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https://www.readbyqxmd.com/read/29773965/funds-allocation-in-npos-the-role-of-administrative-cost-ratios
#1
Christian Burkart, Tina Wakolbinger, Fuminori Toyasaki
Performance measurement of Non-Profit Organizations (NPOs) is of increasing importance for aid agencies, policy-makers and donors. A widely used benchmark for measuring the efficiency of NPOs is the overhead cost ratio, consisting of the total money spent on administration and fundraising relative to the budget. Donors generally favor a lower overhead cost ratio as it ensures that more money directly reaches beneficiaries. Unlike fundraising expenses, administrative costs do not contribute to advertising the actions of an NPO even though they account for a significant proportion of overhead cost...
2018: Central European Journal of Operations Research
https://www.readbyqxmd.com/read/29767559/g-protein-pathway-suppressor-2-gps2-enhanced-the-renal-large-conductance-ca2-activated-potassium-channel-expression-via-inhibiting-erk-1-2-signaling-pathway
#2
Zhizhi Zhuang, Jia Xiao, Xinxin Chen, Xiaohan Hu, Ruidian Li, Shan Chen, Xiuyan Feng, Saier Shen, He-Ping Ma, Jieqiu Zhuang, Hui Cai
G-protein pathway suppressor 2 (GPS2) is a multifunctional protein and transcriptional regulation factor that is involved in the G-protein mitogen-activated protein kinase (MAPK) signaling pathway. It has been shown that the MAPK signaling pathway plays an important role in the regulation of renal large conductance Ca2+ activated potassium (BK) channels. In this study, we investigated the effects of GPS2 on BK channel activity and protein expression. In HEK BK stably-expressing cells transfected with either GPS2 or its pCMV vector control, a single cell recording showed that GPS2 significantly increased BK channel activity (NPo), increasing BK open probability (Po) and channel number (N) compared to the control...
May 16, 2018: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/29730093/adverse-events-and-satisfaction-with-use-of-intranasal-midazolam-for-emergency-department-procedures-in-children
#3
Laurie Malia, V Matt Laurich, Jesse J Sturm
PURPOSE: Procedural sedation is commonly performed in the emergency department (ED). Having safe and fast means of providing sedation and anxiolysis to children is important for the child's tolerance of the procedure, parent satisfaction and efficient patient flow in the ED. OBJECTIVE: To evaluate fasting times associated with the administration of intranasal midazolam (INM) and associated complications. Secondary objectives included assessing provider and caregiver satisfaction scores...
April 30, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29713174/reac-neuromodulation-treatments-in-subjects-with-severe-socioeconomic-and-cultural-hardship-in-the-brazilian-state-of-par%C3%A3-a-family-observational-pilot-study
#4
José Alfredo Coelho Pereira, Arianna Rinaldi, Vania Fontani, Salvatore Rinaldi
Purpose: The purpose of this preliminary observational study was to evaluate the usefulness of a humanitarian initiative, aimed at improving the neuropsychological and behavioral attitude of children with severe socioeconomic and cultural hardship, in the Brazilian state of Pará. This humanitarian initiative was realized through the administration of two neuromodulation protocols, with radioelectric asymmetric conveyor (REAC) technology. During several years of clinical use, the REAC neuromodulation protocols have already proved to be effective in countering the effects of environmental stress on neuropsycho-physical functions...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29701888/evaluating-gaps-in-care-of-malnourished-patients-on-general-medicine-floors-in-an-acute-care-setting
#5
Rachel Chambers, Joanna Bryan, Deanna Jannat-Khah, Emily Russo, Louise Merriman, Renuka Gupta
BACKGROUND: As described in detail in the literature, patients identified with malnutrition are at increased risk for poor clinical outcomes. Despite this knowledge, malnourished patients do not always receive optimal nutrition management while admitted into a hospital because of what we describe as gaps in care throughout their admission. We hypothesized that the 3 main gaps in care were poor dietitian-doctor communication, excessive time spent nil per os (NPO) for procedures and testing, and/or inaccurate or incomplete dietary discharge instructions...
April 27, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29690961/shortened-preoperative-fasting-time-to-allow-oral-rehydration-solution-clear-liquid-up-to-two-hours-before-elective-major-surgery-in-adults
#6
Jay N Shah, Shantabir Maharjan, Rajan Gurung
OBJECTIVE: To generate evidence of feasibility to allow clear liquid 2 hours before elective surgery. STUDY DESIGN: Cross-sectional observational study. PLACE AND DURATION OF STUDY: The Department of Surgery, Patan Hospital, Patan Academy of Health Sciences, Nepal, from October to December 2016. METHODOLOGY: One hundred consecutive adult elective major surgery patients of American Society of Anesthesiologist criteria 1 or 2 were enrolled...
May 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29671361/liposomal-quercetin-potentiates-maxi-k-channel-openings-in-smooth-muscles-and-restores-its-activity-after-oxidative-stress
#7
Mariia I Melnyk, Dariia O Dryn, Lina T Al Kury, Alexander V Zholos, Anatoly I Soloviev
The effects of quercetin-loaded liposomes (PCL-Q) and their constituents, that is, free quercetin (Q) and 'empty' phosphatidylcholine vesicles (PCL), on maxi-K channel activity were studied in single mouse ileal myocytes before and after H2 O2 -induced oxidative stress. Macroscopic Maxi-K channel currents were recorded using whole-cell patch clamp techniques, while single BKCa channel currents were recorded in the cell-attached configuration. Bath application of PCL-Q (100 μg/ml of lipid and 3 μg/ml of quercetin) increased single Maxi-K channel activity more than threefold, from 0...
April 19, 2018: Journal of Liposome Research
https://www.readbyqxmd.com/read/29653310/a-self-template-and-self-activation-co-coupling-green-strategy-to-synthesize-high-surface-area-ternary-doped-hollow-carbon-microspheres-for-high-performance-supercapacitors
#8
Meng Gao, Jianwei Fu, Minghuan Wang, Kai Wang, Shaomin Wang, Zhiwei Wang, Zhimin Chen, Qun Xu
Development of facile and cost-effective routes to achieve hierarchical porous and heteroatoms-doped carbon architectures is urgently needed for high-performance supercapacitor application. In our study, ternary-doped (nitrogen, phosphorus and oxygen) hollow carbon microspheres (NPO-HCSs) are fabricated by one-step pyrolysis of single poly(cyclotriphosphazene-co-phloroglucinol) (PCPP) microsphere, which is generated through a facile polymerization between hexachlorocyclotriphosphazene and phloroglucinol at mild conditions...
April 6, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29602238/improving-health-literacy-in-a-japanese-community-population-a-pilot-study-to-develop-an-educational-programme
#9
Hirono Ishikawa, Ikuko Yamaguchi, Don Nutbeam, Mio Kato, Tsuyoshi Okuhara, Masafumi Okada, Takahiro Kiuchi
OBJECTIVE: Although a growing number of interventional studies on health literacy have been conducted recently, the majority were designed in clinical settings, focusing mainly on functional health literacy. This study evaluated a programme designed to improve health literacy in a community population, with a scope of going beyond functional health literacy. METHODS: In collaboration with an Approved Specified Nonprofit organization (NPO), we evaluated a five-session programme designed to provide basic knowledge on health-care policy and systems, current issues in health care in Japan, patient roles and relationships with health-care providers and interpersonal skills...
March 30, 2018: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29535984/predictive-factors-affecting-the-clinical-course-of-patients-with-diverticulitis-who-needs-hospital-management
#10
Taeyoung Yoo, Keun Ho Yang, Jungbin Kim, Inseok Park, Hyunjin Cho, Geumhee Gwak, Byung Noe Bae, Ki Hwan Kim
Purpose: The aim of this study is to determine the predictable factors that affect the clinical course, especially the hospital stay, the operation performed, and to determine factors that will be helpful in deciding whether in-hospital or outpatient treatment is appropriate. Methods: We retrospectively collected medical data for patients who had been diagnosed with acute diverticulitis at Inje University Sanggye Paik Hospital between January and December 2016. In total, 117 patients were enrolled in this study...
February 2018: Annals of Coloproctology
https://www.readbyqxmd.com/read/29526302/effect-of-number-of-pontics-and-impression-technique-on-the-accuracy-of-four-unit-monolithic-zirconia-fixed-dental-prostheses
#11
Woong Ki Kim, Sunjai Kim
STATEMENT OF PROBLEM: Because of their relatively small scanning area, intraoral scanners may result in less accurate fixed dental prostheses (FDPs) than do laboratory scanners. PURPOSE: The purpose of this in vitro study was to evaluate the accuracy of monolithic zirconia FDPs with different numbers of pontics fabricated with different impression techniques. MATERIAL AND METHODS: The mandibular right premolars and molars of an acrylic resin model were prepared to receive 4-unit FDPs...
March 8, 2018: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29525273/appropriate-use-of-total-parenteral-nutrition-in-children-with-perforated-appendicitis
#12
Yasmine Yousef, Fouad Youssef, Michael Homsy, Trish Dinh, Hayden Stagg, Robin Petroze, Robert Baird, Jean-Martin Larberge, Dan Poenaru, Pramod Puligandla, Kenneth Shaw, Sherif Emil
BACKGROUND: Total parenteral nutrition (TPN) is often used in children with perforated appendicitis, despite the absence of clear indications. We assessed the validity of specific clinical indications for initiation of TPN in this patient cohort. METHODS: Data were gathered prospectively on duration of nil per os (NPO) status and TPN use in a cohort of children treated under a perforated appendicitis protocol during a 19-month period. TPN was started in the immediate postoperative period in patients who had generalized peritonitis and severe intestinal dilatation at operation, or later per the discretion of the attending surgeon...
May 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29493229/synthesis-structure-and-vibrational-properties-of-ph-4-p-2-npo-2-cl-4-and-ph-4-p-2-puo-2-cl-4-complexes
#13
David D Schnaars, Richard E Wilson
The synthesis, structure, and vibrational properties are presented for an isostructural series of Np(VI) and Pu(VI) complexes of the form [Ph4 P]2 AnO2 Cl4 , where An = Np(VI) or Pu(VI). The reported complexes are readily synthesized in ambient laboratory conditions, and their molecular structures were determined using single crystal X-ray diffraction. Their vibrational spectra were studied using a combination of Raman and FT-IR vibrational spectroscopies. Analysis of the vibrational spectra and force constants highlight the periodic properties associated with the actinide contraction and filling of the 5f electronic shells...
March 19, 2018: Inorganic Chemistry
https://www.readbyqxmd.com/read/29486640/the-level-of-personality-organization-and-revictimization-in-lives-of-child-sexual-abuse-survivors
#14
Agnieszka Izdebska, Maria Beisert
Previous research has documented that women who were sexually abused in childhood are also often victims of sexual abuse in adulthood. In the current study, we investigated the relationship between the phenomenon of sexual revictimization and personality organization (PO) conceptualized in accordance with the Otto Kernberg's theory. The central hypothesis was that women with borderline personality organization (BPO) and neurotic personality organization (NPO) differ in terms of the occurrence of revictimization and its features...
February 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29466671/lipopolysaccharide-stimulates-bk-channel-activity-in-bladder-umbrella-cells
#15
Ming Lu, Jian-Ri Li, Lery Alvarez-Lugo, Yan Li, Shan Yu, Xuanhao Li, Benkang Shi, Toby C Chai
Bladder urothelium plays an active role in response to bacterial infection. There is little known about the electrophysiological activity in urothelial cells in this process. We used a non-enzymatic method to isolate bladder urothelial tissue and to patch clamp umbrella cells in situ. A 200pS conductance potassium (K+ ) channel was detected from female C57BL6 mice. Of 58 total patches, 17.2% patches displayed the 200pS K+ conductance channel. This K+ conductance channel showed Ca2+ sensitivity and voltage dependence...
February 21, 2018: American Journal of Physiology. Cell Physiology
https://www.readbyqxmd.com/read/29389984/systematic-dysphagia-screening-and-dietary-modifications-to-reduce-stroke-associated-pneumonia-rates-in-a-stroke-unit
#16
Yvonne Teuschl, Michaela Trapl, Paulina Ratajczak, Karl Matz, Alexandra Dachenhausen, Michael Brainin
BACKGROUND AND PURPOSE: While formal screening for dysphagia following acute stroke is strongly recommended, there is little evidence on how multi-consistency screening and dietary modifications affect the rate of stroke-associated pneumonia (SAP). This observational study reports which factors affect formal screening on a stroke-unit and how dietary recommendations relate to SAP. METHOD: Analyses from a database including 1394 patients admitted with acute stroke at our stroke-unit in Austria between 2012 and 2014...
2018: PloS One
https://www.readbyqxmd.com/read/29344461/using-role-plays-as-an-empathy-education-tool-for-ophthalmology-postgraduate
#17
Kirti Singh, Mainak Bhattacharyya, Vikas Veerwal, Arshi Singh
Purpose: To assess the role of an "empathy sensitizing module" (ESM) in ophthalmology postgraduates in promoting effective empathetic communication. Methodology: Thirty-nine ophthalmology postgraduates were taught effective empathetic communication using specially designed module, comprising of five illustrative role-plays. We evaluated the impact of the training by (a) self-assessment of empathy quotient by residents using Jefferson Scale of Empathy (JSE scale) before and 6 weeks after ESM training and (b) nonparticipant observation (NPO) by trained faculty in real-life settings over the next 4 months...
December 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29216722/the-influence-of-orthodontic-non-extraction-treatment-on-the-change-in-the-inclination-and-position-of-incisors-in-the-europoid-race
#18
A Koniarova, E Sedlata Juraskova, M Spidlen, D Statelova
AIM: To detect post-treatment change in the inclination and position of incisors in cases treated with orthodontic non- extraction therapy. MATERIALS AND METHODS: The group consisted of 102 patients without extractions in lower and upper dental arch during orthodontic treatment. Cephalogram examination evaluated the position of the lower incisor to point A by Downs-pogonion line (-1 to APo) and inclination of the lower incisor to mandibular line (-1 to ML), position of the upper incisor to nasion-pogonion line (+1 to NPo), inclination of the upper incisor to nasion-sella line (+1 to NS) and the size of the inter-incisival angle between upper and central lower incisor (-1 to +1)...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/29187086/nutrition-management-of-home-parenteral-nutrition-among-patients-with-enterocutaneous-fistula-in-the-sustain-registry
#19
Charlene Compher, Marion F Winkler, Peggi Guenter, Ezra Steiger
BACKGROUND: Home parenteral nutrition (HPN) is a vital therapy for patients who have the diagnosis of enterocutaneous fistula (ECF), yet little is known about how these patients are managed. This research compares nutrition management of adults with ECF as the indication for HPN therapy to those with other indications. METHODS: This is an analysis of data from adult HPN patients in the Sustain registry enrolled between August 2011 and February 2014 who have the diagnosis of ECF or other indication for HPN who served as the control group...
February 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29173380/clinical-issues-december-2017
#20
Mary J Ogg
Bed bugs Key words: bed bugs, pest management, infestation, transmission. Warming irrigation fluids Key words: irrigation fluid, warming fluid, hypothermia, warming cabinet. Fasting before surgery Key words: fasting, NPO, liquids, solids. Advanced cardiac life support requirements for perioperative nurses Key words: advanced cardiac life support, ACLS certification, pediatric advanced life support, PALS certification, basic life support.
December 2017: AORN Journal
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