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Laser in dermatology

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https://www.readbyqxmd.com/read/29448838/novel-methotrexate-soft-nanocarrier-fractional-erbium-yag-laser-combination-for-clinical-treatment-of-plaque-psoriasis
#1
Shahenda A Ramez, Mona M Soliman, Maha Fadel, Faisal Nour El-Deen, Maha Nasr, Eman R Youness, Dalea M Aboel-Fadl
Psoriasis is a commonly encountered chronic dermatological disease, presenting with inflammatory symptoms in patients. Systemic treatment of psoriasis is associated with several adverse effects, therefore the development of a customized topical treatment modality for psoriasis would be an interesting alternative to systemic delivery. The therapeutic modality explored in this article was the comparative treatment of psoriatic patients using nanoparticulated methotrexate in the form of jojoba oil-based microemulsion with or without fractional erbium YAG laser...
February 15, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29434427/picosecond-laser-treatment-for-tattoos-and-benign-cutaneous-pigmented-lesions-secondary-publication
#2
REVIEW
Kenichiro Kasai
Background and aims: The selective removal of tattoos and benign cutaneous pigmented lesions with laser energy evolved rapidly with the development of the nanosecond-domain Q-switched laser (ns-laser). Recently, however, a series of picosecond-domain lasers (ps-lasers) with pulsewidths less than 1 ns has become commercially available, enabling more efficient and faster removal of pigmented lesions in the field of dermatologic laser surgery. Rationale behind the ps-laser: The efficacy of the ns-laser depended on the theory of selective photothermolysis, whereby an extremely short pulse width was delivered less than the thermal relaxation time (TRT) of a target...
December 31, 2017: Laser Therapy
https://www.readbyqxmd.com/read/29431372/pigmentation-disorders-diagnosis-and-management
#3
Scott Plensdorf, Maria Livieratos, Nabil Dada
Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules. These conditions are generally benign but can be distressing to patients. Appropriate dermatologic history, skin examination, and skin biopsy, when appropriate, can help exclude melanoma and its precursors. In addition to addressing the underlying condition, hyperpigmentation is treated with topical agents, chemical peels, cryotherapy, light or laser therapy, or a combination of these methods...
December 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29400580/picosecond-alexandrite-laser-is-superior-to-q-switched-nd-yag-laser-in-treatment-of-minocycline-induced-hyperpigmentation-a-case-study-and-review-of-the-literature
#4
Tom Barrett, Sally de Zwaan
Minocycline is a commonly prescribed tetracycline antibiotic used for the treatment of a number of dermatological conditions including acne and rosacea. Long-term adverse effects of minocycline include cutaneous hyperpigmentation. Various treatment options have been suggested for the treatment of minocycline pigmentation. We report a case of a patient on long-term low-dose minocycline for the treatment of rosacea with type III minocycline hyperpigmentation. A comparison was made between Q-Switch Nd:YAG and picosecond laser over a nine 9-period with treatments spaced 1 month apart, with a clearance in the patient pigmentation after four treatments with picosecond laser...
February 5, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29399265/efficacy-of-fractional-carbon-dioxide-laser-in-the-treatment-of-mature-burn-scars-a-clinical-histopathological-and-histochemical-study
#5
Khaled El-Hoshy, Mona R E Abdel-Halim, Dina Dorgham, Safinaz Salah El-Din Sayed, Mona El-Kalioby
OBJECTIVE: The purpose of this study was to evaluate the efficacy of fractional carbon dioxide laser use in the treatment of mature burn scars. DESIGN: This was an uncontrolled, open-label clinical trial. SETTING: The setting for this study was Dermatology Department at Cairo University in Cairo, Egypt. PARTICIPANTS: Twenty patients with mature burn scars were included in the study. MEASUREMENTS: Three fractional carbon dioxide laser sessions were given, 4 to 8 weeks apart. Primary outcome was measured using two scar scales, the Vancouver Scar Scale and the Patient and Observer Scar Assessment Scale...
December 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29386831/terminal-deoxynucleotidyl-transferase-mediated-deoxyuridine-triphosphate-nick-end-labeling-tunel-assay-to-characterize-histopathologic-changes-following-thermal-injury
#6
Ji Min Lee, Ji Hyun Park, Bo Young Kim, Il-Hwan Kim
Background: Despite the wide application of lasers and radiofrequency (RF) surgery in dermatology, it is difficult to find studies showing the extent of damage dependent on cell death. Objective: We evaluated histopathologic changes following in vivo thermal damage generated by CO2 laser, 1,444 nm long-pulsed neodymium:yttrium-aluminum-garnet (LP Nd:YAG) laser and RF emitting electrosurgical unit. Methods: Thermal damage was induced by the above instruments on ventral skin of rat...
February 2018: Annals of Dermatology
https://www.readbyqxmd.com/read/29369914/a-single-center-randomized-double-blind-placebo-controlled-clinical-trial-of-the-effectiveness-of-ant1-soybean-extract-cream-on-skin-recovery-after-nd-yag-laser-treatment
#7
Meng-Chien Hsieh, Yi-Chia Wu, Shu-Hung Huang, Yur-Ren Kuo, Su-Shin Lee
Nd:YAG laser has been used extensively for its versatility in treating many common aesthetic problems, but numerous adverse effects are often complained by recipients of Nd:YAG laser. This study introduces the ANT1 soybean extract cream, which was formulated to alleviate adverse effects after laser therapy. This study explores whether ANT1 enhances the repair mechanism of the postlaser skin, decreases laser-induced complication, and shortens recovery time. The study also aims to pinpoint the ANT1 concentration that is most effective in improving the skin condition after Nd-YAG laser therapy...
January 25, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29356051/optical-coherence-tomography-angiography-of-normal-skin-and-inflammatory-dermatologic-conditions
#8
Anthony J Deegan, Faezeh Talebi-Liasi, Shaozhen Song, Yuandong Li, Jingjiang Xu, Shaojie Men, Michi M Shinohara, Mary E Flowers, Stephanie J Lee, Ruikang K Wang
BACKGROUND: In clinical dermatology, the identification of subsurface vascular and structural features known to be associated with numerous cutaneous pathologies remains challenging without the use of invasive diagnostic tools. OBJECTIVE: To present an advanced optical coherence tomography angiography (OCTA) method to directly visualize capillary-level vascular and structural features within skin in vivo. METHODS: An advanced OCTA system with a 1310 nm wavelength was used to image the microvascular and structural features of various skin conditions...
January 22, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29356026/light-emitting-diodes-in-dermatology-a-systematic-review-of-randomized-controlled-trials
#9
Jared Jagdeo, Evan Austin, Andrew Mamalis, Christopher Wong, Derek Ho, Daniel Siegel
OBJECTIVE: In dermatology, patient and physician adoption of light-emitting diode (LED) medical technology continues to grow as research indicates that LEDs may be used to treat skin conditions. The goal of this systematic review is to critically analyze published randomized controlled trials (RCTs) and provide evidence-based recommendations on the therapeutic uses of LEDs in dermatology based on published efficacy and safety data. METHODS: A systematic review of the published literature on the use of LED treatments for skin conditions was performed on September 13th 2017...
January 22, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29352492/variability-of-pulsed-energy-outputs-from-three-dermatology-lasers-during-multiple-simulated-treatments
#10
J Britton
BACKGROUND: Dermatology laser treatments are undertaken at regional departments using lasers of different powers and wavelengths. In order to achieve good outcomes there need to be good consistency of laser output across different weeks as it is custom and practice to break down the treatments into individual fractions. Departments will also collect information from test patches to help decide on the most appropriate treatment parameters for individual patients. OBJECTIVES: The objective of these experiments is to assess the variability of the energy outputs from a small number of lasers across multiple weeks at realistic parameters...
January 20, 2018: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/29331035/noninvasive-optical-spectroscopy-for-identification-of-non-melanoma-skin-cancer-pilot-study
#11
David J Carpenter, Mirabelle B Sajisevi, Nikita Chapurin, Clifford Scott Brown, Tracy Cheng, Gregory M Palmer, Daniel S Stevenson, Caroline L Rao, Russell P Hall, Charles R Woodard
OBJECTIVE: Optical spectroscopy offers a noninvasive alternative to biopsy as a first-line screening tool for suspicious skin lesions. This study sought to define several optical parameters across malignant and benign tissue types. STUDY DESIGN: Prospective pilot trial utilizing the Zenalux IM1 optical spectroscopy device from April 2016 to February 2017. For each skin lesion, provider pre-biopsy probability of malignancy was compared to histolopathologic diagnosis...
January 13, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29291276/a-hairy-situation-laser-hair-removal-after-oral-reconstruction
#12
Bridget E Shields, Molly S Moye, Rodrigo Bayon, Steven M Sperry, Karolyn A Wanat
OBJECTIVES: To present a case series of 4 patients who underwent postoperative hair removal using the long-pulsed Alexandrite or Nd:YAG laser following intraoral cutaneous flap reconstruction. METHODS: Patients underwent epilation in dermatology clinic with long-pulsed Alexandrite or Nd:YAG lasers, spaced 8 weeks apart, until hair removal was achieved. RESULTS: All patients achieved improvement in hair removal regardless of initial flap donor site with significant improvement in quality of life and minimal side effects...
December 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29243020/effect-of-1064-nm-q-switched-nd-yag-laser-on-invasiveness-and-innate-immune-response-in-keratinocytes-infected-with-candida-albicans
#13
Baroni Adone, De Filippis Anna, Oliviero Giovanni, Fusco Alessandra, Perfetto Brunella, Buommino Elisabetta, Donnarumma Giovanna
Candida albicans is an opportunistic pathogen commensal in the oral cavity, vagina, and healthy skin. Common therapeutic options for fungal infections are topical or systemic antifungal drugs. Recently, in cutaneous pathologies, lasers and light-based treatments have emerged showing few contraindications and minimal side effects. The Q-switched (Nd-YAG) laser at a wavelength of 1064 nm has been shown to be useful in dermatology, dentistry, and some other medical specialties. It is used to treat onychomycoses, warts, and wounds and in some other treatments...
December 14, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29185292/long-ranging-swept-source-optical-coherence-tomography-based-angiography-outperforms-its-spectral-domain-counterpart-in-imaging-human-skin-microcirculations
#14
Jingjiang Xu, Shaozhen Song, Shaojie Men, Ruikang K Wang
There is an increasing demand for imaging tools in clinical dermatology that can perform in vivo wide-field morphological and functional examination from surface to deep tissue regions at various skin sites of the human body. The conventional spectral-domain optical coherence tomography-based angiography (SD-OCTA) system is difficult to meet these requirements due to its fundamental limitations of the sensitivity roll-off, imaging range as well as imaging speed. To mitigate these issues, we demonstrate a swept-source OCTA (SS-OCTA) system by employing a swept source based on a vertical cavity surface-emitting laser...
November 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29154501/challenges-to-laser-assisted-drug-delivery-applying-theory-to-clinical-practice
#15
Omer Ibrahim, Emily Wenande, Sara Hogan, Kenneth A Arndt, Merete Haedersdal, Jeffrey S Dover
BACKGROUND: The percutaneous penetration of topically applied compounds can be enhanced using external chemical or physical sources and thus laser-assisted drug delivery is a burgeoning area of interest within the field of dermatology. OBJECTIVES: This article briefly discusses the mechanism of laser-assisted drug delivery and expands upon the challenges and safety issues that may arise in the clinical implementation of this modality. RESULTS: The existing literature demonstrates that investigators and clinicians in dermatology have successfully delivered anti-inflammatory, anti-neoplastic, and anti-oxidative medications transdermally for the treatment of a variety of conditions including scarring, photoageing, and cutaneous neoplasia...
January 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29150153/-dermatologic-surgery-hemophilia-and-von-willebrand-disease
#16
M Say, N Dupin, N Stieltjes, M-F Avril, S Aractingi, J Chanal
BACKGROUND: Von Willebrand disease (VWD) and hemophilia A and B are the most common types of hereditary coagulation-factor deficiencies. The frequency and type of complications of skin surgery in these patients are unknown. The increasing incidence of skin cancer prompted us to reflect upon this issue. While the incidence of skin cancer is increasing, the complications of skin surgery or ablative laser treatment remain unknown in this population. AIM: The aim of this study was to determine the frequency of bleeding complications during and after skin surgery in patients with a hereditary coagulation-factor deficiency (hemophilia or VWD)...
November 14, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29141057/lasers-light-and-the-treatment-of-acne-a-comprehensive-review-of-the-literature
#17
Lana X Tong, Jeremy A Brauer
INTRODUCTION: Acne vulgaris is common dermatologic condition with an estimated prevalence of 70 to 87%. Acne has been shown to have a significant impact on patient quality of life and mental health, especially as inflammatory lesions typically occur on cosmetically sensitive areas with the potential for permanent scarring. There have been numerous advances in the treatment of inflammatory acne with light-based and laser devices. OBJECTIVE: To review the current evidence for light-based and laser treatments in the management of inflammatory acne...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29139364/advanced-management-of-severe-keloids
#18
REVIEW
Thomas Hagele, Hoka Nyanda, Nishit Patel, Nicole Russell, George Cohen, Christopher Nelson
Keloids negatively impact the health and quality of life of many affected dermatologic patients. Treating keloids is often difficult, and suboptimal responses are frequent. Fortunately, there are many treatment options available to the clinician that may lead to improved clinical outcomes. We present a review of currently available therapeutic options. Intralesional steroid injection remains the first-line treatment for keloids. Imiquimod, direct interferon therapy, or intralesional 5-flurouracil may alleviate the need for excessive corticosteroid therapy...
2017: Skinmed
https://www.readbyqxmd.com/read/29089786/can-laser-treatment-improve-quality-of-life-of-hirsute-women
#19
Narges Alizadeh, Sharad Ayyoubi, Mohammadreza Naghipour, Rasool Hassanzadeh, Zahra Mohtasham-Amiri, Shirin Zaresharifi, Kaveh Gharaei Nejad
BACKGROUND: Hirsutism can have negative impacts on psychosocial aspects of women's lives and reduce their quality of life (QOL). The aim of this study was to assess the QOL of these women during laser treatment. PATIENTS AND METHODS: Eighty-eight women with unwanted facial hair underwent laser therapy. Each patient completed a questionnaire consisting of a modified Dermatology Life Quality Index (DLQI) and visual analog scale (VAS) before the first, third, and fifth sessions of laser therapy...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29064982/lasers-and-energy-based-devices-in-men
#20
REVIEW
Milène K Crispin, George J Hruza, Suzanne L Kilmer
BACKGROUND: The demand for cosmetic treatments with lasers and energy-based devices has increased among men, but there is a dearth of literature that addresses the approach and treatment of cosmetic male patients. OBJECTIVE: To summarize common cosmetic concerns for which male patients seek cosmetic treatments and to provide sex-specific recommendations for the lasers and energy-based devices that can be used for treatment. MATERIALS AND METHODS: The authors conducted a literature search using the PubMed/MEDLINE and Google Scholar databases using the search terms male, men, gender, and cosmetic dermatology...
November 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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