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Lokesh K Narnoliya, Girija Kaushal, Sudhir P Singh, Rajender S Sangwan
BACKGROUND: Rose-scented geranium (Pelargonium sp.) is a perennial herb that produces a high value essential oil of fragrant significance due to the characteristic compositional blend of rose-oxide and acyclic monoterpenoids in foliage. Recently, the plant has also been shown to produce tartaric acid in leaf tissues. Rose-scented geranium represents top-tier cash crop in terms of economic returns and significance of the plant and plant products. However, there has hardly been any study on its metabolism and functional genomics, nor any genomic expression dataset resource is available in public domain...
January 13, 2017: BMC Genomics
Gökçe Şeker Karatoprak, Gamze Aydin, Berrak Altinsoy, Cevahir Altinkaynak, Müberra Koşar, Ismail Ocsoy
Herein, we report the biosynthesis of Ag NPs, for the first time, using identified antimicrobial molecules (gallic acid+apocynin) and (gallic acid+apocynin+quercetin) from the medicinal plant Pelargonium endlicherianum Fenzl. and dramatically enhanced antimicrobial activity. We also investigate the role of each molecule on formation Ag NPs and explain the increase in the antimicrobial activity of identified molecules mediated Ag NPs. The extraction protocols, 11% ethanol and 70% methanol, resulted in identification of different constituents of gallic acid+apocynin (M1) and gallic acid+apocynin+quercetin (M2) with respective concentrations...
February 2017: Enzyme and Microbial Technology
Mao-Lun Weng, Tracey A Ruhlman, Robert K Jansen
For species with minor inverted repeat (IR) boundary changes in the plastid genome (plastome), nucleotide substitution rates were previously shown to be lower in the IR than the single copy regions (SC). However, the impact of large-scale IR expansion/contraction on plastid nucleotide substitution rates among closely related species remains unclear. We included plastomes from 22 Pelargonium species, including eight newly sequenced genomes, and used both pairwise and model-based comparisons to investigate the impact of the IR on sequence evolution in plastids...
December 19, 2016: New Phytologist
S Duchow, R Dahlke, T Geske, W Blaschek, B Classen
No abstract text is available yet for this article.
December 2016: Planta Medica
Miryam Pérez-Cañamás, Marta Blanco-Pérez, Javier Forment, Carmen Hernández
Pelargonium line pattern virus (PLPV, Tombusviridae) normally establishes systemic, low-titered and asymptomatic infections in its hosts. This type of interaction may be largely determined by events related to RNA silencing, a major antiviral mechanism in plants. This mechanism is triggered by double or quasi double-stranded (ds) viral RNAs which are cut by DCL ribonucleases into virus small RNAs (vsRNAs). Such vsRNAs are at the core of the silencing process as they guide sequence-specific RNA degradation Host RNA dependent-RNA polymerases (RDRs), and particularly RDR6, strengthen antiviral silencing by promoting biosynthesis of secondary vsRNAs...
January 15, 2017: Virology
O Laccourreye, A Werner, L Laccourreye, P Bonfils
OBJECTIVES: To elucidate the benefits, pitfalls and risks of phytotherapy in the clinical practice of otorhinolaryngology. MATERIAL AND METHODS: The PubMed and Cochrane databases were searched using the following keywords: phytotherapy, phytomedicine, herbs, otology, rhinology, laryngology, otitis, rhinitis, laryngitis and otorhinolaryngology. Seventy-two articles (18 prospective randomized studies, 4 Cochrane analyses, 4 meta-analysis and 15 reviews of the literature) devoted to clinical studies were analyzed...
November 30, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
Karel Šmejkal, Veronika Rjašková
Medicinal plants are advantageously used in the treatment of respiratory tract diseases. Upper respiratory tract catarrh is one of the diseases associated with seasonal weakening of immunity, and therefore, plant drugs with a non-specific immunomodulation effect are often used. Such plants include, but are not limited to, Echinacea (Echinacea purpurea) and American ginseng (Panax quinquefolius). In combination with medicinal plants having antibacterial and antiseptic effects, such as thyme (Thymus vulgaris) and pelargonium (Pelargonium sidoides), they can constitute efficient help in the treatment of respiratory tract diseases, shorten the duration of the disease and reduce the need of antibiotic therapy...
2016: Ceská a Slovenská Farmacie
Rafael Pazinato, Andréia Volpato, Matheus D Baldissera, Roberto C V Santos, Dilmar Baretta, Rodrigo A Vaucher, Janice L Giongo, Aline A Boligon, Lenita Moura Stefani, Aleksandro Schafer Da Silva
The acaricidal effect of seven essential oils was examined in vitro against the cattle tick (Rhipicephalus microplus). Engorged female ticks were manually collected in farms of Southern Brazil and placed into petri dishes (n = 10) in order to test the following oils: juniper (Juniperus communis), palmarosa (Cymbopogon martinii), cedar (Cedrus atlantica), lemon grass (Cymbopogon citratus), ginger (Zingiber officinale), geranium (Pelargonium graveolens) and bergamot (Citrus aurantium var bergamia) at concentrations of 1%, 5%, and 10% each...
November 2016: Journal of Advanced Research
Mohaddese Mahboubi, Mohammad Mehdi Feizabadi, Tahereh Khamechian, Nastaran Kazempour, Mohsen Razavi Zadeh, Farhang Sasani, Mohsen Bekhradi
BACKGROUND: Staphylococcus aureus is one of the most causative organisms in the skin wound infections. Development of resistant S. aureus to current treatments in individuals with low immunity is a global concern. The aim of this study was to evaluate the efficacy of herbal formulation against skin wound infection. METHODS: The efficacy of herbal formulation containing Oliveria decumbens and Pelargonium graveolens essential oils was evaluated in comparison to mupirocin against Methicillin Resistant S...
September 2016: World Journal of Plastic Surgery
Mohamad Reza Lavasanijou, Hamid Reza Sohrabi, Mehrdad Karimi, Mohammad Ali Ashjazade, Mohammad Salajeghe, Hossein Farzineejadizadeh, Pouya Parsaei, Ali Elmamooz
No abstract text is available yet for this article.
October 2016: Wounds: a Compendium of Clinical Research and Practice
Andrzej M Fal, Frank Conrad, Karina Schönknecht, Hartwig Sievers, Anna Pawińska
THE AIM: The in-vitro antiviral activity of the "Virus Blocking Factor" (VBF), a combination of Pelargonium extract and Sambucus juice with addition of Betaglucan 1,3 / 1,6, Zincum gluconium, Acidum ascorbicum, was studied against human pathogenic viruses: Influenza A H1N1 (FluA H1N1), Rhinovirus B subtype 14 (HRV14), Respiratory Syncytial Virus (RSV), Parainfluenzavirus subtype 3 (Para 3), and Adenovirus C subtype 5 (Adeno 5). METHOD: Antiviral activity was assessed using plaque-reduction assays after adding the test substance post infection of the MDCK, HeLa and HEp-2 cells with the viruses...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Marija Vidović, Filis Morina, Ljiljana Prokić, Sonja Milić-Komić, Bojana Živanović, Sonja Veljović Jovanović
In this study we exposed variegated leaves of Pelargonium zonale to strong sunlight (>1100μmolm(-2)s(-1) of photosynthetically active radiation) with and without paraquat (Pq), with the aim to elucidate the mechanisms of H2O2 regulation in green and white tissues with respect to the photosynthetically-dependent generation of reactive oxygen species (ROS). Sunlight induced marked accumulation of H2O2 in the apoplast of vascular and (peri)vascular tissues only in green sectors. This effect was enhanced by the addition of Pq...
November 1, 2016: Journal of Plant Physiology
Claramaría Rodríguez-González, Pamela Velázquez-Villalba, Pedro Salas, Víctor M Castaño
A green facile method has been successfully used for the synthesis of graphene oxide sheets decorated with silver nanoparticles (rGO/AgNPs), employing graphite oxide as a precursor of graphene oxide (GO), AgNO3 as a precursor of Ag nanoparticles (AgNPs), and geranium (Pelargonium graveolens) extract as reducing agent. Synthesis was accomplished using the weight ratios 1:1 and 1:3 GO/Ag, respectively. The synthesised nanocomposites were characterised by scanning electron microscopy, transmission electron microscopy, atomic force microscopy, X-ray diffraction, UV-visible spectroscopy, Raman spectroscopy, energy dispersive X-ray spectroscopy and thermogravimetric analysis...
October 2016: IET Nanobiotechnology
Felix Grewe, Andan Zhu, Jeffrey P Mower
The mitochondrial nad1 gene of seed plants has a complex structure, including four introns in cis or trans configurations and a maturase gene (matR) hosted within the final intron. In the geranium family (Geraniaceae), however, sequencing of representative species revealed that three of the four introns, including one in a trans configuration and another that hosts matR, were lost from the nad1 gene in their common ancestor. Despite the loss of the host intron, matR has been retained as a freestanding gene in most genera of the family, indicating that this maturase has additional functions beyond the splicing of its host intron...
October 30, 2016: Genome Biology and Evolution
Jyoti Singh Jadaun, Neelam S Sangwan, Lokesh K Narnoliya, Neha Singh, Shilpi Bansal, Bhawana Mishra, Rajender Singh Sangwan
Rose-scented geranium (Pelargonium spp.) is one of the most important aromatic plants and is well known for its diverse perfumery uses. Its economic importance is due to presence of fragrance rich essential oil of its foliage. The essential oil is a mixture of various volatile phytochemicals which are mainly terpenes (isoprenoids) in nature. In this study, genes related to isoprenoid biosynthesis (DXS, DXR and HMGR) were isolated, cloned and confirmed by sequencing. Further, the first gene of 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, 1-deoxy-D-xylulose-5-phosphate synthase (DXS), was made full length by using rapid amplification of cDNA ends strategy...
August 31, 2016: Physiologia Plantarum
Janice Luehring Giongo, Rodrigo de Almeida Vaucher, Viviane Pedroso Fausto, Priscilla Maciel Quatrin, Leonardo Quintana Soares Lopes, Roberto Christ Vianna Santos, André Gündel, Patrícia Gomes, Martin Steppe
Infections due to microbial biofilm formation on the surface of catheters and other medical devices are constantly reported as a major cause of morbidity and mortality in patients admitted to hospitals. Furthermore, sessile cells are more resistant to phagocytosis and most antimicrobial, which complicates the treatment of such infections. Researches aimed at new antimicrobial originating mainly from plants have increased in recent years and the development of new strategies for their release is critical in combating the formation of biofilms...
November 2016: Microbial Pathogenesis
Stefanie Duchow, Renate I Dahlke, Thomas Geske, Wolfgang Blaschek, Birgit Classen
Root extracts of the medicinal plant Pelargonium sidoides, native to South Africa, are used globally for the treatment of common cold and cough. Due to an increasing economic commercialization of P. sidoides remedies, wild collections of root material should be accompanied by effective methods for plant propagation like somatic embryogenesis. Based on this, the influence of arabinogalactan-proteins (AGPs) on somatic embryogenesis and plant propagation of P. sidoides has been investigated. High-molecular weight AGPs have been isolated from dried roots as well as from cell cultures of P...
November 5, 2016: Carbohydrate Polymers
Nazlihan Aztopal, Buse Cevatemre, Mehmet Sarimahmut, Ferda Ari, Egemen Dere, Mustafa Zafer Ozel, Mehmet Firat, Engin Ulukaya
Pelargonium species have various uses in folk medicine as traditional remedies, and several of them have been screened for their biological activity, including anticancer. Pelargonium quercetorum Agnew (P. quercetorum) is traditionally used for its anthelminthic activity. However, little is known about its biological activity or its effect on cancer cells. The aim of the present study was to determine the cytotoxic activity of P. quercetorum extract on lung cancer cell lines with varying properties. Following the analyses of its chemical composition, the cytotoxic activity was screened by the adenosine triphosphate viability test...
August 2016: Oncology Letters
Anna K Koch, Petra Klose, Romy Lauche, Holger Cramer, Jennifer Baasch, Gustav J Dobos, Jost Langhorst
Herbal medicine is a promising alternative in the treatment of acute rhinosinusitis (ARS). We performed a systematic review for phytopharmaceutical treatments of ARS. A computerized search of databases (Cochrane Library, PubMed, and Scopus) up to 16 September 2015 was performed. Randomized controlled trials (RCTs) and controlled trials (CTs) were included and assessed using the Cochrane risk of bias tool. Seven trials on Pelargonium sidoides (EPs 7630, Umckaloabo®), Myrtol (GeloMyrtol® forte), BNO 1016 (Sinupret® extract), BNO 101 (Sinupret®), Cyclamen europaeum (Nasodren®), and Esberitox® were included...
2016: Forschende Komplementärmedizin, Research in Complementary Medicine
Georgia Tooulakou, Andreas Giannopoulos, Dimosthenis Nikolopoulos, Panagiota Bresta, Elissavet Dotsika, Malvina G Orkoula, Christos G Kontoyannis, Costas Fasseas, Georgios Liakopoulos, Maria I Klapa, George Karabourniotis
Calcium oxalate crystals are widespread among animals and plants. In land plants, crystals often reach high amounts, up to 80% of dry biomass. They are formed within specific cells, and their accumulation constitutes a normal activity rather than a pathological symptom, as occurs in animals. Despite their ubiquity, our knowledge on the formation and the possible role(s) of these crystals remains limited. We show that the mesophyll crystals of pigweed (Amaranthus hybridus) exhibit diurnal volume changes with a gradual decrease during daytime and a total recovery during the night...
August 2016: Plant Physiology
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