Rocco Salvatore Calabrò, Margherita Russo, Antonino Naro, Rossella Ciurleo, Giangaetano D'Aleo, Carmela Rifici, Tina Balletta, Cristian La Via, Massimo Destro, Placido Bramanti, Edoardo Sessa
BACKGROUND: Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system, affecting ambulation even in people with only mild neurological signs. Patients with MS frequently experience spasticity, which contributes significantly to impair their motor functions, including ambulation, owing to muscle stiffness, spasms, and pain. OBJECTIVES: To clarify the role of delta-9-tetrahydrocannabinol(THC):cannabidiol(CBD) oromucosal spray, coupled to robot-aided gait training (RAGT) using the Lokomat©Pro to improve functional ambulation in patients with MS...
August 2020: Multiple Sclerosis and related Disorders