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https://www.readbyqxmd.com/read/29214994/human-liver-segments-role-of-cryptic-liver-lobes-and-vascular-physiology-in-the-development-of-liver-veins-and-left-right-asymmetry
#1
Jill P J M Hikspoors, Mathijs M J P Peeters, Nutmethee Kruepunga, Hayelom K Mekonen, Greet M C Mommen, S Eleonore Köhler, Wouter H Lamers
Couinaud based his well-known subdivision of the liver into (surgical) segments on the branching order of portal veins and the location of hepatic veins. However, both segment boundaries and number remain controversial due to an incomplete understanding of the role of liver lobes and vascular physiology on hepatic venous development. Human embryonic livers (5-10 weeks of development) were visualized with Amira 3D-reconstruction and Cinema 4D-remodeling software. Starting at 5 weeks, the portal and umbilical veins sprouted portal-vein branches that, at 6...
December 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29107360/yield-of-atrial-fibrillation-detection-with-textile-wearable-holter-from-the-acute-phase-of-stroke-pilot-study-of-crypto-af-registry
#2
Jorge Pagola, Jesus Juega, Jaume Francisco-Pascual, Angel Moya, Mireia Sanchis, Alejandro Bustamante, Anna Penalba, Maria Usero, Elisa Cortijo, Juan F Arenillas, Ana I Calleja, Maria Sandin-Fuentes, Jeronimo Rubio, Fernando Mancha, Irene Escudero-Martinez, Francisco Moniche, Reyes de Torres, Soledad Pérez-Sánchez, Carlos E González-Matos, Ángela Vega, Alonso A Pedrote, Eduardo Arana-Rueda, Joan Montaner, Carlos A Molina
BACKGROUND: We describe the feasibility of monitoring with a Textile Wearable Holter (TWH) in patients included in Crypto AF registry. METHODS: We monitored cryptogenic stroke patients from stroke onset (<3days) continuously during 28days. We employed a TWH composed by a garment and a recorder. We compared two garments (Lead and Vest) to assess rate of undiagnosed Atrial Fibrillation (AF) detection, monitoring compliance, comfortability (1 to 5 points), skin lesions, and time analyzed...
October 22, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29016974/blockchain-distributed-ledger-technologies-for-biomedical-and-health-care-applications
#3
Tsung-Ting Kuo, Hyeon-Eui Kim, Lucila Ohno-Machado
Objectives: To introduce blockchain technologies, including their benefits, pitfalls, and the latest applications, to the biomedical and health care domains. Target Audience: Biomedical and health care informatics researchers who would like to learn about blockchain technologies and their applications in the biomedical/health care domains. Scope: The covered topics include: (1) introduction to the famous Bitcoin crypto-currency and the underlying blockchain technology; (2) features of blockchain; (3) review of alternative blockchain technologies; (4) emerging nonfinancial distributed ledger technologies and applications; (5) benefits of blockchain for biomedical/health care applications when compared to traditional distributed databases; (6) overview of the latest biomedical/health care applications of blockchain technologies; and (7) discussion of the potential challenges and proposed solutions of adopting blockchain technologies in biomedical/health care domains...
November 1, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28963480/space-division-multiplexing-chip-to-chip-quantum-key-distribution
#4
Davide Bacco, Yunhong Ding, Kjeld Dalgaard, Karsten Rottwitt, Leif Katsuo Oxenløwe
Quantum cryptography is set to become a key technology for future secure communications. However, to get maximum benefit in communication networks, transmission links will need to be shared among several quantum keys for several independent users. Such links will enable switching in quantum network nodes of the quantum keys to their respective destinations. In this paper we present an experimental demonstration of a photonic integrated silicon chip quantum key distribution protocols based on space division multiplexing (SDM), through multicore fiber technology...
September 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28796209/blockchains-crypto-control-your-own-energy-supply
#5
Merlinda Andoni, Valentin Robu, David Flynn
No abstract text is available yet for this article.
August 9, 2017: Nature
https://www.readbyqxmd.com/read/28654242/global-cryptosporidium-loads-from-livestock-manure
#6
Lucie C Vermeulen, Jorien Benders, Gertjan Medema, Nynke Hofstra
Understanding the environmental pathways of Cryptosporidium is essential for effective management of human and animal cryptosporidiosis. In this paper we aim to quantify livestock Cryptosporidium spp. loads to land on a global scale using spatially explicit process-based modeling, and to explore the effect of manure storage and treatment on oocyst loads using scenario analysis. Our model GloWPa-Crypto L1 calculates a total global Cryptosporidium spp. load from livestock manure of 3.2 × 10(23) oocysts per year...
August 1, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28634143/pcr-based-verification-of-positive-rapid-diagnostic-tests-for-intestinal-protozoa-infections-with-variable-test-band-intensity
#7
Sören L Becker, Ivan Müller, Pascal Mertens, Mathias Herrmann, Leyli Zondie, Lindsey Beyleveld, Markus Gerber, Rosa du Randt, Uwe Pühse, Cheryl Walter, Jürg Utzinger
Stool-based rapid diagnostic tests (RDTs) for pathogenic intestinal protozoa (e.g. Cryptosporidium spp. and Giardia intestinalis) allow for prompt diagnosis and treatment in resource-constrained settings. Such RDTs can improve individual patient management and facilitate population-based screening programmes in areas without microbiological laboratories for confirmatory testing. However, RDTs are difficult to interpret in case of 'trace' results with faint test band intensities and little is known about whether such ambiguous results might indicate 'true' infections...
June 17, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28611482/infection-unlocking-the-crypto-drug-cabinet
#8
Katrina Ray
No abstract text is available yet for this article.
July 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28594836/enhancing-fish-underwater-visual-census-to-move-forward-assessment-of-fish-assemblages-an-application-in-three-mediterranean-marine-protected-areas
#9
Giulia Prato, Pierre Thiriet, Antonio Di Franco, Patrice Francour
Monitoring fish assemblages is needed to assess whether Marine Protected Areas (MPAs) are meeting their conservation and fisheries management goals, as it allows one to track the progress of recovery of exploited species and associated communities. Underwater Visual Census techniques (UVC) are used to monitor fish assemblages in MPAs. UVCs should be adapted to fish abundance, body-size and behaviour, which can strongly affect fish detectability. In Mediterranean subtidal habitats, however, UVC strip transects of one surface area (25x5 m2) are commonly used to survey the whole fish assemblage, from large shy fish to small crypto-benthic fish...
2017: PloS One
https://www.readbyqxmd.com/read/28572921/hydroxycinnamic-acids-in-cooked-potato-tubers-from-solanum-tuberosum-group-phureja
#10
Clara Piñeros-Niño, Carlos-Eduardo Narváez-Cuenca, Ajjamada C Kushalappa, Teresa Mosquera
Hydroxycinnamic acids are phenolic compounds and are considered to have health promotion properties due to their antioxidant activity. Potato tubers of 113 genotypes of Solanum tuberosum group Phureja belonging to the Colombian Central Collection, landraces of potatoes, and commercial cultivars were evaluated for their hydroxycinnamic acids content. The composition of these compounds was analyzed using cooked tubers in two different agro-climatic conditions. The genotypes were analyzed for chlorogenic acid, neo-chlorogenic acid, crypto-chlorogenic acid, and caffeic acid by ultrahigh-performance liquid chromatography (UHPLC)...
May 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28263756/neuregulin-1%C3%AE-induces-proliferation-survival-and-paracrine-signaling-in-normal-human-cardiac-ventricular-fibroblasts
#11
Annet Kirabo, Sergey Ryzhov, Manisha Gupte, Seng Sengsayadeth, Richard J Gumina, Douglas B Sawyer, Cristi L Galindo
Neuregulin-1β (NRG-1β) is critical for cardiac development and repair, and recombinant forms are currently being assessed as possible therapeutics for systolic heart failure. We previously demonstrated that recombinant NRG-1β reduces cardiac fibrosis in an animal model of cardiac remodeling and heart failure, suggesting that there may be direct effects on cardiac fibroblasts. Here we show that NRG-1β receptors (ErbB2, ErbB3, and ErbB4) are expressed in normal human cardiac ventricular (NHCV) fibroblast cell lines...
April 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28027812/new-psychoactive-substances-nps-on-cryptomarket-fora-an-exploratory-study-of-characteristics-of-forum-activity-between-nps-buyers-and-vendors
#12
Marie Claire Van Hout, Evelyn Hearne
BACKGROUND: The continual diversification of new psychoactive substances (NPS) circumventing legislation creates a public health and law enforcement challenge, and one particularly challenged by availability on Hidden Web cryptomarkets. METHODS: This is the first study of its kind which aimed to explore and characterise cryptomarket forum members' views and perspectives on NPS vendors and products within the context of Hidden Web community dynamics. An internal site search was conducted on two cryptomarkets popular with NPS vendors and hosting fora; Alphabay and Valhalla, using the search terms of 40 popular NPS in the seven categories of stimulant/cathinone; GABA activating; hallucinogen, dissociative, cannabinoid, opioid and other/unspecified/uncategorised NPS...
December 24, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27910979/efficient-synthesis-of-cysteine-rich-cyclic-peptides-through-intramolecular-native-chemical-ligation-of-n-hnb-cys-peptide-crypto-thioesters
#13
Victor P Terrier, Agnès F Delmas, Vincent Aucagne
We herein introduce a straightforward synthetic route to cysteine-containing cyclic peptides based on the intramolecular native chemical ligation of in situ generated thioesters. Key precursors are N-Hnb-Cys crypto-thioesters, easily synthesized by Fmoc-based SPPS. The strategy is applied to a representative range of naturally occurring cyclic disulfide-rich peptide sequences.
December 2, 2016: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/27908284/obscured-hemorrhagic-pancreatitis-after-orthotopic-heart-transplantation-complicated-with-acute-right-heart-failure-and-hepatic-dysfunction-a-case-report
#14
Ting-Wei Lin, Meng-Ta Tsai, Jun-Neng Roan, Yi-Sheng Liu, Hong-Ming Tsai, Chwan-Yau Luo
BACKGROUND: Pancreatitis is a serious complication after cardiac surgery and can lead to significant morbidities and mortality. The incidence of pancreatitis is even higher in patients undergoing heart transplantation than in those undergoing other cardiac surgeries. Nevertheless, the clinical presentations of pancreatitis are frequently atypical in these patients. CASE PRESENTATION: We report a heart recipient who was complicated with acute right heart failure initially after orthotopic heart transplantation and developed devastating unanticipated hemorrhagic pancreatitis 1 month after the transplantation...
December 1, 2016: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/27876910/low-sensitivity-of-the-immunocardstat-%C3%A2-crypto-giardia-rapid-assay-test-for-the-detection-of-giardia-and-cryptosporidium-in-fecal-samples-from-children-living-in-libreville-central-africa
#15
M K Bouyou-Akotet, M Owono-Medang, M N Moussavou-Boussougou, M Mabika Mamfoumbi, R Mintsa-Nguema, D P Mawili-Mboumba, M Kombila
Giardiasis and cryptosporidiosis are now recognized as neglected tropical parasitic diseases. The risk of their dissemination  in developing countries, such as Gabon, is increasing, due to urban crowding and poor sanitation. Accurate, simple and rapid diagnosis tools are thus necessary for the estimation of their real burden. The aim of this study was to evaluate the performances of the ImmunocardSTAT(®)Crypto/Giardia Rapid Assay test for the detection of Cryptosporidium (C.) spp. and Giardia (G.) duodenalis in children living in Libreville, Gabon...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27864361/causes-of-male-infertility-a-9-year-prospective-monocentre-study-on-1737-patients-with-reduced-total-sperm-counts
#16
M Punab, O Poolamets, P Paju, V Vihljajev, K Pomm, R Ladva, P Korrovits, M Laan
STUDY QUESTION: What are the primary causes of severe male factor infertility? SUMMARY ANSWER: Although 40% of all patients showed primary causes of infertility, which could be subdivided into three groups based on the severity of their effect, ~75% of oligozoospermia cases remained idiopathic. WHAT IS KNOWN ALREADY: There are few large-scale epidemiological studies analyzing the causes of male factor infertility. STUDY DESIGN, SIZE, DURATION: A prospective clinical-epidemiological study was conducted at the Andrology Centre, Tartu University Hospital between 2005 and 2013, recruiting male partners of couples failing to conceive a child for over ≥12 months...
January 2017: Human Reproduction
https://www.readbyqxmd.com/read/27805411/n-sulfanylethylaminooxybutyramide-seaoxy-a-crypto-thioester-compatible-with-fmoc-solid-phase-peptide-synthesis
#17
Shugo Tsuda, Masayoshi Mochizuki, Ken Sakamoto, Masaya Denda, Hideki Nishio, Akira Otaka, Taku Yoshiya
An N-sulfanylethylaminooxybutyramide (SEAoxy) has been developed as a novel thioester equivalent for native chemical ligation. SEAoxy peptide was straightforwardly synthesized by conventional Fmoc solid-phase peptide synthesis without a problem. Moreover, SEAoxy peptide could be directly applied to native chemical ligation owing to the intramolecular N-to-S acyl shift that releases the peptide-thioester in situ. This methodology was successfully applied to the synthesis of two bioactive peptides.
November 18, 2016: Organic Letters
https://www.readbyqxmd.com/read/27760168/abundance-and-diversity-of-crypto-and-necto-benthic-coastal-fish-are-higher-in-marine-forests-than-in-structurally-less-complex-macroalgal-assemblages
#18
Pierre D Thiriet, Antonio Di Franco, Adrien Cheminée, Paolo Guidetti, Olivier Bianchimani, Solène Basthard-Bogain, Jean-Michel Cottalorda, Hazel Arceo, Joan Moranta, Pierre Lejeune, Patrice Francour, Luisa Mangialajo
In Mediterranean subtidal rocky reefs, Cystoseira spp. (Phaeophyceae) form dense canopies up to 1 m high. Such habitats, called 'Cystoseira forests', are regressing across the entire Mediterranean Sea due to multiple anthropogenic stressors, as are other large brown algae forests worldwide. Cystoseira forests are being replaced by structurally less complex habitats, but little information is available regarding the potential difference in the structure and composition of fish assemblages between these habitats...
2016: PloS One
https://www.readbyqxmd.com/read/27649390/immunopathological-characterization-of-cryptoglandular-anal-fistula-a-pilot-study-investigating-its-pathogenesis
#19
C Ratto, F Litta, D Lucchetti, A Parello, A Boninsegna, V Arena, L Donisi, F Calapà, A Sgambato
AIM: The pathogenesis of cryptoglandular anal fistula (AF) is still under debate. Tissue inflammation could play a primary role. The pathological process of epithelial mesenchymal transition (EMT) might be involved but has never been investigated. METHOD: In a prospective pilot study, 12 patients with an AF had a fistulectomy. The excised track was divided into proximal (intrasphincteric) and distal (extrasphincteric) parts which were subjected to standard histopathological examination...
December 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27561753/crypto-watermarking-of-transmitted-medical-images
#20
Ali Al-Haj, Ahmad Mohammad, Alaa' Amer
Telemedicine is a booming healthcare practice that has facilitated the exchange of medical data and expertise between healthcare entities. However, the widespread use of telemedicine applications requires a secured scheme to guarantee confidentiality and verify authenticity and integrity of exchanged medical data. In this paper, we describe a region-based, crypto-watermarking algorithm capable of providing confidentiality, authenticity, and integrity for medical images of different modalities. The proposed algorithm provides authenticity by embedding robust watermarks in images' region of non-interest using SVD in the DWT domain...
February 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
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