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Mental fatigue

Tobias Otto, Fred R H Zijlstra, Rainer Goebel
Investing mental effort is costly, and the investment has to be matched by a reward to make a person engage in task performance. However, the neural structures underlying the continued management of mental effort are not known. Previous work has identified left-lateralized structures, most prominently the left anterior Insular Cortex (aIC) as regions implied in post-hoc evaluation and also anticipation of mental effort investment. We present a study aimed at identifying neural structures that are sensitive to changes in both task load and fatigue-induced state load...
2018: PloS One
Aashish N Patel, Michael D Howard, Shane M Roach, Aaron P Jones, Natalie B Bryant, Charles S H Robinson, Vincent P Clark, Praveen K Pilly
Mental state monitoring is a critical component of current and future human-machine interfaces, including semi-autonomous driving and flying, air traffic control, decision aids, training systems, and will soon be integrated into ubiquitous products like cell phones and laptops. Current mental state assessment approaches supply quantitative measures, but their only frame of reference is generic population-level ranges. What is needed are physiological biometrics that are validated in the context of task performance of individuals...
2018: Frontiers in Human Neuroscience
Patrick N Mwangala, Symon M Kariuki, Moses K Nyongesa, Paul Mwangi, Esther Chongwo, Charles R Newton, Amina Abubakar
Epilepsy is frequently associated with neurocognitive impairments, mental health, and psychosocial problems but these are rarely documented in low- and middle-income countries. The aim of this study was to examine the neurocognitive outcomes, depressive symptoms, and psychosocial adjustments of people with epilepsy (PWE) in Kilifi, Kenya. We evaluated the impact of these outcomes on health-related quality of life. Self-report, interviewer-administered measures of depression (Major Depression Inventory) and quality of life (RAND SF-36) were administered to 63 PWE and 83 community controls...
June 12, 2018: Epilepsy & Behavior: E&B
Tom E Nightingale, Peter C Rouse, Jean-Philippe Walhin, Dylan Thompson, James L J Bilzon
OBJECTIVE: To assess the influence of a home-based exercise intervention on indices of health-related quality of life (HRQOL) in persons with spinal cord injury (SCI). DESIGN: This was a randomized controlled trial (HOMEX-SCI; ISRCTN57096451). After baseline laboratory testing and a week of free-living physical activity monitoring, eligible participants were randomly assigned (2:1 allocation ratio) to a home-based moderate-intensity upper-body exercise intervention (INT, n = 13), or a lifestyle maintenance control group (CON, n = 8), for 6 weeks...
June 11, 2018: Archives of Physical Medicine and Rehabilitation
Linbo Wei, Juan Li, Yanpei Cao, Jianming Xu, Wei Qin, Huijuan Lu
So far, liver transplantation (LT) has become the most effective way to treat end-stage liver-related diseases. As we all know, a stable caregiver is crucial to LT recovery. However, compared with LT patients, few studies were focused on LT caregivers.This study aimed to describe the quality of life (QoL), care burden, and their related factors in caregivers of LT patients in Shanghai, China.We collected 225 liver transplanted patients and their corresponding caregivers' social demographic and medical information; meanwhile, we assessed 225 LT recipients' caregivers' life quality; by using Caregiver Quality of Life Index-Liver Transplantation in Chinese version (CQOLC-LT), Zarit caregiver burden inventory in Chinese version (ZBI) was used to access the care burden...
June 2018: Medicine (Baltimore)
J Carl Pallais, Andrew Z Fenves, Michael T Lu, Krzysztof Glomski
New England Journal of Medicine, Volume 378, Issue 24, Page 2322-2333, June 2018.
June 14, 2018: New England Journal of Medicine
Elizabeth Armitage-Chan, Stephen A May
Professional studies teaching in medical and veterinary education is undergoing a period of change. Traditional approaches, aiming to teach students professional values and behaviors, are being enhanced by curricula designed to support students' professional identity formation. This development offers the potential for improving student engagement and graduates' mental well-being. The veterinary professional identity associated with emotional resilience and success in practice incorporates complexity in professional decision making and the importance of context on behaviors and actions...
June 13, 2018: Journal of Veterinary Medical Education
Salene M W Jones, Rana Salem, Dagmar Amtmann
Background: People with multiple sclerosis (MS) are at increased risk for depression and anxiety. The symptoms of MS are often similar to the somatic or physical symptoms of depression and anxiety (fatigue, trouble concentrating). This study examined whether MS symptoms and effects biased the assessment of somatic symptoms of anxiety and depression. Methods: People with MS (n = 513) completed a survey about MS symptoms, treatments, and distress. The Patient Health Questionnaire-9 assessed depression, and the patient-report version of the Primary Care Evaluation of Mental Disorders assessed anxiety...
May 2018: International Journal of MS Care
Christina Sandlund, Jerker Hetta, Gunnar H Nilsson, Mirjam Ekstedt, Jeanette Westman
BACKGROUND: People typically seek primary health care for daytime symptoms and impairments they experience in association with their insomnia. However, few studies address the question of whether insomnia treatment can improve such symptomatology. OBJECTIVES: To investigate whether a nurse-led group treatment program, based on the techniques of cognitive behavioral therapy for insomnia (CBT-I), improved daytime symptomatology in primary care patients with insomnia...
May 24, 2018: International Journal of Nursing Studies
Judy Edworthy, Scott Reid, Katie Peel, Samantha Lock, Jessica Williams, Chloe Newbury, Joseph Foster, Martin Farrington
Very little is known about people's ability to localize sound under varying workload conditions, though it would be expected that increasing workload should degrade performance. A set of eight auditory clinical alarms already known to have relatively high localizability (the ease with which their location is identified) when tested alone were tested in six conditions where workload was varied. Participants were required to indicate the location of a series of alarms emanating at random from one of eight speaker locations...
October 2018: Applied Ergonomics
Heide Götze, Norbert Köhler, Sabine Taubenheim, Florian Lordick, Anja Mehnert
OBJECTIVES: Although the median age at cancer diagnosis is about 70 years, few studies have evaluated physical and mental health in older patients. The main objectives of our study are to provide information about depression, functional disabilities and symptom burden in older hematological cancer patients (HCP), compared to a community sample (CS) of older individuals. MATERIALS AND METHODS: We conducted a prospective study with interview assessments at a meantime of 26 month (range 1-60) after diagnosis or relapse of hematologic cancer (ICD: C81 - C96)...
June 4, 2018: Journal of Geriatric Oncology
Susanne Fischer, Charlotte Markert, Jana Strahler, Johanna M Doerr, Nadine Skoluda, Mattes Kappert, Urs M Nater
Objective: Fatigue is a core feature of functional somatic syndromes (FSS). Fatigue is also prominent in patients with thyroid diseases, which is unsurprising given the role of the hypothalamic-pituitary-thyroid (HPT) axis in regulating physiological energy demands. Research in healthy women has shown that early life adversity is linked with alterations in the HPT axis. In view of the substantial prevalence of early life adversity in patients with FSS, our aim was to investigate whether HPT functioning is related to (a) fatigue, and (b) early life adversity in these patients...
2018: Frontiers in Physiology
Dena Sadeghi Bahmani, Leila Esmaeili, Vahid Shaygannejad, Markus Gerber, Juerg Kesselring, Undine E Lang, Edith Holsboer-Trachsler, Serge Brand
Background: Previous research of patients with multiple sclerosis (MS) focused prevalently on fatigue, depression, and cognitive dysfunction during the clinical course. By contrast, research on the longer-term characteristics of physical activity (PA), psychological functioning, and sleep problems is scarce. The aims of the present study were therefore to examine changes in PA, mental toughness (MT) as a proxy of psychological functioning, and sleep disturbances over a 2-year period of time after disease onset...
2018: Frontiers in Psychiatry
Federica Gevi, Giuseppina Fanelli, Lello Zolla
Male hypogonadism associated with insulin resistance (IR) very often leads to metabolic syndrome, at variance with hypogonadism in its first stadium of insulin sensitivity (IS). A plasma metabolomic investigation of these patients can provide useful information in comparison with the values of IS patients. To this aim plasma from insulin-resistant males with hypogonadism were analysed by using ultra high-performance liquid chromatography (UHPLC) and high-resolution mass spectrometry (HRMS). Thus, metabolites were compared to the controls through multivariate statistical analysis and grouped by metabolic pathways...
April 22, 2018: Cell Death & Disease
Marieke van Leeuwen, Olga Husson, Paola Alberti, Juan Ignacio Arraras, Olivier L Chinot, Anna Costantini, Anne-Sophie Darlington, Linda Dirven, Martin Eichler, Eva B Hammerlid, Bernhard Holzner, Colin D Johnson, Meropi Kontogianni, Trille Kristina Kjær, Ofir Morag, Sandra Nolte, Andrew Nordin, Andrea Pace, Monica Pinto, Katja Polz, John Ramage, Jaap C Reijneveld, Samantha Serpentini, Krzysztof A Tomaszewski, Vassilios Vassiliou, Irma M Verdonck-de Leeuw, Ingvild Vistad, Teresa E Young, Neil K Aaronson, Lonneke V van de Poll-Franse
BACKROUND: The number of cancer survivors is growing steadily and increasingly, clinical trials are being designed to include long-term follow-up to assess not only survival, but also late effects and health-related quality of life (HRQOL). Therefore it is is essential to develop patient-reported outcome measures (PROMs) that capture the full range of issues relevant to disease-free cancer survivors. The objectives of this project are: 1) to develop a European Organisation for Research and Treatment of Cancer (EORTC) questionnaire that captures the full range of physical, mental and social HRQOL issues relevant to disease-free cancer survivors; and 2) to determine at which minimal time since completion of treatment the questionnaire should be used...
June 4, 2018: Health and Quality of Life Outcomes
Ahrang Jung, Matthew E Nielsen, Jamie L Crandell, Mary H Palmer, Ashley Leak Bryant, Sophia K Smith, Deborah K Mayer
BACKGROUND: Non-muscle-invasive bladder cancer (NMIBC) represents approximately 75% of newly diagnosed patients with bladder cancer. Non-muscle-invasive bladder cancer survivors have unique chronic burdens including frequent recurrences, repeated surveillance cystoscopies and treatments, and the highest lifetime medical cost per person among all cancers. OBJECTIVE: The purpose of this study was to summarize studies assessing quality of life (QOL) in NMIBC survivors...
June 1, 2018: Cancer Nursing
Katie Bechman, Fang En Sin, Fowzia Ibrahim, Sam Norton, Faith Matcham, David Lloyd Scott, Andrew Cope, James Galloway
Background: Tapering of anti-tumour necrosis factor (TNF) therapy appears feasible, safe and effective in selected patients with rheumatoid arthritis (RA). Depression is highly prevalent in RA and may impact on flare incidence through various mechanisms. This study aims to investigate if psychological states predict flare in patients' dose tapering their anti-TNF therapy. Methods: This study is a post-hoc analysis of the Optimizing TNF Tapering in RA trial, a multicentre, randomised, open-label study investigating anti-TNF tapering in RA patients with sustained low disease activity...
2018: RMD Open
H J G Abrahams, M F M Gielissen, C A H H V M Verhagen, H Knoop
Severe fatigue occurs in one in four breast cancer survivors (BCS). Quality of life (QOL) and psychological factors are important in fatigue-oriented interventions for BCS, but an up-to-date overview is lacking. The aims of this review were to (i) provide a comprehensive overview of the relationship of fatigue with QOL and factors that can be addressed in psychological interventions for fatigue in BCS and (ii) determine the strength of evidence for these relationships. A systematic literature search was conducted to find studies on fatigue in BCS who had completed curative breast cancer treatment...
May 17, 2018: Clinical Psychology Review
P De Roa, P Paris, J L Poindessous, O Maillet, A Héron
Fibromyalgia is a chronic widespread pain syndrome associated with chronic fatigue. Its pathogenesis is not clearly understood. This study presents subjective experiences and sensitivities reported by fibromyalgia patients, which should be considered in primary care to avoid medical nomadism, as well as stigmatization of the patients. The prevalence of significant characteristics was compared with others patients consulting at the same pain unit who suffer from rebel and disabling form of chronic migraine. Psychometric tests were anonymously completed by 78 patients of the Pain Unit (44 fibromyalgia patients and 34 migraine patients)...
2018: Pain Research & Management: the Journal of the Canadian Pain Society
Q Feng
Objective: To analyze the correlation between obstructive sleep apnea syndrome (OSAHS) and cognitive impairment and functional status after stroke. Method: From February 2014 to September 2016, a total of 189 patients were included in the study, 33 patients with mild OSAHS were excluded, and finally 86 patients in the study group and 70 patients in the control group were included in the final analysis. The main indicators included the cognitive and functional status. Cognitive status was assessed by nine dimensions: vigilance, attention, memory, working memory, executive, language, insight, mental activity, psychomotor, and intelligence...
July 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
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