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https://www.readbyqxmd.com/read/28231131/effects-of-matrix-composition-on-detection-threshold-estimates-for-methyl-anthranilate-and-2-aminoacetophenone
#1
Demetra M Perry, John E Hayes
Conceptually, a detection threshold represents the lowest concentration at which an individual or a group of individuals can reliably perceive a given stimulus, with a commonly used operational definition of 50% performance above chance. Estimated detection thresholds (DTs), however, are often reported in the literature with little attention given to the matrix in which the stimuli were evaluated. Here, we highlight the influence of matrix effects on DTs for two odor-active compounds commonly found in Vitis Labrusca wines...
May 17, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28230575/patients-and-care-partners-perspectives-on-dignity-and-respect-during-acute-care-hospitalization
#2
Priscilla K Gazarian, Constance R C Morrison, Lisa Soleymani Lehmann, Orly Tamir, David W Bates, Ronen Rozenblum
BACKGROUND: Delivering patient-centered care (PCC) is essential to our healthcare system. Patient dignity and respect are foundational elements of PCC. Understanding patients' and their care partner's perspectives on the meaning of dignity and respect within a clinical care environment is critical to achieving our goal of PCC. OBJECTIVE: The aim of the study was to understand how patients and their care partners define, describe, and experience dignity and respect during hospitalization...
February 22, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28230413/the-effects-of-cognitive-behavioral-therapy-are-not-systematically-falling-a-revision-of-johnsen-and-friborg-2015
#3
Ioana A Cristea, Simona Stefan, Eirini Karyotaki, Daniel David, Steven D Hollon, Pim Cuijpers
In a meta-analysis, Johnsen and Friborg (2015) reported a significant negative relationship between publication year and the effect sizes (ESs) of cognitive-behavioral therapy (CBT) for depressive disorders, suggesting its effectiveness was falling. We identified a series of methodological and conceptual caveats and consequently redid the meta-analysis. We used the same inclusion criteria, but only included randomized controlled trials and searched for additional eligible trials. We computed both within-group and between-group ESs for the CBT arm for the Beck Depression Inventory (BDI) and the Hamilton Rating Scale for Depression (HRSD)...
March 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28229458/life-course-health-development-of-individuals-with-neurodevelopmental-conditions
#4
REVIEW
Robert J Palisano, Briano Di Rezze, Debra Stewart, Peter L Rosenbaum, Oksana Hlyva, Matthew Freeman, Tram Nguyen, Jan Willem Gorter
The life course health development (LCHD) model by Halfon et al. conceptualizes health development occurring through person-environment transactions that enable well-being and participation in desired social roles throughout life, areas that have not received adequate attention in healthcare. The aim of this 'perspectives' paper is to apply the six core tenets of the LCHD model and the concept of health development trajectories to individuals with lifelong neurodevelopmental conditions. We share the perspective that modifiable aspects of the environment often restrict health development; we then advocate that children, beginning at a young age, should engage in 'real-world' experiences that prepare them for current and future social roles...
February 23, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28229329/predicting-parent-health-related-quality-of-life-evaluating-conceptual-models
#5
Ellen K Defenderfer, Tiffany M Rybak, W Hobart Davies, Kristoffer S Berlin
PURPOSE: Parents of children with chronic illnesses are at risk for poor health-related quality of life (HRQoL), with numerous identified risk factors, but the most informative statistical model considering their combined impact is unclear. The authors conceptualized risk for poor HRQoL using a summed model, comprehensive multivariate model, and latent profile analysis (LPA). METHODS: Community parents completed an online survey, providing information about demographics, child's chronic illness, family functioning, and parent and child HRQoL...
February 22, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28228538/route-choice-in-pedestrians-determinants-for-initial-choices-and-revising-decisions
#6
Weichen Liao, Armel U Kemloh Wagoum, Nikolai W F Bode
In moving pedestrian crowds, the distribution of individuals over different available routes emerges from the decisions of individuals that may be influenced by the actions of others. Understanding this phenomenon not only is important for research into collective behaviour, but also has practical applications for building safety and event management. Here, we study the mechanisms underlying pedestrian route choice, focusing on how time-independent information, such as path lengths, and time-dependent information, such as queue lengths, affect both initial decisions and subsequent changes in route choices...
February 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28228512/what-do-territory-owners-defend-against
#7
REVIEW
Martin Hinsch, Jan Komdeur
Theoretical research on evolutionary aspects of territoriality has a long history. Existing studies, however, differ widely in modelling approach and research question. A generalized view on the evolution of territoriality is accordingly still missing. In this review, we show that territorial conflicts can be classified into qualitatively distinct types according to what mode of access to a territory which competitor attempts to gain. We argue that many of the inconsistencies between existing studies can be traced back to the fact that, while using the same terminology, different instances of these types of conflicts have been investigated...
February 22, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28226879/toward-a-low-cost-gait-analysis-system-for-clinical-and-free-living-assessment
#8
Cassim Ladha, Silvia Del Din, Kianoush Nazarpour, Aodhan Hickey, Rosie Morris, Michael Catt, Lynn Rochester, Alan Godfrey, Cassim Ladha, Silvia Del Din, Kianoush Nazarpour, Aodhan Hickey, Rosie Morris, Michael Catt, Lynn Rochester, Alan Godfrey, Rosie Morris, Cassim Ladha, Lynn Rochester, Alan Godfrey, Aodhan Hickey, Silvia Del Din, Kianoush Nazarpour, Michael Catt
Gait is an important clinical assessment tool since changes in gait may reflect changes in general health. Measurement of gait is a complex process which has been restricted to bespoke clinical facilities until recently. The use of inexpensive wearable technologies is an attractive alternative and offers the potential to assess gait in any environment. In this paper we present the development of a low cost analysis gait system built using entirely open source components. The system is used to capture spatio-temporal gait characteristics derived from an existing conceptual model, sensitive to ageing and neurodegenerative pathology (e...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226584/leveraging-imu-data-for-accurate-exercise-performance-classification-and-musculoskeletal-injury-risk-screening
#9
Darragh Whelan, Martin O'Reilly, Bingquan Huang, Oonagh Giggins, Tahar Kechadi, Brian Caulfield, Darragh Whelan, Martin O'Reilly, Bingquan Huang, Oonagh Giggins, Tahar Kechadi, Brian Caulfield, Martin O'Reilly, Brian Caulfield, Oonagh Giggins, Tahar Kechadi, Darragh Whelan, Bingquan Huang
Inertial measurement units (IMUs) are becoming increasingly prevalent as a method for low cost and portable biomechanical analysis. However, to date they have not been accepted into routine clinical practice. This is often due to a disconnect between translating the data collected by the sensors into meaningful and actionable information for end users. This paper outlines the work completed by our group in attempting to achieve this. We discuss the conceptual framework involved in our work, the methodological approach taken in analysing sensor signals and discuss possible application models...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226406/what-do-we-know-about-older-former-carers-key-issues-and-themes
#10
Mary Larkin, Alisoun Milne
Despite a significant growth in the number older former family carers, they remain largely invisible in carer-related research and literature. To begin to address this deficit, a four-stage literature review was conducted to identify existing knowledge about older former carers. Narrative synthesis of the findings yielded five themes - the concept of 'older former carer', the legacies of caring, influences on the legacies of caring, conceptualising post-caring and support services for older former carers. Critical analysis of these findings suggests that existing evidence has a number of strengths...
February 22, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28226302/towards-a-theoretical-model-on-medicines-as-a-health-need
#11
Claudia Marcela Vargas-Peláez, Luciano Soares, Marina Raijche Mattozo Rover, Carine Raquel Blatt, Aukje Mantel-Teeuwisse, Francisco Augusto Rossi Buenaventura, Luis Guillermo Restrepo, María Cristina Latorre, José Julián López, María Teresa Bürgin, Consuelo Silva, Silvana Nair Leite, Farias Mareni Rocha
Medicines are considered one of the main tools of western medicine to resolve health problems. Currently, medicines represent an important share of the countries' healthcare budget. In the Latin America region, access to essential medicines is still a challenge, although countries have established some measures in the last years in order to guarantee equitable access to medicines. A theoretical model is proposed for analysing the social, political, and economic factors that modulate the role of medicines as a health need and their influence on the accessibility and access to medicines...
February 15, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28226190/predictors-of-readiness-for-hospital-discharge-after-birth-building-evidence-for-practice
#12
Gabriella Malagon-Maldonado, Cynthia D Connelly, Ruth A Bush
BACKGROUND: Preparation for hospital discharge after birth became a global concern when hospitals in many developing countries began implementing shorter lengths of stay for uncomplicated deliveries. A mother's perceived readiness for hospital discharge may be influenced by many factors that can ultimately shape postdischarge outcomes. AIMS: The purpose of this study was to explore the antepartum, intrapartum, and postpartum predictors of discharge readiness, including nursing educational practices that are predictive of postpartum mothers' perceptions of readiness for hospital discharge...
February 22, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28225945/-satisfaction-and-perceived-quality-of-people-insured-by-the-social-health-protection-in-mexico-methodological-foundations
#13
Pedro J Saturno-Hernández, Juan Pablo Gutiérrez-Reyes, Waldo Ivan Vieyra-Romero, Martín Romero-Martínez, Gabriel Jaime O'Shea-Cuevas, Javier Lozano-Herrera, Sonia Tavera-Martínez, Mauricio Hernández-Ávila
Objective: To describe the conceptual framework and methods for implementation and analysis of the satisfaction survey of the Mexican System for Social Protection in Health. Materials and methods: We analyze the methodological elements of the 2013, 2014 and 2015 surveys, including the instrument, sampling method and study design, conceptual framework, and characteristics and indicators of the analysis. Results: The survey captures information on perceived quality and satisfaction...
November 2016: Salud Pública de México
https://www.readbyqxmd.com/read/28225839/-conceptual-and-methodological-issues-involved-in-the-research-field-of-diagnostic-reasoning
#14
Francisco N Di Persia
The psychopathological field is crossed by dilemmas that put in question its methodological, conceptual and philosophical filiations. Since the early works of Ey and Jaspers until recent work of Berrios it has been in question the position psychopathology has in the field of medicine in general, and in the field of psychiatry in particular, especially if it should follow the principles of natural science or if it has an autonomous position between them. This debate has led to two opposing positions facing two different models of psychopathology: the biomedical model and the socio-constructionist model...
May 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28225790/direct-and-indirect-effects-of-enablers-on-hiv-testing-initiation-and-retention-in-antiretroviral-treatment-and-aids-related-mortality
#15
Ali Safarnejad, Jose-Antonio Izazola-Licea
BACKGROUND: An enabling environment is believed to have significant and critical effects on HIV and AIDS program implementation and desired outcomes. This paper estimates the paths, directionality, and direct and indirect associations between critical enablers with antiretroviral treatment (ART) coverage and to AIDS-related mortality. METHODS: Frameworks that consider the role of enablers in HIV and AIDS programs were systematically reviewed to develop a conceptual model of interaction...
2017: PloS One
https://www.readbyqxmd.com/read/28225108/an-integrated-perspective-on-rna-aptamer-ligand-recognition-models-clearing-muddy-waters
#16
K McCluskey, J Carlos Penedo
Riboswitches are short RNA motifs that sensitively and selectively bind cognate ligands to modulate gene expression. Like protein receptor-ligand pairs, their binding dynamics are traditionally categorized as following one of two paradigmatic mechanisms: conformational selection and induced fit. In conformational selection, ligand binding stabilizes a particular state already present in the receptor's dynamic ensemble. In induced fit, ligand-receptor interactions enable the system to overcome the energetic barrier into a previously inaccessible state...
February 22, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28224459/effect-of-hallucinogens-on-unconditioned-behavior
#17
Adam L Halberstadt, Mark A Geyer
Because of the ethical and regulatory hurdles associated with human studies, much of what is known about the psychopharmacology of hallucinogens has been derived from animal models. However, developing reliable animal models has proven to be a challenging task due to the complexity and variability of hallucinogen effects in humans. This chapter focuses on three animal models that are frequently used to test the effects of hallucinogens on unconditioned behavior: head twitch response (HTR), prepulse inhibition of startle (PPI), and exploratory behavior...
February 22, 2017: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/28224276/preparedness-and-cancer-related-symptom-management-among-cancer-survivors-in-the-first-year-post-treatment
#18
Corinne R Leach, Alyssa N Troeschel, Dawn Wiatrek, Annette L Stanton, Michael Diefenbach, Kevin D Stein, Katherine Sharpe, Kenneth Portier
BACKGROUND: Many cancer survivors feel unprepared for the physical and psychosocial challenges that accompany the post-treatment care transition (i.e., re-entry phase), including management of cancer-related symptoms. Few studies have investigated personal and contextual factors associated with the extent of preparedness for re-entry or how they are related to cancer-related symptom management. PURPOSE: Data from the American Cancer Society's Cancer Survivor Transition Study examined (1) characteristics of breast, prostate, and colorectal cancer survivors (n = 1188) within the first year of completing treatment who are most and least prepared for re-entry; and (2) how preparedness level and other characteristics are related to cancer-related symptom management...
February 21, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/28224003/darwinism-for-the-genomic-age-connecting-mutation-to-diversification
#19
Xia Hua, Lindell Bromham
A growing body of evidence suggests that rates of diversification of biological lineages are correlated with differences in genome-wide mutation rate. Given that most research into differential patterns of diversification rate have focused on species traits or ecological parameters, a connection to the biochemical processes of genome change is an unexpected observation. While the empirical evidence for a significant association between mutation rate and diversification rate is mounting, there has been less effort in explaining the factors that mediate this connection between genetic change and species richness...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/28222910/agents-of-the-father-s-law-in-a-society-of-brothers-a-philosophic-and-psychoanalytic-perspective-on-legitimate-use-of-violence
#20
Efrat Even-Tzur, Uri Hadar
This paper explores subjective processes of "Agents of Law" - individuals who the state grants the authority to use violence - and the dissonance stemming from the contradictory demands posed on them as legitimate users of violence despite the societal taboo against violence. A conceptual model will be offered based on two theoretical legs, Lacanian psychoanalysis and political theories of legitimacy. Specifically, psychoanalytic ideas would serve to examine unconscious processes, subject position and various identifications related to the question of "self-legitimacy" of Agents of Law...
February 17, 2017: International Journal of Law and Psychiatry
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