keyword
MENU ▼
Read by QxMD icon Read
search

Gap detection

keyword
https://www.readbyqxmd.com/read/28917618/gap-balancing-sacrifices-joint-line-maintenance-to-improve-gap-symmetry-5-year-follow-up-of-a-randomized-controlled-trial
#1
Sina Babazadeh, Michelle M Dowsey, Michael G Vasimalla, James D Stoney, Peter F M Choong
BACKGROUND: Gap balancing (GB) has been noted to sacrifice joint-line maintenance to improve gap symmetry. This study aims to determine whether this change affects function or quality of life in the midterm. METHODS: A prospective blinded randomized controlled trial was completed with 103 patients randomized to measured resection (n = 52) or GB (n = 51). Primary outcome measured was femoral component rotation. Secondary outcomes measured were joint-line change, gap symmetry, and function and quality-of-life outcomes...
August 24, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28915657/the-prevalence-subtypes-and-associated-factors-of-hyperuricemia-in-lupus-nephritis-patients-at-chronic-kidney-disease-stages-1-3
#2
Simeng Liu, Yijun Gong, Hong Ren, Wen Zhang, Xiaonong Chen, Tong Zhou, Xiao Li, Nan Chen
There is a high prevalence of hyperuricemia (HUA) in the chronic kidney disease (CKD) population. However, there's a dearth of research on HUA's prevalence, subtypes, early detection, and treatment strategies of HUA in lupus nephritis (LN) patients. The aim of this study is to address these knowledge gaps. LN patients presenting to the Department of Nephrology at Shanghai Rui Jin Hospital from January 2011 to January 2016 were recruited. The effective sample size was derived using the power analysis. The demographic, clinical and laboratory characteristics of the LN patients with HUA were compared with those of patients without HUA...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28915056/gigahertz-optomechanical-modulation-by-split-ring-resonator-nanophotonic-meta-atom-arrays
#3
Yuta Imade, Ronald Ulbricht, Motonobu Tomoda, Osamu Matsuda, Gediminas Seniutinas, Saulius Juodkazis, Oliver B Wright
Using polarization-resolved transient reflection spectroscopy, we investigate the ultrafast modulation of light interacting with a metasurface consisting of coherently vibrating nanophotonic meta-atoms in the form of U-shaped split-ring resonators, that exhibit co-localized optical and mechanical resonances. With a two-dimensional square-lattice array of these resonators formed of gold on a glass substrate, we monitor the visible-pump-pulse induced gigahertz oscillations in intensity of reflected linearly-polarized infrared probe light pulses, modulated by the resonators effectively acting as miniature tuning forks...
September 15, 2017: Nano Letters
https://www.readbyqxmd.com/read/28914955/alcohol-related-mortality-in-patients-with-psoriasis-a-population-based-cohort-study
#4
Rosa Parisi, Roger T Webb, Matthew J Carr, Kieran J Moriarty, C Elise Kleyn, Christopher E M Griffiths, Darren M Ashcroft
Importance: People diagnosed with psoriasis have an increased risk of premature mortality, but the underlying reasons for this mortality gap are unclear. Objective: To investigate whether patients with psoriasis have an elevated risk of alcohol-related mortality. Design, Setting, and Participants: An incident cohort of patients with psoriasis aged 18 years and older was delineated for 1998 through 2014 using the Clinical Practice Research Datalink (CPRD) and linked to Hospital Episode Statistics (HES) and Office for National Statistics (ONS) mortality records...
September 15, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28914654/accuracy-of-tests-used-to-detect-infection-with-chlamydia-trachomatis-in-asymptomatic-pregnant-women-a-systematic-review
#5
Siew-Veena Sahi, Ewelina Rogozińska, Soha Sobhy, Khalid S Khan
PURPOSE OF REVIEW: Infection with Chlamydia trachomatis in pregnancy is linked to increased risk of miscarriage, stillbirth, and preterm birth. Currently, PCR or DNA-based tests are the gold standard when detecting the infection; however, they are costly and require access to specialist equipment. The aim of this systematic review was to assess the accuracy of available tests to detect infection in an asymptomatic pregnant population. RECENT FINDINGS: There was evidence of the superior accuracy of nucleic acid amplification tests to cell culture in nonpregnant asymptomatic women; however, there are multiple commercial nucleic acid amplification tests with varying sensitivities and specificities...
September 12, 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28913938/application-of-craft-complete-reduction-to-amplitude-frequency-table-in-non-uniformly-sampled-nus-two-dimensional-nmr-data-processing
#6
Krish Krishnamurthy, Natarajan Hari
The recently published CRAFT (Complete Reduction to Amplitude Frequency Table) technique converts the raw FID data (i.e., time domain data) into a table of frequencies, amplitudes, decay rate constants and phases. It offers an alternate approach to decimate time-domain data, with minimal pre-processing step. It has been shown that application of CRAFT technique to process the t1 dimension of the 2D data, significantly improved the detectable resolution by it ability to analyze without the use of ubiquitous apodization of extensively zero-filled data...
September 15, 2017: Magnetic Resonance in Chemistry: MRC
https://www.readbyqxmd.com/read/28912799/triportheus-albus-cope-1872-in-the-blackwater-clearwater-and-whitewater-of-the-amazon-a-case-of-phenotypic-plasticity
#7
José D A Araújo, Andrea Ghelfi, Adalberto L Val
The Amazon basin includes 1000s of bodies of water, that are sorted according to their color in three types: blackwater, clearwater, and whitewater, which significantly differ in terms of their physicochemical parameters. More than 3,000 species of fish live in the rivers of the Amazon, among them, the sardine, Triportheus albus, which is one of the few species that inhabit all three types of water. The purpose of our study was to analyze if the gene expression of T. albus is determined by the different types of water, that is, if the species presents phenotypic plasticity to live in blackwater, clearwater, and whitewater...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/28912459/iron-deposition-is-associated-with-differential-macrophage-infiltration-and-therapeutic-response-to-iron-chelation-in-prostate-cancer
#8
Avigdor Leftin, Huiyong Zhao, Mesru Turkekul, Elisa de Stanchina, Katia Manova, Jason A Koutcher
Immune cells such as macrophages are drivers and biomarkers of most cancers. Scoring macrophage infiltration in tumor tissue provides a prognostic assessment that is correlated with disease outcome and therapeutic response, but generally requires invasive biopsy. Routine detection of hemosiderin iron aggregates in macrophages in other settings histologically and in vivo by MRI suggests that similar assessments in cancer can bridge a gap in our ability to assess tumor macrophage infiltration. Quantitative histological and in vivo MRI assessments of non-heme cellular iron revealed that preclinical prostate tumor models could be differentiated according to hemosiderin iron accumulation-both in tumors and systemically...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28912341/the-role-of-blm-helicase-in-homologous-recombination-gene-conversion-tract-length-and-recombination-between-diverged-sequences-in-drosophila
#9
Henry A Ertl, Daniel P Russo, Noori Srivastava, Joseph T Brooks, Thu N Dao, Jeannine R LaRocque
DNA double-strand breaks (DSBs) are a particularly deleterious class of DNA damage that threatens genome integrity. DSBs are repaired by three pathways: non-homologous end joining (NHEJ), homologous recombination (HR), and single-strand annealing (SSA). Drosophila melanogaster Blm (DmBlm) is the ortholog of Saccharomyces cerevisiae SGS1 and human BLM, and has been shown to suppress crossovers in mitotic cells and repair mitotic DNA gaps via HR. To further elucidate the role of DmBlm in repair of a simple DSB, and in particular recombination mechanisms, we utilized the DR-white and DR-white...
September 14, 2017: Genetics
https://www.readbyqxmd.com/read/28911821/on-the-occurrence-and-enigmatic-functions-of-mixed-chemical-plus-electrical-synapses-in-the-mammalian-cns
#10
REVIEW
James I Nagy, Alberto E Pereda, John E Rash
Electrical synapses with diverse configurations and functions occur at a variety of interneuronal appositions, thereby significantly expanding the physiological complexity of neuronal circuitry over that provided solely by chemical synapses. Gap junctions between apposed dendritic and somatic plasma membranes form "purely electrical" synapses that allow for electrical communication between coupled neurons. In addition, gap junctions at axon terminals synapsing on dendrites and somata allow for "mixed" (dual chemical+electrical) synaptic transmission...
September 11, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28910394/up-regulation-of-gap-junction-in-peripheral-blood-t-lymphocytes-contributes-to-the-inflammatory-response-in-essential-hypertension
#11
Xin Ni, Ai Wang, Liang Zhang, Li-Ya Shan, Hai-Chao Zhang, Li Li, Jun-Qiang Si, Jian Luo, Xin-Zhi Li, Ke-Tao Ma
Inflammation has been shown to play an important role in the mechanisms involved in the pathogenesis of hypertension. Connexins (Cxs)-based gap junction channels (GJCs) or hemichannels (HCs) are involved in the maintenance of homeostasis in the immune system. However, the role of Cx43-based channels in T-lymphocytes in mediating the immune response in essential hypertension is not fully understand. The present study was designed to investigate the role of Cxs-based channels in T lymphocytes in the regulation of hypertension-mediated inflammation...
2017: PloS One
https://www.readbyqxmd.com/read/28906204/context-is-everything-from-cardiovascular-disease-to-cerebral-microbleeds
#12
Andreas Charidimou, Deborah Blacker, Anand Viswanathan
Increasingly, our approach to cerebrovascular disease has become blurred by evidence published in literature often without careful consideration of what this evidence implies for specific patients at hand. In this essay, we analyze key contextual issues in cerebrovascular small vessel disease, in an attempt to highlight the symbolic gap that exists between research and clinical practice, a recurring theme in medicine. We highlight the importance of considering context when using data from epidemiologic, neuroimaging, and biomarker studies in determining relevance to the patient at hand...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28901688/poly-glycerol-sebacate-combined-with-chondroitinase-abc-promotes-spinal-cord-repair-in-rats
#13
Qi Pan, Yan Guo, Fanyong Kong
This study was to investigate the feasibility of PGS combined with ChABC for repairing the transection of spinal cords (TSC) in rats. A thoracic 10 (T10) TSC model of rats was employed. The effects of PGS with ChABC on the morphology and histological structure of the spinal cords, Basso, Beattie, Bresnahan (BBB) scores, and the expression of GAP-43 and NF-200 were comparatively studied. The BBB scores indicated that all rats with TSC were paralyzed immediately after surgery and then recovered hind limb movement gradually, but did not fully recover until the end of week 12...
September 13, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28901477/simultaneous-multi%C3%A2-gene-mutation-screening-using-snpscan-in-patients-from-ethnic-minorities-with-nonsyndromic-hearing%C3%A2-impairment-in-northwest-china
#14
Shi-Hong Duan, Jian-Li Ma, Xiao-Long Yang, Yu-Fen Guo
The present study aimed to investigate the molecular etiology of nonsyndromic hearing impairment (HI) in hearing impaired populations of Hui, Tibetan, and Tu ethnicities in northwest China. A total of 283 unrelated subjects with HI who attended special education schools in northwest China were enrolled in the present study. Single-nucleotide polymorphisms (SNPs) in three common deafness‑related genes, gap junction protein β2 (GJB2), solute carrier family 26 member 4 (SLC26A4) and mitochondrially encoded 12S RNA (mtDNA12SrRNA), were detected using a SNPscan technique...
September 7, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28900455/diverse-pattern-of-gap-junction-beta-2-and-gap-junction-beta-4-genes-mutations-and-lack-of-contribution-of-dfnb21-dfnb24-dfnb29-and-dfnb42-loci-in-autosomal-recessive-nonsyndromic-hearing-loss-patients-in-hormozgan-iran
#15
Masoud Akbarzadeh Laleh, Marzieh Naseri, Ali Akbar Poursadegh Zonouzi, Ahmad Poursadegh Zonouzi, Marjan Masoudi, Najmeh Ahangari, Leila Shams, Azim Nejatizadeh
BACKGROUND: We aimed to determine the contribution of four DFNB loci and mutation analysis of gap junction beta-2 (GJB2) and GJB4 genes in autosomal recessive nonsyndromic hearing loss (ARNSHL) in South of Iran. MATERIALS AND METHODS: A total of 36 large ARNSHL pedigrees with at least two affected subjects were enrolled in the current study. The GJB2 and GJB4 genes mutations were screened using direct sequencing method. The GJB2 and GJB4 negative families were analyzed for the linkage to DFNB21, DFNB24, DFNB29, and DFNB42 loci by genotyping the corresponding STR markers using polymerase chain reaction-PAGE method...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28898544/direct-preparation-of-a-graphene-oxide-modified-monolith-in-a-glass-syringe-as-a-solid-phase-extraction-cartridge-for-the-extraction-of-quaternary-ammonium-alkaloids-from-chinese-patent-medicine
#16
Xiaojing Liang, Licheng Wang, Shuai Wang, Yijing Li, Yong Guo
Packed cartridges have been widely used in solid-phase extraction. However, there are still some drawbacks, such as they are blocked easily and the method is time-consuming. In view of the advantages of monoliths, a monolithic extraction material has been directly synthesized in a glass syringe without any gap between the monolith and syringe's inner wall. The monolithic syringe was modified with graphene oxide by loading a graphene oxide dispersion onto it. The content of graphene oxide and the surface topography of the monolith have been evaluated by elemental analysis and scanning electron microscopy, respectively, which confirmed the successful modification...
September 12, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28894894/advanced-microbial-analysis-for-wastewater-quality-monitoring-metagenomics-trend
#17
REVIEW
Jose Antonio Garrido-Cardenas, María Inmaculada Polo-López, Isabel Oller-Alberola
Urban Wastewater treatment plants (UWWTPs) have played an important and fundamental role in society for water purification of contaminated human wastewaters over the last decades. Microorganisms are very important in UWWTP as their metabolic activity significantly reduces the organic load of the UWW, although there is an uncertain gap in our knowledge regarding microbial consortium structure and their activity in UWWTP operation on a large scale. On the other hand, effluents of UWWTPs have come to be a new source of fresh water to ease water scarcity in many regions of the world, especially in intensive irrigation practices...
September 11, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28894816/evaluation-of-peripheral-nerve-regeneration-through-biomaterial-conduits-via-micro-ct-imaging
#18
Sarah K Pixley, Tracy M Hopkins, Kevin J Little, David B Hom
OBJECTIVE: Hollow nerve conduits made of natural or synthetic biomaterials are used clinically to aid regeneration of peripheral nerves damaged by trauma or disease. To support healing, conduit lumen patency must be maintained until recovery occurs. New methods to study conduit structural integrity would provide an important means to optimize conduits in preclinical studies. We explored a novel combined technique to examine structural integrity of two types of nerve conduits after in vivo healing...
December 2016: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/28894747/mirna-expression-profile-and-effect-of-wenxin-granule-in-rats-with-ligation-induced-myocardial-infarction
#19
Aiming Wu, Lixia Lou, Jianying Zhai, Dongmei Zhang, Limin Chai, Bo Nie, Haiyan Zhu, Yonghong Gao, Hongcai Shang, Mingjing Zhao
Wenxin Granule (WXKL) is a traditional Chinese medicine used for treatment of myocardial infarction (MI) and arrhythmias. However, the genomic pathological mechanisms of MI and mechanisms of WXKL are largely unknown. This study aims to investigate a comprehensive miRNA expression profile, and the predicted correlation pathways to be targeted by differentially expressed miRNAs in MI, and mechanisms of WXKL from a gene level. MI rat model was established by a coronary artery ligation surgery. miRNA expression microarrays were performed and the data were deposited in Gene Expression Omnibus (GEO number GSE95855)...
2017: International Journal of Genomics
https://www.readbyqxmd.com/read/28891447/potential-role-of-neuroimaging-markers-for-early-diagnosis-of-dementia-in-primary-care
#20
Stefan Teipel, Ingo Kilimann, Jochen R Thyrian, Stefan Klöppel, Wolfgang Hoffmann
BACKGROUND: The use of imaging markers for the diagnosis of predementia and early dementia stages of Alzheimer's disease (AD) has widely been explored in research settings and specialized care. The use of these markers in primary care has yet to be established. OBJECTIVE: Summarize current evidence for the usefulness of imaging markers for AD in primary compared to specialized care settings. METHOD: Selective overview of the literature, and pilot data on the use of MRI-based hippocampus and basal forebrain volumetry for the discrimination of AD dementia and mild cognitive impairment (MCI) cases from healthy controls in 58 cases from a primary care cohort and 58 matched cases from a memory clinic's sample...
September 7, 2017: Current Alzheimer Research
keyword
keyword
5288
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"