Rudolf A Werner, Xinyu Chen, Constantin Lapa, Kazuhiro Koshino, Steven P Rowe, Martin G Pomper, Mehrbod S Javadi, Takahiro Higuchi
Although single-photon-emitting radiotracers have long been the standard for renal functional molecular imaging, recent years have seen the development of positron emission tomography (PET) agents for this application. We provide an overview of renal radionuclide PET radiotracers, in particular focusing on novel 18 F-labelled and 68 Ga-labelled agents. Several reported PET imaging probes allow assessment of glomerular filtration rate, such as [68 Ga]ethylenediaminetetraacetic acid ([68 Ga]EDTA), [68 Ga]IRDye800-tilmanocept and 2-deoxy-2-[18 F]fluorosorbitol ([18 F]FDS))...
August 2019: European Journal of Nuclear Medicine and Molecular Imaging