Harry B Lengel, Junting Zheng, Kay See Tan, Corinne C Liu, Bernard J Park, Gaetano Rocco, Prasad S Adusumilli, Daniela Molena, Helena A Yu, Gregory J Riely, Manjit S Bains, Valerie W Rusch, Mark G Kris, Jamie E Chaft, Bob T Li, James M Isbell, David R Jones
OBJECTIVE: Targeted therapy improves outcomes in patients with advanced-stage non-small cell lung cancer (NSCLC) and in the adjuvant setting, but data on its use before surgery are limited. We sought to investigate the safety and feasibility of preoperative targeted therapy in patients with operable NSCLC. METHODS: We retrospectively reviewed 51 patients with clinical stage I to III NSCLC who received targeted therapy, alone or in combination with chemotherapy, before surgical resection with curative intent, treated from 2004 to 2021...
November 17, 2022: Journal of Thoracic and Cardiovascular Surgery