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https://www.readbyqxmd.com/read/28924546/sirenomelia-associated-with-hypoplastic-left-heart-in-a-newborn
#1
H Turgut, R Ozdemir, I K Gokce, C Karakurt, A Karadag
Sirenomelia, also known as "mermaid malformation/syndrome," is a rare, serious congenital anomaly characterized by variable degrees of fusion of the lower limbs and associated with severe malformations of vertebral, genitourinary, cardiovascular system and single umbilical artery. The first pregnancy of a 25-year-old woman resulted in one twin born by Cesarian section at 32 weeks' gestation, who was referred to our hospital with cyanosis, a congenital anomaly and respiratory distress. On physical examination, there was no urogenital region and anal fissure and gender was indeterminate...
June 30, 2017: Balkan Journal of Medical Genetics: BJMG
https://www.readbyqxmd.com/read/28803005/safety-and-feasibility-of-therapeutic-platelet-depletion-with-spectra-optia-in-a-pregnant-woman
#2
Roman Małachowski, Olga Grzybowska-Izydorczyk, Nelly Besson, Anna Szmigielska-Kapłon, Mateusz Nowicki, Agnieszka Wierzbowska
INTRODUCTION: Thrombocytapheresis is an alternative treatment beneficial in rare circumstances, when cytoreductive agents are contraindicated, drug therapy gave no response or the expected response would be too slow. Here we present a case of a pregnant woman who underwent 5 thrombocytaphereses using Spectra Optia device to reduce circulating platelets (PLT) count and prepare for Cesarian section. PATIENT CHARACTERISTICS AND PERFORMED TREATMENT: A 39-year-old woman with diagnosed chronic myeloid leukemia (CML) was treated with interferon because of too high PLT count...
July 27, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28743311/hypercapnic-respiratory-failure-during-pregnancy-due-to-polymyositis-related-respiratory-muscle-weakness-a-case-report
#3
Husain Shabbir Ali, Ibrahim Fawzy Hassan, Saibu George, Abdalrazig Elsadig Fadlelmula
BACKGROUND: Polymyositis is a rare medical disorder complicating pregnancy. Ventilatory muscle weakness leading to respiratory failure is an uncommon manifestation of this autoimmune disease. We report a case of life-threatening hypercapnic respiratory failure due to polymyositis-related respiratory muscle weakness in a pregnant woman. CASE PRESENTATION: A 31-year-old, African woman in her second trimester of pregnancy presented to the emergency department with fever, shortness of breath and muscle weakness...
July 26, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28613023/variations-in-reporting-of-outcomes-in-randomized-trials-on-diet-and-physical-activity-in-pregnancy-a-systematic-review
#4
Ewelina Rogozińska, Nadine Marlin, Fen Yang, Jodie M Dodd, Kym Guelfi, Helena Teede, Fernanda Surita, Dorte M Jensen, Nina R W Geiker, Arne Astrup, SeonAe Yeo, Tarja I Kinnunen, Signe N Stafne, Jose G Cecatti, Annick Bogaerts, Hans Hauner, Ben W Mol, Tânia T Scudeller, Christina A Vinter, Kristina M Renault, Roland Devlieger, Shakila Thangaratinam, Khalid S Khan
AIM: Trials on diet and physical activity in pregnancy report on various outcomes. We aimed to assess the variations in outcomes reported and their quality in trials on lifestyle interventions in pregnancy. METHODS: We searched major databases without language restrictions for randomized controlled trials on diet and physical activity-based interventions in pregnancy up to March 2015. Two independent reviewers undertook study selection and data extraction. We estimated the percentage of papers reporting 'critically important' and 'important' outcomes...
June 14, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28600901/influences-of-environmental-bacteria-and-their-metabolites-on-allergies-asthma-and-host-microbiota
#5
REVIEW
G Jatzlauk, S Bartel, H Heine, M Schloter, S Krauss-Etschmann
The prevalence of allergic diseases and asthma has dramatically increased over the last decades, resulting in a high burden for patients and healthcare systems. Thus, there is an unmet need to develop preventative strategies for these diseases. Epidemiological studies show that reduced exposure to environmental bacteria in early life (eg, birth by cesarean section, being formula-fed, growing up in an urban environment or with less contact to various persons) is associated with an increased risk to develop allergies and asthma later in life...
June 10, 2017: Allergy
https://www.readbyqxmd.com/read/28080219/adipose-tissue-insulin-resistance-in-gestational-diabetes
#6
Batbayar Tumurbaatar, Aaron T Poole, Gayle Olson, Michel Makhlouf, Hanaa S Sallam, Shwetha Thukuntla, Sucharitha Kankanala, Obos Ekhaese, Guillermo Gomez, Manisha Chandalia, Nicola Abate
BACKGROUND: Gestational diabetes mellitus (GDM) is a metabolic disorder characterized by insulin resistance (IR) and altered glucose-lipid metabolism. We propose that ectonucleotide pyrophosphate phosphodiesterase-1 (ENPP1), a protein known to induce adipocyte IR, is a determinant of GDM. Our objective was to study ENPP1 expression in adipose tissue (AT) of obese pregnant women with or without GDM, as well as glucose tolerance in pregnant transgenic (Tg) mice with AT-specific overexpression of human ENPP1...
March 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27703570/two-pregnancies-with-a-different-outcome-in-a-patient-with-alport-syndrome
#7
Biljana Gerasimovska Kitanovska, Vesna Gerasimovska, Vesna Livrinova
BACKGROUND: Alport syndrome is a genetic disease that progresses to chronic kidney failure, with X-linked, autosomal dominant or autosomal recessive type of inheritance. Women are generally carriers of the mutation and have a milder form of the disease. During pregnancy, they have an increased risk of impaired kidney function and preeclampsia. CASE PRESENTATION: A 27-year old woman, gravida 1, para 0, in her 23rd gestational week came to the outpatient unit of the University Clinic of Nephrology for the first time because of slowly progressing proteinuria and Alport syndrome...
September 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27562398/subgroup-differences-in-the-associations-between-dog-exposure-during-the-first-year-of-life-and-early-life-allergic-outcomes
#8
G Wegienka, S Havstad, H Kim, E Zoratti, D Ownby, K J Woodcroft, C C Johnson
BACKGROUND: The effect of dog exposure on the risk of children developing allergic disease remains controversial. Many analyses have not considered that associations may vary within population subgroups. OBJECTIVE: To examine whether associations between living with a dog in the first year of life and allergic outcomes vary within subgroups selected a priori (race, gender and delivery mode). METHODS: Black (n = 496) and White (n = 196) children enrolled in the WHEALS birth cohort study had a clinical examination at age 2 years to assess eczema and allergen-specific IgE (sIgE) and perform skin prick testing (SPT)...
January 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27524922/a-case-of-optic-nerve-hypoplasia-and-anterior-segment-abnormality-associated-with-facial-cleft
#9
Tomoko Miyake, Shota Kojima, Tetsuya Sugiyama, Mari Ueki, Jun Sugasawa, Hidehiro Oku, Kensuke Tajiri, Yuka Shigemura, Koichi Ueda, Atsuko Harada, Mami Yamasaki, Takumi Yamanaka, Hidetsuna Utsunomiya, Tsunehiko Ikeda
INTRODUCTION: The incidence of facial cleft is rare and ranges between 1.43 and 4.85 per 100,000 births. To date, there have been few reports of detailed ophthalmologic examinations performed in cases of facial cleft. Here, we report a case of optic-nerve hypoplasia and anterior segment abnormality associated with facial cleft. CASE REPORT: A 9-day-old female infant was delivered by cesarian section at 34 weeks of gestational age (the second baby of twins) and weighed 2,276 g upon presentation...
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/27280111/postpartum-domperidone-use-in-british-columbia-a-retrospective-cohort-study
#10
Kate Smolina, Steven G Morgan, Gillian E Hanley, Tim F Oberlander, Barbara Mintzes
BACKGROUND: Domperidone is commonly used off-label to stimulate milk production in mothers who have low milk supply. The aim of this study was to describe trends, patterns and determinants of postpartum domperidone use. METHODS: This is a retrospective, population-based study involving all women with a live birth between Jan. 1, 2002, and Dec. 31, 2011, in the province of British Columbia. We examined administrative data sets containing person-specific information on filled prescriptions and use of medical services, and we used logistic regression to examine associations between domperidone use and maternal characteristics...
January 2016: CMAJ Open
https://www.readbyqxmd.com/read/27123542/impact-of-mode-of-delivery-on-skin-microcirculation-in-term-healthy-newborns-within-the-first-day-of-life
#11
COMPARATIVE STUDY
Ferit Kulali, Ebru Ergenekon, Selma Aktas, Ebru Kazanci, Sezin Unal, İbrahim Hirfanoğlu, Esra Önal, Canan Türkyilmaz, Esin Koç, Yildiz Atalay
BACKGROUND: Microcirculation is an important component of hemodynamic physiology. It can be assessed simply by clinical scores or by a variety of techniques including sidestream dark field (SDF) imaging and peripheral perfusion index (PI) measurements. Mode of delivery may have affects on microcirculation during transitional period. The aim of this study was to compare skin microcirculation in newborns born via vaginal delivery (VD) or cesarian section (C/S). METHODS: Term healthy newborns not requiring NICU admission were included...
March 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27052598/effects-of-initial-body-mass-index-on-development-of-gestational-diabetes-in-a-rural-sri-lankan-population-a-case-control-study
#12
C J Kande Vidanalage, U Senarth, K D Silva, U Lekamge, I J Liyanage
AIM: High pre-pregnancy body mass index (BMI) and excessive pregnancy weight gain lead to higher incidence of gestational diabetes mellitus (GDM). Aim of the study was to assess the effects of initial BMI and pregnancy weight gain on development of GDM in a rural Sri Lankan population. It was also hypothesized that these effects could be more pronounced in shorter mothers. METHODS: A case-control study was conducted at two rural hospitals in Sri Lanka. A case was defined as a pregnant mother admitted for the completion of pregnancy and diagnosed to have GDM (n=99)...
April 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/27008239/delivery-after-external-cephalic-version-is-there-an-increased-rate-of-cesarian-section
#13
Victor Lago Leal, Tamara Pradillo Aramendi, Estefania Nicolas Montero, Vanesa Ocaña Martínez, Pablo Del Barrio Fernández, Luis Martínez-Cortés
BACKGROUND: The aim of this study was to compare the obstetric outcomes after successful external cephalic version (cases) with a group of pregnant women with a spontaneous cephalic fetal position at delivery (controls). METHODS: Retrospective review of the cohort of study was performed at the University Hospital of Getafe (Madrid, Spain) between January 2012 and January 2013. SAMPLE POPULATION: 1516 patients (48 cases; 1468 controls). We compared the type of delivery in pregnant women after ECV performed successfully (cases) with spontaneous cephalic presentations (controls)...
April 2016: Minerva Ginecologica
https://www.readbyqxmd.com/read/26956607/intraocular-pressure-in-infants-and-its-association-with-hormonal-changes-with-vaginal-birth-versus-cesarean-section
#14
Ahmet Elbay, Ugur Celik, Burcu Celik, Omer Faruk Ozer, Gokhan Kilic, Julide Canan Umurhan Akkan, Bilge Tanyeri Bayraktar, Nilufer Zorlutuna Kaymak
To investigate cord arterial blood sample and the relationship between birth stress and intraocular pressure in infants at 5 min after delivery. The IOP measurements were taken using Tonopen-Avia tonometer to 158 newborns (158 eyes) at 5th min after birth, in a university hospital. Cord blood was collected within 3 min after delivery. Intraocular pressure, gender, gestation period, mode of delivery, and birth weight of newborns were noted from medical records. Sixty-two babies were delivered by normal vaginal delivery (NVD) and 96 by cesarian section (C/S)...
December 2016: International Ophthalmology
https://www.readbyqxmd.com/read/26837397/late-presenting-developmental-dysplasia-of-the-hip-in-jordanian-males-a-retrospective-hospital-based-study
#15
Omar Q Samarah, Fadi A Al Hadidi, Mohammad Q Hamdan, Ashraf T Hantouly
OBJECTIVES: To describe the pattern of developmental dysplasia of the hip (DDH) in late presenting Jordanian male patients and identify the risk factors and associated findings. METHODS: This is a retrospective study of 1145 male patients who attended the Pediatric Orthopedic Clinic for a DDH check up. This study was carried out in the Orthopedic Section, Special Surgery Department, Faculty of Medicine, The University of Jordan, Amman, Jordan between March 2011 and October 2014...
February 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/26691208/acardiac-twinning-high-resolution-three-dimensional-reconstruction-of-a-low-resistance-case
#16
Monique G J T B van Lier, Enrico Lopriore, Frank P H A Vandenbussche, Geert J Streekstra, Maria Siebes, Peter G J Nikkels, Dick Oepkes, Martin J C van Gemert, Jeroen P H M van den Wijngaard
BACKGROUND: Acardiac twinning is a rare anomaly of monochorionic twin pregnancies. Acardiac fetuses lack a functional heart but are passively perfused by arterial blood from their pump co-twin. Although four acardiac morphological types have been classified, the various paths of anatomical and circulatory acardiac twin development, and the potential influence of acardiac size and perfusion flow as possible predictors of pump twin morbidity and mortality are poorly understood. This report presents the first high resolution three-dimensional reconstruction of the vasculature of an acardiac twin by cryomicrotome imaging...
March 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/26660880/is-parturition-timing-machinery-related-to-the-number-of-inhibitor-cd94-nkg2a-positive-uterine-natural-killer-cells
#17
E Mazi, Z Altunkaynak, I Aydin, I Kocak, D Guven, A P Turkmen, A Yildiran
PURPOSE: Prematurity is the most common cause of infant mortality and morbidity. To prevent this, the timing of parturition and its mechanisms should be understood. It is likely that inhibitor CD94/NKG2A positive decidual natural killer cells (uNK) provide for the continuation of pregnancy. Here, we aimed to evaluate whether CD94/NKG2A positive uNK cells are highest in elective cesarian section (C/S) (suggesting ongoing gestation), moderate in normal full-term birth, and lowest in pre-eclamptic parturition...
August 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/26629223/chorangiocarcinoma-a-case-report-and-clinical-review
#18
Bin Huang, Yan-Ping Zhang, Dan-Fang Yuan, Rui Yang, Chun Wang, Rui-Fang Wu
OBJECTIVE: We describe a case of chorangiocarcinoma, a chorangioma covered by an abnormal trophoblastic proliferation, presenting in a term placenta and in an asymptomatic pregnancy. Evidence of metastasis was found on follow-up of the mother. MATERIALS AND METHODS: The lesion Was diagnosed by pathologic examination after cesarian section at term for fetal macrosomia, performed because of the abnormal gross findings in the placenta. After uncomplicated delivery, a thealthy child was born and the placent was expelled completely...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26355308/cesarian-section-higher-rate-and-higher-challenges
#19
REVIEW
Sh Koridze, N Kintraia, P Machavariani
There is evidence that perinatal morbidity and mortality has not changed - caesarean section rate increased and data remained stable and rate of intro and post operative complications was increased. There is another view of the picture: the right of patient to choose mode of delivery and the reality, that the number of patients with prior caesarian section and number patient and physician prefer caesarean section. The following topics are discussed as well: age of pregnant woman, macrosomia and intrauterine growth restriction, malpresentation, multiple gestation, preeclampsia, BMI, role of assisted reproductive technologies, electronic monitoring of fetal heart rate in labor, induction of labor...
September 2015: Georgian Medical News
https://www.readbyqxmd.com/read/25907449/changes-in-the-blood-serum-levels-of-the-costimulatory-soluble-b7-h4-molecule-in-pregnant-women-during-the-peripartal-phase
#20
Pawel Mach, Alexandra Gellhaus, Lukasz Wicherek, Boerge Schmidt, Rainer Kimmig, Sabine Kasimir-Bauer, Angela Köninger
PROBLEM: B7-H4, a transmembrane protein that negatively regulates T lymphocytes, seems to play a role in the suppression of the im\mune response at the maternal-fetal interface. The aim of this study was to compare the blood serum concentration levels of soluble B7-H4 (sB7-H4) prepartal and postpartal in both women who experienced spontaneous onset of labor and those who underwent elective cesarian section. METHOD OF STUDY: Blood was obtained from 30 prepartal and postpartal women who delivered at the University Hospital of Essen between 2011 and 2012...
September 2015: American Journal of Reproductive Immunology: AJRI
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