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https://www.readbyqxmd.com/read/29906435/the-association-of-previous-prostate-biopsy-related-complications-and-the-type-of-complication-with-patient-compliance-with-re-biopsy-scheme
#1
Logan S Schwarzman, Michael R Abern, Daniel F Garvey, Gerald L Andriole, Stephen J Freedland, Daniel M Moreira
INTRODUCTION: Prostate biopsy complications have important consequences that may affect patient compliance with re-biopsy schemes; however, this has not been studied in earnest. Thus, we evaluated whether previous prostate biopsy-related complications and the type of complication were associated with repeat prostate biopsy compliance in a clinical trial with study-mandated systematic biopsies. MATERIALS AND METHODS: Retrospective analysis of 4,939 men ages 50-75 who underwent a 2-year prostate biopsy and were recommended to undergo the 4-year prostate re-biopsy in the Reduction by Dutasteride of prostate cancer Events (REDUCE) study...
June 12, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29900824/an-implementation-of-next-generation-sequencing-for-prevention-and-diagnosis-of-urinary-tract-infection-in-urology
#2
Vladimir Mouraviev, Michael McDonald
INTRODUCTION: The changing face of current infection phenotypes from planktonic to biofilm type has been developed implicating bacterial biofilms in recurrent infection. To date, no specific medical treatment exists to specifically target biofilms in the human host. Similarly, the identification of a biofilm has relied upon the analysis of tissue samples with electron microscopy or DNA identification with polymerase chain reaction (PCR) and sequencing. Standard culture and sensitivity test is not able to detect a presence of biofilms...
June 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29896329/detection-of-antimicrobial-susceptibility-and-integrons-among-extended-spectrum-%C3%AE-lactamase-producing-uropathogenic-escherichia-coli-isolates-in-southwestern-iran
#3
Hadi Sedigh Ebrahim-Saraie, Niloofar Zahedian Nezhad, Hamid Heidari, Ashkan Motamedifar, Mohammad Motamedifar
Objectives: Urinary tract infections (UTIs) are one of the most prevalent infectious diseases and can lead to a high rate of morbidity and mortality. The emergence of multiple-drug resistant strains, particularly extended-spectrum beta-lactamases (ESBLs) producing strains, has become a global healthcare concern. Our study sought to investigate the antimicrobial resistance pattern and presence of integrons and fimH determinants among uropathogenic Escherichia coli (UPEC) isolates obtained from hospitalized Iranian patients...
May 2018: Oman Medical Journal
https://www.readbyqxmd.com/read/29892948/complete-genome-sequence-of-uropathogenic-escherichia-coli-isolate-upec-26-1
#4
Bindu Subhadra, Dong Ho Kim, Jaeseok Kim, Kyungho Woo, Kyung Mok Sohn, Hwa-Jung Kim, Kyudong Han, Man Hwan Oh, Chul Hee Choi
Urinary tract infections (UTIs) are among the most common infections in humans, predominantly caused by uropathogenic Escherichia coli (UPEC). The diverse genomes of UPEC strains mostly impede disease prevention and control measures. In this study, we comparatively analyzed the whole genome sequence of a highly virulent UPEC strain, namely UPEC 26-1, which was isolated from urine sample of a patient suffering from UTI in Korea. Whole genome analysis showed that the genome consists of one circular chromosome of 5,329,753 bp, comprising 5064 protein-coding genes, 122 RNA genes (94 tRNA, 22 rRNA and 6 ncRNA genes), and 100 pseudogenes, with an average G+C content of 50...
June 2018: Genes & Genomics
https://www.readbyqxmd.com/read/29891542/urine-cytokine-and-chemokine-levels-predict-urinary-tract-infection-severity-independent-of-uropathogen-urine-bacterial-burden-host-genetics-and-host-age
#5
Chelsie E Armbruster, Sara N Smith, Lona Mody, Harry L T Mobley
Urinary tract infections (UTIs) are among the most common infections worldwide. Diagnosing UTIs in older adults poses a significant challenge as asymptomatic colonization is common. Identification of a non-invasive profile that predicts likelihood of progressing from urine colonization to severe disease would provide a significant advantage in clinical practice. We monitored colonization susceptibility, disease severity, and immune response to two uropathogens in two mouse strains across three age groups to identify predictors of infection outcome...
June 11, 2018: Infection and Immunity
https://www.readbyqxmd.com/read/29880781/inhibition-and-inactivation-of-uropathogenic-escherichia-coli-biofilms-on-urinary-catheters-by-sodium-selenite
#6
Amoolya Narayanan, Meera S Nair, Muhammed S Muyyarikkandy, Mary Anne Amalaradjou
Urinary tract infections (UTI) are the most common hospital-acquired infections in humans and are caused primarily by uropathogenic Escherichia coli (UPEC). Indwelling urinary catheters become encrusted with UPEC biofilms that are resistant to common antibiotics, resulting in chronic infections. Therefore, it is important to control UPEC biofilms on catheters to reduce the risk for UTIs. This study investigated the efficacy of selenium for inhibiting and inactivating UPEC biofilms on urinary catheters. Urinary catheters were inoculated with UPEC and treated with 0 and 35 mM selenium at 37 °C for 5 days for the biofilm inhibition assay...
June 7, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29880703/neonatal-circumcision-and-urinary-tract-infections-in-infants-with-hydronephrosis
#7
Jonathan S Ellison, Geolani W Dy, Benjamin C Fu, Sarah K Holt, John L Gore, Paul A Merguerian
BACKGROUND: Boys with urinary tract abnormalities may derive a greater benefit from newborn circumcision for prevention of urinary tract infection (UTI) than the general population. However, the effect of newborn circumcision on UTI is not well characterized across the etiological spectrum of hydronephrosis. We hypothesized that boys with an early diagnosis of hydronephrosis who undergo newborn circumcision will have reduced rates of UTI. METHODS: The MarketScan data set, an employer-based claims database, was used to identify boys with hydronephrosis or hydronephrosis-related diagnoses within the first 30 days of life...
June 7, 2018: Pediatrics
https://www.readbyqxmd.com/read/29859045/risk-factors-and-molecular-features-of-sequence-type-st-131-extended-spectrum-%C3%AE-lactamase-producing-escherichia-coli-in-community-onset-female-genital-tract-infections
#8
Young Ah Kim, Kyungwon Lee, Jae Eun Chung
BACKGROUND: Escherichia coli (E. coli) is known to cause urinary tract infection (UTI) and meningitis in neonates, as well as existing as a commensal flora of the human gut. Extended-spectrum β-lactamase (ESBL)-producing E. coli has increased in the community with the spread of CTX-M type ESBL-producing sequence type 131 (ST131)-O25-H30Rx E. coli clone. The role of ESBL-producing E. coli in female genital tract infection has not been elucidated. The clinical and molecular features of E...
June 1, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29844230/standardisation-of-perioperative-urinary-catheter-use-to-reduce-postsurgical-urinary-tract-infection-an-interrupted-time-series-study
#9
Mahsa Sadeghi, Jerome A Leis, Claude Laflamme, Darrel Sparkes, Wendy Ditrani, Aaron Watamaniuk, Ru Taggar, Fatema Jinnah, Melisa Avaness, Mary Vearncombe, Avery B Nathens
BACKGROUND: Prevention of healthcare-associated urinary tract infection (UTI) has been the focus of a national effort, yet appropriate indications for insertion and removal of urinary catheters (UC) among surgical patients remain poorly defined. METHODS: We developed and implemented a standardised approach to perioperative UC use to reduce postsurgical UTI including standard criteria for catheter insertion, training of staff to insert UC using sterile technique and standardised removal in the operating room and surgical unit using a nurse-initiated medical directive...
May 29, 2018: BMJ Quality & Safety
https://www.readbyqxmd.com/read/29795542/epidemiology-of-healthcare-associated-infections-in-polish-intensive-care-a-multicenter-study-based-on-active-surveillance
#10
Michal Walaszek, Anna Rozanska, Malgorzata Bulanda, Jadwiga Wojkowska-Mach
AIM: The aim of this study was to evaluate the incidence of health care-associated infections (HAIs) in patients treated in Polish intensive care units (ICUs). METHODS: This retrospective analysis was based on the results of active targeted surveillance, according to the recommendation of the ECDC (European Centre of Disease Control and Prevention, HAI-Net light protocol), conducted in 2013-2015 in seven ICUs for adults located in southern Poland (observational study)...
March 1, 2018: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/29779689/prevalence-of-infections-and-antimicrobial-prescribing-in-australian-aged-care-facilities-evaluation-of-modifiable-and-nonmodifiable-determinants
#11
Bennett Noleen, Nabeel Imam, Rodney James, Caroline Chen, Ann Bull, Karin Thursky, Kirsty Buising, Leon Worth
BACKGROUND: Infections in aged care residents are associated with poor outcomes, and inappropriate antimicrobial prescribing contributes to adverse events, such as the emergence of antimicrobial resistance. The objective of this study was to identify resident- and facility-level factors associated with infection and antimicrobial prescribing in Australian aged care residents. METHODS: Using data captured by a national point-prevalence survey (the Aged Care National Antimicrobial Prescribing Survey), risk and protective factors were determined by multivariate Poisson regression...
May 17, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29775211/proanthocyanidins-will-they-effectively-restrain-conspicuous-bacterial-strains-devolving-on-urinary-tract-infection
#12
REVIEW
Venkataseshan Jagannathan, Pragasam Viswanathan
Struvite or infection stones are one of the major clinical burdens among urinary tract infection, which occur due to the interaction between microbes and urine mineral components. Numerous urinary tract infection (UTI) causing microbes regulate through biofilm formation for survival from host defense, it is often found difficult in its eradication with simple anti-microbial agents and also the chance of recurrence and resistance development is significantly high. Cranberry consumption and maintenance of urinary tract health have been supported by clinical, epidemiological, and mechanistic studies...
May 18, 2018: Journal of Basic Microbiology
https://www.readbyqxmd.com/read/29766842/continuous-low-dose-antibiotic-prophylaxis-to-prevent-urinary-tract-infection-in-adults-who-perform-clean-intermittent-self-catheterisation-the-antic-rct
#13
Robert Pickard, Thomas Chadwick, Yemi Oluboyede, Catherine Brennand, Alexander von Wilamowitz-Moellendorff, Doreen McClurg, Jennifer Wilkinson, Laura Ternent, Holly Fisher, Katherine Walton, Elaine McColl, Luke Vale, Ruth Wood, Mohamed Abdel-Fattah, Paul Hilton, Mandy Fader, Simon Harrison, James Larcombe, Paul Little, Anthony Timoney, James N'Dow, Heather Armstrong, Nicola Morris, Kerry Walker, Nikesh Thiruchelvam
BACKGROUND: People carrying out clean intermittent self-catheterisation (CISC) to empty their bladder often suffer repeated urinary tract infections (UTIs). Continuous once-daily, low-dose antibiotic treatment (antibiotic prophylaxis) is commonly advised but knowledge of its effectiveness is lacking. OBJECTIVE: To assess the benefit, harms and cost-effectiveness of antibiotic prophylaxis to prevent UTIs in people who perform CISC. DESIGN: Parallel-group, open-label, patient-randomised 12-month trial of allocated intervention with 3-monthly follow-up...
May 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29766339/predicting-factors-for-shunt-dependent-hydrocephalus-in-patients-with-aneurysmal-subarachnoid-hemorrhage
#14
Yung Ki Park, Hyeong-Joong Yi, Kyu-Sun Choi, Young-Jun Lee, Hyoung-Joon Chun, Sae Min Kwon, Dong-Won Kim
BACKGROUND: Chronic hydrocephalus after aneurysmal subarachnoid hemorrhage (SAH) is a major complication that leads to a medical burden and poor clinical outcomes. The aim of this study was to evaluate the predictive factors of shunt-dependent hydrocephalus focusing on postoperative fever and infection. METHOD: A total of 418 patients were included in this study and the patient demographic features, radiologic findings, days of fever burden, and infection were compared between the shunt (n = 72) and no shunt group (n = 346)...
May 15, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29736609/chemoprophylaxis-during-transrectal-prostate-needle-biopsy-critical-analysis-through-randomized-clinical-trial
#15
Ahmed M Elshal, Ahmed M Atwa, Ahmed R El-Nahas, Mohamed A El-Ghar, Asaad Gaber, Essam Elsawy, Abdelwahab Hashem, Yasser Farag, Hashim Farg, Ali Elsorougy, Mohamed Fouda, Hossam Nabeeh, Ahmed Mosbah
PURPOSE: To compare the efficacy of three chemoprophylaxis approaches in prevention of post-transrectal biopsy infectious complications (TBICs). METHODS: Patients were randomly assigned to receive ciprofloxacin 3 days 500 mg B.I.D 3 days starting the night prior to biopsy (standard prophylaxis), augmented prophylaxis using ciprofloxacin and single preprocedure shot of 160 mg gentamicin IM (augmented prophylaxis) and rectal swab culture-based prophylaxis (targeted prophylaxis)...
May 7, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29719874/reducing-the-rate-of-post-surgical-urinary-tract-infections-in-orthopedic-patients
#16
Amit Thakker, Natasha Briggs, Azusa Maeda, Julie Byrne, John Roderick Davey, Timothy D Jackson
Urinary tract infection (UTI) is the fourth leading cause of healthcare-associated infections, with approximately 70%-80% being attributed to the inappropriate use of indwelling catheters. In many cases, indwelling catheters are used inappropriately without any valid indication, creating potentially avoidable and significant patient distress, discomfort, pain and activity restrictions, together with substantial care burden, cost and hospitalisation. In the Division of Orthopedic Surgery at Toronto Western Hospital (TWH), we identified UTI rate reduction as a quality improvement priority...
2018: BMJ Open Quality
https://www.readbyqxmd.com/read/29716563/standardised-high-dose-versus-low-dose-cranberry-proanthocyanidin-extracts-for-the-prevention-of-recurrent-urinary-tract-infection-in-healthy-women-paccann-a-double-blind-randomised-controlled-trial-protocol
#17
Babar Asma, Leblanc Vicky, Dudonne Stephanie, Desjardins Yves, Howell Amy, Dodin Sylvie
BACKGROUND: Urinary tract infections (UTIs) are amongst the most common bacterial infections affecting women. Although antibiotics are the treatment of choice for UTI, cranberry derived products have been used for many years to prevent UTIs, with limited evidence as to their efficacy. Our objective is to assess the efficacy of a cranberry extract capsule standardized in A-type linkage proanthocyanidins (PACs) for the prevention of recurrent urinary tract infection. METHODS: We will perform a 1:1 randomized, controlled, double blind clinical trial in women aged 18 years or more who present ≥2 UTIs in 6 months or ≥ 3 UTIs in 12 months...
May 2, 2018: BMC Urology
https://www.readbyqxmd.com/read/29713464/an-observational-case-study-of-hospital-associated-infections-in-a-critical-care-unit-in-astana-kazakhstan
#18
Dmitriy Viderman, Yekaterina Khamzina, Zhannur Kaligozhin, Makhira Khudaibergenova, Agzam Zhumadilov, Byron Crape, Azliyati Azizan
Background: Hospital Associated infections (HAI) are very common in Intensive Care Units (ICU) and are usually associated with use of invasive devices in the patients. This study was conducted to determine the prevalence and etiological agents of HAI in a Surgical ICU in Kazakhstan, and to assess the impact of these infections on ICU stay and mortality. Objective: To assess the rate of device-associated infections and causative HAI etiological agents in an ICU at the National Research Center for Oncology and Transplantation (NRCOT) in Astana, Kazakhstan...
2018: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29707736/cost-effectiveness-of-antimicrobial-prophylaxis-for-children-in-the-rivur-trial
#19
Lane S Palmer, Casey A Seideman, Yair Lotan
PURPOSE: We evaluated the cost-effectiveness of antimicrobial prophylaxis to prevent recurrent UTIs in children with vesicoureteral reflux based on the RIVUR trial. MATERIALS AND METHODS: A decision tree model compared strategies of antimicrobial prophylaxis vs. placebo in children with reflux using results from the RIVUR trial. Risk reduction was 50% based on intention to treat analysis. Costs were based on Medicare reimbursement and data in literature. The model incorporated costs of medications, imaging and complications such as pyelonephritis, likelihood of surgery and loss of work...
April 30, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29705442/the-effects-of-training-and-the-use-of-cranberry-capsule-in-preventing-urinary-tract-infections-after-urostomy
#20
Zeynep Temiz, Ikbal Cavdar
PURPOSE: The study was conducted to investigate the effects of training provided by researcher and the use of cranberry capsule in preventing late term UTIs after urostomy. METHODS: The study included 60 patients who underwent ileal conduit diversion between June 2013 and November 2014. The participants were randomly divided into three groups. First group used cranberry capsule, second group received training about UTIs and the other control group. The patients were assessed for a UTI by laboratory analysis at 2, 3, and 4 months after discharge...
May 2018: Complementary Therapies in Clinical Practice
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