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https://www.readbyqxmd.com/read/29140321/single-silicon-ccd-cmos-platform-for-multi-spectral-detection-from-terahertz-to-x-rays
#1
Mostafa Shalaby, Carlo Vicario, Christoph P Hauri
Charge-coupled devices (CCDs) are a well-established imaging technology in the visible and x-ray frequency ranges. However, the small quantum photon energies of terahertz radiation have hindered the use of this mature semiconductor technological platform in this frequency range, leaving terahertz imaging totally dependent on low-resolution bolometer technologies. Recently, it has been shown that silicon CCDs can detect terahertz photons at a high field, but the detection sensitivity is limited. Here we show that silicon, complementary metal-oxide-semiconductor (CMOS) technology offers enhanced detection sensitivity of almost two orders of magnitude, compared to CCDs...
November 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29140072/novel-aerosol-phase-extraction-method-for-the-determination-of-ca-k-mg-and-na-in-biodiesel-through-inductively-coupled-plasma-atomic-emission-spectrometry
#2
Raquel Sanchez, Salvador Maestre, Maria Soledad Prats Moya, José Luis Todoli
A novel extraction method was developed, optimized and validated for the elemental analysis of organic samples. The method, called aerosol phase extraction (APE), was based on the nebulization of the extracting aqueous solution (0.1 mol L-1 nitric acid) on the sample. The extraction was performed at the interface of each generated extractant droplets as they entered in contact with the samples. Afterwards, the phases were allowed to separate and Ca, K, Na and Mg were determined in aqueous phase by means of inductively coupled plasma optical emission spectroscopy (ICP-OES)...
November 15, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29139195/phenotypic-characteristics-associated-with-slow-gait-speed-in-idiopathic-pulmonary-fibrosis
#3
Claire M Nolan, Matthew Maddocks, Toby M Maher, Jane L Canavan, Sarah E Jones, Ruth E Barker, Suhani Patel, Joseph Jacob, Paul Cullinan, William D-C Man
BACKGROUND AND OBJECTIVE: Usual gait speed over 4 m (4MGS) is an established functional performance measure in older adults that consistently predicts adverse health outcomes, but few data exist in idiopathic pulmonary fibrosis (IPF). We assessed the reliability of 4MGS, its relationship with established outcome measures and its responsiveness to pulmonary rehabilitation. METHODS: In four prospective IPF cohorts, 4MGS inter-observer (n = 46) and test-retest (n = 46) reliability, concurrent validity (n = 65 and n = 62) and responsiveness (n = 60) were determined...
November 14, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29138751/expression-of-microrna-29a-regulated-by-yes-associated-protein-modulates-the-neurite-outgrowth-in-n2a-cells
#4
Chunye Tan, Changlin Yu, Zhiwen Song, Hongjun Zou, Xu Xu, Jinbo Liu
Yes-associated protein (YAP) is proved to increase miR-29a in the present study, but the relevant molecular mechanism is not clear. Also, growing evidence indicates that the high-level miR-29a promotes the neurite outgrowth by decreasing PTEN (phosphatase and tensin homologue deleted on chromosome 10). Results show that the expression of miR-29a increases but the PTEN decreases during transfecting the N2a cells with the YAP plasmid. Meanwhile, the advancement of neurite outgrowth is presented via using multiple methods to detect the expression of GAP-43 and NF-200, which have a strong association with neurite outgrowth...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29137612/comparison-of-semi-quantitative-and-quantitative-dynamic-contrast-enhanced-mri-evaluations-of-vertebral-marrow-perfusion-in-a-rat-osteoporosis-model
#5
Jingqi Zhu, Zuogang Xiong, Jiulong Zhang, Yuyou Qiu, Ting Hua, Guangyu Tang
BACKGROUND: This study aims to investigate the technical feasibility of semi-quantitative and quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the assessment of longitudinal changes of marrow perfusion in a rat osteoporosis model, using bone mineral density (BMD) measured by micro-computed tomography (micro-CT) and histopathology as the gold standards. METHODS: Fifty rats were randomly assigned to the control group (n=25) and ovariectomy (OVX) group whose bilateral ovaries were excised (n=25)...
November 14, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29134742/innovative-technologies-for-point-of-care-testing-of-viral-hepatitis%C3%A2-in-low-resource-and-decentralized-settings
#6
Léa Duchesne, Karine Lacombe
According to the Global Burden of Diseases, chronic viral hepatitis B and C are one of the most challenging global health conditions that rank among the first causes of morbidity and mortality worldwide. Low and middle income countries are particularly affected by the health burden associated with HBV or HCV infection. One major gap in efficiently addressing the issue of viral hepatitis is universal screening. However, the costs and chronic lack of human resources for using traditional screening strategies based on serology and molecular biology preclude any scaling-up...
November 13, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29134592/identification-of-dna-base-modifications-by-means-of-pacific-biosciences-rs-sequencing-technology
#7
Philip Kelleher, James Murphy, Jennifer Mahony, Douwe van Sinderen
Whole phage genomes can be sequenced readily using one or a combination of next generation sequencing (NGS) technologies. One of the most recently developed NGS platforms, the so-called Single-Molecule Real-Time (SMRT) sequencing approach provided by the PacBio RS platform, is particularly useful in providing complete (i.e., un-gapped) genome sequences, but differs from other technologies in that the platform also allows for downstream analysis to identify nucleotides that have been modified by DNA methylation...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29134540/acute-connexin43-temporal-and-spatial-expression-in-response-to-ischemic-stroke
#8
Moises Freitas-Andrade, Jennifer She, John Bechberger, Christian C Naus, Wun Chey Sin
Connexin43 (Cx43) gap junctions expressed in astrocytes can significantly impact neuronal survival in stroke. However, little is known regarding Cx43 spatial and temporal expression during the initial stages of brain ischemia. Using immunohistochemistry and Western blot analysis, we examined Cx43 spatial and temporal expression as a function of neuronal injury within the first 24 h after permanent middle cerebral artery occlusion (pMCAO). Western blot analysis showed a significant increase in Cx43 protein expression in the core ischemic area at 2 and 3 h after pMCAO...
November 13, 2017: Journal of Cell Communication and Signaling
https://www.readbyqxmd.com/read/29133182/a-novel-method-for-localization-and-ablation-of-conduction-gaps-after-wide-antral-circumferential-ablation-of-pulmonary-veins
#9
Raoul Bacquelin, Raphaël P Martins, Nathalie Behar, Vincent Galand, Baptiste Polin, Jonathan Lacaze, Frédéric Sebag, Christophe Leclercq, Jean-Claude Daubert, Philippe Mabo, Dominique Pavin
BACKGROUND: Atrial fibrillation ablation is often performed by achieving pulmonary vein isolation using the "wide antral circumferential ablation" (WACA) technique, but many pulmonary veins remain connected because of conduction gaps in the ablation line. AIM: To analyse the efficacy of a novel technique based on pacing manoeuvres to detect gaps in an initial WACA lesion. METHODS: Patients referred for radiofrequency atrial fibrillation ablation were enrolled prospectively...
November 10, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29129049/dna-origami-directed-au-nanostar-dimers-for-single-molecule-surface-enhanced-raman-scattering
#10
Swati Tanwar, Krishna Haldar, Tapasi Sen
We demonstrate the synthesis of Au nanostar dimer with tunable interparticle gap and controlled stoichiometry as-sembled on DNA origami. Au nanostars with uniform and sharp tips were immobilized on rectangular DNA origami dimerized structures to create nanoantennas containing monomeric and dimeric Au nanostars. Single Texas red dye was specifically attached in the junction of the dimerized origami which acts as a Raman reporter molecule. The SERS enhancement factors of single Texas red dye located in the conjunction region in the dimer structures having inter-particle gaps of 7 nm and 13 nm are 2 × 1010 and 8 × 109, respectively, which are strong enough for single analyte detec-tion...
November 13, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29123324/three-decades-of-landsat-derived-spring-surface-water-dynamics-in-an-agricultural-wetland-mosaic-implications-for-migratory-shorebirds
#11
Danica Schaffer-Smith, Jennifer J Swenson, Blake Barbaree, Matthew E Reiter
Satellite measurements of surface water offer promise for understanding wetland habitat availability at broad spatial and temporal scales; reliable habitat is crucial for the persistence of migratory shorebirds that depend on wetland networks. We analyzed water extent dynamics within wetland habitats at a globally important shorebird stopover site for a 1983-2015 Landsat time series, and evaluated the effect of climate on water extent. A range of methods can detect open water from imagery, including supervised classification approaches and thresholds for spectral bands and indices...
May 2017: Remote Sensing of Environment
https://www.readbyqxmd.com/read/29122313/has-the-question-of-e-waste-opened-a-pandora-s-box-an-overview-of-unpredictable-issues-and-challenges
#12
REVIEW
Bouchra Bakhiyi, Sabrina Gravel, Diana Ceballos, Michael A Flynn, Joseph Zayed
Despite regulatory efforts and position papers, electrical and electronic waste (e-waste) remains ill-managed as evidenced by the extremely low rates of proper e-waste recycling (e-recycling) worldwide, ongoing illegal shipments to developing countries and constantly reported human health issues and environmental pollution. The objectives of this review are, first, to expose the complexity of e-waste problems, and then to suggest possible upstream and downstream solutions. Exploring e-waste issues is akin to opening a Pandora's box...
January 2018: Environment International
https://www.readbyqxmd.com/read/29121167/basal-cells-show-increased-expression-of-aromatase-and-estrogen-receptor-%C3%AE-in-prostate-epithelial-lesions-of-male-aging-rats
#13
Monica Morais-Santos, Hipácia Werneck-Gomes, Gabriel H Campolina-Silva, Leticia C Santos, Germán A B Mahecha, Rex A Hess, Cleida A Oliveira
Besides androgens, estrogen signaling plays key role in normal development and pathologies of the prostate. Irreversible synthesis of estrogens from androgens is catalyzed by aromatase. Interestingly, animals lacking aromatase do not develop cancer or prostatitis, whereas those with overexpression of aromatase and consequently high estrogen levels, develop prostatitis and squamous metaplasia via estrogen receptor 1 (ERα). Even with this evidence, the aromatase expression in the prostate is controversial. Moreover, little is known about the occurrence of age-dependent variation of aromatase and its association with histopathological changes commonly found in advanced age, a knowledge gap that is addressed herein...
November 7, 2017: Endocrinology
https://www.readbyqxmd.com/read/29121111/genetic-and-physical-mapping-of-anther-extrusion-in-elite-european-winter-wheat
#14
Quddoos H Muqaddasi, Klaus Pillen, Jörg Plieske, Martin W Ganal, Marion S Röder
The production and cultivation of hybrid wheat is a possible strategy to close the yield gap in wheat. Efficient hybrid wheat seed production largely depends on high rates of cross-pollination which can be ensured through high anther extrusion (AE) by male parental lines. Here, we report the AE capacity and elucidate its genetics in 514 elite European winter wheat varieties via genome-wide association studies (GWAS). We observed a wide range of variation among genotypes and a high heritability (0.80) for AE...
2017: PloS One
https://www.readbyqxmd.com/read/29120316/weighing-in-on-canadian-school-based-vision-screening-a-call-for-action
#15
Katie P Bennett, Wendy Maloney
Vision-screening programs are designed to detect common causes of visual impairment and increase the likelihood of early diagnosis and treatment. In the health authority Eastern Health - Newfoundland and Labrador, public health leaders raised a concern about the efficiency and effectiveness of the current non-routine, opportunistic vision screening protocol for school-aged children. An environmental scan of screening practices and programs across Canada was conducted, yielding a wide range of inconsistencies with respect to program type, target population, and screening tools...
November 9, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29120216/bridging-the-gap-learning-of-acoustic-nonadjacent-dependencies-by-a-songbird
#16
Jiani Chen, Carel Ten Cate
Many animal species can detect dependencies between adjacent visual or auditory items in a string. Compared with adjacent dependencies, detecting nonadjacent dependencies, as present in linguistic constructions, is more challenging as this requires detecting a relation between items irrespective of the number and nature of the intervening items. There is limited evidence that nonhuman animals can detect such dependencies. An animal group in which such abilities might be expected is songbirds, which have learned songs consisting of a series of vocal elements given in specific sequences...
July 2017: Journal of Experimental Psychology. Animal Learning and Cognition
https://www.readbyqxmd.com/read/29119383/determination-of-trace-metal-concentration-in-compost-dap-and-tsp-fertilizers-by-neutron-activation-analysis-naa-and-insights-from-density-functional-theory-calculations
#17
Md Sajjadur Rahman, Syed Mohammod Hossain, Mir Tamzid Rahman, Mohammad A Halim, Mohammad Niaz Ishtiak, Mahbub Kabir
Leaching of toxic metals from fertilizers is a growing concern in an agricultural country like Bangladesh due to the serious consequences in health and food chain. Fertilizers used in farming fields and nurseries (plant sales outlet) in the mid-southern part of Bangladesh were collected for the determination of toxic metals. This study employed the neutron activation method and a relative standardization approach. Three standard/certified reference materials, namely NIST coal fly ash 1633b, IAEA-Soil-7, and IAEA-SL-1 (lake sediment), were considered for elemental quantification...
November 8, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29118176/highly-sensitive-detection-of-isoniazid-heteroresistance-in-mycobacterium-tuberculosis-by-deepmelt-assay
#18
Bin Liang, Yaoju Tan, Zi Li, Xueshan Tian, Chen Du, Hui Li, Guoli Li, Xiangyang Yao, Zhongan Wang, Ye Xu, Qingge Li
Detection of heteroresistance of Mycobacterium tuberculosis (MTB) remains challenging using current genotypic drug susceptibility testing methods. Here, we described a melting curve analysis-based approach, termed DeepMelt, that can detect less abundant mutants through selective clamping of the wild-type in mixed populations. Singleplex DeepMelt assay detected 0.01% katG S315T in 10(5) MTB genomes/μL. Multiplex DeepMelt TB/INH detected 1% of mutant species in the four loci associated with isoniazid resistance in 10(4) MTB genomes/μL...
November 8, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29117381/assessment-of-feeding-acceptance-and-injury-of-kerman-pistachios-pistacia-vera-by-brown-marmorated-stink-bug-hemiptera-pentatomidae
#19
Jesús R Lara, Matthew T Kamiyama, Gabriel Hernandez, Justin Nay, Mark S Hoddle, Yulin Gao
In the United States, California (CA) is the primary commercial producer of pistachio nuts, Pistacia vera L. (Anacardiaceae). The brown marmorated stink bug (BMSB), Halyomorpha halys (Stål) (Hemiptera: Pentatomidae), an invasive and polyphagous insect pest from Asia, has established in urban areas in several pistachio-growing counties in CA. Breeding BMSB populations have not been detected in commercial pistachio acreage. However, the detection of BMSB in Kern and Fresno counties, major Kerman pistachio producing areas in CA, underscored key knowledge gaps on BMSB ecology in CA and motivated investigations on the susceptibility of pistachio nuts to BMSB feeding...
September 1, 2017: Journal of Insect Science
https://www.readbyqxmd.com/read/29116118/phononic-crystal-waveguide-transducers-for-nonlinear-elastic-wave-sensing
#20
Francesco Ciampa, Akash Mankar, Andrea Marini
Second harmonic generation is one of the most sensitive and reliable nonlinear elastic signatures for micro-damage assessment. However, its detection requires powerful amplification systems generating fictitious harmonics that are difficult to discern from pure nonlinear elastic effects. Current state-of-the-art nonlinear ultrasonic methods still involve impractical solutions such as cumbersome signal calibration processes and substantial modifications of the test component in order to create material-based tunable harmonic filters...
November 7, 2017: Scientific Reports
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