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https://www.readbyqxmd.com/read/29232627/the-phenomenology-of-cell-size-control
#1
REVIEW
Kurt M Schmoller
Cells control their size through an intricate balance of cell growth, cell division, and cell death. Extensive work on unicellular model organisms revealed that cell-size-dependent cell cycle progression accounts for major aspects of cell size regulation and provided insights into the underlying molecular mechanisms. Nevertheless, elaborate live-cell imaging approaches still reveal new phenomenological observations that challenge our simplified models of size regulation and raise the question of what determines optimal cell size...
December 9, 2017: Current Opinion in Cell Biology
https://www.readbyqxmd.com/read/29232595/a-unified-computational-account-of-cumulative-semantic-semantic-blocking-and-semantic-distractor-effects-in-picture-naming
#2
Ardi Roelofs
Computational models of lexical selection in spoken word production have been applied to semantic interference effects in picture naming response times obtained with continuous naming, blocked-cyclic naming, and picture-word interference paradigms. However, a unified computational account of the effects in the three paradigms is lacking. Here, I show that the inclusion of conceptual bias in the WEAVER++ model (Levelt, Roelofs, & Meyer, 1999) explains cumulative semantic and semantic blocking effects while preserving the model's account of semantic distractor effects...
December 9, 2017: Cognition
https://www.readbyqxmd.com/read/29232259/the-experience-of-head-and-neck-cancer-survivorship-including-laryngectomy-an-integrated-biopsychosocial-model
#3
Marlene C Jacobson
PURPOSE OF REVIEW: The head and neck cancer (HNC) survivorship experience is unique among cancer populations. This review seeks to explore the HNC survivor experience associated with altered upper aerodigestive tract (UADT) function using principles of survivorship. RECENT FINDINGS: HNC survivors experience complex physical, functional, and psychosocial challenges related to UADT dysfunction. Interventions need to address all of these dimensions being mindful of the survivor experience...
December 9, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29230152/development-of-a-mixed-methods-investigation-of-process-and-outcomes-of-community-based-participatory-research
#4
Julie Lucero, Nina Wallerstein, Bonnie Duran, Margarita Alegria, Ella Greene-Moton, Barbara Israel, Sarah Kastelic, Maya Magarati, John Oetzel, Cynthia Pearson, Amy Schulz, Malia Villegas, Emily R White Hat
This article describes a mixed methods study of community-based participatory research (CBPR) partnership practices and the links between these practices and changes in health status and disparities outcomes. Directed by a CBPR conceptual model and grounded in indigenous-transformative theory, our nation-wide, cross-site study showcases the value of a mixed methods approach for better understanding the complexity of CBPR partnerships across diverse community and research contexts. The article then provides examples of how an iterative, integrated approach to our mixed methods analysis yielded enriched understandings of two key constructs of the model: trust and governance...
January 2018: Journal of Mixed Methods Research
https://www.readbyqxmd.com/read/29228986/addressing-vulnerability-building-resilience-community-based-adaptation-to-vector-borne-diseases-in-the-context-of-global-change
#5
REVIEW
Kevin Louis Bardosh, Sadie Ryan, Kris Ebi, Susan Welburn, Burton Singer
BACKGROUND: The threat of a rapidly changing planet - of coupled social, environmental and climatic change - pose new conceptual and practical challenges in responding to vector-borne diseases. These include non-linear and uncertain spatial-temporal change dynamics associated with climate, animals, land, water, food, settlement, conflict, ecology and human socio-cultural, economic and political-institutional systems. To date, research efforts have been dominated by disease modeling, which has provided limited practical advice to policymakers and practitioners in developing policies and programmes on the ground...
December 11, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29228977/a-systematic-review-of-the-application-of-wilson-and-cleary-health-related-quality-of-life-model-in-chronic-diseases
#6
REVIEW
Adedokun Oluwafemi Ojelabi, Yitka Graham, Catherine Haighton, Jonathan Ling
BACKGROUND: A conceptual model approach to clarify the elements of health-related quality of life (HRQL), their determinants and causal pathways is needed to aid researchers, health practitioners and policy makers in their bid to improve HRQL outcomes in patients. The aim of this systematic review was to appraise empirical evidence on the performance of the Wilson and Cleary Model of HRQL. METHODS: We conducted a search of MEDLINE, Science Direct, PsyARTICLES and CINAHL databases to identify articles that used Wilson and Cleary model to examine HRQL in chronic diseases...
December 11, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29228932/narratives-of-community-engagement-a-systematic-review-derived-conceptual-framework-for-public-health-interventions
#7
Ginny Brunton, James Thomas, Alison O'Mara-Eves, Farah Jamal, Sandy Oliver, Josephine Kavanagh
BACKGROUND: Government policy increasingly supports engaging communities to promote health. It is critical to consider whether such strategies are effective, for whom, and under what circumstances. However, 'community engagement' is defined in diverse ways and employed for different reasons. Considering the theory and context we developed a conceptual framework which informs understanding about what makes an effective (or ineffective) community engagement intervention. METHODS: We conducted a systematic review of community engagement in public health interventions using: stakeholder involvement; searching, screening, appraisal and coding of research literature; and iterative thematic syntheses and meta-analysis...
December 11, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29228393/quantifying-the-arousal-threshold-using-polysomnography-in-obstructive-sleep-apnea
#8
Scott A Sands, Philip I Terrill, Bradley A Edwards, Luigi Taranto Montemurro, Ali Azarbarzin, Melania Marques, Camila M de Melo, Stephen H Loring, James P Butler, David White, Andrew Wellman
Objectives: Precision medicine for obstructive sleep apnea (OSA) requires non-invasive estimates of each patient's pathophysiological "traits". Here we provide the first, automated technique to quantify the respiratory arousal threshold-defined as the level of ventilatory drive triggering arousal from sleep-using diagnostic polysomnographic signals in patients with OSA. Methods: Ventilatory drive preceding clinically-scored arousals was estimated from polysomnographic studies by fitting a respiratory control model (Terrill P et al...
November 9, 2017: Sleep
https://www.readbyqxmd.com/read/29227834/personality-pathology-grows-up-adolescence-as-a-sensitive-period
#9
REVIEW
Carla Sharp, Kiana Wall
There is mounting evidence that personality pathology, in particular, borderline pathology is a valid and reliable construct in adolescence, with prevalence, phenomenology, stability and risk factors similar to that of adult borderline personality disorder. Scientific evidence also delineates a marked separation of course and outcome of adolescent borderline personality disorder from other disorders and supports the efficacy of disorder-specific treatment. The current article addresses recent findings in these areas which point to adolescence as a sensitive period for the development for personality pathology...
December 6, 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/29227432/cpd-and-kt-models-used-and-opportunities-for-synergy
#10
Joan Sargeant, Francine Borduas, Anne Sales, Doug Klein, Brenna Lynn, Heather Stenerson
The two fields of continuing professional development (CPD) and knowledge translation (KT) within the health care sector, and their related research have developed as somewhat parallel paths with limited points of overlap or intersection. This is slowly beginning to change. The purpose of this paper is to describe and compare the dominant conceptual models informing each field with the view of increasing understanding and appreciation of the two fields, how they are similar and where they differ, and the current and potential points of intersection...
October 2017: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/29225424/parametric-analysis-of-electromechanical-and-fatigue-performance-of-total-knee-replacement-bearing-with-embedded-piezoelectric-transducers
#11
Mohsen Safaei, R Michael Meneghini, Steven R Anton
Total knee arthroplasty (TKA) is a common procedure in the United States; it has been estimated that about 4 million people are currently living with primary knee replacement in this country. Despite huge improvements in material properties, implant design, and surgical techniques, some implants fail a few years after surgery. A lack of information about in vivo kinetics of the knee prevents the establishment of a correlated intra- and postoperative loading pattern in knee implants. In this study, a conceptual design of an ultra high molecular weight (UHMW) knee bearing with embedded piezoelectric transducers is proposed, which is able to measure the reaction forces from knee motion as well as harvest energy to power embedded electronics...
September 2017: Smart Materials & Structures
https://www.readbyqxmd.com/read/29223197/an-estimation-of-a-nonlinear-dynamic-process-using-latent-class-extended-mixed-models-affect-profiles-after-terrorist-attacks
#12
Roberto Burro, Daniela Raccanello, Margherita Pasini, Margherita Brondino
Conceptualizing affect as a complex nonlinear dynamic process, we used latent class extended mixed models (LCMM) to understand whether there were unobserved groupings in a dataset including longitudinal measures. Our aim was to identify affect profiles over time in people vicariously exposed to terrorism, studying their relations with personality traits. The participants were 193 university students who completed online measures of affect during the seven days following two terrorist attacks (Paris, November 13, 2015; Brussels, March 22, 2016); Big Five personality traits; and antecedents of affect...
January 2018: Nonlinear Dynamics, Psychology, and Life Sciences
https://www.readbyqxmd.com/read/29221526/children-s-environmental-health-indicators-for-low-and-middle-income-countries-in-asia
#13
Eun Mi Jung, Eun Mee Kim, Minah Kang, Fiona Goldizen, Fiona Gore, Marie Noel Brune Drisse, Eun Hee Ha
BACKGROUND: Given that low- and middle-income countries (LMICs) in Asia still have high child mortality rates, improved monitoring using children's environmental health indicators (CEHI) may help reduce preventable deaths by creating healthy environments. OBJECTIVES: Thus, the aim of this study is to build a set of targeted CEHI that can be applied in LMICs in Asia through the CEHI initiative using a common conceptual framework. METHODS: A systematic review was conducted to identify the most frequently used framework for developing CEHI...
May 2017: Annals of Global Health
https://www.readbyqxmd.com/read/29219099/scoping-the-proximal-and-distal-dimensions-of-climate-change-on-health-and-wellbeing
#14
REVIEW
George Paterson Morris, Stefan Reis, Sheila Anne Beck, Lora Elderkin Fleming, William Neil Adger, Timothy Guy Benton, Michael Harold Depledge
The impacts of climate on health and wellbeing occur in time and space and through a range of indirect, complicated mechanisms. This diversity of pathways has major implications for national public health planning and influence on interventions that might help to mitigate and adapt to rapidly changing environmental conditions, nationally and internationally. This paper draws upon evidence from public health and adverse impact studies across climate science, hydrology, agriculture, public health, and the social sciences...
December 5, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29218819/a-conceptual-model-of-the-risk-of-elder-abuse-posed-by-incontinence-and-care-dependence
#15
Joan Ostaszkiewicz
AIMS AND OBJECTIVES: To describe and critically analyse the thinking that led to the concept of an association between incontinence, care dependence and elder abuse. BACKGROUND: Coercive or abusive continence care practices include chastising a person for their incontinence and overriding their attempts to resist continence care. Neglect in continence care is characterised by withholding or delaying responding to requests for help to maintain continence or to manage incontinence, and restricting a person's access to toileting assistance, incontinence aids or hygiene care...
December 8, 2017: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/29217695/harmonizing-methods-for-estimating-the-impact-of-contraceptive-use-on-unintended-pregnancy-abortion-and-maternal-health
#16
Ian Askew, Michelle Weinberger, Aisha Dasgupta, Jacqueline Darroch, Ellen Smith, John Stover, Melanie Yahner
Estimates of the potential impacts of contraceptive use on averting unintended pregnancies, total and unsafe abortions, maternal deaths, and newborn, infant, and child deaths provide evidence of the value of investments in family planning programs and thus are critically important for policy makers, donors, and advocates alike. Several research teams have independently developed mathematical models that estimate the number of adverse health outcomes averted due to contraceptive use. However, each modeling approach was designed for different purposes, and as such the methodological assumptions, data inputs, and mathematical algorithms initially used in each model differed; consequently, the models did not produce comparable estimates for the same outcome indicators...
December 7, 2017: Global Health, Science and Practice
https://www.readbyqxmd.com/read/29217169/enabling-new-graduate-midwives-to-work-in-midwifery-continuity-of-care-models-a-conceptual-model-for-implementation
#17
Allison M Cummins, Christine Catling, Caroline S E Homer
BACKGROUND: High-level evidence demonstrates midwifery continuity of care is beneficial for women and babies. Women have limited access to midwifery continuity of care models in Australia. One of the factors limiting women's access is recruiting enough midwives to work in continuity. Our research found that newly graduated midwives felt well prepared to work in midwifery led continuity of care models, were well supported to work in the models and the main driver to employing them was a need to staff the models...
December 4, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29216602/nursing-students-learning-the-pharmacology-of-diabetes-mellitus-with-complexity-based-computerized-models-a-quasi-experimental-study
#18
Ilana Dubovi, Efrat Dagan, Ola Sader Mazbar, Laila Nassar, Sharona T Levy
BACKGROUND: Pharmacology is a crucial component of medications administration in nursing, yet nursing students generally find it difficult and self-rate their pharmacology skills as low. OBJECTIVES: To evaluate nursing students learning pharmacology with the Pharmacology Inter-Leaved Learning-Cells environment, a novel approach to modeling biochemical interactions using a multiscale, computer-based model with a complexity perspective based on a small set of entities and simple rules...
November 23, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/29215328/a-realist-evaluation-of-social-prescribing-an-exploration-into-the-context-and-mechanisms-underpinning-a-pathway-linking-primary-care-with-the-voluntary-sector
#19
Marcello Bertotti, Caroline Frostick, Patrick Hutt, Ratna Sohanpal, Dawn Carnes
This article adopts a realist approach to evaluate a social prescribing pilot in the areas of Hackney and City in London (United Kingdom). It unpacks the contextual factors and mechanisms that influenced the development of this pilot for the benefits of GPs, commissioners and practitioners, and reflects on the realist approach to evaluation as a tool for the evaluation of health interventions. Primary care faces considerable challenges including the increase in long-term conditions, GP consultation rates, and widening health inequalities...
December 7, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29215192/forest-conversion-induces-seasonal-variation-in-microbial-%C3%AE-diversity
#20
Shengen Liu, Hang Wang, Ye Deng, Peng Tian, Qingkui Wang
World-wide conversion of natural forests to other land uses has profound effects on soil microbial communities. However, how soil microbial β-diversity responds to land-use change and its driving mechanisms remains poorly understood. In this study, therefore, we examined the effect of forest conversion from native broad-leaved forest to coniferous plantation on soil microbial β-diversity and its underlying mechanisms in both summer and winter in subtropical China. Microbial communities increasingly differed in structure as geographical distance between them increased, and the slope of the relationship among distances and community similarity differed among forest covers...
December 7, 2017: Environmental Microbiology
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