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Ravi S Hira, Larry S Dean
Provisional use of rotational atherectomy (RA) is indicated for procedural success in heavily calcified lesions. In the current study, RA use at three high volume percutaneous coronary intervention (PCI) centers between 2005 and 2013 was 1.4%. MACE rate was 17.8% at median follow-up of 22 months. Peripheral vascular disease (PVD), diabetes mellitus (DM), acute coronary syndrome (ACS), and SYNTAX > 23 were found to be independently associated with MACE. With increasing complexity of disease and SYNTAX score, there is usually an increase in severity of calcification and need for atherectomy...
October 2016: Catheterization and Cardiovascular Interventions
Tobias Hollmer, Winfried Petry
(99)Mo is the most widely used radioactive isotope in nuclear medicine. Its main production route is the fission of uranium. A major challenge for a reliable supply is the conversion from highly enriched uranium (HEU) to low enriched uranium (LEU). A promising candidate to realize this conversion is the cylindrical LEU irradiation target. The target consists of a uranium foil encapsulated between two coaxial aluminum cladding cylinders. This target allows a separate processing of the irradiated uranium foil and the cladding when recovering the (99)Mo...
October 6, 2016: Applied Radiation and Isotopes
J Baker
In this chapter, an overview of the heterogeneous group of functional voice disorders is given, including the psychogenic voice disorder (PVD) and hyperfunctional or muscle tension voice disorder (MTVD) subgroups. Reference is made to prevalence and demographic data, with empiric evidence for psychosocial factors commonly associated with the onset and maintenance of these disorders. Clinical features that distinguish between the different presentations of PVD and MTVD are described. While there are some shared characteristics, key differences between these two subgroups indicate that PVD more closely resembles the psychogenic movement disorders and a range of other functional neurologic disorders...
2017: Handbook of Clinical Neurology
David N Naumann, Clare Mellis, Shamus L G Husheer, Philip Hopkins, Jon Bishop, Mark J Midwinter, Sam D Hutchings
BACKGROUND: Despite over a decade of research and technological advances, sublingual microcirculatory monitoring has not yet reached clinical utility. Offline analysis is time consuming and occurs away from the patient. A system to assess the microcirculation at the point of care is desirable. We present a novel 5-point grading system (the point of care microcirculation (POEM) scoring system) that can be used at the point of care during non-invasive sublingual microcirculatory monitoring...
September 30, 2016: Critical Care: the Official Journal of the Critical Care Forum
Yan Wu, Meng-Yu He, Jian-Kui Ye, Shu-Ying Ma, Wen Huang, Yong-Yue Wei, Hui Kong, Hong Wang, Xiao-Ning Zeng, Wei-Ping Xie
Accumulating data, including those from our laboratory, have shown that the opening of ATP-sensitive potassium channels (KATP ) plays a protective role in pulmonary vascular diseases (PVD). As maintainers of the endothelial framework, endothelial colony-forming cells (ECFCs) are considered excellent candidates for vascular regeneration in cases of PVD. Although KATP openers (KCOs) have been demonstrated to have beneficial effects on endothelial cells, the impact of KATP on ECFC function remains unclear. Herein, this study investigated whether there is a distribution of KATP in ECFCs and what role KATP play in ECFC modulation...
October 6, 2016: Journal of Cellular and Molecular Medicine
Wei Zou, Ao Shen, Xintong Dong, Madina Tugizova, Yang K Xiang, Kang Shen
Ligand receptor interactions instruct axon guidance during development. How dendrites are guided to specific targets is less understood. The C. elegans PVD sensory neuron innervates muscle-skin interface with its elaborate dendritic branches. Here, we found that LECT-2, the ortholog of leukocyte cell-derived chemotaxin-2 (LECT2), is secreted from the muscles and required for muscle innervation by PVD. Mosaic analyses showed that LECT-2 acted locally to guide the growth of terminal branches. Ectopic expression of LECT-2 from seam cells is sufficient to redirect the PVD dendrites onto seam cells...
October 5, 2016: ELife
José Andonegui, José Ramón Maya, Marta Echeverría, Araceli Alcaine
A 78-year-old man complained of bilateral visual acuity loss. Optical coherence tomography examination showed bilateral macular schisis with fluid accumulation in the external retinal layers without vitreous traction. Fundus examination and fluorescein angiography were normal in both eyes. Both eyes were treated by phacoemulsification, intraocular lens implantation, and vitrectomy without laser, gas exchange, or retinal fenestration. Slow and progressive fluid resorption and improvement in VA were observed in both eyes...
2016: GMS Ophthalmol Cases
Gianna Camiciottoli, Francesca Bigazzi, Chiara Magni, Viola Bonti, Stefano Diciotti, Maurizio Bartolucci, Mario Mascalchi, Massimo Pistolesi
BACKGROUND: In addition to lung involvement, several other diseases and syndromes coexist in patients with chronic obstructive pulmonary disease (COPD). Our purpose was to investigate the prevalence of idiopathic arterial hypertension (IAH), ischemic heart disease, heart failure, peripheral vascular disease (PVD), diabetes, osteoporosis, and anxious depressive syndrome in a clinical setting of COPD outpatients whose phenotypes (predominant airway disease and predominant emphysema) and severity (mild and severe diseases) were determined by clinical and functional parameters...
2016: International Journal of Chronic Obstructive Pulmonary Disease
Ariel Fredrick, Bradley A Erickson, Kristian Stensland, Alex J Vanni
INTRODUCTION AND OBJECTIVES: Bulbar urethroplasty outcomes studies have shown low, but significant, rates of post- void dribbling (PVD) and ejaculatory dysfunction. The bulbospongiosus muscle is involved with expulsion of seminal fluid and urine from the bulbar urethra, and thus we hypothesized that performing urethroplasty utilizing a technique that does not split the muscle may result in better post-operative patient reported ejaculatory function (EF) and less PVD. METHODS: We performed a multi-institutional matched, case-control analysis comparing men who underwent a bulbospongiosus sparing (BS) technique to men that had undergone the traditional non-bulbospongiosus sparing (non-BS) technique...
September 26, 2016: Journal of Urology
Kizhakkepowathial Nair Unni, Prakasan Priji, Sreedharan Sajith, Panichikkal Abdul Faisal, Karippayi Mattil Shainy, Abraham Joseph, Moolath Girish Babu, Sailas Benjamin
Employing fluorescent quenching mechanism, type 2 pyoverdine (PVD) purified from Pseudomonas aeruginosa strain BUP2 (new strain isolated from the rumen of Malabari goat) was used as a simple, convenient and inexpensive tool for the rapid detection of Fe and Cu ions in contaminated drinking water samples. The fluorescence emitted at λ460 by PVD (in sterile water), mounted on a glass slide was efficiently quenched by the ions of heavy metals like Fe and Cu. The fluorescence quenching effect of PVD was monitored using UV trans-illuminator, and subsequently quantified and confirmed by spectrofluorimetry...
September 23, 2016: Journal of Microbiology and Biotechnology
Tammy Hod, Alexander S Goldfarb-Rumyantzev, Bhanu K Patibandla, Akshita Narra, Robert S Brown
BACKGROUND: In patients with failure of an initial arteriovenous fistula (AVF), a subsequent vascular access is needed before hemodialysis (HD) initiation. METHODS: To assess the optimal access strategy after a failed AVF, we linked data from the US Renal Data System with Medicare claims data identifying 21,436 patients ≥ 67 years old who started HD between January 1, 2005, and December 31, 2008, with an AVF placed as their first predialysis access. Of the 10,568 subjects whose AVF failed, 1,796 patients had an AVF placed as a second access predialysis (AVF2 group) and 399 patients had an arteriovenous graft placed as a second access predialysis (AVG2 group)...
November 2016: Clinical Nephrology
P J Chung, J S Lee, S Tam, A Schwartzman, M O Bernstein, L Dresner, A Alfonso, G Sugiyama
PURPOSE: Anterior abdominal wall hernias are among the most commonly encountered surgical disease. We sought to identify risk factors that are associated with 30-day postoperative mortality following emergent abdominal wall hernia repair using the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database. METHODS: A retrospective analysis of data from the ACS NSQIP from 2005 to 2010 was performed. Patients were selected using Current Procedural Terminology (CPT) and International Classification of Disease 9 Clinical Modification (ICD9) codes for the repair of inguinal, femoral, umbilical, epigastric, ventral, or incisional hernias that were incarcerated, obstructed, strangulated, or gangrenous...
September 16, 2016: Hernia: the Journal of Hernias and Abdominal Wall Surgery
Giancarlo A Garcia, Matin Khoshnevis, Kenneth M P Yee, Jeanne Nguyen-Cuu, Justin H Nguyen, J Sebag
PURPOSE: To evaluate the effect of posterior vitreous detachment (PVD) on contrast sensitivity function (CSF) in previously normal eyes, with the hypothesis that PVD reduces CSF. DESIGN: Prospective observational case series. METHODS: At a single clinical practice 28 eyes were evaluated: 8 eyes of 8 adults (mean age=54.4 ± 10.1 years; range=39 to 68) with normal CSF documented by Freiburg Acuity Contrast Testing (Weber index: %W) who subsequently experienced PVD, as confirmed by ultrasonography and OCT; 8 fellow eyes without PVD; and 12 control eyes: 9 eyes with PVD in patients who chose observation and 3 fellow eyes without PVD...
September 12, 2016: American Journal of Ophthalmology
Sarah A Vannier, Natalie O Rosen, Sean P Mackinnon, Sophie Bergeron
Provoked vestibulodynia (PVD) is a recurrent, genito-pelvic pain condition that affects 8-12 % of women and has negative implications for sexual and relationship functioning. Many women with PVD report avoiding physical affection because they are concerned that affectionate behavior will lead to painful sexual activity. In community samples, physical affection is associated with improved sexual and relational well-being; however, no research has assessed the influence of physical affection on well-being in women with PVD...
September 12, 2016: Archives of Sexual Behavior
Arvind Dabass, Evelyn O Talbott, Richard A Bilonick, Judith R Rager, Arvind Venkat, Gary M Marsh, Chunzhe Duan, Tao Xue
BACKGROUND: U.S. urban air quality has improved dramatically over the past decades. We evaluated acute effects of fine particulate matter (PM2.5) on cardiovascular (CVD) mortality among residents of Allegheny County in SW Pennsylvania (1999-2011) using spatio-temporal modeling of air pollutants (AP) to reduce misclassification error in exposure assessment. METHODS: Spatio-temporal kriging of daily PM2.5 and ozone (O3) was used to produce daily exposure estimates at the residence ZIP code...
August 31, 2016: Environmental Research
Gabrielle McNicoll, Serena Corsini-Munt, Natalie O Rosen, Pierre McDuff, Sophie Bergeron
Provoked vestibulodynia (PVD) is a recurrent idiopathic vulvo-vaginal pain associated with negative sexual and psychological consequences. Facilitative partner responses to pain are currently receiving empirical attention because they are positively associated with women's sexual outcomes. However, the mechanisms through which facilitative responses to pain are associated with these outcomes have not been examined. One potential mechanism is sexual assertiveness, which has been found to be associated with better sexual function and satisfaction in women with PVD...
September 1, 2016: Journal of Sex & Marital Therapy
Andrea Carsetti, Hollmann D Aya, Silvia Pierantozzi, Simone Bazurro, Abele Donati, Andrew Rhodes, Maurizio Cecconi
Analysis of the microcirculation is currently performed offline, is time consuming and operator dependent. The aim of this study was to assess the ability and efficiency of the automatic analysis software CytoCamTools 1.7.12 (CC) to measure microvascular parameters in comparison with Automated Vascular Analysis (AVA) software 3.2. 22 patients admitted to the cardiothoracic intensive care unit following cardiac surgery were prospectively enrolled. Sublingual microcirculatory videos were analysed using AVA and CC software...
September 1, 2016: Journal of Clinical Monitoring and Computing
Beatrice P Concepcion, Rachel C Forbes, Aihua Bian, Heidi M Schaefer
Background. The kidney transplant evaluation process for older candidates is complex due to the presence of multiple comorbid conditions. Methods. We retrospectively reviewed patients ≥60 years referred to our center for kidney transplantation over a 3-year period. Variables were collected to identify reasons for patients being turned down and to determine the number of unnecessary tests performed. Statistical analysis was performed to estimate the association between clinical predictors and listing status...
2016: Journal of Transplantation
Grace Joshy, Manish Arora, Rosemary J Korda, John Chalmers, Emily Banks
OBJECTIVE: To investigate the relationship between oral health and incident hospitalisation for ischaemic heart disease (IHD), heart failure (HF), ischaemic stroke and peripheral vascular disease (PVD) and all-cause mortality. DESIGN: Prospective population-based study of Australian men and women aged 45 years or older, who were recruited to the 45 and Up Study between January 2006 and April 2009; baseline questionnaire data were linked to hospitalisations and deaths up to December 2011...
2016: BMJ Open
Wei Fang, Jiu-Ke Li, Xiao-Hong Jin, Yuan-Min Dai, Yu-Min Li
AIM: To evaluate predictive factors for postoperative visual function of primary chronic rhegmatgenous retinal detachment (RRD) after sclera buckling (SB). METHODS: Totally 48 patients (51 eyes) with primary chronic RRD were included in this prospective interventional clinical cases study, which underwent SB alone from June 2008 to December 2014. Age, sex, symptoms duration, detached extension, retinal hole position, size, type, fovea on/off, proliferative vitreoretinopathy (PVR), posterior vitreous detachment (PVD), baseline best corrected visual acuity (BCVA), operative duration, follow up duration, final BCVA were measured...
2016: International Journal of Ophthalmology
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