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https://www.readbyqxmd.com/read/28708815/incidence-of-posterior-vitreous-detachment-after-femtosecond-lasik-compared-with-microkeratome-lasik
#1
Moataz Hamed Osman, Noha Mahmoud Khalil, Mohamed-Sameh El-Agha
PURPOSE: To compare the incidence of posterior vitreous detachment (PVD) after femtosecond and microkeratome laser in situ keratomileusis (LASIK). SETTING: Rowad Correction Centre, Cairo, Egypt (a private center affiliated to Cairo University). DESIGN: Prospective, nonrandomized comparative unmasked study. METHODS: The study was conducted at a single laser center. Eligible patients chose between femtosecond and microkeratome LASIK after appropriate counseling...
July 13, 2017: Cornea
https://www.readbyqxmd.com/read/28707602/ginkgo-biloba-extract-in-vascular-protection-molecular-mechanisms-and-clinical-applications
#2
Jinfan Tian, Yue Liu, Keji Chen
Background Leaves of Ginkgo biloba, a "living fossil," have been used as traditional herbal medicine for hundreds of years in China. Currently, its application in vascular protection is gaining much attention. Methods In this manuscript, preclinical studies were reviewed to discuss various mechanisms underlying the vascular protection by Ginkgo biloba extract (GBE). Additionally, we reviewed clinical studies to present the application of GBE in the ischaemic disease. Results GBE, a commonly used as a dietary supplement, has been shown to act as an antioxidant and free-radical scavenger, a membrane stabilizer, an inhibitor of the platelet-activating factor, a vasodilator, and a regulator of metabolism...
July 12, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28697925/variable-expressivity-of-a-founder-mutation-in-the-eif2ak4-gene-in-hereditary-pulmonary-veno-occlusive-disease-and-its-impact-on-survival
#3
Paula Navas Tejedor, Julián Palomino Doza, Jair Antonio Tenorio Castaño, Ana Belén Enguita Valls, José Julián Rodríguez Reguero, Amaya Martínez Meñaca, Ignacio Hernández González, Héctor Bueno Zamora, Pablo Daniel Lapunzina Badía, Pilar Escribano Subías
INTRODUCTION AND OBJECTIVES: Hereditary pulmonary veno-occlusive disease (PVOD) has been associated with biallelic mutations in EIF2AK4 with the recent discovery of a founder mutation in Iberian Romani patients with familial PVOD. The aims of this study were phenotypical characterization and survival analysis of Iberian Romani patients with familial PVOD carrying the founder p.Pro1115Leu mutation in EIF2AK4, according to their tolerance to pulmonary vasodilators (PVD). Familial genetic screening was conducted, as well as assessment of sociocultural determinants with a potential influence on disease course...
July 8, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28688714/restenosis-predictors-after-carotid-angioplasty-and-stenting-and-its-influence-on-procedure-durability-single-center-experience
#4
Ossama Y Mansour, Abdelrahman Ibrahim, Mostafa Talaat
BACKGROUND: This article reports our experience regarding in-stent restenosis in the carotid arteries with special focus was given to angiographic morphology and clinical predictors of in-stent restenosis. METHODS: Between July 2008 and August 2011, 245 carotid angioplasty and stenting procedures were performed in 243 patients (172 men and 71 women). Stenting for de novo stenoses was performed in 214 (87.3%) carotid arteries, and 31 (12.7%) vessels were treated because of postsurgical restenosis...
July 5, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28685112/growth-structure-and-stability-of-sputter-deposited-mos2-thin-films
#5
Reinhard Kaindl, Bernhard C Bayer, Roland Resel, Thomas Müller, Viera Skakalova, Gerlinde Habler, Rainer Abart, Alexey S Cherevan, Dominik Eder, Maxime Blatter, Fabian Fischer, Jannik C Meyer, Dmitry K Polyushkin, Wolfgang Waldhauser
Molybdenum disulphide (MoS2) thin films have received increasing interest as device-active layers in low-dimensional electronics and also as novel catalysts in electrochemical processes such as the hydrogen evolution reaction (HER) in electrochemical water splitting. For both types of applications, industrially scalable fabrication methods with good control over the MoS2 film properties are crucial. Here, we investigate scalable physical vapour deposition (PVD) of MoS2 films by magnetron sputtering. MoS2 films with thicknesses from ≈10 to ≈1000 nm were deposited on SiO2/Si and reticulated vitreous carbon (RVC) substrates...
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/28684537/pomalidomide-bortezomib-and-dexamethasone-pvd-for-patients-with-relapsed-lenalidomide-refractory-multiple-myeloma
#6
Jonas Paludo, Joseph R Mikhael, Betsy R LaPlant, Alese E Halvorson, Shaji Kumar, Morie A Gertz, Suzanne R Hayman, Francis K Buadi, Angela Dispenzieri, John A Lust, Prashant Kapoor, Nelson Leung, Stephen J Russell, David Dingli, Ronald S Go, Yi Lin, Wilson I Gonsalves, Rafael Fonseca, P Leif Bergsagel, Vivek Roy, Taimur Sher, Asher A Chanan-Khan, Sikander Ailawadhi, A Keith Stewart, Craig B Reeder, Paul G Richardson, S Vincent Rajkumar, Martha Q Lacy
This phase I/II trial evaluated the maximum tolerated doses (MTD), safety and efficacy of pomalidomide, bortezomib and dexamethasone (PVD) combination in patients with relapsed, lenalidomide refractory, MM. In the phase I, dose level 1 consisted of pomalidomide 4mg PO days 1-21, bortezomib 1.0 mg/m(2) IV or SQ days 1,8,15,22 and dexamethasone 40mg PO days 1,8,15,22 given every 28 days. Bortezomib was increased to 1.3 mg/m(2) for dose level 2 and adopted in the phase 2 expansion cohort. We describe the results of 50 patients...
July 6, 2017: Blood
https://www.readbyqxmd.com/read/28680562/addressing-the-challenges-of-phenotyping-pediatric-pulmonary-vascular-disease
#7
REVIEW
Kara N Goss, Allen D Everett, Peter M Mourani, Christopher D Baker, Steven H Abman
Pediatric pulmonary vascular disease (PVD) and pulmonary hypertension (PH) represent phenotypically and pathophysiologically diverse disease categories, contributing substantial morbidity and mortality to a complex array of pediatric conditions. Here, we review the multifactorial nature of pediatric PVD, with an emphasis on improved recognition, phenotyping, and endotyping strategies for pediatric PH. Novel tailored approaches to diagnosis and treatment in pediatric PVD, as well as the implications for long-term outcomes, are highlighted...
March 2017: Pulmonary Circulation
https://www.readbyqxmd.com/read/28677894/metallic-conductive-nanowires-elaborated-by-pvd-metal-deposition-on-suspended-dna-bundles
#8
Christophe Brun, Pierre-Henri Elchinger, Guillaume Nonglaton, Cheikh Tidiane-Diagne, Raluca Tiron, Aurélie Thuaire, Didier Gasparutto, Xavier Baillin
Metallic conductive nanowires (NWs) with DNA bundle core are achieved, thanks to an original process relying on double-stranded DNA alignment and physical vapor deposition (PVD) metallization steps involving a silicon substrate. First, bundles of DNA are suspended with a repeatable process between 2 µm high parallel electrodes with separating gaps ranging from 800 nm to 2 µm. The process consists in the drop deposition of a DNA lambda-phage solution on the electrodes followed by a naturally evaporation step...
July 5, 2017: Small
https://www.readbyqxmd.com/read/28671764/the-evaluation-of-the-non-invasive-msct-based-indices-for-the-diagnosis-and-prognosis-prediction-of-liver-cirrhosis
#9
Ling-Mei Feng, Shu-Juan Lei, Xin Zeng, Pei-Qin Wang, Ru-Tan Chen, Jian Wang, Xia Sheng, Pei-Mei Shi, Zong-Li Yuan, Wei-Fen Xie
PURPOSE: It is necessary to develop feasible and reliable non-invasive methods to determine liver function and predict complications in patients with liver cirrhosis. The aim of this study was to determine the value of CT-based easily available parameters in evaluating the severity of cirrhosis and predicting complications in Chinese cirrhotic patients. METHODS: CT-based morphological indices were determined in 167 cirrhotic patients and 244 healthy volunteers. The correlation of morphological indices with the Child-Pugh score/grade and complication of cirrhosis was analysed by Spearman correlation analysis...
July 3, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28657897/a-retrospective-review-of-adverse-events-related-to-diabetic-foot-ulcers
#10
Latricia Allen, Gail Powell-Cope, Alfred Mbah, Tatjana Bulat, Eni Njoh
The risk of adverse events (AEs) such as infection and amputation related to diabetic foot ulcers (DFUs) has been studied, but less is known about rate of other AEs such as falls. As part of a quality improvement project, AEs in veterans with diabetes mellitus (DM) with and without a DFU were examined. Demographic data including ICD-9 codes, AEs, and comorbidities for all patients with a diagnosis of DM and/or DFU treated between 2009 and 2014 at the James A. Haley Veterans' Hospital, Tampa, FL, were reviewed retrospectively utilizing the Corporate Data Warehouse (CDW) database...
June 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/28657093/investigation-of-the-shock-induced-chemical-reaction-sicr-in-ni-al-nanoparticle-mixtures
#11
Yongnan Xiong, Shifang Xiao, Huiqiu Deng, Wenjun Zhu, Wangyu Hu
Molecular dynamics (MD) simulations are used to investigate the shock-compression response of Ni + Al spherical nanoparticles arranged in a NaCl-like structure. The deformation and reaction characteristics are studied from the particle level to the atomic scale at various piston velocities. Shock-induced chemical reactions (SICRs) occur during non-equilibrium processes, accompanied by a sharp rise in temperature and rapid mixing of atoms. The preferentially deformed Al particles form a high-speed mass flow relative to the Ni at the shock front, which impinges on the Ni particles, and mixing of Ni and Al atoms occurs immediately at the interface...
July 21, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28631403/-pseudomonas-protegens-pf-5-favors-self-produced-siderophore-over-free-loading-in-interspecies-competition-for-iron
#12
D Joseph Sexton, Rochelle C Glover, Joyce E Loper, Martin Schuster
Many microorganisms compete for extracellular iron using strain-specific chelators known as siderophores. The ferric-siderophore complex limits local access to iron because import requires a suitable cognate receptor. Interestingly, many species carry receptors that enable "cross-feeding" on heterologous siderophores made by neighboring organisms, although little is known about how this ubiquitous behavior is regulated. Here, we investigated the soil bacterium Pseudomonas protegens Pf-5, a strain remarkable for its ability to use dozens of heterologous siderophores...
June 19, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28631237/structural-characterization-of-pyoverdines-produced-by-pseudomonas-putida-kt2440-and-pseudomonas-taiwanensis-vlb120
#13
Matthias Baune, Yulin Qi, Karen Scholz, Dietrich A Volmer, Heiko Hayen
The previously unknown sequences of several pyoverdines (PVD) produced by a biotechnologically-relevant bacterium, namely, Pseudomonas taiwanensis VLB120, were characterized by high performance liquid chromatography (HPLC)-high resolution mass spectrometry (HRMS). The same structural characterization scheme was checked before by analysis of Pseudomonas sp. putida KT2440 samples with known PVDs. A new sample preparation strategy based on solid-phase extraction was developed, requiring significantly reduced sample material as compared to existing methods...
June 19, 2017: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://www.readbyqxmd.com/read/28630168/incidence-and-factors-associated-with-the-occurrence-of-pulmonary-vein-narrowing-after-cryoballoon-ablation
#14
Ryohsuke Narui, Michifumi Tokuda, Masato Matsushima, Ryota Isogai, Kenichi Tokutake, Kenichi Yokoyama, Mika Hioki, Keiichi Ito, Shin-Ichi Tanigawa, Seigo Yamashita, Keiichi Inada, Kenri Shibayama, Seiichiro Matsuo, Satoru Miyanaga, Kenichi Sugimoto, Michihiro Yoshimura, Teiichi Yamane
BACKGROUND: In contrast with traditional radiofrequency ablation, little is known about the influence of cryoballoon ablation on the morphology of pulmonary veins (PVs). We evaluated the influence of cryoballoon ablation on the PV dimension (PVD) and investigated the factors associated with a reduction of the PVD. METHODS AND RESULTS: Seventy-four patients who underwent cryoballoon ablation for paroxysmal atrial fibrillation were included in the present study. All subjects underwent contrast-enhanced computed tomography both before and at 3 months after the procedure...
June 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28625955/experiment-of-vitreous-liquefaction-induced-by-c3f8
#15
Jing Wang, Qiuming Li
To investigate the effect and safety of vitreous liquefaction induced by C3F8 (an inert gas) injected into vitreous cavit of rabbit eyes. 24 rabbits (48 eyes) were randomly divided into four groups, named group A, group B, group C and group D, with 6 rabbits in each group. The right eye in each rabbit was taken as the experimental eye while the left as the control eye. The experimental eyes in group A were injected with 0.1mL disinfectant air; the experimental eyes in group B, group C and group D were all injected with C3F8 0...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28620965/determination-of-retinal-surface-area
#16
Manbir Nagra, Bernard Gilmartin, Ngoc Jade Thai, Nicola S Logan
Previous attempts at determining retinal surface area and surface area of the whole eye have been based upon mathematical calculations derived from retinal photographs, schematic eyes and retinal biopsies of donor eyes. 3-dimensional (3-D) ocular magnetic resonance imaging (MRI) allows a more direct measurement, it can be used to image the eye in vivo, and there is no risk of tissue shrinkage. The primary purpose of this study is to compare, using T2-weighted 3D MRI, retinal surface areas for superior-temporal (ST), inferior-temporal (IT), superior-nasal (SN) and inferior-nasal (IN) retinal quadrants...
June 16, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28599823/neuropathy-and-presence-of-emotional-distress-and-depression-in-longstanding-diabetes-results-from-the-canadian-study-of-longevity-in-type-1-diabetes
#17
Johnny-Wei Bai, Leif E Lovblom, Marina Cardinez, Alanna Weisman, Mohammed A Farooqi, Elise M Halpern, Genevieve Boulet, Devrim Eldelekli, Julie A Lovshin, Yuliya Lytvyn, Hillary A Keenan, Michael H Brent, Narinder Paul, Vera Bril, David Z I Cherney, Bruce A Perkins
AIM: To determine the association of neuropathy and other complications with emotional distress and depression among patients with longstanding type 1 diabetes (T1DM). METHODS: Canadians with ≥50years of T1DM completed a questionnaire including assessment of distress and depression by the Problem Areas in Diabetes Scale (PAID) and Geriatric Depression Scale (GDS), respectively. Complications were determined using the Michigan Neuropathy Screening Instrument (Questionnaire Component), fundoscopy reports, renal function tests, and self-reported peripheral-(PVD) and cardiovascular (CVD) disease...
May 10, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28598042/peripheral-vascular-disease-in-patients-with-diabetic-foot-ulcers-an-emerging-trend-a-prospective-study-from-north-india
#18
Supriya Bajaj, Amit Mahajan, Sumit Grover, Vijay Mahajan, Pankaj Goyal, Vikram Kumar Gupta
BACKGROUND: Diabetic foot ulcer is one of the chronic complications of diabetes mellitus (DM) with 25% of patients with diabetes developing a foot ulcer during their lifetime leading to amputation. Diabetic foot is classified into 2 main types: neuropathic ulcers (NPU) and neuro-ischemic ulcer (NIU) where in addition to neuropathy peripheral vascular disease (PVD) is also present. AIMS: We aimed to a) assess the prevalence of Peripheral vascular disease (PVD) in patients of type 2 diabetes mellitus (T2DM) presenting with New Diabetic Foot ulcers (DFU)...
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28598041/the-double-trouble-pvd-and-peripheral-neuropathy-in-diabetes
#19
Mangesh Tiwaskar
No abstract text is available yet for this article.
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28587917/home-urodynamic-pressures-and-volume-measurement-for-the-neurogenic-bladder-initial-validation-study
#20
Guy Hidas, Tandis Soltani, John Billimek, Blake Selby, Maryellen S Kelly, Gordon McLorie, Elias Wehbi, Antoine E Khoury
AIMS: To evaluate the ability of a bladder pressure/volume diary (PVD) to identify patients at risk for elevated intravesical pressures. METHODS: Clean intermittent catheterization (CIC) dependent patients used ruler-based manometry to measure intravesical pressures prior to leakage or scheduled drainage at home. We prospectively collected clinical, urodynamic (UDS), and PVD data in patients with spina bifida who were optimized on anticholinergic therapy and on CIC...
June 3, 2017: Journal of Urology
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