keyword
MENU ▼
Read by QxMD icon Read
search

Crohn's:8

keyword
https://www.readbyqxmd.com/read/29780599/perioperative-blood-transfusion-is-associated-with-post-operative-infectious-complications-in-patients-with-crohn-s-disease
#1
Nan Lan, Luca Stocchi, Yi Li, Bo Shen
Background: We have previously demonstrated that blood transfusion (BT) was associated with post-operative complications in patients undergoing surgery for Crohn's disease (CD), based on our institutional data registry. The aim of this study was to verify the association between perioperative BT and infectious complications in CD patients enrolled in the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database. Methods: All CD patients undergoing surgery between 2005 and 2013 were identified from NSQIP...
May 2018: Gastroenterology Report
https://www.readbyqxmd.com/read/29770917/readmission-after-abdominal-surgery-for-crohn-s-disease-identification-of-high-risk-patients
#2
Diane Mege, Fabrizio Michelassi
BACKGROUND: Although many predictive factors for postoperative morbidity are known, few data are available about readmission after abdominal surgery for Crohn's disease (CD). The objective of this study is to identify predictive factors and high-risk patients for readmission after abdominal CD surgery. METHODS: All patients who underwent abdominal surgery for CD in one tertiary referral center between January 2004 and December 2016 were included. Patients who required readmission and those without were compared...
May 16, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29762265/link-between-celiac-disease-and-inflammatory-bowel-disease
#3
Ayesha Shah, Marjorie Walker, Daniel Burger, Neal Martin, Moritz von Wulffen, Natasha Koloski, Mike Jones, Nicholas J Talley, Gerald J Holtmann
GOAL: The aim of this analysis was to assess in patients with inflammatory bowel disease (IBD) the risk of celiac disease and in celiac disease patients the risk of IBD. BACKGROUND: Previous studies report a possible association between IBD and celiac disease; however, this link is controversial. STUDY: Using the search terms "inflammatory bowel disease" and "celiac disease," we identified initially 1525 publications. In total 27 studies met inclusion criteria...
May 14, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29761611/multidisciplinary-team-meetings-appear-to-be-effective-in-inflammatory-bowel-disease-management-an-audit-of-process-and-outcomes
#4
Mutaz Ferman, Amanda H Lim, Monowar Hossain, Glenn W Siow, Jane M Andrews
BACKGROUND: Multidisciplinary team meetings (MDTMs) have proven efficacy in cancer management. Whilst widely implemented in inflammatory bowel disease (IBD) care, their value is yet to be investigated. We reviewed the performance of MDTMs for IBD patients. METHODS: Retrospective review of MDTMs from March 2013 to July 2016. Each patient's first MDTM was considered. Data collected included: report production and location, disease factors, recommendation(s), implementation and barriers to implementation...
May 14, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29760546/thiopurines-are-negatively-associated-with-anthropometric-parameters-in-pediatric-crohn-s-disease
#5
Neera Gupta, Robert H Lustig, Cewin Chao, Eric Vittinghoff, Howard Andrews, Cheng-Shiun Leu
AIM: To determine the distribution of anthropometric parameter (AP)- z -scores and characterize associations between medications/serum biomarkers and AP- z -scores in pediatric Crohn's disease (CD). METHODS: CD patients [< chronological age (CA) 21 years] were enrolled in a cross-sectional study. Descriptive statistics were generated for participants' demographic characteristics and key variables of interest. Paired t -tests were used to compare AP- z -scores calculated based on CA (CA z -scores) and bone age (BA) (BA z -scores) for interpretation of AP's...
May 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29757772/systematic-analysis-of-annual-health-resource-utilization-and-costs-in-hospitalized-patients-with-inflammatory-bowel-disease-in-switzerland
#6
Alain Schoepfer, Stephan R Vavricka, Beat Brüngger, Oliver Reich, Eva Blozik, Caroline Bähler
BACKGROUND AND AIMS: Real-life data on health resource utilization and costs of hospitalized patients with inflammatory bowel disease are lacking in Switzerland. We aimed to assess health resource utilization and costs during a 1-year follow-up period starting with an index hospitalization. PATIENTS AND METHODS: On the basis of claims data of the Helsana health insurance group, health resource utilization was assessed and costs reimbursed by mandatory basic health insurance [in Swiss Francs (CHF); 1 CHF=0...
May 11, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29752571/w-e-w-roediger-causative-factors-of-ulcerative-colitis-and-crohn-s-disease-an-exploratory-guide-wakefield-press-2016-reprinted-2017-106-pp-isbn-978-174305-433-8
#7
Michael W Whitehouse
This monograph provides the background for new developments in gastroenterological pharmacology, particularly focussing on the two chronic inflammatory bowel diseases, ulcerative colitis (UC) and Crohn's disease (CD). These currently cause significant morbidity but largely elude satisfactory treatment. This is a challenge to drug designers and experimental physiologists alike. Their efforts will be much enhanced by further understanding the aspects of molecular pathogenesis and physiological dysregulation outlined in this valuable and timely survey...
May 11, 2018: Inflammopharmacology
https://www.readbyqxmd.com/read/29741667/the-impact-of-opioid-epidemic-trends-on-hospitalized-inflammatory-bowel-disease-patients
#8
Shirley Cohen-Mekelburg, Russell Rosenblatt, Stephanie Gold, Robert Burakoff, Akbar Waljee, Sameer Saini, Bruce R Schackman, Ellen Scherl, Carl Crawford
Background and Aims: Opioid use disorder (OUD) has become a public health crisis among patients with chronic disease. Inflammatory bowel disease (IBD) patients are high risk for OUD because they suffer from chronic relapsing-remitting pain.  We aimed to describe the prevalence and trends in OUD-related diagnoses among hospitalized IBD patients. Methods: A retrospective study was performed using weighted Nationwide Inpatient Sample data from 2005-2014. Adult IBD hospital visits and OUD-related diagnoses were identified using a previously published schema...
May 7, 2018: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29741603/phenotype-and-clinical-course-of-inflammatory-bowel-disease-with-co-existent-celiac-disease
#9
Chung Sang Tse, Parakkal Deepak, Jaime De La Fuente, Adam C Bledsoe, Joseph J Larson, Joseph A Murray, Konstantinos A Papadakis
Background and Aims: Inflammatory bowel diseases, principally Crohn's disease and ulcerative colitis, and celiac disease are among the most common immune-mediated gastrointestinal diseases. We aim to elucidate the clinical course and outcomes of patients with concomitant inflammatory bowel disease and celiac disease, a unique population that remains scarcely studied to date. Methods: A retrospective matched case-control study of adults with coexistent inflammatory bowel disease and celiac disease was performed at a tertiary referral institution in North America...
May 7, 2018: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29736839/stricturing-and-fistulizing-crohn-s-disease-is-associated-with-anti-tumor-necrosis-factor-induced-psoriasis-in-patients-with-inflammatory-bowel-disease
#10
Adam V Weizman, Robyn Sharma, N M Afzal, Wei Xu, Scott Walsh, Joanne M Stempak, Geoffrey C Nguyen, Ken Croitoru, A Hillary Steinhart, Mark S Silverberg
BACKGROUND: Paradoxical development of psoriasis in patients on anti-TNF agents has been increasingly reported. AIM: The aim was to characterize the prevalence and clinical characteristics of anti-TNF-associated psoriasis in a large cohort of inflammatory bowel disease patients. METHODS: Medical records of patients with Crohn's disease or ulcerative colitis treated with anti-TNF therapy at a single, tertiary IBD center were identified between 2004 and 2016...
May 8, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29727386/entyvio-lengthen-dose-interval-study-lengthening-vedolizumab-dose-interval-and-the-risk-of-clinical-relapse-in-inflammatory-bowel-disease
#11
Webber Chan, Nicole Lynch, Peter Bampton, Jeff Chang, Alvin Chung, Timothy Florin, David J Hetzel, Simon Jakobovits, Gregory Moore, Paul Pavli, Graham Radford-Smith, Lena Thin, Brandon Baraty, Craig Haifer, Yunki Yau, Rupert W L Leong
BACKGROUND: Vedolizumab (VDZ), an α4β7 anti-integrin antibody, is efficacious in the induction and maintenance of remission in ulcerative colitis (UC) and Crohn's disease (CD). In the GEMINI long-term safety study, enrolled patients received 4-weekly VDZ. Upon completion, patients were switched to 8-weekly VDZ in Australia. The clinical success rate of treatment de-escalation for patients in remission on VDZ has not been described previously. AIM: To determine the proportion of patients who relapsed after switching from 4 to 8-weekly VDZ, the mean time to relapse, and the recapture rate when switching back to 8-weekly dosing...
April 30, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29726939/the-effects-of-ustekinumab-on-health-related-quality-of-life-in-patients-with-moderate-to-severe-crohn-s-disease
#12
Bruce E Sands, Chenglong Han, Christopher Gasink, Douglas Jacobstein, Philippe Szapary, Long-Long Gao, Yinghua Lang, Stephan Targan, William J Sandborn, Brian G Feagan
Background and Aims: We assessed the effect of ustekinumab on health-related quality of life (HRQOL) in adults with Crohn's disease (CD). Methods: Patients with moderately-to-severely active CD and inadequate response or intolerance to tumor necrosis factor antagonists (UNITI1, N=741), or conventional therapy (UNITI-2, N=627) were randomized to placebo, ustekinumab 130 mg, or 6 mg/kg intravenous induction therapy. At Week 8, ustekinumab-treated responders (CDAI reduction≥100 or CDAI<150 points) were re-randomized to subcutaneous maintenance therapy (IM-UNITI, N=388) with placebo, ustekinumab 90mg q12w, or q8w for 44 additional weeks...
May 3, 2018: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29724301/-clinical-value-of-multi-slice-spiral-enhanced-ct-in-diagnosing-mild-digestive-tract-hemorrhage
#13
Xiao Ling Wen, Li Wang, Xiao Qin Song, Zhi Zhang, Xiao Fang Zhu, Shao Ping Wu
Objective To investigate the clinical value of multi-slice spiral CT(MSCT) in the diagnosis of mild digestive tract hemorrhage. Methods Thirty-five patients with mild gastrointestinal hemorrhage were examined by enhanced MSCT.CT signs were observed and compared with pathologic examination findings.Results Diseases in these 35 patients included gastric and duodenal ulcer and inflammation(n=4,11.4%),esophagogastric variceal rupture(n=7,20.0%),gastric carcinoma(n=3,8.6%),gastric stromal tumor(n=3,8.6%),gastric polyp(n=1,2...
April 28, 2018: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29722832/rising-incidence-of-intestinal-infections-in-inflammatory-bowel-disease-a-nationwide-analysis
#14
Grant E Barber, Steven Hendler, Philip Okafor, David Limsui, Berkeley N Limketkai
Background: Intestinal infections are common in patients with inflammatory bowel disease (IBD) and may mimic IBD flares. In this study, we estimate the changing incidence of intestinal infections among IBD hospitalizations and assess the impact of intestinal infections on key hospitalization metrics. Methods: The National Inpatient Sample (NIS) was analyzed for hospitalizations from IBD between 1998 and 2014. Intestinal infections were identified using ICD-9-CM codes, and incidence for each infection was calculated for Crohn's disease (CD) and ulcerative colitis (UC)...
May 2, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29721733/time-between-suspected-and-confirmed-diagnoses-of-crohn-s-disease-and-ulcerative-colitis-in-patients-followed-in-gastroenterological-practices-in-germany
#15
Karel Kostev, Marcel Konrad, Louis Jacob
AIMS: The goal of the present study was to analyze the time between suspected and confirmed diagnoses of Crohn's disease (CD) and ulcerative colitis (UC) in patients followed in gastroenterological practices in Germany. METHODS: The study included individuals who received a suspected diagnosis of CD or UC (index date) and were followed in 47 gastroenterological practices in Germany between January 2007 and December 2016. The main outcome measure of the study was the time between suspected and confirmed diagnoses of CD and UC...
May 2, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29718327/association-between-serum-infliximab-trough-concentrations-during-maintenance-therapy-and-biochemical-endoscopic-and-histologic-remission-in-crohn-s-disease
#16
Konstantinos Papamichael, Shana Rakowsky, Claudio Rivera, Adam S Cheifetz, Mark T Osterman
Background and aim: Objective and more rigorous therapeutic outcomes are emerging as novel targets in Crohn's disease (CD). We investigated the association between maintenance serum infliximab trough concentrations and biochemical, endoscopic, or histologic remission in CD. Methods: This retrospective multicenter study involved consecutive CD patients treated with infliximab who had a serum C-reactive protein (CRP) measured within 1 week or endoscopic evaluation within 12 weeks of therapeutic drug monitoring between January 2010 and June 2016...
April 28, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29718309/real-time-shear-wave-ultrasound-elastography-differentiates-fibrotic-from-inflammatory-strictures-in-patients-with-crohn-s-disease
#17
Yu-Jun Chen, Ren Mao, Xue-Hua Li Md, Qing-Hua Cao, Zhi-Hui Chen, Bao-Xian Liu, Shu-Ling Chen, Bai-Li Chen, Yao He, Zhi-Rong Zeng, Shomron Ben-Horin, Jordi Rimola, Florian Rieder, Xiao-Yan Xie, Min-Hu Chen
Background and aim: The distinction of intestinal fibrosis from inflammation in Crohn's disease (CD) associated strictures has important therapeutic implications. Ultrasound elastography is useful in evaluating the degree of fibrosis in liver, but there is little evidence whether it can assess fibrosis in the bowel. We determined whether shear-wave elastography (SWE), a novel modification of elastography, quantifying tissue stiffness, could differentiate between inflammatory and fibrotic components in strictures of patients with CD...
April 28, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29718223/outcomes-of-treatment-for-latent-tuberculosis-infection-in-patients-with-inflammatory-bowel-disease-receiving-biologic-therapy
#18
Guilherme P Ramos, Gregory Stroh, Badr Al-Bawardy, William A Faubion, Konstantinos A Papadakis, Patricio Escalante
Background: Treatment for latent tuberculosis infection (LTBI) is of particular concern in patients with inflammatory bowel disease (IBD) initiating biologic therapies to prevent tuberculosis (TB) reactivation. This study aimed to evaluate the effectiveness of LTBI treatment in IBD patients receiving biologic therapy. Methods: There was a retrospective review of all IBD patients diagnosed with LTBI following a tuberculin skin test (TST) and/or interferon gamma release assay (IGRA) and who received biologic therapy between 2002 and 2016...
April 26, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29702298/increased-risk-of-acute-myocardial-infarction-and-heart-failure-in-patients-with-inflammatory-bowel-diseases
#19
Satimai Aniwan, Darrell S Pardi, William J Tremaine, Edward V Loftus
BACKGROUND & AIMS: There are conflicting data as to whether inflammatory bowel diseases (IBD) increase risk for cardiovascular disease. We sought to examine the risk of acute myocardial infarction (AMI) and heart failure in patients with IBD. METHODS: We identified patients diagnosed with IBD in Olmsted County, Minnesota from 1980 through 2010 (n=736). For each patient, 2 individuals without IBD (controls, n=1472) were randomly selected, matched for age, sex, and index date of disease diagnosis...
April 24, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29697550/use-of-infliximab-biosimilar-versus-originator-in-a-paediatric-united-kingdom-inflammatory-bowel-disease-induction-cohort
#20
Neil Chanchlani, Kajal Mortier, Linda J Williams, Rafeeq Muhammed, Marcus K H Auth, Mike Cosgrove, Andrew Fagbemi, John Fell, Sonny Chong, Veena Zamvar, Warren Hyer, W Michael Bisset, Mary-Anne Morris, Astor Rodrigues, Sally G Mitton, Su Bunn, R Mark Beattie, Anne Willmott, David C Wilson, Richard K Russell
OBJECTIVES: To summarize short-term effectiveness, safety, and cost of using infliximab biosimilar (IFX-B) drugs, (Inflectra™ and Remsima™) compared to originator infliximab (IFX-O) (Remicade®) in biologic naive pediatric inflammatory bowel disease in the United Kingdom. METHODS: Prospective audit of patients starting anti-TNF therapy. Disease severity, response to treatment, and remission rate was measured by Pediatric Crohn's Disease Activity Index (PCDAI) and/or Physician Global Assessment (PGA)...
April 23, 2018: Journal of Pediatric Gastroenterology and Nutrition
keyword
keyword
53050
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"