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Haemoglobin A1c

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https://www.readbyqxmd.com/read/29149618/effectiveness-of-a-patient-centred-empowerment-based-intervention-programme-among-patients-with-poorly-controlled-type-2-diabetes-a-randomised-controlled-trial
#1
Li Cheng, Janet W H Sit, Kai-Chow Choi, Sek-Ying Chair, Xiaomei Li, Yuning Wu, Junhong Long, Meihua Tao
BACKGROUND: Despite extensive efforts and advances in evidence-based diabetes management, poor glycaemic control still remains a challenge in many countries. There is a paucity of research addressing the needs of patients with poorly controlled type 2 diabetes, or exploring the effectiveness of empowerment-based interventions in this vulnerable population. OBJECTIVES: To evaluate the effectiveness of a patient-centred, empowerment-based programme on glycaemic control and self-management behaviours among patients with poorly controlled type 2 diabetes...
November 3, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29127341/classification-rule-for-5-year-cardiovascular-diseases-risk-using-decision-tree-in-primary-care-chinese-patients-with-type-2-diabetes-mellitus
#2
Eric Yuk Fai Wan, Daniel Yee Tak Fong, Colman Siu Cheung Fung, Esther Yee Tak Yu, Weng Yee Chin, Anca Ka Chun Chan, Cindy Lo Kuen Lam
Cardiovascular disease(CVD) is the leading cause of mortality among patients with type 2 diabetes mellitus(T2DM), and a risk classification model for CVD among primary care diabetic patients is pivotal for risk-based interventions and patient information. This study developed a simple tool for a 5-year CVD risk prediction for primary care Chinese patients with T2DM. A retrospective cohort study was conducted on 137,935 primary care Chinese T2DM patients aged 18-79 years without history of CVD between 1 January 2010 and 31 December 2010...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29122448/validating-the-association-between-plasma-tumour-necrosis-factor-receptor-1-levels-and-the-presence-of-renal-injury-and-functional-decline-in-patients-with-type-2-diabetes
#3
Alison Doody, Sabrina Jackson, Jessie A Elliott, Ronan J Canavan, C Godson, David Slattery, Patrick J Twomey, Malachi J McKenna, Carel W le Roux, Neil G Docherty
AIMS: Elevated plasma soluble tumour necrosis factor receptor 1 (TNFR1) predicts long-term progression of chronic kidney disease. We investigated the association between elevated TNFR1 and the presence of renal disease in patients with Type 2 diabetes mellitus registering a haemoglobin A1c (HbA1c) >48mmol/mol despite medical therapy. METHODS: Using sensitivity, specificity and regression analyses we interrogated the association between plasma TNFR1 and presence of chronic kidney disease as assessed by the presence of microalbuminuria and/or an estimated glomerular filtration rate of less than 60ml/min/1...
September 18, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29094753/antenatal-haemoglobin-a1c-centiles-does-one-size-fit-all
#4
Ruth C E Hughes, Jonathan A Williman, Joanna E Gullam
BACKGROUND: In New Zealand, haemoglobin A1c measurements are routinely offered at booking, preferably before 20 weeks gestation, to detect pre-existing hyperglycaemia. A haemoglobin A1c <5.9% (41 mmol/mol) is considered normal based on the reference range for the non-pregnant population. AIMS: To determine pregnancy-specific haemoglobin A1c centiles by gestation and ethnicity. MATERIALS AND METHODS: This is a population-based observational study of pregnancies uncomplicated by diabetes (pre-existing or gestational) with ≥1 haemoglobin A1c measurement...
November 2, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29090609/serum-cystatin-c-is-associated-with-subclinical-atherosclerosis-in-patients-with-type-2-diabetes-a-retrospective-study
#5
Yu Kyung Chung, Young Ju Lee, Kye Whon Kim, Ryu Kyoung Cho, Seung Min Chung, Jun Sung Moon, Ji Sung Yoon, Kyu Chang Won, Hyoung Woo Lee
BACKGROUND: The aim of this study was to investigate the association between the serum cystatin C level and cardiovascular disease risk in patients with type 2 diabetes mellitus. METHODS: We studied 523 patients with type 2 diabetes mellitus and calculated estimated 10-year risk of atherosclerotic cardiovascular disease (%). Subclinical atherosclerosis was defined as brachial-ankle pulse wave velocity ⩾1700 ms, indicating the presence of arterial stiffness. RESULTS: Cystatin C level was significantly higher in the subclinical atherosclerosis group (brachial-ankle pulse wave velocity ⩾ 1700 ms) than in the non-subclinical atherosclerosis group (brachial-ankle pulse wave velocity < 1700 ms) (7...
October 1, 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/29057963/impact-of-analytical-and-biological-variations-on-classification-of-diabetes-using-fasting-plasma-glucose-oral-glucose-tolerance-test-and-hba1c
#6
Jia Hui Chai, Stefan Ma, Derick Heng, Joanne Yoong, Wei-Yen Lim, Sue-Anne Toh, Tze Ping Loh
Historically, diabetes is diagnosed by measuring fasting (FPG) and two-hour post oral glucose load (OGTT) plasma concentration and interpreting it against recommended clinical thresholds of the patient. More recently, glycated haemoglobin A1c (HbA1c) has been included as a diagnostic criterion. Within-individual biological variation (CVi), analytical variation (CVa) and analytical bias of a test can impact on the accuracy and reproducibility of the classification of a disease. A test with large biological and analytical variation increases the likelihood of erroneous classification of the underlying disease state of a patient...
October 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29025080/exposure-to-perchlorate-nitrate-and-thiocyanate-and-prevalence-of-diabetes-mellitus
#7
Gang Liu, Geng Zong, Klodian Dhana, Yang Hu, Benjamin C Blount, Maria Morel-Espinosa, Qi Sun
Background: It is known that perchlorate, nitrate and thiocyanate have the property of inhibiting sodium iodide symporter. Animal studies have suggested that these compounds, especially perchlorate, might also interfere with insulin secretion. However, the association between their exposure and diabetes risk is largely unknown in humans. Methods: Among 11 443 participants (mean age 42.3 years) from the National Health and Nutritional Examination Survey 2001-14, urinary perchlorate, nitrate and thiocyanate were measured by using ion chromatography coupled with electrospray tandem mass spectrometry...
September 11, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28981442/effect-of-l-carnitine-on-diabetes-induced-changes-of-skeletal-muscles-in-rats
#8
Shereen M Samir, Amr M Abbas, Sally M Safwat, Hanaa G Elserougy
BACKGROUND: Patients with diabetes mellitus (DM) are at risk of experiencing chronic complications such as retinopathy, nephropathy and myopathy. We aimed to evaluate the effects of L-carnitine on type II DM (T2DM)-induced biochemical, contractile and pathological changes in skeletal muscles of rats. METHODS: Thirty-two male Sprague Dawley rats were divided into the control, control+L-carnitine, T2DM and T2DM+L-carnitine groups. Plasma levels of glucose, insulin, malondialdehyde and antioxidants such as reduced glutathione, catalase and superoxide dismutase, haemoglobin A1c (HbA1c), insulin sensitivity index (ISI) as well as the contractile properties of the gastrocnemius muscle were measured...
October 5, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/28978949/comparative-effectiveness-of-telemedicine-strategies-on-type-2-diabetes-management-a-systematic-review-and-network-meta-analysis
#9
Shaun Wen Huey Lee, Carina Ka Yee Chan, Siew Siang Chua, Nathorn Chaiyakunapruk
The effects of telemedicine strategies on the management of diabetes is not clear. This study aimed to investigate the impact of different telemedicine strategies on glycaemic control management of type 2 diabetes patients. A search was performed in 6 databases from inception until September 2016 for randomized controlled studies that examined the use of telemedicine in adults with type 2 diabetes. Studies were independently extracted and classified according to the following telemedicine strategies: teleeducation, telemonitoring, telecase-management, telementoring and teleconsultation...
October 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28977545/higher-levels-of-self-reported-sitting-time-is-associated-with-higher-risk-of-type-2-diabetes-independent-of-physical-activity-in-chile
#10
Ximena Díaz-Martínez, Lewis Steell, María Adela Martinez, Ana María Leiva, Carlos Salas-Bravo, Ana María Labraña, Eliana Duran, Carlos Cristi-Montero, Katherine M Livingstone, Alex Garrido-Méndez, Cristian Alvarez, Felipe Poblete-Valderrama, María Luisa Zagalaz, Pedro Valdivia-Moral, Liliana Cuadra, Natalia Ulloa, Naomi D Willis, Carlos A Celis-Morales
Background: Sitting behaviours have increased markedly during the last two decades in Chile. However, their associations with health outcomes such as diabetes have not been reported. Therefore, the aim of this study was to investigate the independent association of self-reported sitting time with diabetes-related markers and diabetes prevalence in Chile. Methods: This cross-sectional study included participants (aged ≥18 years) from the Chilean National Health Survey 2009-10 (n = 4457)...
July 28, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28975669/refractive-error-in-chinese-with-type-2-diabetes-and-its-association-with-glycaemic-control
#11
E Song, Deng-Juan Qian, Shan Wang, Cailian Xu, Chen-Wei Pan
BACKGROUND: The aim of this study was to determine the prevalence of refractive errors and their association with glycaemic control among adults with type 2 diabetes mellitus (T2DM) in eastern China. METHODS: A community-based survey, including 913 adults with T2DM aged 30 to 89 years, was conducted. Refractive error was assessed by autorefraction, after which subjective refraction was performed. Ocular biometric parameters were measured by non-contact partial coherence laser interferometry...
October 3, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28972196/relationship-between-glycated-haemoglobin-concentration-and-erythrocyte-survival-in-type-2-diabetes-mellitus-determined-by-a-modified-carbon-monoxide-breath-test
#12
Zhenhe Huang, Yajing Liu, Yanfang Mao, Wenwen Chen, Zhangang Xiao, Yangyang Yu
In clinical practice, an unexplained discordance between percentage hemoglobin A1c (HbA1c) and the progression of diabetes and its complication is observed. HbA1c is determined by blood glucose and red blood cell (RBC) lifespan. Whether RBC lifespan changes in diabetic patients remains undefined because of the lack of the convenient and accurate measuring method. In the present study, we aim to observe the RBC lifespan in type 2 diabetic patients with poor blood glucose control by endogenous carbon monoxide (CO) measurement using a rapid and simplified CO breath test machine...
October 3, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28960394/increased-prevalence-of-fracture-and-hypoglycaemia-in-young-adults-with-concomitant-type-1-diabetes-mellitus-and-coeliac-disease
#13
Eleanor P Thong, Phillip Wong, Anouk Dev, Peter R Ebeling, Helena J Teede, Frances Milat
BACKGROUND: Both Type 1 diabetes mellitus (T1DM) and coeliac disease (CD) are independently associated with reduced bone mineral density (BMD) and increased fracture risk. Whilst poorer glycaemic control and increased microvascular complications have been described, the literature examining bone health and fractures in adults with concomitant T1DM and CD (T1DM + CD) is limited. OBJECTIVE: To evaluate fracture prevalence and explore associations with glycaemic control, hypoglycaemia and microvascular disease in T1DM + CD compared with T1DM alone...
September 28, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28954185/psychological-interventions-for-diabetes-related-distress-in-adults-with-type-2-diabetes-mellitus
#14
REVIEW
Boon How Chew, Rimke C Vos, Maria-Inti Metzendorf, Rob Jpm Scholten, Guy Ehm Rutten
BACKGROUND: Many adults with type 2 diabetes mellitus (T2DM) experience a psychosocial burden and mental health problems associated with the disease. Diabetes-related distress (DRD) has distinct effects on self-care behaviours and disease control. Improving DRD in adults with T2DM could enhance psychological well-being, health-related quality of life, self-care abilities and disease control, also reducing depressive symptoms. OBJECTIVES: To assess the effects of psychological interventions for diabetes-related distress in adults with T2DM...
September 27, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28939342/the-effect-of-nurse-prescribers-on-glycaemic-control-in-type-2-diabetes-a-systematic-review-and-meta-analysis
#15
REVIEW
Maryam Tabesh, Dianna J Magliano, Digsu N Koye, Jonathan E Shaw
BACKGROUND: The creation of advanced nursing roles in diabetes management, with specific skills such as nurse prescribing, has resulted in nurses taking on roles that have traditionally been associated with doctors. OBJECTIVES: We aimed to examine the effectiveness of nurse-led clinics, in which nurses were involved in prescribing, on haemoglobin A1c (HbA1c) among people with type 2 diabetes. METHODS: We systematically searched the literature, Medline, the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE and Allied Health Literature database guide (CINAHL) databases, to identify randomised controlled trials (RCTs) assessing the effect of nurse prescribers on HbA1c...
August 31, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28923672/relationship-between-glycaemic-levels-and-arterial-stiffness-in-non-diabetic-adults
#16
Iván Cavero-Redondo, Vicente Martínez-Vizcaíno, Celia Álvarez-Bueno, José Ignacio Recio-Rodríguez, Manuel Ángel Gómez-Marcos, Luis García-Ortiz
OBJECTIVE: To examine, in a non-diabetic population, whether the association between arterial stiffness and glycaemic levels depends on the test used as a glycaemic indicator, fasting plasma glucose (FPG) or glycated haemoglobin A1c (HbA1c). PATIENT POPULATION AND METHODS: A cross-sectional analysis of a 220 non-diabetic subsample from the EVIDENT II study in which FPG, HbA1c and arterial stiffness-related parameters (pulse wave velocity, radial and central augmentation index, and central pulse pressure) were determined...
September 15, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28900367/measurement-of-hba1c-and-hba2-by-capillarys-2-flex-piercing-hba1c-programme-for-simultaneous-management-of-diabetes-and-screening-for-thalassemia
#17
Peifeng Ke, Jiawei Liu, Yan Chao, Xiaobin Wu, Yujuan Xiong, Li Lin, Zemin Wan, Xinzhong Wu, Jianhua Xu, Junhua Zhuang, Xianzhang Huang
INTRODUCTION: Thalassemia could interfere with some assays for haemoglobin A1c (HbA1c) measurement, therefore, it is useful to be able to screen for thalassemia while measuring HbA1c. We used Capillarys 2 Flex Piercing (Capillarys 2FP) HbA1c programme to simultaneously measure HbA1c and screen for thalassemia. MATERIALS AND METHODS: Samples from 498 normal controls and 175 thalassemia patients were analysed by Capillarys 2FP HbA1c programme (Sebia, France). For method comparison, HbA1c was quantified by Premier Hb9210 (Trinity Biotech, Ireland) in 98 thalassaemia patients samples...
October 1, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28855195/prevalence-and-risk-factors-for-diabetic-retinopathy-in-china-a-multi-hospital-based-cross-sectional-study
#18
Guihua Zhang, Haoyu Chen, Weiqi Chen, Mingzhi Zhang
PURPOSE: To determine the prevalence and risk factors for diabetic retinopathy (DR) and sight-threatening diabetic retinopathy (STDR) in a multi-hospital-based DR screening programme among patients with diabetes in China, the Lifeline Express Diabetic Retinopathy Screening Program. METHODS: Patients with diabetes in eight hospitals across mainland China (both southern and northern) from January 2014 to July 2016 were recruited in this programme. All participants underwent a standardised interview and examinations and received digital fundus photography...
August 30, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28836100/iron-a-strong-element-in-the-pathogenesis-of-chronic-hyperglycaemia-after-acute-pancreatitis
#19
Shayal K Chand, Ruma G Singh, Sayali A Pendharkar, Maxim S Petrov
Evidence shows an association between markers of iron metabolism and glucose metabolism in type 2 diabetes mellitus. Acute pancreatitis is the largest contributor to diabetes of the exocrine pancreas. However, the pathogenesis of new-onset pre-diabetes or diabetes after pancreatitis remains unclear. This study aimed to investigate associations between markers of iron metabolism and glucose metabolism following acute pancreatitis. Fasting blood samples were collected to analyse markers of glucose metabolism (haemoglobin A1c) and iron metabolism (hepcidin, ferritin, and soluble transferrin receptor)...
August 23, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28828047/type-1-diabetes-and-thyroid-autoimmunity-in-children
#20
Anca Orzan, Carmen Novac, Mihaiela Mihu, Constantin Ionescu Tirgoviste, Mihaela Balgradean
INTRODUCTION: Autoimmune thyroid disease and type 1 diabetes (T1DM) are two autoimmune diseases frequently associated, especially in pediatric population. Aims: we wanted to determine and ilustrate the relationship between type 1 diabetes and autoimmune thyroiditis and also the factors than can influence it, like gender, age, diabetes duration. Glycemic control was also evaluated for all the patients. MATERIAL AND METHODS: There were studied 256 patients, children and adolescents with T1DM (male/ female: 145/115; 55%/45%)...
December 2016: Mædica
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