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https://www.readbyqxmd.com/read/27926981/efficacy-of-allergen-immunotherapy-in-reducing-the-likelihood-of-developing-new-allergen-sensitizations-a-systematic-review
#1
REVIEW
Danilo Di Bona, Antonella Plaia, Maria Stefania Leto-Barone, Simona La Piana, Luigi Macchia, Gabriele Di Lorenzo
BACKGROUND: Guidelines and position papers indicate that allergen immunotherapy (AIT) is the only disease-modifying treatment, including prevention of the onset of new allergen sensitizations. However, this preventive effect was shown by only a few observational studies. Our aim was to systematically review the efficacy of AIT in preventing the onset of new allergen sensitizations. METHODS: Computerized bibliographic searches of MEDLINE, EMBASE, and the Cochrane Library (through June 2015) were supplemented with manual searches of reference lists...
December 7, 2016: Allergy
https://www.readbyqxmd.com/read/27925602/bayesian-intent-prediction-in-object-tracking-using-bridging-distributions
#2
Bashar I Ahmad, James K Murphy, Patrick M Langdon, Simon J Godsill
In several application areas, such as human computer interaction, surveillance and defence, determining the intent of a tracked object enables systems to aid the user/operator and facilitate effective, possibly automated, decision making. In this paper, we propose a probabilistic inference approach that permits the prediction, well in advance, of the intended destination of a tracked object and its future trajectory. Within the framework introduced here, the observed partial track of the object is modeled as being part of a Markov bridge terminating at its destination, since the target path, albeit random, must end at the intended endpoint...
December 2, 2016: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/27925389/the-long-term-immunological-effects-of-alloferon-and-its-analogues-in-the-mealworm-tenebrio-molitor
#3
Elżbieta Czarniewska, Arkadiusz Urbański, Szymon Chowański, Mariola Kuczer
The subject of this paper is a search for the long-term immunological effects of alloferon and 3 structural analogues of alloferon, which were earlier characterised by the highest pro-apoptotic activity in Tenebrio molitor. The differences in the actions of these peptides on immune response were observed. Alloferon increased nodulation and significantly phenoloxidase activity in the haemolymph of experimentally infected T. molitor. However, [Phe(p-NH2 )(1) ]- and [Phe(p-OMe)(1) ]-alloferon strongly inhibited cellular and humoral defense of the mealworm against Staphylococcus aureus infection...
December 7, 2016: Insect Science
https://www.readbyqxmd.com/read/27925119/breathalyzer-test-results-and-refusals-to-take-the-test-of-drivers-intercepted-under-the-dui-spot-check-campaign-in-rio-de-janeiro
#4
Rafael Tavares Jomar, Dandara de Oliveira Ramos, Ângela Maria Mendes Abreu
Abstract This paper involved a cross-sectional study that evaluated the results and refusals to take the breathalyzer test among drivers intercepted by the Driving Under the Influence (DUI) Spot-Check Campaign (Operação Lei Seca) in the capital of Rio de Janeiro and Baixada Fluminense. It was conducted using data provided by the State Government which were collected from drivers intercepted in the months of December 2013 and January 2014. Descriptive analysis was conducted of the sample and of the association between gender, age and location variables with the result of the breathalyzer test and refusal to take the test using a logistic regression model...
December 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27925106/the-moscow-and-brasilia-declarations-on-road-safety-a-parallel-between-two-moments-in-health
#5
Roberto Victor Pavarino
Two high-level multisectoral global conferences on road traffic safety (Moscow, 2009 and Brasilia, 2015), held under the auspices of the United Nations, adopted formal declarations on both occasions. Given the potential of these documents to establish positions, propose guidelines, policies and legal frameworks, this paper compares these charters, in order to identify the emphases, expectations and horizons indicated at each moment, highlighting their health-related items. We describe the WHO's involvement with road safety, considering the ways this relationship signaled the health sector's connection with the theme...
December 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27925033/new-carbohydrazide-derivatives-of-1h-pyrazolo-3-4-b-pyridine-and-trypanocidal-activity
#6
Raquel R S Salvador, Murilo L Bello, Igor R L Barreto, Maria A F Vera, Estela M F Muri, Sérgio DE Albuquerque, Luiza R S Dias
This paper reports the in vitro trypanocidal activity evaluation of new carbohydrazide derivatives from 3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine, substituted at C-6 position by phenyl, methyl or trifluoromethyl group. These compounds were evaluated in order to identify the antiparasitic profile against trypomastigote and amastigote forms of Trypanosoma cruzi. The 4-carbohydrazide derivatives presented different profiles of activity. In the investigation of the chemical structure influence in the trypanocidal activity, the results indicated there are large lipophilicity and volume differences among these derivatives...
December 1, 2016: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/27924983/detection-of-the-tuberculosis-antigenic-marker-mannose-capped-lipoarabinomannan-in-pretreated-serum-by-surface-enhanced-raman-scattering
#7
Alexis C Crawford, Lars B Laurentius, Timothy S Mulvihill, Jennifer H Granger, John S Spencer, Delphi Chatterjee, Kimberly E Hanson, Marc D Porter
The ability to detect tuberculosis (TB) continues to be a global health care priority. This paper describes the development and preliminary assessment of the clinical accuracy of a heterogeneous immunoassay that integrates a serum pretreatment process with readout by surface-enhanced Raman scattering (SERS) for the low-level detection of mannose-capped lipoarabinomannan (ManLAM). ManLAM is a major virulence factor in the infectious pathology of Mycobacterium tuberculosis (Mtb) that has been found in the serum and other body fluids of infected patients...
December 7, 2016: Analyst
https://www.readbyqxmd.com/read/27924937/deep-sub-wavelength-nanofocusing-of-uv-visible-light-by-hyperbolic-metamaterials
#8
Minkyung Kim, Sunae So, Kan Yao, Yongmin Liu, Junsuk Rho
Confining light into a sub-wavelength area has been challenging due to the natural phenomenon of diffraction. In this paper, we report deep sub-wavelength focusing via dispersion engineering based on hyperbolic metamaterials. Hyperbolic metamaterials, which can be realized by alternating layers of metal and dielectric, are materials showing opposite signs of effective permittivity along the radial and the tangential direction. They can be designed to exhibit a nearly-flat open isofrequency curve originated from the large-negative permittivity in the radial direction and small-positive one in the tangential direction...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27924727/metabolomics-of-healthy-berry-fruits
#9
Gilda D Urso, Sonia Piacente, Cosimo Pizza, Paola Montoro
The consumption of berry-type fruits has become very popular in recent years because of their positive effects on human health. Berries are in fact widely known for their health-promoting benefits, including prevention of chronic disease, cardiovascular disease and cancer. Berries are a rich source of bioactive metabolites, such as vitamins, minerals, and phenolic compounds, mainly anthocyanins. Numerous in vitro and in vivo studies recognized the health effects of berries and their function as bioactive modulators of various cell functions associated with oxidative stress...
December 5, 2016: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/27924694/dimensions-of-activity-in-countertransference-and-therapist-reactions-therapist-reactions-during-sessions-with-depressed-patients
#10
Felicitas Datz, Karoline Parth, Christine Rohm, Simon Madanoglu, Charles Seidman, Henriette Löffler-Stastka
OBJECTIVES: This paper presents the interaction structure between the therapist's countertransference and the patient's affect based on identified dimensions of how therapists feel and react during sessions with depressed patients. METHODS: 639 sessions were audio-recorded and rated by trained raters. These recordings were obtained from the Munich Psychotherapy Study and analyzed with the PQS, the AREQ, and the TRQ/CTQ. RESULTS: Seven components with good to excellent internal consistency (Cronbach α = ...
December 2016: Zeitschrift Für Psychosomatische Medizin und Psychotherapie
https://www.readbyqxmd.com/read/27924656/assistive-technology-as-reading-interventions-for-children-with-reading-impairments-with-a-one-year-follow-up
#11
Emma Lindeblad, Staffan Nilsson, Stefan Gustafson, Idor Svensson
PURPOSE: This pilot study investigated the possible transfer effect on reading ability in children with reading difficulties after a systematic intervention to train and compensate for reading deficiencies by using applications in smartphones and tablets. The effects of using assistive technology (AT) one year after the interventions were completely studied. School related motivation, independent learning and family relations were also considered. METHOD: 35 pupils aged 10-12 years participated...
December 7, 2016: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/27924390/technical-standardization-of-laparoscopic-repair-of-morgagni-diaphragmatic-hernia-in-children-results-of-a-multicentric-survey-on-43-patients
#12
Ciro Esposito, Maria Escolino, Francois Varlet, Amulya Saxena, Sabine Irtan, Paul Philippe, Alessandro Settimi, Mariapina Cerulo, Holger Till, Francois Becmeur, George W Holcomb
BACKGROUND: This study aimed to standardize the surgical correction technique of congenital Morgagni diaphragmatic hernia (CMDH), analyzing the results of an international multicentric survey. METHODS: The medical records of 43 patients (29 boys, 14 girls) who underwent laparoscopic repair of CMDH in 8 pediatric surgery units in a 5-year period were retrospectively reviewed. Their average age was 3.3 years. Ten patients (23.2%) presented associated malformations: 9 Down syndrome (20...
December 6, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27924105/innovating-affordable-neonatal-care-equipment-for-use-at-scale
#13
REVIEW
V Sashi Kumar, V K Paul, K Sathasivam
The care of small and sick neonates requires biomedical technologies, such as devices that can keep babies warm (radiant warmers and incubators), resuscitate (self-inflating bags), track growth (weighing scales), treat jaundice (phototherapy units) and provide oxygen or respiratory support (hoods, continuous positive airway pressure (CPAP) devices and ventilators). Until the 1990s, most of these products were procured through import at a high cost and with little maintenance support. Emerging demand and an informal collaboration of neonatologists, engineers and entrepreneurs has led to the production of good quality equipment of several high-volume categories at affordable cost in India...
December 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27921637/facets-of-psychopathy-in-relation-to-trauma-exposure-and-posttraumatic-stress-symptomology-in-a-sample-of-incarcerated-male-offenders
#14
Russell Woodfield, Katie Dhingra, Daniel Boduszek, Agata Debowska
Purpose The purpose of this paper is to investigate the moderating role of psychopathy facets on the relationship between traumatic exposure and posttraumatic stress disorder (PTSD) symptomology. Design/methodology/approach Participants were male prisoners incarcerated in the UK. Findings The analysis revealed differential associations between the two facets of psychopathy, with potentially traumatic events and symptoms of PTSD. Specifically, neither primary psychopathy nor trauma exposure were significantly related to PTSD, while secondary psychopathy was positively and significantly related with PTSD symptoms...
December 19, 2016: International Journal of Prisoner Health
https://www.readbyqxmd.com/read/27921636/counterintuitive-findings-from-a-qualitative-study-of-mental-health-in-english-women-s-prisons
#15
Laura S Caulfield
Purpose Large numbers of women in prison report significant emotional and mental health problems, and there is evidence to suggest that the prison environment may exacerbate the incidence and severity of these issues (Armour, 2012). However, there has been limited exploration of the extent to which women's mental health problems exist prior to incarceration, whether symptoms first occur in incarceration, and how incarceration affects this. The paper aims to discuss these issues. Design/methodology/approach In-depth interviews were conducted with 43 women incarcerated in three English prisons and a thematic analysis of the data was conducted...
December 19, 2016: International Journal of Prisoner Health
https://www.readbyqxmd.com/read/27921423/-bariatric-surgeries-at-diabetic-patients
#16
Martin Haluzík
A worldwide increase in the prevalence of obesity and type 2 diabetes mellitus along with accompanying chronic, in particular cardiovascular, complications represents one of the leading challenges of current medicine. Despite major advances in diabetes pharmacotherapy, bariatric surgery remains the most effective treatment of diabetes. It not only markedly decreases body weight and improves glucose control but also induces diabetes remission in a significant percentage of patients. According to current recommendations, bariatric surgery is indicated in patients with 3rd degree obesity (even without any complications) or with 2nd degree obesity with complications (e...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27921329/preventive-dental-visiting-a-critical-interpretive-synthesis-of-theory-explaining-how-inequalities-arise
#17
Rebecca V Harris, Andrew Pennington, Margaret Whitehead
BACKGROUND: In many countries, those with lower socioeconomic status are disproportionately affected by poor oral health. This can be attributed, at least in part, to differences in preventive dental visiting. While several theories have been applied to the area, they generally fail to capture the recursive nature of dental visiting behaviour, and fall short of informing the design of complex interventions to tackle inequalities. OBJECTIVE: To undertake a systematic review and synthesis of theory in order to provide an overview of the pathways which bring about socioeconomic inequalities in early dental visiting, and identify possible intervention points...
December 6, 2016: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/27921188/erratum-to-an-international-position-paper-on-mother-infant-perinatal-mental-health-with-guidelines-for-clinical-practice
#18
Ian Brockington, Ruth Butterworth, Nine Glangeaud-Freudenthal
No abstract text is available yet for this article.
December 6, 2016: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/27921114/-postoperative-imaging-of-the-internal-auditory-canal-visualization-of-active-auditory-implants-german-version
#19
I Todt, G Rademacher, P Mittmann, S Mutze, A Ernst
BACKGROUND: Assessment of the internal auditory canal (IAC) and the cochlea is of central importance in neurotology. The artefacts and visibility of the different types of active auditory implants in MRI vary, due to their specific ferromagnetic components. Knowledge of the size of MRI artefacts and the options for handling these is important for the auditory rehabilitation of specific diseases (e. g., vestibular schwannoma). METHODS: The current paper is a literature review RESULTS: MRI assessment of the IAC and cochlea after surgical placement of an active auditory implant is feasible only with a percutaneous bone-anchored hearing aid (BAHA, Ponto)...
December 5, 2016: HNO
https://www.readbyqxmd.com/read/27919750/mapping-the-functional-connectome-in-traumatic-brain-injury-what-can-graph-metrics-tell-us
#20
Karen Caeyenberghs, Helena Verhelst, Adam Clemente, Peter H Wilson
OBJECTIVE: Traumatic brain injury (TBI) is associated with cognitive and motor deficits, and poses a significant personal, societal, and economic burden. One mechanism by which TBI is thought to affect cognition and behaviour is through changes in functional connectivity. Graph theory is a powerful framework for quantifying topological features of neuroimaging-derived functional networks. The objective of this paper is to review studies examining functional connectivity in TBI with an emphasis on graph theoretical analysis that is proving to be valuable in uncovering network abnormalities in this condition...
December 2, 2016: NeuroImage
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