated in the assessment of patients with recurrent or residual symptoms following meniscal surgery. Importantly, the causes of such symptoms may relate to failure or complication of the surgical procedure, a possible recurrent or residual meniscal tear, or may be related to other causes of joint symptoms, including tears of the contralateral meniscus, or local hyaline cartilage, or marrow abnormalities subjacent to or distant to the meniscal surgical site. The complex diagnostic issues involved in the MR imaging evaluation of the postoperative meniscus were identified in early MR imaging studies...
February 16, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28210647/association-of-quadriceps-strength-and-psychosocial-factors-with-single-leg-hop-performance-in-patients-with-meniscectomy
#3
Chao-Jung Hsu, Steven Z George, Terese L Chmielewski
BACKGROUND: Clinicians use the single-leg hop test to assess readiness for return to sports after knee injury. Few studies have reported the results of single-leg hop testing after meniscectomy. Additionally, the contributions of impairments in quadriceps strength and psychosocial factors to single-leg hop performance are unknown. PURPOSE: To compare single-leg hop performance (distance and landing mechanics) between limbs and to examine the association of single-leg hop performance with quadriceps strength and psychosocial factors in patients with meniscectomy...
December 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28203597/intra-articular-implantation-of-mesenchymal-stem-cells-part-1-a-review-of-the-literature-for-prevention-of-postmeniscectomy-osteoarthritis
#4
Matthew J Kraeutler, Justin J Mitchell, Jorge Chahla, Eric C McCarty, Cecilia Pascual-Garrido
Osteoarthritis (OA) after a partial or total meniscectomy procedure is a common pathology. Because of the high incidence of meniscectomy in the general population, as well as the significant burden of knee OA, there is increasing interest in determining methods for delaying postmeniscectomy OA. Biological therapies, including mesenchymal stem cells (MSCs), induced pluripotent stem cells (iPSCs), and platelet-rich plasma (PRP), have been proposed as possible therapies that could delay OA in this and other settings...
January 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28203596/intra-articular-implantation-of-mesenchymal-stem-cells-part-2-a-review-of-the-literature-for-meniscal-regeneration
#5
Matthew J Kraeutler, Justin J Mitchell, Jorge Chahla, Eric C McCarty, Cecilia Pascual-Garrido
Knee osteoarthritis (OA) after partial or total meniscectomy is a prevalent issue that patients must face. Various methods of replacing meniscal tissue have been studied to avoid this progression, including meniscal allograft transplantation, meniscal scaffolds, and synthetic meniscus replacement. Studies have shown that meniscal scaffolds may improve symptoms but have not been shown to prevent progression of OA. Recently, mesenchymal stem cells (MSCs) have been proposed as a possible biological therapy for meniscal regeneration...
January 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28203587/why-do-authors-differ-with-regard-to-the-femoral-and-meniscal-anatomic-parameters-of-the-knee-anterolateral-ligament-dissection-by-layers-and-a-description-of-its-superficial-and-deep-layers
#6
Camilo Partezani Helito, Carlos do Amaral, Yuri da Cunha Nakamichi, Riccardo Gomes Gobbi, Marcelo Batista Bonadio, Renato José Mendonça Natalino, José Ricardo Pécora, Tulio Pereira Cardoso, Gilberto Luis Camanho, Marco Kawamura Demange
BACKGROUND: No consensus exists regarding the anatomic characteristics of the knee anterolateral ligament (ALL). A critical analysis of the dissections described in previous studies allows the division of the ALL into 2 groups with similar characteristics. The presence of considerable variability suggests that the authors may not be referring to the same structure. PURPOSE/HYPOTHESIS: To perform a lateral anatomic dissection, by layers, seeking to characterize the 2 variants described for the ALL on the same knee...
December 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28203586/comparison-of-kinematics-and-tibiofemoral-contact-pressures-for-native-and-transplanted-lateral-menisci
#7
Patrick C McCulloch, Donald Dolce, Hugh L Jones, Andrea Gale, Michael G Hogen, Jason Alder, Jeremiah E Palmer, Philip C Noble
BACKGROUND: Lateral meniscus transplantation is a proven treatment option for the meniscus-deficient knee, yet little is known about meniscal kinematics, strain, and tibiofemoral contact pressure changes after transplantation or the effect of altered root position in lateral meniscus transplantation. PURPOSE: To compare the native lateral meniscal kinematics, strain, and tibiofemoral contact pressures to a best-case scenario meniscus transplant with perfectly matched size and position and to determine how sensitive these factors are to subtle changes in shape and position by using a nonanatomic meniscus transplant position...
December 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28197693/predictive-factors-for-osteochondritis-dissecans-of-the-lateral-femoral-condyle-concurrent-with-a-discoid-lateral-meniscus
#8
Junsei Takigami, Yusuke Hashimoto, Tomohiro Tomihara, Shinya Yamasaki, Koji Tamai, Kyoko Kondo, Hiroaki Nakamura
PURPOSE: Osteochondritis dissecans (OCD) of the lateral femoral condyle is relatively rare, and it is often reported in combination with discoid lateral meniscus. However, little is known about the mechanism underlying this connection. Predictive factors for OCD coinciding with discoid lateral meniscus in Japanese children and adolescents were assessed. METHODS: During 2000-2015, 152 knees in 133 patients aged 5-15 years were diagnosed with symptomatic complete discoid lateral meniscus...
February 14, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28186682/repair-of-torn-avascular-meniscal-cartilage-using-undifferentiated-autologous-mesenchymal-stem-cells-from-in-vitro-optimization-to-a-first-in-human-study
#9
Michael R Whitehouse, Nicholas R Howells, Michael C Parry, Eric Austin, Wael Kafienah, Kyla Brady, Allen E Goodship, Jonathan D Eldridge, Ashley W Blom, Anthony P Hollander
Meniscal cartilage tears are common and predispose to osteoarthritis (OA). Most occur in the avascular portion of the meniscus where current repair techniques usually fail. We described previously the use of undifferentiated autologous mesenchymal stem cells (MSCs) seeded onto a collagen scaffold (MSC/collagen-scaffold) to integrate meniscal tissues in vitro. Our objective was to translate this method into a cell therapy for patients with torn meniscus, with the long-term goal of delaying or preventing the onset of OA...
December 15, 2016: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28184957/partial-meniscectomy-provides-no-benefit-for-symptomatic-degenerative-medial-meniscus-posterior-root-tears
#10
Aaron J Krych, Nick R Johnson, Rohith Mohan, Diane L Dahm, Bruce A Levy, Michael J Stuart
PURPOSE: Medial meniscus posterior root tears (MMPRTs) are recognized as a source of pain and dysfunction, but treatment options remain a challenge. The purpose of the study was to determine (1) the efficacy of partial meniscectomy to treat MMPRTs compared to a matched group of non-operatively treated MMPRTs, and (2) risk factors for worse clinical and radiographic outcome. METHODS: This retrospective comparative study was performed to include patients with complete, isolated MMPRTs with documented clinical symptoms and were treated with arthroscopic partial meniscectomy (PMM) and a minimum 2-year follow-up...
February 9, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28169595/tissue-derived-extracellular-matrix-bioscaffolds-emerging-applications-in-cartilage-and-meniscus-repair
#11
Farrah A Monibi, James Lee Cook
Musculoskeletal injuries are a common and significant problem in orthopaedic practice. Given the long-term consequences of unaddressed cartilage and meniscal pathology, a number of treatments have been attempted to stimulate repair or to replace the injured tissue. Despite advances in orthopaedic surgery, effective treatments for cartilage and meniscus injuries remain a common and significant clinical challenge. Tissue engineering is a developing field that aims to regenerate injured tissues with a combination of cells, scaffolds, and signals...
February 7, 2017: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/28169099/the-role-of-medial-meniscus-posterior-root-tear-and-proximal-tibial-morphology-in-the-development-of-spontaneous-osteonecrosis-and-osteoarthritis-of-the-knee
#12
Ryota Yamagami, Shuji Taketomi, Hiroshi Inui, Keitaro Tahara, Sakae Tanaka
BACKGROUND: Medial meniscus posterior root tear (MMPRT) has been reported to play a key role in the development of spontaneous osteonecrosis of the knee (SONK) and osteoarthritis (OA) of the knee. However, little is known about the differences in the development of SONK and OA after MMPRT. The purpose of this study was to investigate the factors contributing to the development of these conditions. METHODS: We evaluated the existence of MMPRT and the extent of medial meniscal extrusion in preoperative magnetic resonance images and proximal tibial morphology in radiographs of 45 patients with SONK and 104 patients with OA who underwent knee surgery...
February 3, 2017: Knee
https://www.readbyqxmd.com/read/28165810/the-origin-and-distribution-of-cd68-cd163-and-%C3%AE-sma-positive-cells-in-the-early-phase-after-meniscal-resection-in-a-parabiotic-rat-model
#13
Shozaburo Terai, Yusuke Hashimoto, Kumi Orita, Shinya Yamasaki, Junsei Takigami, Takafumi Shinkuma, Takanori Teraoka, Yohei Nishida, Masafumi Takahashi, Hiroaki Nakamura
We previously reported that circulating peripheral blood-borne cells (PBCs) contribute to early-phase meniscal reparative change. Because macrophages and myofibroblasts are important contributors of tissue regeneration, we examined their origin and distribution in the reparative meniscus. Reparative menisci were evaluated at 1, 2, and 4 weeks post-meniscectomy by immunohistochemistry to locate monocytes and macrophages (stained positive for CD68 and CD163), and myofibroblasts (stained positive for αSMA). Of the total number of cells, 13% were CD68(+) at 1 week post-meniscectomy, which decreased to 1% by 4 weeks post-meniscectomy; of these, almost half of CD68(+) cells (49...
February 6, 2017: Connective Tissue Research
https://www.readbyqxmd.com/read/28163243/long-term-assessment-of-meniscal-extrusion-after-meniscal-repair
#14
David Dujardin, Renaud Siboni, Lukshe Kanagaratnam, Phillipe Boisrenoult, Phillipe Beaufils, Nicolas Pujol
BACKGROUND: Arthroscopic meniscal repair limits the medium-term risk of radiological osteoarthritis. Magnetic resonance imaging (MRI) cannot provide an accurate assessment of meniscal healing but may show harbingers of osteoarthritis such as meniscal extrusion.The objective of this study was to assess long-term meniscal extrusion after meniscal repair. HYPOTHESIS: Arthroscopic meniscal suture is not followed by meniscal extrusion and can, therefore, provide good knee function in the long term...
February 2, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28162881/midterm-results-of-osteochondral-allograft-transplantation-to-the-humeral-head
#15
Andrew J Riff, Adam B Yanke, Jason J Shin, Anthony A Romeo, Brian J Cole
BACKGROUND: This study evaluated clinical outcomes of osteochondral allograft (OCA) transplantation for humeral head osteochondral defects. We hypothesized that patients with isolated humeral head disease would achieve favorable results and that patients with bipolar disease would experience inferior outcomes. METHODS: We identified patients who underwent humeral head OCA transplantation. Subjective questionnaire data were obtained preoperatively and at a minimum of 2 years postoperatively...
February 2, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28161573/chondrogenically-primed-tonsil-derived-mesenchymal-stem-cells-encapsulated-in-riboflavin-induced-photocrosslinking-collagen-hyaluronic-acid-hydrogel-for-meniscus-tissue-repairs
#16
Rachel H Koh, Yinji Jin, Byung-Jae Kang, Nathaniel S Hwang
: Current meniscus tissue repairing strategies involve partial or total meniscectomy, followed by allograft transplantation or synthetic material implantation. However, allografts and synthetic implants have major drawbacks such as the limited supply of grafts and lack of integration into host tissue, respectively. In this study, we investigated the effects of conditioned medium (CM) from meniscal fibrochondrocytes and TGF-β3 on tonsil-derived mesenchymal stem cells (T-MSCs) for meniscus tissue engineering...
February 1, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28160306/a-modified-tibial-compression-test-for-the-detection-of-meniscal-injury-in-dogs
#17
S Valen, C McCabe, E Maddock, S Bright, B Keeley
OBJECTIVE: To assess diagnostic efficacy of a modified tibial compression test in predicting medial meniscal injury in dogs with cranial cruciate ligament failure. METHODS: Dogs admitted for surgical stabilisation of stifles with cranial cruciate ligament failure were examined by five preoperative physical tests to assess medial meniscal injury. Results of each physical test were compared with findings at arthrotomy and used to calculate sensitivities, specificities, positive and negative predictive values...
February 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/28159718/mechanical-function-near-defects-in-an-aligned-nanofiber-composite-is-preserved-by-inclusion-of-disorganized-layers-insight-into-meniscus-structure-and-function
#18
Sonia Bansal, Sai Mandalapu, Céline Aeppli, Feini Qu, Spencer E Szczesny, Robert L Mauck, Miltiadis H Zgonis
: The meniscus is comprised of circumferentially aligned fibers that resist the tensile forces within the meniscus (i.e., hoop stress) that develop during loading of the knee. Although these circumferential fibers are severed by radial meniscal tears, tibial contact stresses do not increase until the tear reaches ∼90% of the meniscus width, suggesting that the severed circumferential fibers still bear load and maintain the mechanical functionality of the meniscus. Recent data demonstrates that the interfibrillar matrix can transfer strain energy to disconnected fibrils in tendon fascicles...
January 31, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28153861/patient-reported-outcomes-in-patients-undergoing-arthroscopic-partial-meniscectomy-for-traumatic-or-degenerative-meniscal-tears-comparative-prospective-cohort-study
#19
Jonas Bloch Thorlund, Martin Englund, Robin Christensen, Nis Nissen, Kenneth Pihl, Uffe Jørgensen, Jeppe Schjerning, L Stefan Lohmander
OBJECTIVES:  To compare patient reported outcomes from before surgery to 52 weeks after surgery between individuals undergoing arthroscopic partial meniscectomy for traumatic meniscal tears and those for degenerative meniscal tears. DESIGN:  Comparative prospective cohort study. SETTING:  Four public orthopaedic departments in the Region of Southern Denmark. Participants were recruited between 1 February 2013 and 31 January 2014, and at one of the original four hospitals from 1 February 2014 to 31 January 2015...
February 2, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28152576/evaluation-of-novel-biodegradable-three-armed-and-hyper-branched-tissue-adhesives-in-a-meniscus-explant-model
#20
A I Bochyńska, G Hannink, R Verhoeven, D W Grijpma, P Buma
Current treatment methods to repair meniscal tears do not bring fully satisfactory results. Tissue adhesives are considered promising alternatives, since they are easy to apply and cause minimal tissue trauma. The first aim of this study was to analyze the adhesive properties of and tissue response to two recently developed biodegradable block copolymeric three-armed- and hyper-branched tissue adhesives. The second aim was to investigate if tissue surface modification with collagenase improves the attachment of the adhesives and increases the healing potential of the tissue...
February 2, 2017: Journal of Biomedical Materials Research. Part A
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