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Antimicrobial activity plant extract

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https://www.readbyqxmd.com/read/28630440/looking-to-nature-for-a-new-concept-in-antimicrobial-treatments-isoflavonoids-from-cytisus-striatus-as-antibiotic-adjuvants-against-mrsa
#1
Ana Cristina Abreu, Aline Coqueiro, Andi R Sultan, Nicole Lemmens, Hye Kyong Kim, Robert Verpoorte, Willem J B van Wamel, Manuel Simões, Young Hae Choi
The spread of multidrug-resistant Staphylococcus aureus strains, including methicillin-resistant S. aureus (MRSA), has shortened the useful life of anti-staphylococcal drugs enormously. Two approaches can be followed to address this problem: screening various sources for new leads for antibiotics or finding ways to disable the resistance mechanisms to existing antibiotics. Plants are resistant to most microorganisms, but despite extensive efforts to identify metabolites that are responsible for this resistance, no substantial progress has been made...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28627377/mikania-glomerata-sprengel-extract-and-its-major-compound-ent-kaurenoic-acid-display-activity-against-bacteria-present-in-endodontic-infections
#2
Dora Lúcia Carrara Moreti, Luís Fernando Leandro, Thaís da Silva Moraes, Monique Rodrigues Moreira, Rodrigo Cassio Sola Veneziani, Sergio Ricardo Ambrosio, Brenda Paula Figueiredo Almeida Gomes, Carlos Henrique Gomes Martins
The search for new, effective and safe antimicrobial compounds from plant sources has continued to play an important role in the maintenance of human health since ancient times. Such compounds can be used to help to eradicate microorganisms from the root canal system, preventing/healing periapical diseases. Mikania glomerata (Spreng.), commonly known as "guaco," is a native climbing plant from Brazil that displays a wide range of pharmacological properties. Many of its activities have been attributed to its phytochemical composition, which is mainly composed of diterpenes, such as ent-kaurenoic acid (KA)...
June 13, 2017: Anaerobe
https://www.readbyqxmd.com/read/28625148/affinity-crystallography-reveals-the-bioactive-compounds-of-industrial-juicing-byproducts-of-punica-granatum-for-glycogen-phosphorylase
#3
George A Stravodimos, Anastassia L Kantsadi, Anna Apostolou, Efthimios Kyriakis, Vassiliki-Nafsika Kafaski-Kanelli, Theodora G A Solovou, Pagona Gatzona, Panagiota Cv Liggri, Stavroula Theofanous, Vyron A Gorgogietas, Apostolia Kissa, Chariklia Psachoula, Demetra S M Chatzileontiadou, Angelos Lemonakis, Anna-Maria G Psarra, Vassiliki T Skamnaki, Serkos Haroutounian, Demetres D Leonidas
BACKGROUND: Glycogen phosphorylase (GP) is a pharmaceutical target for the discovery of new antihyperglycaemic agents. Punica granatum is a well-known plant for its potent antioxidant and antimicrobial activities but so far has not been examined for antihyperglycaemic activity. OBJECTIVE: To examine the inhibitory potency of eighteen polyphenolic extracts obtained from Punica granatum fruits and industrial juicing byproducts against GP and discover their most bioactive ingredients...
June 18, 2017: Current Drug Discovery Technologies
https://www.readbyqxmd.com/read/28623383/ethnopharmacological-uses-phytochemistry-biological-activities-and-biotechnological-applications-of-eclipta-prostrata
#4
REVIEW
Ill-Min Chung, Govindasamy Rajakumar, Ji-Hee Lee, Seung-Hyun Kim, Muthu Thiruvengadam
Eclipta prostrata belongs to a family of medicinal plants (Asteraceae) and plays a role in the treatment of several diseases, including infectious hepatitis, snake venom poisoning, gastritis, and respiratory diseases such as a cough and asthma. A number of compounds, including thiophene derivatives, steroids, triterpenes, flavonoids, polyacetylenes, polypeptides, and coumestans, have been isolated from E. prostrata. The plant functional compounds can act as reducing agent in the field of nanoparticle synthesis...
June 16, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28622602/assessment-of-the-phenolic-profile-antimicrobial-activity-and-oxidative-stability-of-transgenic-perilla-frutescens-l-overexpressing-tocopherol-methyltransferase-%C3%AE-tmt-gene
#5
Bimal Kumar Ghimire, Chang Yeon Yu, Ill-Min Chung
This study evaluated the effects of enhanced concentrations of α-tocopherol and phenolic compounds on the resistance and stability of Perilla oil in transgenic Perilla frutescens plants against various tested pathogenic bacteria by over-expressing the γ-tmt gene. The concentration of phenolic compounds in the non-transgenic samples was 9313.198 ± 18.887 μg g(-1) dry weight (DW), whereas the total concentration of the transgenic samples ranged from 9118.015 ± 18.822 to 10527.612 ± 20.411 μg g(-1) DW...
June 7, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28619636/isolation-and-characterization-of-a-non-specific-lipid-transfer-protein-from-chelidonium-majus-l-latex
#6
Robert Nawrot, Damian Jozefiak, Anna Sip, Dorota Kuzma, Oskar Musidlak, Anna Gozdzicka-Jozefiak, Jakub Barylski
Plant non-specific lipid transfer proteins (nsLTPs) are small basic proteins, which mostly play a role in intracellular lipid transport and antimicrobial defense. Recently it was shown using shotgun proteomic approach that the whole plant extract of Chelidonium majus L. (Papaveraceae) contains relatively abundant nsLTPs. Therefore the aim of the work was to isolate and characterize nsLTP from C. majus latex. RESULTS: obtained using PCR approach with degenerate primers showed nsLTP protein from C...
June 12, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28606081/isolation-of-anti-mycobacterial-compounds-from-curtisia-dentata-burm-f-c-a-sm-curtisiaceae
#7
Victor O Fadipe, Nkoana I Mongalo, Andy R Opoku, Preachers M Dikhoba, Tshepiso J Makhafola
BACKGROUND: Tuberculosis is counted amongst the most infectious and lethal illnesses worldwide and remains one of the major threats to human health. The aim of the current study was to isolate and characterize anti-mycobacterial compounds present in Curtisia dentata (Burm.f.) C.A.Sm , a medicinal plant reportedly used in the treatment of tuberculosis, stomach ailments and sexually transmitted infections. METHODS: The bioassay guided principle was followed to isolate the anti-mycobacterial compounds...
June 12, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28604361/synthetic-scaffolds-with-full-pore-interconnectivity-for-bone-regeneration-prepared-by-supercritical-foaming-using-advanced-biofunctional-plasticizers
#8
Aurelio Salerno, Sara Diéguez, Luis Diaz-Gomez, Jose Luis Gomez-Amoza, Beatriz Magariños, Angel Concheiro, Concepcion Domingo, Carmen Alvarez-Lorenzo, Carlos A García-González
Supercritical foaming allows for the solvent-free processing of synthetic scaffolds for bone regeneration. However, the control on the pore interconnectivity and throat pore size with this technique still needs to be improved. The use of plasticizers may help to overcome these limitations. Eugenol, a GRAS natural compound extracted from plants, is proposed in this work as an advanced plasticizer with bioactive properties. Eugenol-containing poly(ɛ-caprolactone) (PCL) scaffolds were obtained by supercritical foaming (20...
June 12, 2017: Biofabrication
https://www.readbyqxmd.com/read/28603575/antimicrobial-fungal-endophytes-from-the-botanical-medicine-goldenseal-hydrastis-canadensis
#9
Joseph M Egan, Amninder Kaur, Huzefa A Raja, Joshua J Kellogg, Nicholas H Oberlies, Nadja B Cech
The potential of fungal endophytes to alter or contribute to plant chemistry and biology has been the topic of a great deal of recent interest. For plants that are used medicinally, it has been proposed that endophytes might play an important role in biological activity. With this study, we sought to identify antimicrobial fungal endophytes from the medicinal plant goldenseal (Hydrastis canadensis L., Ranunculaceae), a plant used in traditional medicine to treat infection. A total of 23 fungal cultures were obtained from surface-sterilized samples of H...
September 2016: Phytochemistry Letters
https://www.readbyqxmd.com/read/28597160/purification-and-characterization-of-a-newly-serine-protease-inhibitor-from-rhamnus-frangula-with-potential-for-use-as-therapeutic-drug
#10
Abir Ben Bacha, Ikram Jemel, Nadine M S Moubayed, Imen Ben Abdelmalek
Protease inhibitors from plants are well known to be potent inhibitors of the growth of bacteria, fungi, and even certain viruses which make them excellent candidates for use as the lead compounds for the development of novel antimicrobial agents for applications in medicine. In this study, Rhamnus frangula was selected as a protease inhibitor source. The maximum recovery of the protease inhibitor against trypsin was recorded in the crude extract made in 0.1 M phosphate buffer (pH 7.0) and isolated from the mature leaves...
June 2017: 3 Biotech
https://www.readbyqxmd.com/read/28595608/antimicrobial-activity-toxicity-and-anti-inflammatory-potential-of-methanolic-extracts-of-four-ethnomedicinal-plant-species-from-punjab-pakistan
#11
Rabia Naz, Hafsa Ayub, Sajid Nawaz, Zia Ul Islam, Tayyaba Yasmin, Asghari Bano, Abdul Wakeel, Saqib Zia, Thomas H Roberts
BACKGROUND: The plant species Aristolochia indica (AI), Melilotus indicus (MI), Tribulus terrestris (TT) and Cuscuta pedicellata (CP) are widely used in folk medicine in the villages around Chowk Azam, South Punjab, Pakistan. The aim of this study was to evaluate the antioxidant activity, phytochemical composition, and the antibacterial, antifungal, cytotoxic and anti-inflammatory potential of the four medicinal plants listed above. For CP stem, this study represents (to the best of our knowledge) the first time phytochemicals have been identified and the antioxidant and anti-inflammatory potential determined...
June 8, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28593176/radix-bupleuri-a-review-of-traditional-uses-botany-phytochemistry-pharmacology-and-toxicology
#12
REVIEW
Fude Yang, Xiaoxv Dong, Xingbin Yin, Wenping Wang, Longtai You, Jian Ni
Radix Bupleuri (Chaihu) has been used as a traditional medicine for more than 2000 years in China, Japan, Korea, and other Asian countries. Phytochemical studies demonstrated that this plant contains essential oils, triterpenoid saponins, polyacetylenes, flavonoids, lignans, fatty acids, and sterols. Crude extracts and pure compounds isolated from Radix Bupleuri exhibited various biological activities, such as anti-inflammatory, anticancer, antipyretic, antimicrobial, antiviral, hepatoprotective, neuroprotective, and immunomodulatory effects...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28584446/antimicrobial-activity-of-various-ethanolic-plant-extracts-against-pathogenic-multi-drug-resistant-candida-spp
#13
Shaista Khan, Mohd Imran, Mohammed Imran, Nuzhat Pindari
A total of 50 Candida isolates were isolated and identified from clinical specimens and these were tested for resistance to various antifungal drugs. It was observed multi-drug resistance in all candida isolates by 84%, 62%, 60%, 76%, 46, 30%, and 22% against fluconazole, clotrimazole, Amphotericin B, itraconazole, ketoconazole, miconazole and nystatin tested respectively. The isolates, which were found to be resistant to antifungal drugs were selected and subjected to antifungal testing against six ethanolic plants, extract namely Azadiracta indica, Allium sativum, Cordia dichotoma Ocimum sanctum, Syzygium cumini and Trigonella foenum grecum...
2017: Bioinformation
https://www.readbyqxmd.com/read/28583887/antimicrobial-activity-of-plant-median-synthesized-silver-nanoparticles-against-food-and-agricultural-pathogens
#14
Foysal Kabir Tareq, Mst Fayzunnesa, Md Shahariar Kabir
The adjuvant applications of silver nanoparticles (AgNPs) in food and agro-ecosystems are not completely pursued, which most of the researchers confined to laboratory inventions. AgNPs is gaining a lot of interest among worldwide researcher due to exhibit antimicrobial properties and unique physiochemical properties. In addition, the facile and economically friendly method called biological method to synthesis of AgNPs using Bryophyllum pinnatum leaf extract over other methods and including antimicrobial properties, there is no doubt that AgNPs could be twirled the food and agricultural sector in future...
June 3, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28583316/formulation-development-and-evaluation-of-antimicrobial-polyherbal-gel
#15
S D Bhinge, M A Bhutkar, D S Randive, G H Wadkar, S S Todkar, P M Kakade, P M Kadam
OBJECTIVE: In the recent years, there has been a gradual revival of interest in the use of medicinal plants in developing countries because herbal medicines have been reported safe with minimal adverse side effect especially when compared with synthetic drugs. METHOD: In the present study we prepared gel formulations (formulations A and B) which comprised of ethanolic extract of Azadirachta indica, Curcuma longa, Allium sativum, Ocimum sactum, Cinnamomum zeylanicum nees and Tamarindus indica in a concentration of 0...
June 2, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28583179/comparison-between-the-effects-of-potassium-phosphite-and-chitosan-on-changes-in-the-concentration-of-cucurbitacin-e-and-on-antibacterial-property-of-cucumis-sativus
#16
Moazzameh Ramezani, Fatemeh Rahmani, Ali Dehestani
BACKGROUND: Cucurbitacins are mostly found in the members of the family Cucurbitaceae and are responsible for the bitter taste of cucumber. Pharmacological activities such as anti-bacterial and anti-tumor effects have been attributed to these structurally divers triterpens. The aim of this study was to investigate the effect of potassium phosphite (KPhi) and chitosan on Cucurbitacin E (CuE) concentration in different tissues of Cucumis sativus. The antibacterial effect of plant ethanolic extracts was also examined against E...
June 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28575946/microwave-assisted-extraction-as-an-efficient-approach-for-biosynthesis-of-zinc-oxide-nanoparticles-synthesis-characterization-and-biological-properties
#17
Hamid Reza Rajabi, Reza Naghiha, Mansoureh Kheirizadeh, Hamed Sadatfaraji, Ali Mirzaei, Zinab Moradi Alvand
In the present study, microwave assisted extraction (MAE) was applied as an efficient, green and rapid approach to prepare the aqueous extract of Suaeda aegyptiaca (SA) plant. The obtained aqueous extracts at two different irradiation power (90 and 270W; 15min) in MAE process as well as maceration method (24h) were used in a green and eco-friendly approach for the synthesis of zinc oxide nanoparticles (ZnO NPs). The synthesized ZnO NPs have been characterized via different techniques including UV-Vis absorption; fluorescence and Fourier transform infrared (FT-IR) spectroscopices, scanning electron microscopy (SEM), and X-ray diffraction (XRD)...
September 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28573243/in-vitro-efficacy-of-extracts-from-plants-used-by-small-holder-farmers-in-the-treatment-of-dermatophilosis-in-cattle
#18
Daud N Ndhlovu, Patrick J Masika
BACKGROUND: Bovine dermatophilosis, an important skin disease of cattle caused by Dermatophilus congolensis, negatively impacts the livelihoods of small-holder farmers in Zimbabwe. This impact is through, morbidity, loss of draught animal power, costs incurred to manage the disease, losses associated with devalued damaged hides and the resultant culling of some of the affected cattle. Due to the inaccessibility of conventional drugs to manage bovine dermatophilosis, farmers have been reported to use local medicinal plants to manage the disease...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28573239/therapeutic-potentials-of-ethanolic-extract-of-leaves-of-holarrhena-floribunda-g-don-dur-and-schinz-apocynaceae
#19
Yao Patrick Hoekou, Tchadjobo Tchacondo, Simplice Damintoti Karou, Rakiswende Serge Yerbanga, Elom Achoribo, Ollo Da, Wouyo Atakpama, Komlan Batawila
BACKGROUND: Holarrhena floribunda is a plant of wide usage in the Togolese folk medicine. A previous ethnobotanical survey on the latex plants of the Maritime region of the country revealed that this plant was included in several recipes curing malaria and microbial infections. Therefore, this study aimed to seek for the effectiveness of the ethanolic extract of the plant in the treatment of these diseases. METHODS: The antimicrobial test was performed using the agar well-diffusion and the NCCLS broth microdilution methods, while the in vivo antimalarial activity was evaluated following the four-day suppressive test of Peters...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28573232/antimicrobial-activities-of-some-saudi-arabian-herbal-plants
#20
Abdelaaty A Shahat, Elsayed A Mahmoud, Abdullah A Al-Mishari, Mansour S Alsaid
BACKGROUND: Several edible plants are used in Kingdom of Saudi Arabia since early time to control microbial infections. In the present study, twenty-four Saudi Arabian medicinal plants d according to traditionally used were select and investigated for the antimicrobial activities. MATERIALS AND METHODS: This study was designed at evaluating the antimicrobial activities of the methanol extracts of twenty-four species of sixteen plant families used in the traditional medicine by Saudi Arabian people for the treatment of numerous ailments of the microbial and non-microbial origin against four Gram-positive, four Gram-negative bacteria and four fungi and yeast using the agar well diffusion method...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
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