keyword
MENU ▼
Read by QxMD icon Read
search

IDA

keyword
https://www.readbyqxmd.com/read/29145441/distinct-t-and-nk-cell-populations-may-serve-as-immune-correlates-of-protection-against-symptomatic-pandemic-influenza-a-h1n1-virus-infection-during-pregnancy
#1
Miloje Savic, Jennifer L Dembinski, Ida Laake, Olav Hungnes, Rebecca Cox, Fredrik Oftung, Lill Trogstad, Siri Mjaaland
Maternal influenza infection during pregnancy is associated with increased risk of morbidity and mortality. However, the link between the anti-influenza immune responses and health-related risks during infection is not well understood. We have analyzed memory T and NK cell mediated immunity (CMI) responses in pandemic influenza A(H1N1)pdm09 (pdm09) virus infected non-vaccinated pregnant women participating in the Norwegian Influenza Pregnancy Cohort (NorFlu). The cohort includes information on immunization, self-reported health and disease status, and biological samples (plasma and PBMC)...
2017: PloS One
https://www.readbyqxmd.com/read/29143958/intraspinal-mesenchymal-chondrosarcoma-report-of-a-pediatric-case-and-literature-review
#2
Angela Di Giannatale, Marta Colletti, Ida Russo, Valentina Ferruzzi, Vito Andrea Dell' Anna, Raffaele Cozza, Giovanna Stefania Colafati, Raffaella Messina, Angela Mastronuzzi, Rita De Vito, Giuseppe Maria Milano
PURPOSE: Mesenchymal chondrosarcoma (MCS) is an aggressive variant of chondrosarcoma and is a rare tumor, particularly within the pediatric population. Commonly, MCS originates in the bone, but it can also arise in extraskeletal sites, such as the brain and the intraspinal area. Due to the rarity of this tumor, there are no guidelines for its optimal treatment. METHODS: We report a case of intradural extramedullary MCS, located at the T11-T12 level, in a 14-year-old male...
November 15, 2017: Tumori
https://www.readbyqxmd.com/read/29142521/fatal-infections-in-older-patients-with-inflammatory-bowel-disease-on-anti-tumor-necrosis-factor-therapy
#3
Way-Seah Lee, Najib Azmi, Ruey-Terng Ng, Sik-Yong Ong, Sasheela Sri La Ponnampalavanar, Sanjiv Mahadeva, Ida Hilmi
Anti-tumor necrosis factor (anti-TNF) is highly effective in inflammatory bowel disease (IBD); however, it is associated with an increased risk of infections, particularly in older adults. We reviewed 349 patients with IBD, who were observed over a 12-month period, 74 of whom had received anti-TNF therapy (71 patients were aged <60 years and 3 were aged ≥60 years). All the 3 older patients developed serious infectious complications after receiving anti-TNFs, although all of them were also on concomitant immunosuppressive therapy...
October 2017: Intestinal Research
https://www.readbyqxmd.com/read/29137191/maternal-iodine-intake-and-offspring-attention-deficit-hyperactivity-disorder-results-from-a-large-prospective-cohort-study
#4
Marianne Hope Abel, Eivind Ystrom, Ida Henriette Caspersen, Helle Margrete Meltzer, Heidi Aase, Liv Elin Torheim, Ragna Bugge Askeland, Ted Reichborn-Kjennerud, Anne Lise Brantsæter
Current knowledge about the relationship between mild to moderately inadequate maternal iodine intake and/or supplemental iodine on child neurodevelopment is sparse. Using information from 77,164 mother-child pairs in the Norwegian Mother and Child Cohort Study, this study explored associations between maternal iodine intake and child attention-deficit/hyperactivity disorder (ADHD) diagnosis, registered in the Norwegian Patient Registry and maternally-reported child ADHD symptoms at eight years of age. Pregnant women reported food and supplement intakes by questionnaire in gestational week 22...
November 13, 2017: Nutrients
https://www.readbyqxmd.com/read/29134656/long-term-dynamic-synaptic-reorganization-after-gabaergic-precursor-cell-transplantation-into-adult-mouse-spinal-cord
#5
Ida J Llewellyn-Smith, Allan I Basbaum, João M Bráz
Transplanting embryonic precursors of GABAergic neurons from the medial ganglionic eminence (MGE) into adult mouse spinal cord ameliorates mechanical and thermal hypersensitivity in peripheral nerve injury models of neuropathic pain. Although Fos and transneuronal tracing studies strongly suggest that integration of MGE-derived neurons into host spinal cord circuits underlies recovery of function, the extent to which there is synaptic integration of the transplanted cells has not been established. Here, we used electron microscopic immunocytochemistry to assess directly integration of GFP-expressing MGE-derived neuronal precursors into dorsal horn circuitry in intact, adult mice with short- (5-6 weeks) or long-term (4-6 months) transplants...
November 13, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29131949/crystalline-coordination-networks-of-zero-valent-metal-centers-formation-of-a-3-dimensional-ni-0-framework-with-m-terphenyl-diisocyanides
#6
Douglas W Agnew, Ida M DiMucci, Alejandra Arroyave, Milan Gembicky, Curtis E Moore, Samantha N MacMillan, Arnold L Rheingold, Kyle M Lancaster, Joshua S Figueroa
A permanently porous, three-dimensional metal-organic material formed from zero-valent metal nodes is presented. Combination of ditopic m-terphenyl diisocyanide, [CNArMes2]2, and the d10 Ni(0) precursor Ni(COD)2, produces a porous metal-organic material featuring tetrahedral [Ni(CNArMes2)4]n structural sites. X-ray absorption spectroscopy provides firm evidence for the presence of Ni(0) centers, while gas-sorption and differential-scanning calorimetry analysis reveal the characteristics of a robust network with a micro-domain N2-adsorption profile...
November 13, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29131157/targeting-the-t-cell-receptor-%C3%AE-chain-constant-region-for-immunotherapy-of-t-cell-malignancies
#7
Paul M Maciocia, Patrycja A Wawrzyniecka, Brian Philip, Ida Ricciardelli, Ayse U Akarca, Shimobi C Onuoha, Mateusz Legut, David K Cole, Andrew K Sewell, Giuseppe Gritti, Joan Somja, Miguel A Piris, Karl S Peggs, David C Linch, Teresa Marafioti, Martin A Pule
Mature T cell cancers are typically aggressive, treatment resistant and associated with poor prognosis. Clinical application of immunotherapeutic approaches has been limited by a lack of target antigens that discriminate malignant from healthy (normal) T cells. Unlike B cell depletion, pan-T cell aplasia is prohibitively toxic. We report a new targeting strategy based on the mutually exclusive expression of T cell receptor β-chain constant domains 1 and 2 (TRBC1 and TRBC2). We identify an antibody with unique TRBC1 specificity and use it to demonstrate that normal and virus-specific T cell populations contain both TRBC1(+) and TRBC2(+) compartments, whereas malignancies are restricted to only one...
November 13, 2017: Nature Medicine
https://www.readbyqxmd.com/read/29130114/workplace-bullying-and-violence-as-risk-factors-for-type-2-diabetes-a-multicohort-study-and-meta-analysis
#8
Tianwei Xu, Linda L Magnusson Hanson, Theis Lange, Liis Starkopf, Hugo Westerlund, Ida E H Madsen, Reiner Rugulies, Jaana Pentti, Sari Stenholm, Jussi Vahtera, Åse M Hansen, Mika Kivimäki, Naja H Rod
AIMS/HYPOTHESIS: The aim of this multicohort study was to examine whether employees exposed to social stressors at work, such as workplace bullying and violence, have an increased risk of type 2 diabetes. METHODS: The study included 45,905 men and women (40-65 years of age and free of diabetes at baseline) from four studies in Sweden, Denmark and Finland. Workplace bullying and violence were self-reported at baseline. Incident diabetes was ascertained through national health and medication records and death registers...
November 13, 2017: Diabetologia
https://www.readbyqxmd.com/read/29129569/the-triolein-aqueous-interface-and-lipase-activity-studied-by-spectroscopic-ellipsometry-and-coarse-grained-simulations
#9
Arne Stamm, Allan Svendsen, Jakob Skjold-Jørgensen, Thomas Vissing, Ida Berts, Tommy Nylander
In spite of the importance of the triglyceride aqueous interface for processes like emulsification, surfactant interactions and lipase activity, relatively little is known about this interface compared to that between alkanes and water. Here, the contact between triolein and water was investigated in terms of water inclusion in the oil phase and orientation of the molecules at the interface. Coarse grained models of triglycerides in contact with water were constructed and correlated with experimental results of the changes in thickness and refractive index, obtained using spectroscopic ellipsometry of spin-coated triolein films...
November 9, 2017: Chemistry and Physics of Lipids
https://www.readbyqxmd.com/read/29129158/practical-gastrointestinal-investigation-of-iron-deficiency-anaemia
#10
Anjan K Banerjee, Valerio Celentano, Jim Khan, Gaius Longcroft-Wheaton, Amanda Quine, Pradeep Bhandari
About 10% of oesophagogastroduodenoscopies (OGDs) and colonoscopies are done for investigation of iron deficiency anemia (IDA) . Much of the existing guidance on investigation of IDA predates CRC screening, which has driven significant improvements in colonoscopy quality and completion rates, as well as a reduction in Helicobacter pylori prevalence and increase in PPI usage, and therefore probably needs re-consideration. New investigations, e.g. CT colonography, enteroscopy and capsule endoscopy have also been introduced...
November 13, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29125435/health-literacy-among-medically-underserved-the-role-of-demographic-factors-social-influence-and-religious-beliefs
#11
Shannon M Christy, Clement K Gwede, Steven K Sutton, Enmanuel Chavarria, Stacy N Davis, Rania Abdulla, Chitra Ravindra, Ida Schultz, Richard Roetzheim, Cathy D Meade
The current study examined the sociodemographic and psychosocial variables that predicted being at risk for low health literacy among a population of racially and ethnically diverse patients accessing primary care services at community-based clinics. Participants (N = 416) were aged 50-75 years, currently not up-to-date with colorectal cancer (CRC) screening, at average CRC risk, and enrolled in a randomized controlled trial (RCT) aimed at promoting CRC screening. Participants completed a baseline interview that assessed health literacy as measured by Rapid Estimate of Adult Literacy in Medicine-Revised, sociodemographic factors, and psychosocial variables (e...
November 10, 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/29121915/clinical-monitoring-of-cardiac-output-assessed-by-transoesophageal-echocardiography-in-anaesthetised-dogs-a-comparison-with-the-thermodilution-technique
#12
Matheus M Mantovani, Denise T Fantoni, André M Gimenes, Jacqueline R de Castro, Patrícia B Flor, Keila K Ida, Denise S Schwartz
BACKGROUND: Cardiac output (CO) is an important haemodynamic parameter to monitor in patients during surgery. However, the majority of the techniques for measuring CO have a limited application in veterinary practice due to their invasive approach and associated complexity and risks. Transoesophageal echocardiography (TEE) is a technique used to monitor cardiac function in human patients during surgical procedures and allows CO to be measured non-invasively. This prospective clinical study aimed to compare the transoesophageal echocardiography using a transgastric view of the left ventricular outflow tract (LVOT) and the thermodilution (TD) technique for the assessment of CO during mean arterial pressure of 65-80 mmHg (normotension) and <65 mmHg (hypotension) in dogs undergoing elective surgery...
November 9, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29121448/malaria-exacerbates-inflammation-associated-elevation-in-ferritin-and-soluble-transferrin-receptor-with-only-modest-effects-on-iron-deficiency-and-iron-deficiency-anemia-among-rural-zambian-children
#13
Maxwell A Barffour, Kerry J Schulze, Christian L Coles, Justin Chileshe, Ng'andwe Kalungwana, Ward Siamusantu, Margia Arguello, William J Moss, Keith P West, Amanda C Palmer
OBJECTIVE: In 4-8-year-old Zambian children (n=744), we evaluated the effects of adjusting for inflammation (α1-acid glycoprotein > 1 g/L), with or without additional adjustment for malaria, on prevalence estimates of iron deficiency (ID) and iron deficiency anemia (IDA) during low malaria (LowM) and high malaria (HighM) transmission seasons. METHODS: To estimate adjustment factors, children were classified as: a) reference (malaria negative without inflammation), b) inflammation without malaria (I), c) malaria without inflammation (M), and d) inflammation with malaria (IM)...
November 9, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29120150/incidence-etiology-and-outcome-of-ventilator-associated-pneumonia-in-patients-with-percutaneous-tracheotomy
#14
Tihana Magdić Turković, Melanija Obraz, Milana Zlatić Glogoški, Ida Juranić, Bruna Bodulica, Josipa Kovačić
Although the incidence of ventilator-associated pneumonia (VAP) is very high, there are still many uncertainties about clinical course of VAP among tracheotomized patients. The goal of the present study was to determine the impact of tracheotomy on VAP incidence and etiology, as well as outcome of VAP patients with tracheotomy. The study was conducted in a 15-bed Surgical and Neurosurgical Intensive Care Unit (ICU), Sestre milosrdnice University Hospital Center in Zagreb, Croatia. The study included all patients undergoing only percutaneous tracheotomy during the study period...
March 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29119304/is-thrombocytosis-always-an-indicator-of-autosplenectomy-in-patients-with-systemic-lupus-erythematosus
#15
Döndü Üsküdar Cansu, Hava Üsküdar Teke, Ahmet Musmul, Cengiz Korkmaz
In systemic lupus erythematosus (SLE), the most commonly encountered finding related to platelets is thrombocytopenia whereas thrombocytosis is rarely reported. Our aim here was to reveal the type and the frequency of thrombocytosis in SLE patients along with its causes. Data of patients were evaluated retrospectively. Patients who had a platelet count of > 450,000/mm(3) (> 450 × 10(9)/L) in at least two subsequent counts and lasting more than 6 months during the follow-up were considered to have "persistent thrombocytosis"...
November 8, 2017: Rheumatology International
https://www.readbyqxmd.com/read/29118465/antioxidant-and-anti-inflammatory-activities-in-extracts-from-minke-whale-balaenoptera-acutorostrata-blubber
#16
Mari Johannessen Walquist, Svein Kristian Stormo, Ida-Johanne Jensen, Bjarne Østerud, Karl-Erik Eilertsen
Intake of long-chain omega-3 polyunsaturated fatty acids (LC-n3-PUFA) is commonly recognized to reduce cardiovascular disease (CVD). In previous studies, cold-pressed whale oil (CWO) and cod liver oil (CLO) were given as a dietary supplement to healthy volunteers. Even though CWO contains less than half the amount of LC-n3-PUFA of CLO, CWO supplement resulted in beneficial effects on anti-inflammatory and CVD risk markers compared to CLO. In the present study, we prepared virtually lipid-free extracts from CWO and CLO and evaluated the antioxidative capacity (AOC) and anti-inflammatory effects...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/29116651/probing-the-effect-of-polymer-molecular-weight-on-penetration-into-the-wood-cell-wall-using-polyethylenimine-pei-as-a-model-compound
#17
Brian Dorvel, Praveenkumar Boopalachandran, Ida Chen, Andrew Bowling, Kerry Williams, Steve King
Decking is one of the largest applications for the treated wood market. The most challenging property to obtain for treated wood is dimensional stability, which can be achieved, in part, by cell wall bulking, cell wall polymer crosslinking and removal of hygroscopic components in the cell wall. A commonly accepted key requirement is for the actives to infuse through the cell wall, which has a microporosity of ∼5-13 nm. Equally as challenging is being able to measure and quantify the cell wall penetration...
November 8, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/29116170/injection-of-high-dose-botulinum-toxin-a-leads-to-impaired-skeletal-muscle-function-and-damage-of-the-fibrilar-and-non-fibrilar-structures
#18
Jessica Pingel, Mikkel Schou Nielsen, Torsten Lauridsen, Kristian Rix, Martin Bech, Tine Alkjaer, Ida Torp Andersen, Jens Bo Nielsen, R Feidenhansl
Botulinum-toxin A (BoNT/A) is used for a wide range of conditions. Intramuscular administration of BoNT/A inhibits the release of acetylcholine at the neuromuscular junction from presynaptic motor neurons causing muscle-paralysis. The aim of the present study was to investigate the effect of high dose intramuscular BoNT/A injections (6 UI = 60 pg) on muscle tissue. The gait pattern of the rats was significantly affected 3 weeks after BoNT/A injection. The ankle joint rotated externally, the rats became flat footed, and the stride length decreased after BoNT/A injection...
November 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29116125/erratum-large-meta-analysis-of-genome-wide-association-studies-identifies-five-loci-for-lean-body-mass
#19
M Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M Yerges-Armstrong, Wen-Chi Chou, Lisette Stolk, Gregory Livshits, Linda Broer, Toby Johnson, Daniel L Koller, Zoltán Kutalik, Jian'an Luan, Ida Malkin, Janina S Ried, Albert V Smith, Gudmar Thorleifsson, Liesbeth Vandenput, Jing Hua Zhao, Weihua Zhang, Ali Aghdassi, Kristina Åkesson, Najaf Amin, Leslie J Baier, Inês Barroso, David A Bennett, Lars Bertram, Rainer Biffar, Murielle Bochud, Michael Boehnke, Ingrid B Borecki, Aron S Buchman, Liisa Byberg, Harry Campbell, Natalia Campos Obanda, Jane A Cauley, Peggy M Cawthon, Henna Cederberg, Zhao Chen, Nam H Cho, Hyung Jin Choi, Melina Claussnitzer, Francis Collins, Steven R Cummings, Philip L De Jager, Ilja Demuth, Rosalie A M Dhonukshe-Rutten, Luda Diatchenko, Gudny Eiriksdottir, Anke W Enneman, Mike Erdos, Johan G Eriksson, Joel Eriksson, Karol Estrada, Daniel S Evans, Mary F Feitosa, Mao Fu, Melissa Garcia, Christian Gieger, Thomas Girke, Nicole L Glazer, Harald Grallert, Jagvir Grewal, Bok-Ghee Han, Robert L Hanson, Caroline Hayward, Albert Hofman, Eric P Hoffman, Georg Homuth, Wen-Chi Hsueh, Monica J Hubal, Alan Hubbard, Kim M Huffman, Lise B Husted, Thomas Illig, Erik Ingelsson, Till Ittermann, John-Olov Jansson, Joanne M Jordan, Antti Jula, Magnus Karlsson, Kay-Tee Khaw, Tuomas O Kilpeläinen, Norman Klopp, Jacqueline S L Kloth, Heikki A Koistinen, William E Kraus, Stephen Kritchevsky, Teemu Kuulasmaa, Johanna Kuusisto, Markku Laakso, Jari Lahti, Thomas Lang, Bente L Langdahl, Lenore J Launer, Jong-Young Lee, Markus M Lerch, Joshua R Lewis, Lars Lind, Cecilia Lindgren, Yongmei Liu, Tian Liu, Youfang Liu, Östen Ljunggren, Mattias Lorentzon, Robert N Luben, William Maixner, Fiona E McGuigan, Carolina Medina-Gomez, Thomas Meitinger, Håkan Melhus, Dan Mellström, Simon Melov, Karl Michaëlsson, Braxton D Mitchell, Andrew P Morris, Leif Mosekilde, Anne Newman, Carrie M Nielson, Jeffrey R O'Connell, Ben A Oostra, Eric S Orwoll, Aarno Palotie, Stephen C J Parker, Munro Peacock, Markus Perola, Annette Peters, Ozren Polasek, Richard L Prince, Katri Räikkönen, Stuart H Ralston, Samuli Ripatti, John A Robbins, Jerome I Rotter, Igor Rudan, Veikko Salomaa, Suzanne Satterfield, Eric E Schadt, Sabine Schipf, Laura Scott, Joban Sehmi, Jian Shen, Chan Soo Shin, Gunnar Sigurdsson, Shad Smith, Nicole Soranzo, Alena Stančáková, Elisabeth Steinhagen-Thiessen, Elizabeth A Streeten, Unnur Styrkarsdottir, Karin M A Swart, Sian-Tsung Tan, Mark A Tarnopolsky, Patricia Thompson, Cynthia A Thomson, Unnur Thorsteinsdottir, Emmi Tikkanen, Gregory J Tranah, Jaakko Tuomilehto, Natasja M van Schoor, Arjun Verma, Peter Vollenweider, Henry Völzke, Jean Wactawski-Wende, Mark Walker, Michael N Weedon, Ryan Welch, H-Erich Wichmann, Elisabeth Widen, Frances M K Williams, James F Wilson, Nicole C Wright, Weijia Xie, Lei Yu, Yanhua Zhou, John C Chambers, Angela Döring, Cornelia M van Duijn, Michael J Econs, Vilmundur Gudnason, Jaspal S Kooner, Bruce M Psaty, Timothy D Spector, Kari Stefansson, Fernando Rivadeneira, André G Uitterlinden, Nicholas J Wareham, Vicky Ossowski, Dawn Waterworth, Ruth J F Loos, David Karasik, Tamara B Harris, Claes Ohlsson, Douglas P Kiel
A correction to this article has been published and is linked from the HTML version of this article.
November 7, 2017: Nature Communications
https://www.readbyqxmd.com/read/29113992/axonemal-dynein-assembly-requires-the-r2tp-complex-component-pontin
#20
Yuanyuan Li, Lu Zhao, Shiaulou Yuan, Jiefang Zhang, Zhaoxia Sun
Pontin (Ruvbl1) and Reptin (Ruvbl2) are closely related AAA ATPases. They are components of the Ruvbl1-Rvubl2-Tah1-Pih1 (R2TP) complexes that function as co-chaperones for the assembly of multiple macromolecular protein complexes. Here, we show that Pontin is essential for cilia motility in both zebrafish and mouse and that Pontin and Reptin function cooperatively in this process. pontin zebrafish mutants display phenotypes tightly associated with cilia defects and cilia motility is lost in a number of ciliated tissues along with a reduction in the number of both outer and inner dynein arms (ODAs and IDAs)...
November 7, 2017: Development
keyword
keyword
53021
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"