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https://www.readbyqxmd.com/read/28816515/how-should-we-secure-our-transplanted-meniscus-a-meta-analysis
#1
Julio J Jauregui, Zhan Dong Wu, Sean Meredith, Cullen Griffith, Jonathan D Packer, R Frank Henn
BACKGROUND: Meniscal allograft transplant (MAT) is a salvage procedure for young patients with symptomatic meniscal deficiency. Although many studies report good outcomes, MAT remains controversial, and an optimal fixation technique for the meniscus roots is debated. PURPOSE: To assess the overall outcome of MAT and compare the results of different meniscal root fixation techniques. STUDY DESIGN: Meta-analysis. METHODS: Following specific guidelines, we systematically evaluated all current literature for studies reporting on the outcomes of patients who underwent MAT...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28815275/similar-failure-rate-in-immediate-post-operative-weight-bearing-versus-protected-weight-bearing-following-meniscal-repair-on-peripheral-vertical-meniscal-tears
#2
Bryan Perkins, Kyle R Gronbeck, Ruixian Alexander Yue, Marc A Tompkins
PURPOSE AND HYPOTHESIS: Post-operative weight bearing after meniscal repair is a point of debate among physicians. This study sought to evaluate whether patients adhering to an immediate WBAT rehabilitation programme have a higher failure rate compared to those adhering to a more traditional, protected, NWB status following meniscal repair. The null hypothesis was that there would be no difference in failure between the two groups. METHODS: A retrospective review of meniscal repair patients greater than 5 years from surgery was performed for patients receiving meniscal repair treatment...
August 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28812037/a-retrospective-analysis-of-concurrent-pathology-in-acl-reconstructed-knees-of-elite-alpine-ski-racers
#3
Matthew J Jordan, Patricia Doyle-Baker, Mark Heard, Per Aagaard, Walter Herzog
BACKGROUND: Anterior cruciate ligament (ACL) tear is the most frequent injury in alpine ski racing, and there is a high prevalence of ACL reinjury. Limited data exist on the concurrent pathology with primary ACL tears in elite alpine ski racers and the magnitude of injury progression after primary ACL reconstruction (ACLR). PURPOSE: To evaluate (1) the involvement of intra-articular and multiligament pathologies at the time of primary ACLR, (2) the subsequent progression in meniscal/chondral injuries, and (3) the occurrence of ACL reinjury in elite alpine ski racers...
July 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28809636/-arthroscopic-finding-of-knee-joint-in-relation-to-age-and-its-comparison-with-pre-operative-clinical-finding-a-retrospective-study
#4
P Látal, K Šimeček, M Kloub
PURPOSE OF THE STUDY In the retrospective study of two South Bohemian centres we present the comparison of pre-operative anamnestic clinical signs in relation to the arthroscopic intraoperative finding. The obtained data is used also to evaluate the arthroscopic finding in relation to age and sex. MATERIAL AND METHODS The arthroscopic findings of patients who underwent surgery in 2013-2014 period (1.1.2013-31.12.2014) at the Department of Trauma Surgery of České Budějovice Hospital, a.s. and in 2014 (1.1...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28808951/what-is-the-diagnostic-accuracy-of-the-duck-walk-test-in-detecting-meniscal-tears
#5
A Van der Post, J C A Noorduyn, V A B Scholtes, E L A R Mutsaerts
BACKGROUND: Clinical weightbearing provocation tests, like the duck walk test, may be of value in diagnosing or screening for medial meniscal tears. However, evidence of the diagnostic accuracy of the duck walk test is lacking. QUESTIONS/PURPOSES: (1) To determine the sensitivity and specificity of the duck walk test in diagnosing medial meniscal tears. (2) To determine whether tear location, tear cause (traumatic versus degenerative), and ACL insufficiency were associated with differences in the sensitivity and specificity of the test...
August 14, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28806092/comparable-outcomes-after-bucket-handle-meniscal-repair-and-vertical-meniscal-repair-can-be-achieved-at-a-minimum-2-years-follow-up
#6
Gilbert Moatshe, Mark E Cinque, Jonathan A Godin, Alexander R Vap, Jorge Chahla, Robert F LaPrade
BACKGROUND: Meniscal tears can lead to significant pain and disability, necessitating surgical treatment. Nondisplaced vertical tears are usually smaller in size and can be repaired in most cases; however, bucket-handle tears are usually larger and displaced, and the repair of these tears can be challenging. Purpose/Hypothesis: The purpose was to report the outcomes after inside-out vertical mattress suture meniscal repair of bucket-handle tears and to compare these outcomes with those of patients who underwent repair of nondisplaced vertical meniscal tears with a minimum of 2 years' follow-up...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28805136/the-ovine-model-for-meniscus-tissue-engineering-considerations-of-anatomy-function-implantation-and-evaluation
#7
Andrzej Brzezinski, Salim A Ghodbane, Jay M Patel, Barbara A Perry, Charles J Gatt, Michael G Dunn
Meniscus injuries represent one of the most-common intra-articular knee injuries. The current treatment options include meniscectomy and allograft transplantation, both with poor long-term outcomes. Therefore, there is a need for regenerative techniques to restore meniscal function. In order to pre-clinically test scaffolds for meniscus replacement, large-animal models need to be established and standardized. This review establishes the anatomical and compositional similarities between the human and sheep menisci and provides guidance for implantation and evaluation of such devices...
August 12, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28790437/meniscal-ossicles-as-micro-ct-imaging-biomarker-in-a-rodent-model-of-antigen-induced-arthritis-a-synchrotron-based-x-ray-pilot-study
#8
Sandro Donato, Serena Pacilè, Federico Colombo, Chiara Garrovo, Simeone Dal Monego, Paolo Macor, Giuliana Tromba, Stefania Biffi
It is increasingly recognized that early detection of bone erosion plays an important role in the overall evaluation of rheumatoid arthritis and in the choice of the correct treatment approach. Since an appropriate use of imaging biomarkers in preclinical settings offers the prospect of smaller and optimized sample size, in the present study we define an anatomical imaging biomarker that could be objectively measured from micro-CT imaging data as an indicator of bone erosion in arthritis process. The well-characterized antigen-induced arthritis (AIA) model in rats was used...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28783120/platelet-rich-fibrin-facilitates-rabbit-meniscal-repair-by-promoting-meniscocytes-proliferation-migration-and-extracellular-matrix-synthesis
#9
Chin-Chean Wong, Tzong-Fu Kuo, Tsung-Lin Yang, Yang-Hwei Tsuang, Ming-Fang Lin, Chung-Hsun Chang, Yun-Ho Lin, Wing P Chan
Although platelet-rich fibrin (PRF) has been used in clinical practice for some time, to date, few studies reveal its role as a bioactive scaffold in facilitating meniscal repair. Here, the positive anabolic effects of PRF on meniscocytes harvested from the primary culture of a rabbit meniscus were revealed. The rabbit meniscocytes were cultured with different concentrations of PRF-conditioned medium, and were evaluated for their ability to stimulate cell migration, proliferation, and extracellular matrix formation...
August 7, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28780004/prognostic-factors-for-all-inside-meniscal-repair-an-87-case-series
#10
LoïcLaurendon, Thomas Neri, Frédéric Farizon, Rémi Philippot
INTRODUCTION: Repair is indicated for tears in non-degenerative menisci. The literature reports a 15% failure rate for all-inside repair. The aim of the present study was to determine prognostic factors for failure of all-inside meniscal repair. The study hypothesis was that epidemiological, clinical and surgical factors affect success. MATERIALANDMETHODS: A retrospective study included 87 meniscal repair procedures, with or without anterior cruciate ligament (ACL) tear...
August 2, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28772388/an-overview-of-scaffold-design-and-fabrication-technology-for-engineered-knee-meniscus
#11
REVIEW
Jie Sun, Sanjairaj Vijayavenkataraman, Hang Liu
Current surgical treatments for meniscal tears suffer from subsequent degeneration of knee joints, limited donor organs and inconsistent post-treatment results. Three clinical scaffolds (Menaflex CMI, Actifit(®) scaffold and NUsurface(®) Meniscus Implant) are available on the market, but additional data are needed to properly evaluate their safety and effectiveness. Thus, many scaffold-based research activities have been done to develop new materials, structures and fabrication technologies to mimic native meniscus for cell attachment and subsequent tissue development, and restore functionalities of injured meniscus for long-term effects...
January 3, 2017: Materials
https://www.readbyqxmd.com/read/28768432/effects-of-surgical-factors-on-cartilage-can-be-detected-using-quantitative-magnetic-resonance-imaging-after-anterior-cruciate-ligament-reconstruction
#12
Keiko Amano, Alan K Li, Valentina Pedoia, Matthew F Koff, Aaron J Krych, Thomas M Link, Hollis Potter, Scott Rodeo, Xiaojuan Li, C Benjamin Ma, Sharmila Majumdar
BACKGROUND: Quantitative magnetic resonance (qMR) can be used to measure macromolecules in tissues and is a potential method of observing early cartilage changes in the development of posttraumatic osteoarthritis. Hypothesis/Purpose: We hypothesized that specific patient and surgical factors affecting cartilage matrix composition after anterior cruciate ligament (ACL) reconstruction (ACLR) can be detected using T1ρ and T2 relaxation times. Our purpose was to demonstrate this ability in a multicenter feasibility study...
April 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28765605/the-potential-of-using-semitendinosus-tendon-as-autograft-in-rabbit-meniscus-reconstruction
#13
Chenxi Li, Xiaoqing Hu, Qingyang Meng, Xin Zhang, Jingxian Zhu, Linghui Dai, Jin Cheng, Mingjin Zhong, Weili Shi, Bo Ren, Jiying Zhang, Xin Fu, Xiaoning Duan, Yingfang Ao
Since transplantation of meniscal allograft or artificial menisci is limited by graft sources and a series of adverse events, substitution for meniscus reconstruction still needs to be explored. Natural biomaterials, which can provide a unique 3-D microenvironment, remain a promising alternative for tissue engineering. Among them, autograft is a preferred option for its safety and excellent biocompatibility. In this study, we utilized semitendinosus tendon autograft in meniscus reconstruction to investigate its fibrochondrogenic metaplasticity potential and chondroprotective effect...
August 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28765141/meniscal-resection-may-not-benefit-patients-with-traumatic-meniscal-tears
#14
Raine Sihvonen
No abstract text is available yet for this article.
August 1, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28763519/effects-of-nandrolone-decanoate-on-time-to-consolidation-of-bone-defects-resulting-from-osteotomy-for-tibial-tuberosity-advancement
#15
Danilo R C Marques, Danilo Marques, Jose F Ibanez, Itallo B Freitas, Ana C Hespanha, Juliana F Monteiro, Mayara Eggert, Amanda Becker
STUDY DESIGN: Experimental study. OBJECTIVE: The aim of this study was to evaluate the effect of nandrolone decanoate (ND) on the time taken for bone consolidation in dogs undergoing tibial tuberosity advancement surgery (TTA). MATERIALS AND METHODS: Seventeen dogs that underwent TTA surgery were randomly divided into two groups: group C (TTA; 9 stifles), and group TTA+ND (TTA and systemic administration of ND; 8 stifles). Three observers (two radiologists and an orthopaedic surgeon), assessed bone consolidation by visual inspection of serial radiographs at intervals of 21 days following surgery...
August 1, 2017: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/28760132/ulna-fracture-and-medial-meniscal-tear-resulting-from-dog-related-injuries
#16
O Şahap Atik, Mustafa Odluyurt, Efkan Özcan, Serkan Savlık
In this article, we present two middle-aged female patients with ulna fracture or medial meniscal tear resulting from dog-related injuries, which are not common. Both patients mentioned that pain started after their dogs pulled away their collar ropes strongly and suddenly. Both patients had postmenopausal osteoporosis and degenerative osteoarthritis. For this reason, ulna fracture and meniscus tear had developed with low-energy trauma resulting from dog-related injuries.
August 2017: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/28757192/delivery-of-epidermalgrowthfactor-receptor-inhibitor-via-a-customized-collagen-scaffold-promotes-meniscal-defect-regeneration-in-a-rabbit-model
#17
Zongyou Pan, Yan Wu, Xiaolei Zhang, Qianbao Fu, Jun Li, Yang Yang, Dongsheng Yu, Yuzi Xu, Xiaolang Lu, Heng Sun, Xianzhu Zhang, Boon Chin Heng, Varitsara Bunpetch, Shufang Zhang, Hongwei Ouyang
Meniscal injury is one of the most common knee joint injuries, which remains an intractable challenge in clinical practice to date. Aberrant epidermalgrowthfactor receptor (EGFR) activation levels in both human and mice menisci following injury, prompted us to investigate the functional role of EGFR by utilizing an inducible cartilage-specific EGFR-deficient mouse model. We demonstrated that conditional EGFR deletion in mice resulted in increased partial meniscectomy-induced ECM production within the meniscus, which is comparable to utilization of the small molecule EGFR inhibitor, gefitinib, to block EGFR activity...
July 27, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28754246/a-contact-pressure-analysis-comparing-an-all-inside-and-inside-out-surgical-repair-technique-for-bucket-handle-medial-meniscus-tears
#18
Daniel Cole Marchetti, Brian M Phelps, Kimi D Dahl, Erik L Slette, Jacob D Mikula, Grant J Dornan, Gabriella Bucci, Travis Lee Turnbull, Steven B Singleton
PURPOSE: To directly compare effectiveness of the inside-out and all-inside medial meniscal repair techniques in restoring native contact area and contact pressure across the medial tibial plateau at multiple knee flexion angles. METHODS: Twelve male, nonpaired (n = 12), fresh-frozen human cadaveric knees underwent a series of 5 consecutive states: (1) intact medial meniscus, (2) MCL tear and repair, (3) simulated bucket-handle longitudinal tear of the medial meniscus, (4) inside-out meniscal repair, and (5) all-inside meniscal repair...
July 25, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28753397/lateral-meniscal-allograft-transplant-via-a-medial-approach-leads-to-less-extrusion
#19
Nam-Hong Choi, Jeong-Ki Choi, Bong-Seok Yang, Doe-Hyun Lee, Brian N Victoroff
BACKGROUND: Accurate positioning of the bony bridge is crucial to prevent extrusion of meniscal allografts after transplant. However, oblique or lateralized placement of the bony bridge of the lateral meniscal allograft may occur due to technical error or a limited visual field. The patellar tendon may be an obstacle to approaching the anterior horn of the lateral meniscus, resulting in a laterally placed allograft. Therefore, lateral meniscal transplant through a medial arthrotomy would be an alternative approach...
July 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28748491/polyurethane-meniscal-scaffolds-lead-to-better-clinical-outcomes-but-worse-articular-cartilage-status-and-greater-absolute-meniscal-extrusion
#20
Young-Soo Shin, Hoon-Nyun Lee, Hyun-Bo Sim, Hyun-Jung Kim, Dae-Hee Lee
PURPOSE: Implantation of polyurethane (PU) meniscal scaffolds has become a popular procedure to provide a scaffold for vessel ingrowth and meniscal tissue regeneration in patients with partial meniscal defects. However, it is unclear whether PU meniscal scaffolds lead to better clinical and magnetic resonance imaging (MRI) outcomes post-operatively. This meta-analysis compared the clinical and MRI outcomes in patients with partial meniscal defects treated with PU meniscal scaffolds. METHODS: This meta-analysis reviewed all studies that assessed Lysholm score, International Knee Documentation Committee (IKDC) score, visual analogue scale (VAS) for pain, Tegner score, Knee Injury and Osteoarthritis Outcomes Score (KOOS), articular cartilage (AC), absolute meniscal extrusion (AME), morphology and size (MS), signal intensity (SI) of meniscal implant, and interface of the implant-residual meniscus complex (IIRMC) in patients with partial meniscal defects treated with PU meniscal scaffolds...
July 26, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
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