Nuria Barroso-García, Belén Atienza-Mateo, Iván Ferraz-Amaro, Diana Prieto-Peña, Emma Beltrán, Alfredo Adán, Marisa Hernández-Garfella, Lucía Martínez-Costa, Miguel Cordero-Coma, Manuel Díaz-Llopis, José M Herreras, Olga Maíz-Alonso, Ignacio Torre-Salaberri, Ana De Vicente-Delmás, David Díaz-Valle, Antonio Atanes-Sandoval, Félix Francisco, Santos Insua, Julio Sánchez, Raquel Almodóvar-González, Alejandro Jiménez-Sosa, Oscar Ruiz-Moreno, Myriam Gandía-Martínez, Joan M Nolla, Vanesa Calvo-Río, Santos Castañeda, Miguel A González-Gay, Ricardo Blanco
OBJECTIVE: To compare the efficacy of TNF inhibitors (adalimumab (ADA) and infliximab (IFX)) vs tocilizumab (TCZ) in patients with refractory cystoid macular edema (CME) due to Behçet's disease (BD). METHODS: Multicenter study of patients with BD-associated CME refractory to conventional and/or biological immunosuppressive drugs. From a cohort of 177 patients treated with anti-TNF and 14 patients treated with TCZ, we selected those with CME at baseline. We analyzed the evolution of macular thickness (main outcome), best-corrected visual acuity (BCVA) and intraocular inflammation (Tyndall and vitritis) from baseline up to 4 years in the 3 groups mentioned...
February 2023: Seminars in Arthritis and Rheumatism