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https://www.readbyqxmd.com/read/27912770/endometriosis-associated-clear-cell-carcinoma-arising-in-caesarean-section-scar-a-case-report-and-review-of-the-literature
#1
Gabriella Ferrandina, Eleonora Palluzzi, Francesco Fanfani, Stefano Gentileschi, Anna Lia Valentini, Maria Vittoria Mattoli, Ilaria Pennacchia, Giovanni Scambia, Gianfranco Zannoni
BACKGROUND: Malignant transformation has been reported in approximately 1% of the endometriosis cases; herein, we report a case of clear cell endometrial carcinoma arising from endometriosis foci located within a caesarean section scar. CASE PRESENTATION: In November 2014, a Caucasian, 44-year-old woman was transferred to our institution because of severe respiratory failure due to massive lung embolism and rapid enlargement of a subcutaneous suprapubic mass. Abdomino-pelvic magnetic resonance showed a 10...
December 3, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27906948/cervical-interlaminar-epidural-injections-at-high-doses-do-not-increase-optic-nerve-sheath-diameter-on-a-long-term-basis
#2
Hyunzu Kim, Joo Hyeon O, Sung-Jun Hong, Keun Man Shin, JungChan Park, Sang Soo Kang
BACKGROUND: Cervical epidural injection (CEI) is widely performed on patients with pain originating from the cervical spine. Studies have shown a good relationship between the optic nerve sheath diameter (ONSD) and the intracranial pressure (ICP). OBJECTIVE: The aim of this study was to evaluate the changes in the ONSD as a non-invasive surrogate marker of ICP after CEI. STUDY DESIGN: Prospective observational study. SETTING: Hospital and ambulatory pain clinic...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27906808/the-accuracy-of-large-loop-excision-of-the-transformation-zone-specimen-dimensions-in-determining-volume-a-multicentric-prospective-observational-study
#3
Xavier Carcopino, Julien Mancini, Walter Prendiville, Jean Gondry, Julien Chevreau, Gery Lamblin, Anthony Atallah, Vincent Lavoue, Claire Caradec, Jean-Jacques Baldauf, Angélique Bryand, Sébastien Henno, Aubert Agostini, Serge Douvier, Adelaide Jarniat, Didier Riethmuller, Anne Mendel, Jean-Luc Brun, Hajanarina Rakotomahenina, Lise Preaubert
OBJECTIVE: The aim of the study was to determine which mathematical formula of specimen dimensions is the most accurate method of determining volume of the excised specimen at loop excision of the transformation zone. MATERIALS AND METHODS: A multicenter prospective observational study was conducted. A total of 258 patients who had a loop excision of the transformation zone performed as treatment of cervical intraepithelial neoplasia 2-3 were included. The dimensions and the volume of the specimen were measured at the time of the procedure, before formaldehyde fixation...
November 30, 2016: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27906805/predictors-of-positive-margins-at-time-of-loop-electrosurgical-excision-procedure
#4
Jill Liss, Meredith Alston, Mona B Krull, Sara E Mazzoni
OBJECTIVE: The aim of the study was to identify factors associated with the presence of high-grade squamous intraepithelial lesion (HSIL) at surgical margins of loop electrosurgical excision procedure (LEEP) pathology specimens. MATERIALS AND METHODS: All women evaluated for lower genital tract disease at a single academic institution were prospectively entered into a database. The database was queried for all women who had a LEEP performed for indications within contemporary American Society of Colposcopy and Cervical Pathology guidelines between April 1, 2013, and April 30, 2015...
November 30, 2016: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27904452/virtual-modelling-of-novel-applicator-prototypes-for-cervical-cancer-brachytherapy
#5
Primoz Petric, Robert Hudej, Noora Al-Hammadi, Barbara Segedin
BACKGROUND: Standard applicators for cervical cancer Brachytherapy (BT) do not always achieve acceptable balance between target volume and normal tissue irradiation. We aimed to develop an innovative method of Target-volume Density Mapping (TDM) for modelling of novel applicator prototypes with optimal coverage characteristics. Patients and methods. Development of Contour-Analysis Tool 2 (CAT-2) software for TDM generation was the core priority of our task group. Main requests regarding software functionalities were formulated and guided the coding process...
December 1, 2016: Radiology and Oncology
https://www.readbyqxmd.com/read/27904404/phenolic-composition-antioxidant-capacity-and-in-vitro-cytotoxicity-assessment-of-fruit-wines
#6
Ana Ljevar, Natka Ćurko, Marina Tomašević, Kristina Radošević, Višnja Gaurina Srček, Karin Kovačević Ganić
Fruit wines contain a wide range of phenolic compounds with biological effects, but their composition and potential benefits to human health have been studied to the much lesser extent compared to grape wines. The aim of this research is to study the phenolic profile of different types of fruit wines and to evaluate their antioxidant and biological potential. Commercially available fruit wines from blackberry, cherry, raspberry, blackcurrant, strawberry and apple produced in Croatia were analyzed. To the best of our knowledge, this study represents the first comprehensive screening of Croatian fruit wines...
June 2016: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/27903087/two-cervical-preparation-regimens-prior-to-surgical-abortion-at-10-14-weeks-of-gestation-a-randomized-clinical-trial
#7
Qingyun Guo, Zhida Qian, Lili Huang
BACKGROUND: The aim of the study was to determine whether same-day cervical preparation with an osmotic dilator and misoprostol was as effective and safe as overnight cervical preparation for surgical abortions at 10-14 weeks. METHODS: Seventy women seeking surgical abortion at 10-14 weeks were allocated to receive one osmotic dilator 16-17 h or 6-7 h prior to an abortion. All women received misoprostol 400 μg orally 2 h before the abortion. RESULTS: The abortion time of the same-day group was 7...
December 1, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27900057/in-vitro-and-in-vivo-inhibition-of-tumor-cell-viability-by-combined-dihydroartemisinin-and-doxorubicin-treatment-and-the-underlying-mechanism
#8
Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
The natural extract artemisinin and its derivatives have good anticancer activity. The present study aimed to investigate the in vitro inhibitory effects of combined dihydroartemisinin (DHA) and doxorubicin (DOX) treatment on a variety of tumor cell lines (HeLa, OVCAR-3, MCF-7, PC-3 and A549), as well as the underlying mechanisms. In addition, the in vivo effects of DHA and DOX were evaluated using a mouse HeLa tumor model. The HeLa, OVCAR-3, MCF-7, PC-3 and A549 cells were treated with a combination of DHA and DOX, and the effect on cell viability was detected by Cell Counting kit-8...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27896208/relationship-between-maturation-indices-and-morphology-of-the-midpalatal-suture-obtained-using-cone-beam-computed-tomography-images
#9
Hong-Ik Jang, Sang-Cheol Kim, Jong-Moon Chae, Kyung-Hwa Kang, Jin-Woo Cho, Na-Young Chang, Keun-Young Lee, Jin-Hyoung Cho
OBJECTIVE: The purpose of this study was to determine whether predicting maturation of the midpalatal suture is possible by classifying its morphology on cone-beam computed tomography (CBCT) images and to investigate relationships with other developmental age indices. METHODS: The morphology of the midpalatal suture was assessed by using CBCT images of 99 patients. Axial plane images of the midpalatal suture were classified into five stages according to the classification scheme...
November 2016: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/27895683/salvage-interstitial-brachytherapy-based-on-computed-tomography-for-recurrent-cervical-cancer-after-radical-hysterectomy-and-adjuvant-radiation-therapy-case-presentations-and-introduction-of-the-technique
#10
Zhong-Shan Liu, Jie Guo, Yang-Zhi Zhao, Xia Lin, Bin Chen, Ming Zhang, Jiang-Ming Li, Xiao-Jun Ren, Bing-Ya Zhang, Tie-Jun Wang
PURPOSE: Locally recurring cervical cancer after surgery and adjuvant radiotherapy remains a major therapeutic challenge. This paper presents a new therapeutic technique for such patients: interstitial brachytherapy (BT) guided by real-time three-dimensional (3D) computed tomography (CT). MATERIAL AND METHODS: Sixteen patients with recurrent cervical cancer after radical surgery and adjuvant external-beam radiotherapy (EBRT) were included in this study. These patients underwent high-dose-rate (HDR) interstitial BT with free-hand placement of metal needles guided by real-time 3D-CT...
October 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/27895682/development-and-clinical-implementation-of-a-new-template-for-mri-based-intracavitary-interstitial-gynecologic-brachytherapy-for-locally-advanced-cervical-cancer-from-ct-based-mupit-to-the-mri-compatible-template-benidorm-ten-years-of-experience
#11
Silvia Rodríguez Villalba, Jose Richart Sancho, Antonio Otal Palacín, Jose Perez-Calatayud, Manuel Santos Ortega
PURPOSE: To study outcome and toxicity in 59 patients with locally advanced cervix carcinoma treated with computed tomography (CT)-based Martinez universal perineal interstitial template (MUPIT) and the new magnetic resonance imaging (MRI)-compatible template Benidorm (TB). MATERIAL AND METHODS: From December 2005 to October 2015, we retrospectively analyzed 34 patients treated with MUPIT and 25 treated with the TB. Six 4 Gy fractions were prescribed to the clinical target volume (CTV) combined with external beam radiotherapy (EBRT)...
October 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/27895681/rectal-separation-using-hydroxypropyl-methylcellulose-in-intracavitary-brachytherapy-of-cervical-cancer-an-innovative-approach
#12
Swapnendu Basu, Kazi Sazzad Manir, Abhishek Basu, Koushik Ghosh
PURPOSE: This study was initiated to prove feasibility of hydrogel application in recto-vaginal space in intracavitary brachytherapy (ICBT) of cervical cancer in order to reduce rectal toxicity. MATERIAL AND METHODS: In a case of stage IIB cervical cancer, after external beam radiotherapy (EBRT), we planned ICBT 7 Gy × 3 fractions. In 1(st) fraction (Plan 1), due to narrow separation between rectum and cervix (0.18 cm), only 5 Gy was delivered at point A (with high-risk clinical target volume [HR-CTV] D90 5...
October 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/27895435/optimal-mri-interval-for-detection-of-asymptomatic-recurrence-in-surgically-treated-early-cervical-cancer-by-use-of-a-mathematical-model
#13
A Laios, K Gubbala, R Lampe, A Tolis
INTRODUCTION: Applications of mathematical modeling may provide an insight into the timing of surveillance modalities. We aimed to determine the optimal magnetic resonance imaging (MRI) interval for the detection of surgically treated early cervical cancer asymptomatic recurrence by using a mathematical model for volumetric tumor growth time. METHODS: We assumed that tumor volume increases by a factor equal to the basis of natural logarithms (e~2.718) at constant time intervals...
January 2016: Hippokratia
https://www.readbyqxmd.com/read/27885472/a-prospective-randomized-trial-comparing-anterior-cervical-discectomy-and-fusion-versus-plate-only-open-door-laminoplasty-for-the-treatment-of-spinal-stenosis-in-degenerative-diseases
#14
Yun-Qi Jiang, Xi-Lei Li, Xiao-Gang Zhou, Chong Bian, Han-Ming Wang, Jian-Ming Huang, Jian Dong
OBJECTIVE: For three or more involved cervical levels, there is a debate over which approach yields the best outcomes for the treatment of multilevel cervical degenerative disease. Our objective is to compare the radiological and clinical outcomes of two treatments for multilevel cervical degenerative disease: anterior cervical discectomy and fusion (ACDF) versus plate-only open-door laminoplasty (laminoplasty). METHODS: Patients were randomized on a 1:1 randomization schedule with 17 patients in the ACDF group and 17 patients in the laminoplasty group...
November 24, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27882757/-contribution-of-sentinel-lymph-node-biopsy-to-treatment-of-locally-advanced-stages-of-cervical-cancers
#15
J Sláma, M Zikán, D Fischerová, R Kocián, A Germanová, F Frühauf, D Cibula
OBJECTIVE: Usage of sentinel lymph-node (SLN) concept in locally advanced cervical cancers might help to individualise management. According to SLN status could be patients refered to neoadjuvant chemotherapy (NAC) with subsequent surgery or to primary chemoradiation. The aim of our study was to evaluate sensitivity of SLN detection in locally advanced cervical cancers and to assess the impact of NAC on frequency of their metastatic involvement. DESIGN: Retrospective clinical study...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27876378/toxicities-and-dose-volume-histogram-parameters-of-mri-based-brachytherapy-for-cervical-cancer
#16
Youngkyong Kim, Yeon-Joo Kim, Joo-Young Kim, Young Kyung Lim, Chiyoung Jeong, Jonghwi Jeong, Meyoung Kim, Myong Cheol Lim, Sang-Soo Seo, Sang-Yoon Park
PURPOSE: To analyze the toxicities and dose-volume histogram parameters of external-beam and magnetic resonance imaging-based intracavitary brachytherapy in cervical cancer patients. METHODS AND MATERIALS: Acute and late toxicities were assessed in 135 patients divided into four groups: group 1, grade 0; group 2, grades 1-4; group 3, grades 0-1; and group 4, grades 2-4. The doses at the International Commission on Radiation Units and Measurements (DICRU) and minimum doses to the most exposed 0...
November 18, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27869624/surgical-outcome-and-prognostic-analysis-of-transoral-atlantoaxial-reduction-plate-system-for-basilar-invagination-a-voxel-based-morphometry-study
#17
Gejin Wei, Chenglong Shi, Zhiyun Wang, Hong Xia, Qingshui Yin, Zenghui Wu
BACKGROUND: The use of a transoral atlantoaxial reduction plate (TARP) system is an effective surgical approach for the treatment of basilar invagination. With the aim of improving the therapeutic efficacy of the TARP operation, we conducted a voxel-based morphometric study to quantitatively investigate the descent of the odontoid process and craniocervical volume changes. METHODS: We enrolled 20 patients with basilar invagination who underwent a TARP procedure...
October 19, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27863962/understanding-the-impact-of-pelvic-organ-motion-on-dose-delivered-to-target-volumes-during-imrt-for-cervical-cancer
#18
Gemma Eminowicz, Vasilis Rompokos, Christopher Stacey, Lisa Hall, Mary McCormack
BACKGROUND: Advanced radiotherapy techniques reduce normal tissue dose by conforming closely to target volumes. In cervical cancer radiotherapy, organ filling affects clinical target volume (CTV; cervix, uterus) position. This study estimates the dosimetric effect of this primary CTV position variation during chemoradiation. METHODS/MATERIALS: Twice weekly cone-beam computed tomography (CBCT) images of ten patients undergoing cervical chemoradiation were retrospectively analysed...
November 16, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27858077/-cone-beam-computed-tomography-evaluation-of-short-and-long-term-airway-changes-in-patients-with-skeletal-class-%C3%A2-malocclusion-treated-by-orthodontic-therapy-and-bimaxillary-surgery-with-or-without-mandibular-setback-surgery
#19
Hong-Wei Wang, Li-Yan Li, Su-Qing Qi, Ming Yan
PURPOSE: To evaluate the short-term and long-term effects of pharyngeal airway in skeletal Class Ⅲ malocclusion patients who underwent bimaxillary surgery or isolated mandibular setback-orthodontic treatment. METHODS: The sample included 54 patients (28 males, 26 females) who were diagnosed with skeletal Class Ⅲ malocclusion. Patents in group A (n=28) underwent mandibular setback surgery and orthodontic treatment. Cone-beam CT (CBCT) was taken at one week before treatment (T0), 6 months (T1) and 3 years after surgery (T2)...
August 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/27848197/12-month-efficacy-of-a-single-radiofrequency-ablation-on-autonomously-functioning-thyroid-nodules
#20
Stella Bernardi, Fulvio Stacul, Andrea Michelli, Fabiola Giudici, Giulia Zuolo, Nicolò de Manzini, Chiara Dobrinja, Fabrizio Zanconati, Bruno Fabris
PURPOSE: Radiofrequency ablation has been advocated as an alternative to radioiodine and/or surgery for the treatment of autonomously functioning benign thyroid nodules. However, only a few studies have measured radiofrequency ablation efficacy on autonomously functioning benign thyroid nodules. The aim of this work was to evaluate the 12-month efficacy of a single session of radiofrequency ablation (performed with the moving shot technique) on solitary autonomously functioning benign thyroid nodules...
November 15, 2016: Endocrine
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