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Antimicrobial activity plant extract

J M Diaz Carrasco, L M Redondo, E A Redondo, J E Dominguez, A P Chacana, M E Fernandez Miyakawa
Necrotic enteritis (NE) is an important concern in poultry industry since it causes economic losses, increased mortality, reduction of bird welfare, and contamination of chicken products for human consumption. For decades, the use of in-feed antimicrobial growth promoters (AGPs) has been the main strategy to control intestinal pathogens including Clostridium perfringens (CP), the causative agent of NE. However, the use of AGPs in animal diet has been linked to the emergence and transmission of antimicrobial resistance through food-borne microorganisms, which has led to the ban of AGPs in many countries...
2016: BioMed Research International
Shanaz Ghuman, Bhekumthetho Ncube, Jeffrey F Finnie, Lyndy J McGaw, Roger M Coopoosamy, Johannes Van Staden
Medicinal plants used for wound healing and skin diseases are the key to unlocking the doors to combating problematic skin diseases as resistance of pathogens to pharmaceuticals and allopathic management continues to increase. The study aimed at investigating the antimicrobial efficacies, phenolic content, and cytotoxicity effects of 11 medicinal plant extracts commonly used for treating skin conditions and wound healing in traditional medicine within KwaZulu-Natal. Eleven plant species were separated into different plant parts (bulbs, roots, leaves) and extracted with different solvents...
2016: Frontiers in Pharmacology
Massoume Amini, Ali Deljou, Haidar Saify Nabiabad
Developmental deficiency of somatic embryos and regeneration to plantlets, especially in the case of transformation, are major problems of somatic embryo regeneration in alfalfa. One of the ways to overcome these problems is the use of natural plant regulators and nutrients in the culture medium of somatic embryos. For investigating the influence of Cuscuta campestris extract on the efficiency of plant regeneration and transformation, chimeric tissue type plasminogen activator was transferred to explants using Agrobacterium tumefaciens, and transgenic plants were recovered using medium supplemented with different concentration of the extract...
July 2016: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
Yun Ji Park, Thanislas Bastin Baskar, Sun Kyung Yeo, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi, Soon Sung Lim, Sang Un Park
BACKGROUND: Mentha plants containing over 25 species are aromatic perennial herbs. These species have been interested and widely used because of various clinical findings. Many volatile compounds facilitate environmental interactions such as protecting themselves from pathogens, parasites, and herbivores. Therefore, this study assessed comparison of volatile composition and antimicrobial activity from nine Mentha species. The composition of volatiles was investigated from the aerial parts of nine different Mentha species using gas chromatography-mass spectrometry (GC/MS)...
2016: SpringerPlus
Ramanathan Srinivasan, Kannan Rama Devi, Arunachalam Kannappan, Shunmugiah Karutha Pandian, Arumugam Veera Ravi
ETHNOPHARMACOLOGICAL RELEVANCE: Piper betle, a tropical creeper plant belongs to the family Piperaceae. The leaves of this plant have been well known for their therapeutic, religious and ceremonial value in South and Southeast Asia. It has also been reported to possess several biological activities including antimicrobial, antioxidant, antinociceptive, antidiabetic, insecticidal and gastroprotective activities and used as a common ingredient in indigenous medicines. In Indian system of ayurvedic medicine, P...
October 6, 2016: Journal of Ethnopharmacology
Bahaderjeet Singh, Prince Sharma, Arun Kumar, Pooja Chadha, Ramandeep Kaur, Amarjeet Kaur
ETHNOPHARMACOLOGICAL RELEVANCE: Tinospora cordifolia (Willd. Hook. f. & Thomson; family: Menispermaceae), has a long history of use in various traditional medicinal systems including "Ayurveda". It is reported to possess anticancer, antidiabetic, antimicrobial, antispasmodic, and antiinflammatory activities. T. cordifolia has also been well documented for production of various bioactive metabolites and their antioxidant activity, but the microorganisms associated with it have been least explored for the same properties...
October 6, 2016: Journal of Ethnopharmacology
Pradeep Bhaskar Bhat, Shruti Hegde, Vinayak Upadhya, Ganesh R Hegde, Prasanna V Habbu, Gangadhar S Mulgund
ETHNOPHARMACOLOGICAL RELEVANCE: Caesalpinia mimosoides Lam. is one of the important traditional folk medicinal plants in the treatment of skin diseases and wounds used by healers of Uttara Kannada district of Karnataka state (India). However scientific validation of documented traditional knowledge related to medicinal plants is an important path in current scenario to fulfill the increasing demand of herbal medicine. AIM OF THE STUDY: The study was carried out to evaluate the claimed uses of Caesalpinia mimosoides using antimicrobial, wound healing and antioxidant activities followed by detection of possible active bio-constituents...
October 4, 2016: Journal of Ethnopharmacology
Zhongjing Lu, Christopher R Dockery, Michael Crosby, Katherine Chavarria, Brett Patterson, Matthew Giedd
Escherichia coli O157:H7 and Staphylococcus aureus are two of the major pathogens frequently involved in foodborne outbreaks. Control of these pathogens in foods is essential to food safety. It is of great interest in the use of natural antimicrobial compounds present in edible plants to control foodborne pathogens as consumers prefer more natural "green" foods. Allyl isothiocyanate (AITC) is an antimicrobial compound naturally present in wasabi (Japanese horseradish) and several other edible plants. Although the antibacterial effects of pure AITC and wasabi extract (essential oil) against several bacteria have been reported, the antibacterial property of natural wasabi has not been well studied...
2016: Frontiers in Microbiology
Fatemeh Vafi, Roodabeh Bahramsoltani, Mohammad Abdollahi, Azadeh Manayi, Amir Hossein Abdolghaffari, Nasrin Samadi, Gholamreza Amin, Gholamreza Hassanzadeh, Hossein Jamalifar, Maryam Baeeri, Mohammad Heidari, Mahnaz Khanavi
OBJECTIVE: Burns are complicated traumatic injuries caused by several physical or chemical factors. Plants with a wide range of secondary metabolites, with valuable properties like antioxidant and anti-inflammatory activities, can be a promising source of wound healing agents. MATERIALS AND METHODS: Effects of hydromethanolic extracts of Lythrum salicaria and Hypericum scabrum, individually and in combination, were assessed in second-degree burn wounds in rats in comparison to a white oleaginous base (negative control) and silver sulfadiazine (positive control)...
September 29, 2016: Wounds: a Compendium of Clinical Research and Practice
Jhansi R Kalluri, Roberto Gonzalez-Rodriguez, Phil S Hartman, Armando Loni, Leigh T Canham, Jeffery L Coffer
Multiple new approaches to tackle multidrug resistant infections are urgently needed and under evaluation. One nanotechnology-based approach to delivering new relevant therapeutics involves silicon accumulator plants serving as a viable silicon source in green routes for the fabrication of the nanoscale drug delivery carrier porous silicon (pSi). If the selected plant leaf components contain medicinally-active species as well, then a single substance can provide not only the nanoscale high surface area drug delivery carrier, but the drug itself...
2016: PloS One
Bashir Ahmad, Farah Shireen, Shumaila Bashir, Ibrar Khan, Sadiq Azam
The current study was performed to synthesize stable, eco-friendly and bio-compatible silver nano-particles (AgNPs) of Agave americana, Mentha spicata and Mangifera indica leaves and to screen them for biological activities. The ultraviolet-visible spectroscopic analysis revealed that λ-max for AgNPs range from 350-500 nm. All AgNPs possessed polycrystalline structure as notified as intense graphical peaks in complete spectrum of 20 values ranging from 10-80° in X-ray diffraction measurements and supported by scanning electron microscopy data...
October 2016: IET Nanobiotechnology
Mohamad S Alsalhi, Sandhanasamy Devanesan, Akram A Alfuraydi, Radhakrishnan Vishnubalaji, Murugan A Munusamy, Kadarkarai Murugan, Marcello Nicoletti, Giovanni Benelli
BACKGROUND: The present study focused on a simple and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) with multipurpose anticancer and antimicrobial activities. MATERIALS AND METHODS: We studied a green synthesis route to produce AgNPs by using an aqueous extract of Pimpinella anisum seeds (3 mM). Their antimicrobial activity and cytotoxicity on human neonatal skin stromal cells (hSSCs) and colon cancer cells (HT115) were assessed. RESULTS: A biophysical characterization of the synthesized AgNPs was realized: the morphology of AgNPs was determined by transmission electron microscopy, energy dispersive spectroscopy, X-ray powder diffraction, and ultraviolet-vis absorption spectroscopy...
2016: International Journal of Nanomedicine
Dalia Seleem, Vanessa Pardi, Ramiro Mendonça Murata
Flavonoids are a subdivision of polyphenols, a versatile class of natural compounds that represent secondary metabolites from higher plants and are abundant in human diet. Various protective effects of flavonoids have been reported, including antimicrobial and antifungal activities. Due to the nature of oral candidiasis and the increased use of antifungal agents, several drug-resistant strains have emerged making it impractical to rely on one standard therapeutic regime. The aim of this review is to summarize the antifungal activity of some examples of the major subclasses of flavonoids in pure extract forms against C...
August 27, 2016: Archives of Oral Biology
Francisca Kama-Kama, Jacob Midiwo, Joseph Nganga, Naomi Maina, Elise Schiek, Leonidah Kerubo Omosa, George Osanjo, Jan Naessens
ETHNOPHARMOCOLOGICAL RELEVANCE: Members of 'Mycoplasma mycoides cluster' are important ruminant pathogens in Africa. Diseases caused by these Mycoplasma negatively affect the agricultural sector especially in developing countries through losses in livestock productivity, mortality and international trade restrictions. There is therefore urgent need to develop antimicrobials from alternative sources such as medicinal plants to curb these diseases. In Kenya, smallholder farmers belonging to the Maasai, Kuria and Luo rely on traditional Kenyan herbals to treat respiratory symptoms in ruminants...
November 4, 2016: Journal of Ethnopharmacology
Md Mamun Or Rashida, Md Shafiul Islam, Md Azizul Haque, Md Arifur Rahman, Md Tanvir Hossain, Md Abdul Hamid
Plants or natural resources have been found to be a good alternative method for nanoparticles synthesis. In this study, polyaniline coated silver nanoparticles (AgNPs) synthesized from Piper betle leaves extract were investigated for their antibacterial activity. Silver nanoparticles were prepared from the reduction of silver nitrate and NaBH4 was used as reducing agent. Silver nanoparticles and extracts were mixed thoroughly and then coated by polyaniline. Prepared nanoparticles were characterized by Visual inspection, Ultraviolet-visible spectroscopy (UV), Fourier transform infrared Spectroscopy (FT-IR), Transmission Electron Microscopy (TEM) techniques...
2016: Iranian Journal of Pharmaceutical Research: IJPR
Nighat Fatima, Usman Mukhtar, Ihsan-Ul-Haq, Muneer Ahmed Qazi, Muniba Jadoon, Safia Ahmed
BACKGROUND: The endophytes of medicinal plants, such as Justicia adhatoda L., represent a promising and largely underexplored domain that is considered as a repository of biologically active compounds. OBJECTIVES: The aim of present study was isolation, identification, and biological evaluation of endophytic fungi associated with the J. adhatoda L. plant for the production of antimicrobial, antioxidant, and cytotoxic compounds. MATERIALS AND METHODS: Endophytic fungi associated with the J...
June 2016: Jundishapur Journal of Microbiology
Laure Brigitte Kouitcheu Mabeku, Bertrand Eyoum Bille, Eveline Nguepi
This study was performed to evaluate the antimicrobial activities of extracts of Bidens pilosa, Galinsoga ciliata, and Eryngium foetidum against 6 clinical strains of Helicobacter pylori in vitro and in vivo. Broth microdilution method was used in vitro. In vivo, Swiss mice were inoculated with H. pylori and divided into 5 groups; the control group received the vehicle and the four others received 125, 250, and 500 mg/kg of methanol extract of Eryngium foetidum and ciprofloxacin (500 mg/kg) for 7 days, respectively...
2016: BioMed Research International
J Saúl García-Pérez, Sara P Cuéllar-Bermúdez, Alejandra Arévalo-Gallegos, José Rodríguez-Rodríguez, Hafiz M N Iqbal, Roberto Parra-Saldivar
Supercritical fluid extraction (SFE) is a sustainable technique used for the extraction of lipophilic metabolites such as pigments and fatty acids. Arnica plant is considered a potential candidate material with high antioxidant and antimicrobial activities. Therefore, in this study, a locally available Heterotheca inuloides, also known as Mexican arnica, was analyzed for the extraction of high-value compounds. Based on different pressure (P), temperature (T), and co-solvent (CoS), four treatments (T) were prepared...
2016: International Journal of Molecular Sciences
Prudence N Kabongo-Kayoka, Jacobus N Eloff, Chikwelu L Obi, Lyndy J McGaw
Treatment of tuberculosis (TB) is a challenge because of multidrug-resistant and extremely drug-resistant strains of Mycobacterium tuberculosis. Plant species contain antimicrobial compounds that may lead to new anti-TB drugs. Previous screening of some tree species from the Anacardiaceae family revealed the presence of antimicrobial activity, justifying further investigations. Leaf extracts of 15 Anacardiaceae tree species were screened for antimycobacterial activity using a twofold serial microdilution assay against the pathogenic Mycobacterium bovis and multidrug resistant M...
September 13, 2016: Phytotherapy Research: PTR
Mubo A Sonibare, Oluwafunmilola T Aremu, Patricia N Okorie
BACKGROUND: Vernonia cinerea (L.) Less is used in folk medicine as a remedy for various diseases. OBJECTIVES: The present study reports antioxidant and antimicrobial activities of solvent fractions of Vernonia cinerea. METHODS: The antioxidant properties of solvent fractions of V. cinerea were evaluated by determining radicals scavenging activity, total flavonoid and phenolic contents measured with the 2,2-diphenyl-1-picryl hydrazyl (DPPH) test, the aluminum chloride and the Folin-ciocalteau methods, respectively...
June 2016: African Health Sciences
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