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https://www.readbyqxmd.com/read/28338872/data-gathering-belief-flexibility-and-reasoning-across-the-psychosis-continuum
#1
Thomas Ward, Emmanuelle Peters, Mike Jackson, Fern Day, Philippa A Garety
Background: There is evidence for a group of nonclinical individuals with full-blown, persistent psychotic experiences (PEs) but no need-for-care: they are of particular importance in identifying risk and protective factors for clinical psychosis. The aim of this study was to investigate whether reasoning biases are related to PEs or need-for-care. Method: Two groups with persistent PEs (clinical; n = 74; nonclinical; n = 92) and a control group without PEs (n = 83) were compared on jumping-to-conclusions (JTC) and belief flexibility...
March 8, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28338407/optimizing-a-retention-strategy-with-young-people-for-brightlight-a-longitudinal-cohort-study-examining-the-value-of-specialist-cancer-care-for-young-people
#2
Rachel M Taylor, Natasha Aslam, Sarah Lea, Jeremy S Whelan, Lorna A Fern
PURPOSE: To maximize retention of participants in a longitudinal cohort study, we sought to understand young peoples' views about barriers and facilitators to continuing study participation. METHODS: Ten young people with a previous cancer diagnosis aged 15-24 participated in a 1 day workshop. The workshop used participatory methodology consisting of three exercises as follows: role play/scene setting; force field analysis of research participation in small groups; and focus group discussion...
March 24, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28336391/serum-high-c-reactive-protein-concentrations-are-related-to-the-intake-of-dietary-macronutrients-and-fiber-findings-from-a-large-representative-persian-population-sample
#3
Sayyed Saeid Khayyatzadeh, Seyyed Mohammad Reza Kazemi-Bajestani, Mohammad Bagherniya, Mehraneh Mehramiz, Maryam Tayefi, Mahmoud Ebrahimi, Gordon A Ferns, Mohammad Safarian, Majid Ghayour-Mobarhan
OBJECTIVE: Serum high-sensitivity CRP is a marker of inflammation and an independent predictor of chronic diseases. However, the effect of diet on serum hs-CRP is unclear. The aim of this study was to investigate the relationship between dietary macronutrient intake and serum hs-CRP. DESIGN AND METHODS: We recruited 9778 adults, aged 35-65years as part of the MASHAD study. Dietary intake was determined using 24-hour dietary recall and several biochemical parameters including serum hs-CRP were measured...
March 20, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28334286/differences-in-the-photosynthetic-plasticity-of-ferns-and-ginkgo-grown-in-experimentally-controlled-low-o2-co2-atmospheres-may-explain-their-contrasting-ecological-fate-across-the-triassic-jurassic-mass-extinction-boundary
#4
C Yiotis, C Evans-Fitz Gerald, J C McElwain
Background and Aims: Fluctuations in [CO 2 ] have been widely studied as a potential driver of plant evolution; however, the role of a fluctuating [O 2 ]:[CO 2 ] ratio is often overlooked. The present study aimed to investigate the inherent physiological plasticity of early diverging, extant species following acclimation to an atmosphere similar to that across the Triassic-Jurassic mass extinction interval (TJB, approx. 200 Mya), a time of major ecological change. Methods: Mature plants from two angiosperm ( Drimys winteri and Chloranthus oldhamii ), two monilophyte ( Osmunda claytoniana and Cyathea australis ) and one gymnosperm ( Ginkgo biloba ) species were grown for 2 months in replicated walk-in Conviron BDW40 chambers running at TJB treatment conditions of 16 % [O 2 ]-1900 ppm [CO 2 ] and ambient conditions of 21 % [O 2 ]-400 ppm [CO 2 ], and their physiological plasticity was assessed using gas exchange and chlorophyll fluorescence methods...
March 11, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28331178/habitat-filtering-and-exclusion-of-weak-competitors-jointly-explain-fern-species-assemblage-along-a-light-and-water-gradient
#5
Hui Zhang, Shidan Zhu, Robert John, Ronghua Li, Hui Liu, Qing Ye
Fern species are an important component of the diversity of forest plant communities, but very little is known about how fern communities assemble in different environments. In this study, we use multiple trait-based tests to examine the relationships between several key eco-physiological traits which are direct indicators of shade and drought tolerance, and the abundance of fern species in pine forest (PF), pine and mixed broad leaf forest (PMBF) and matured broad leaf forest (MBF) in southern China. These forests are characterized by decreasing light but increasing water availability during succession, and the fern communities correspondingly differ in species composition...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28330564/proteomic-analysis-of-stipe-explants-reveals-differentially-expressed-proteins-involved-in-early-direct-somatic-embryogenesis-of-the-tree-fern-cyathea-delgadii-sternb
#6
Lucyna Domżalska, Sylwia Kędracka-Krok, Urszula Jankowska, Małgorzata Grzyb, Mirosław Sobczak, Jan J Rybczyński, Anna Mikuła
Using cyto-morphological analysis of somatic embryogenesis (SE) in the tree fern Cyathea delgadii as a guide, we performed a comparative proteomic analysis in stipe explants undergoing direct SE. Plant material was cultured on hormone-free medium supplemented with 2% sucrose. Phenol extracted proteins were separated using two-dimensional gel electrophoresis (2-DE) and mass spectrometry was performed for protein identification. A total number of 114 differentially regulated proteins was identified during early SE, i...
May 2017: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/28325830/into-africa-molecular-phylogenetics-and-historical-biogeography-of-sub-saharan-african-woodferns-dryopteris
#7
Emily B Sessa, Aino Juslén, Henry Väre, Sally M Chambers
PREMISE OF THE STUDY: Our goal was to infer the phylogenetic relationships and historical biogeography of the genus Dryopteris with a focus on taxa in sub-Saharan Africa and neighboring islands. In general, little is known about the relationships between African fern species and their congeners in other geographic regions, and our aim was to determine whether the sub-Saharan African species of Dryopteris are monophyletic and evolved within Africa or arrived there via repeated dispersals into Africa from other regions...
March 21, 2017: American Journal of Botany
https://www.readbyqxmd.com/read/28318234/light-absorbing-brown-carbon-aerosol-constituents-from-combustion-of-indonesian-peat-and-biomass
#8
Sri Hapsari Budisulistiorini, Matthieu Riva, Michael Williams, Jing Chen, Masayuki Itoh, Jason Douglas Surratt, Mikinori Kuwata
Light-absorbing brown carbon (BrC) constituents of organic aerosol (OA) have been shown to significantly absorb ultra-violet (UV) and visible light, and thus, impact radiative forcing. However, molecular identification of the BrC constituents is still limited. In this study, we characterize BrC constituents at the molecular level in: i) aerosols emitted by combustion of peat, fern/leaf, and charcoal from Indonesia and ii) ambient aerosols collected in Singapore during the 2015 haze episode. Aerosols were analyzed using ultra-performance liquid chromatography interfaced to a diode array detector and electrospray ionization high-resolution quadrupole time-of-flight mass spectrometer (UPLC/DAD-(-)ESI-HR-QTOFMS) operated in the negative ion mode...
March 20, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28303735/what-can-nanosafety-learn-from-drug-development-the-feasibility-of-safety-by-design
#9
Rune Hjorth, Lilian van Hove, Fern Wickson
"Safety by design" (SbD) is an intuitively appealing concept that is on the rise within nanotoxicology and nanosafety research, as well as within nanotechnology research policy. It leans on principles established within drug discovery and development (DDD) and seeks to address safety early, as well as throughout product development. However, it remains unclear what the concept of SbD exactly entails for engineered nanomaterials (ENMs) or how it is envisioned to be implemented. Here, we review the concept as it is emerging in European research and compare its resemblance with the safety testing and assessment practices in DDD...
March 17, 2017: Nanotoxicology
https://www.readbyqxmd.com/read/28298344/the-assembly-of-ant-farmed-gardens-mutualism-specialization-following-host-broadening
#10
Guillaume Chomicki, Milan Janda, Susanne S Renner
Ant-gardens (AGs) are ant/plant mutualisms in which ants farm epiphytes in return for nest space and food rewards. They occur in the Neotropics and Australasia, but not in Africa, and their evolutionary assembly remains unclear. We here use phylogenetic frameworks for important AG lineages in Australasia, namely the ant genus Philidris and domatium-bearing ferns (Lecanopteris) and flowering plants in the Apocynaceae (Hoya and Dischidia) and Rubiaceae (Myrmecodia, Hydnophytum, Anthorrhiza, Myrmephytum and Squamellaria)...
March 15, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28295410/diversity-of-strategies-for-escaping-reactive-oxygen-species-production-within-photosystem-i-among-land-plants-p700-oxidation-system-is-prerequisite-for-alleviating-photoinhibition-in-photosystem-i
#11
Daisuke Takagi, Kimitsune Ishizaki, Hitomi Hanawa, Tomohito Mabuchi, Ginga Shimakawa, Hiroshi Yamamoto, Chikahiro Miyake
In land plants, photosystem (PS) I photoinhibition limits carbon fixation and causes growth defects. In addition, recovery from PSI photoinhibition takes much longer than PSII photoinhibition when the PSI core-complex is degraded by oxidative damage. Accordingly, PSI photoinhibition should be avoided in land plants, and land plants should have evolved mechanisms to prevent PSI photoinhibition. However, such protection mechanisms have not yet been identified, and it remains unclear whether all land plants suffer from PSI photoinhibition in the same way...
March 10, 2017: Physiologia Plantarum
https://www.readbyqxmd.com/read/28279810/madagascar-sheds-new-light-on-the-molecular-systematics-and-biogeography-of-grammitid-ferns-new-unexpected-lineages-and-numerous-long-distance-dispersal-events
#12
Lucie Bauret, Myriam Gaudeul, Michael A Sundue, Barbara S Parris, Tom A Ranker, France Rakotondrainibe, Sabine Hennequin, Jaona Ranaivo, Marc-André Selosse, Germinal Rouhan
Based on a worldwide phylogenetic framework filling the taxonomic gap of Madagascar and surrounding islands of the Western Indian Ocean (WIO), we revisited the systematics of grammitid fern species (Polypodiaceae). We also investigated the biogeographic origin of the extant diversity in Madagascar and estimated the relative influence of vicariance, long-distance dispersals (LDD) and in situ diversification. Phylogenetic inferences were based on five plastid DNA regions (atpB, rbcL, rps4-trnS, trnG-trnR, trnL-trnF) and the most comprehensive taxonomic sampling ever assembled (224 species belonging to 31 out of 33 recognized grammitids genera)...
March 6, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28278456/boosted-random-ferns-for-object-detection
#13
Michael Villamizar, Juan Andrade-Cetto, Alberto Sanfeliu, Francesc Moreno-Noguer
In this paper we introduce the Boosted Random Ferns (BRFs) to rapidly build discriminative classifiers for learning and detecting object categories. At the core of our approach we use standard random ferns, but we introduce four main innovations that let us bring ferns from an instance to a category level, and still retain efficiency. First, we define binary features on the histogram of oriented gradients-domain (as opposed to intensity-), allowing for a better representation of intra-class variability. Second, both the positions where ferns are evaluated within the sliding window, and the location of the binary features for each fern are not chosen completely at random, but instead we use a boosting strategy to pick the most discriminative combination of them...
March 1, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28263220/ectopic-pelvic-fibroid-in-a-woman-with-uterine-agenesis-and-mayer-rokitansky-k%C3%A3-ster-hauser-syndrome
#14
Thelina Amaratunga, Iain Kirkpatrick, Yi Yan, Fern Karlicki
Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare disorder characterized by aplasia or hypoplasia of the uterus and vagina due to arrest in the development of the müllerian ducts. Women with this syndrome have the normal 46 XX karyotype, normal female secondary sex characteristics, and primary amenorrhea. Only a few cases have been described in the literature where a fibroid develops from a rudimentary, nonfunctioning uterus in patients with MRKH syndrome. In even rarer instances, a fibroid can develop in patients with a congenitally absent uterus...
March 3, 2017: Ultrasound Quarterly
https://www.readbyqxmd.com/read/28262927/targeting-the-ras-signaling-pathway-as-a-potential-therapeutic-target-in-the-treatment-of-colorectal-cancer
#15
REVIEW
Afsane Bahrami, Seyed Mahdi Hassanian, Soodabeh ShahidSales, Zahra Farjami, Malihe Hasanzadeh, Kazem Anvari, Amir Aledavood, Mina Maftouh, Gordon A Ferns, Majid Khazaei, Amir Avan
The V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) is an important pathways that is frequently dysregulated in colorectal cancer (CRC). It is involved in the modulation of several downstream effectors, that include: Raf/Mek/Erk, PI3K/Akt, RalGDS/p38MAPK and Rac/Rho, and thereby influences tumorigenesis, the invasive behaviors of tumor cell, and resistance to therapy. There is growing evidence exploring the use of drugs that target these pathways in the treatment of CRC. Cetuximab has been approved for CRC patients without a KRAS mutation, or for EGFR-expressing metastatic CRC, although most of the patients have a mutation of KRAS and NRAS...
March 6, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28262604/radiocaesium-contamination-and-dose-rate-estimation-of-terrestrial-and-freshwater-wildlife-in-the-exclusion-zone-of-the-fukushima-dai-ichi-nuclear-power-plant-accident
#16
Shoichi Fuma, Sadao Ihara, Hiroyuki Takahashi, Osamu Inaba, Youji Sato, Yoshihisa Kubota, Yoshito Watanabe, Isao Kawaguchi, Tatsuo Aono, Haruhi Soeda, Satoshi Yoshida
To characterise the radioactive contamination of terrestrial and freshwater wildlife caused by the Fukushima Dai-ichi Nuclear Power Plant accident, biological samples, namely, fungi, mosses, plants, amphibians, reptiles, insects, molluscs, and earthworms, were collected mainly from the forests of the exclusion zone in the Fukushima Prefecture from 2011 to 2012. Caesium-134 and (137)Cs were detected by gamma spectrometry in almost all the samples. Fungi, ferns, and mosses accumulated high amounts of radiocaesium, as they did in Chernobyl, with (134)Cs + (137)Cs activity concentrations of 10(4)-10(6) Bq kg(-1) fresh mass (FM)...
March 2, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28258494/three-rings-for-the-evolution-of-plastid-shape-a-tale-of-land-plant-ftsz
#17
Christopher Grosche, Stefan A Rensing
Nuclear-encoded plant FtsZ genes are derived from endosymbiotic gene transfer of cyanobacteria-like genes. The green lineage (Chloroplastida) and red lineage (Rhodophyta) feature FtsZ1 and FtsZ2 or FtsZB and FtsZA, respectively, which are involved in plastid division. These two proteins show slight differences and seem to heteropolymerize to build the essential inner plastid division ring. A third gene, encoding FtsZ3, is present in glaucophyte and charophyte algae, as well as in land plants except ferns and angiosperms...
March 3, 2017: Protoplasma
https://www.readbyqxmd.com/read/28251889/emergence-of-a-novel-subclade-of-influenza-a-h3n2-virus-in-london-december-2016-to-january-2017
#18
Heli Harvala, Dan Frampton, Paul Grant, Jade Raffle, Ruth Bridget Ferns, Zisis Kozlakidis, Paul Kellam, Deenan Pillay, Andrew Hayward, Eleni Nastouli
We report the molecular investigations of a large influenza A(H3N2) outbreak, in a season characterised by sharp increase in influenza admissions since December 2016. Analysis of haemagglutinin (HA) sequences demonstrated co-circulation of multiple clades (3C.3a, 3C.2a and 3C.2a1). Most variants fell into a novel subclade (proposed as 3C.2a2); they possessed four unique amino acid substitutions in the HA protein and loss of a potential glycosylation site. These changes potentially modify the H3N2 strain antigenicity...
February 23, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28249355/monobodies-and-other-synthetic-binding-proteins-for-expanding-protein-science
#19
REVIEW
Fern Sha, Gabriel Salzman, Ankit Gupta, Shohei Koide
Synthetic binding proteins are constructed using nonantibody molecular scaffolds. Over the last two decades, in-depth structural and functional analyses of synthetic binding proteins have improved combinatorial library designs and selection strategies, which have resulted in potent platforms that consistently generate binding proteins to diverse targets with affinity and specificity that rival those of antibodies. Favorable attributes of synthetic binding proteins, such as small size, freedom from disulfide bond formation and ease of making fusion proteins, have enabled their unique applications in protein science, cell biology and beyond...
March 1, 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/28249174/reduced-severity-of-histopathological-lesions-in-mink-selected-for-tolerance-to-aleutian-mink-disease-virus-infection
#20
A Hossain Farid, Linda E Ferns
The objective of this study was to measure the effect of selection for tolerance on the severity of the Aleutian disease (AD) lesions in mink. Sensitivity and specificity of antibody detection in the blood by counter-immunoelectrophoresis (CIEP) relative to the presence of Aleutian mink disease virus (AMDV) in the spleen by PCR in naturally infected farmed mink were also estimated. Carcasses of 680 sero-positive (CIEP-P) black mink from 28 farms in Nova Scotia, Canada, and from 132 sero-negative (CIEP-N) mink from 14 of these farms were collected at pelting time...
February 16, 2017: Research in Veterinary Science
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